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The map label for this gene is luxQ [H]

Identifier: 146301663

GI number: 146301663

Start: 4674070

End: 4676058

Strand: Reverse

Name: luxQ [H]

Synonym: Fjoh_3925

Alternate gene names: 146301663

Gene position: 4676058-4674070 (Counterclockwise)

Preceding gene: 146301665

Following gene: 146301662

Centisome position: 76.7

GC content: 34.29

Gene sequence:

>1989_bases
ATGAAAACTCCAGAATTACCAATACCATCCAACGAACTAGAACGTTTAGCCGCTTTAAAACGTTACAATATACTAGATAC
GCTTCCTGACAATGCTTTTGACGATGCTACCAAACTAGTTTCTTATATATGCGGCGTGCCAATAGCGCATATTTCATTTA
TAGACGAAAGCAGGCAGTGGTTTAAATCTGAAATTGGAATTGGAATTTCTGAAGTGCCTCGTGAAATTTCTTTCTGCCGA
TATACCATTTTGGAATCAAAAATGGTTGAAATAAATGATACTTTTAAAAATGACAGGTTTAAAGACGATCCTAACGTAAG
GGGAGGTTTTAATGTGAGATTTTATGCTGGTGTTCCTTTAACAACACCAGACGGTTATAATATTGGTACTTTGTGCGCTG
TTGACCATGTTACGAAAGAATTAAATGAAGATCAGCGAAATGCACTTAGAATTGTTGCAAAACACGTAATCAGCCAGCTT
GAACTTGGAACAAAGAACGTTCAGCTAGATGCACAGAAAAAAATTGCAGAAAGAGCCGTATTGGCAAAAGATAGTTTTCT
GGCCAATATGAGTCATGAAATCAGAACGCCGTTAAATGCAATTATAGGTTTTACAGATCTGCTTGCGCAGACAAAACTTA
ATGCTGTGCAGCGAGATTATATAAACAGTGTGCAGATAGCAGGAGAAAATCTGCTTTTGATTGTGAATGATATTTTGGAT
TTGTCTAAAATGGAATCGGGTAATCTGACAATTGAAGCTGTGCCTTTCAATTTAAAAAACACCTTAAAACATGTTTATAA
TTTACTTAAAATAAAGGTTCCTAAAGAGGTTGAATTCAATCTTTTTCTTGATGCCGATATGCCGGAAATGGTTATTGGAG
ATGAAGGAAGATTAAACCAGATATTAGTTAATTTAATTGGTAATGCACTTAAGTTTACTCATGAAGGAGAGGTAACCGTT
TCTGTAAAAATGATTGAAGAAACAGAAACCCATTATTCGCTTAAATTCTCGGTTAAAGATACCGGAATTGGAATTCCTCC
CAAAAAACTTAAAACTATTTTTGAACGATTTACTCAGGCAGAAGACAGTACAACAAGAAAATTTGGAGGAACTGGTCTTG
GCCTTAATATTGTAAAGCAGTTAATCGAACTGCAGAATGCCGAAATTAATGTAAAAAGCGAGCAGAATAAAGGTTCAGAA
TTTTTCTTTGTTATTAATTATAAGAAATCAGATAACACCGAAGAAACAATTGAAGAATTGACAGGTGAAAGTCTGGGGAA
ACTTAAAATACTGCTTTGTGAAGATAATGTTTTGAACCAAAAACTGGTAAAAAGCGTTATGCAGAATTTTGGTTTTGAAC
TAGATATTGCAGAAAATGGCGAAGAAGGAATCGAATTTTTATTAAAAAATGAATATGATTTGGTTTTGATGGATCTTCAA
ATGCCAATTAAAGACGGATATCAGACTACTGAATATATTCGAAACGAAATGAACTCAACCATTCCGATTATTGCAATGAC
CGCGCATTCGCTTATGGGCGAACAAGAACGATGCTATAATGTAGGAATGGATGGTTATGTGCCAAAACCTTTTAAACAGC
CCGTACTTTTAGAAACCATAAAAACGGTGCTGAATCCAGATTATAAGCTTACACGAAAAAGAAGGGTAAATCTGTCTTTT
ATCAATGAAATGGCCTGCGGTGATTTAGGTTTTAGACAGGATATGATTAATCTTTTTATCGAAAAAATTCCTGCCGAAGA
AGCTTTACTCGAAGAAGCATTTAAAAATAATGATTATCTTAAAGTAAAAAATTTAGCGCATAATATGAGATCCAGCATGG
ATATGTTTATGCTTGATGATCTTAGTAATTGTTTAGCTGTTATTGAAGAAGAAGCCAGAAACGAAAAATTTTCTAGTGAA
GCTGCAGACAAGGCAGATATCTTTCATTGCGGTATAATTGAAGTAGTTAAATATTTAAAAGAGCTATGA

Upstream 100 bases:

>100_bases
TTGGTTTTCTCTGTCAAATTAACACCGTGAGTCATAAAATATTTTAATCCCGTTTTATCTCAAATTATTTTTATATTTAT
GCATTTTACCACTAGTTACA

Downstream 100 bases:

>100_bases
TAAAAGCGAAATAAATTTTAGCTTTACGTAAGTTTCTTGATTTTGCAAGATAAAGATTACCCCCAAAGACAAATTTTGAA
ACATGAGAATAATTTTAGCC

Product: GAF sensor hybrid histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 662; Mature: 662

Protein sequence:

>662_residues
MKTPELPIPSNELERLAALKRYNILDTLPDNAFDDATKLVSYICGVPIAHISFIDESRQWFKSEIGIGISEVPREISFCR
YTILESKMVEINDTFKNDRFKDDPNVRGGFNVRFYAGVPLTTPDGYNIGTLCAVDHVTKELNEDQRNALRIVAