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The map label for this gene is nccB [H]

Identifier: 146301670

GI number: 146301670

Start: 4682269

End: 4683399

Strand: Reverse

Name: nccB [H]

Synonym: Fjoh_3932

Alternate gene names: 146301670

Gene position: 4683399-4682269 (Counterclockwise)

Preceding gene: 146301671

Following gene: 146301669

Centisome position: 76.82

GC content: 35.1

Gene sequence:

>1131_bases
ATGAAAACTTATATAACAGCTGTTTTATGTCTTGTTTTGATGATATCATGCAAAAGTGATAAAAAAGAAGAACAAAAAAC
TGAAGTACAAAAACAGGAAAACACAATTGAGTTAAGCGATTCGCAGGTAAAAAACGCCAGATTGGCAACAGGAAATCCTG
AGGAGAAAAATGTAAAAGGAATTTTAGAACTGCAGGGAACCGTTACGGTGCCTCCCAAAAGTGTAGTGAGCGTAAGTATT
CCGTTAGGCGGCTACATTAAAAAAACCGATTTAATGGCCGGAATGCATGTTAGAAAAGGGCAGTTATTGGCTGTAGTGGA
AGATATGCAGTACATTCAGCTGCAGCAGGATTATTTAACTGCAAAAGAAAAATACCAGCTGTCTCAAAGTGAATATAACA
GACAAAAAGAATTGAATGCAAAAAAAGCAAGCAGTGATAAATTGTTTGAACAAACTGCTGCAGAAATGCAGACACAGCGT
ATTTATATGGCATCGCTTGCACAAAAACTTTCTTTGTCAGGAATTAATGTAAAAACATTATCGGCATCTAATATCAGTAA
AACGGTTTCGGTTCTTTCGCCCATAACCGGTTTGGTTTCTAAAGTAAATGTAAACGTTGGAAAATATATTTCTCCTACTG
ATATGCTTTTTGAATTAATGGAAACCAGCGATGTAGTTTTGGTTATGAATGCTTTTGAAAAAGATGTTCATCTGCTTTCT
GTTGGGCAGACTGTTTCTGTTTTTACCAATGCCGATCCTTCAAAAAAATATGCAGCAAAAATTGCCTACATCAATCAAAG
TCTTAACGGAGACCGTGCCGCCGAAGTTGTCTGTAAATTGAATGCATACAACAATGCATTAATTCCCGGTTTATTTATTA
ATGCCGAAGCTGAATTTGAAAACGAAAAAACGCTTACAGTTCCGGAAGATGCAATTGTAAAATGGCAGAATAAGTTTTAT
GTTTTTTCAAATACTGAAAACCAAAAATACAAAATGATTCCGGTAGAAACGGGAAGTTCTAGTAATGGATACCGACAGAT
TAAATCATCTTTAATAGATAAATCCTCAAAAATTGTAGTCAAAAATGCTTACACGCTTTTAATGACCTTTATGAATGGAG
GCGATAATTAA

Upstream 100 bases:

>100_bases
TATCAATCAGGCTGTAACGATAAAAAACGAATATTTAGACATGGTTAACAGTTATAATAAGGCTGTTAATACTCTTCGAA
CTCTTCAAAATTTATAAAAA

Downstream 100 bases:

>100_bases
CAATAAAACAAATAATACAAAACAAAAGGCTGTCAATTTAGACAGCCTTTTTGATTTATAAGCCTTCATTAAAAATTTAC
CTTATTCTGTTATAATAATA

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 376; Mature: 376

Protein sequence:

>376_residues
MKTYITAVLCLVLMISCKSDKKEEQKTEVQKQENTIELSDSQVKNARLATGNPEEKNVKGILELQGTVTVPPKSVVSVSI
PLGGYIKKTDLMAGMHVRKGQLLAVVEDMQYIQLQQDYLTAKEKYQLSQSEYNRQKELNAKKASSDKLFEQTAAEMQTQR
IYMASLAQKLSLSGINVKTLSASNISKTVSVLSPITGLVSKVNVNVGKYISPTDMLFELMETSDVVLVMNAFEKDVHLLS
VGQTVSVFTNADPSKKYAAKIAYINQSLNGDRAAEVVCKLNAYNNALIPGLFINAEAEFENEKTLTVPEDAIVKWQNKFY
VFSNTENQKYKMIPVETGSSSNGYRQIKSSLIDKSSKIVVKNAYTLLMTFMNGGDN

Sequences:

>Translated_376_residues
MKTYITAVLCLVLMISCKSDKKEEQKTEVQKQENTIELSDSQVKNARLATGNPEEKNVKGILELQGTVTVPPKSVVSVSI
PLGGYIKKTDLMAGMHVRKGQLLAVVEDMQYIQLQQDYLTAKEKYQLSQSEYNRQKELNAKKASSDKLFEQTAAEMQTQR
IYMASLAQKLSLSGINVKTLSASNISKTVSVLSPITGLVSKVNVNVGKYISPTDMLFELMETSDVVLVMNAFEKDVHLLS
VGQTVSVFTNADPSKKYAAKIAYINQSLNGDRAAEVVCKLNAYNNALIPGLFINAEAEFENEKTLTVPEDAIVKWQNKFY
VFSNTENQKYKMIPVETGSSSNGYRQIKSSLIDKSSKIVVKNAYTLLMTFMNGGDN
>Mature_376_residues
MKTYITAVLCLVLMISCKSDKKEEQKTEVQKQENTIELSDSQVKNARLATGNPEEKNVKGILELQGTVTVPPKSVVSVSI
PLGGYIKKTDLMAGMHVRKGQLLAVVEDMQYIQLQQDYLTAKEKYQLSQSEYNRQKELNAKKASSDKLFEQTAAEMQTQR
IYMASLAQKLSLSGINVKTLSASNISKTVSVLSPITGLVSKVNVNVGKYISPTDMLFELMETSDVVLVMNAFEKDVHLLS
VGQTVSVFTNADPSKKYAAKIAYINQSLNGDRAAEVVCKLNAYNNALIPGLFINAEAEFENEKTLTVPEDAIVKWQNKFY
VFSNTENQKYKMIPVETGSSSNGYRQIKSSLIDKSSKIVVKNAYTLLMTFMNGGDN

Specific function: Component of the NCC cation efflux system that confers resistance to nickel, cobalt and cadmium [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005695
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 41681; Mature: 41681

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTYITAVLCLVLMISCKSDKKEEQKTEVQKQENTIELSDSQVKNARLATGNPEEKNVKG
CHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCEEEECCCHHCCCEECCCCCCCCCCCE
ILELQGTVTVPPKSVVSVSIPLGGYIKKTDLMAGMHVRKGQLLAVVEDMQYIQLQQDYLT
EEEECCEEECCCCCEEEEECCCCCCEEHHHHHHCCEECCCCEEEEEHHHHHHHHHHHHHH
AKEKYQLSQSEYNRQKELNAKKASSDKLFEQTAAEMQTQRIYMASLAQKLSLSGINVKTL
HHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
SASNISKTVSVLSPITGLVSKVNVNVGKYISPTDMLFELMETSDVVLVMNAFEKDVHLLS
ECCCHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCEEEEE
VGQTVSVFTNADPSKKYAAKIAYINQSLNGDRAAEVVCKLNAYNNALIPGLFINAEAEFE
CCCEEEEEECCCCCHHHHEEEEEEECCCCCCHHEEEEEEEECCCCCCCCCEEEECCCCCC
NEKTLTVPEDAIVKWQNKFYVFSNTENQKYKMIPVETGSSSNGYRQIKSSLIDKSSKIVV
CCCEEECCHHHHEEECCEEEEEECCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCEEE
KNAYTLLMTFMNGGDN
EHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKTYITAVLCLVLMISCKSDKKEEQKTEVQKQENTIELSDSQVKNARLATGNPEEKNVKG
CHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCEEEECCCHHCCCEECCCCCCCCCCCE
ILELQGTVTVPPKSVVSVSIPLGGYIKKTDLMAGMHVRKGQLLAVVEDMQYIQLQQDYLT
EEEECCEEECCCCCEEEEECCCCCCEEHHHHHHCCEECCCCEEEEEHHHHHHHHHHHHHH
AKEKYQLSQSEYNRQKELNAKKASSDKLFEQTAAEMQTQRIYMASLAQKLSLSGINVKTL
HHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
SASNISKTVSVLSPITGLVSKVNVNVGKYISPTDMLFELMETSDVVLVMNAFEKDVHLLS
ECCCHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCEEEEE
VGQTVSVFTNADPSKKYAAKIAYINQSLNGDRAAEVVCKLNAYNNALIPGLFINAEAEFE
CCCEEEEEECCCCCHHHHEEEEEEECCCCCCHHEEEEEEEECCCCCCCCCEEEECCCCCC
NEKTLTVPEDAIVKWQNKFYVFSNTENQKYKMIPVETGSSSNGYRQIKSSLIDKSSKIVV
CCCEEECCHHHHEEECCEEEEEECCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCEEE
KNAYTLLMTFMNGGDN
EHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7961470 [H]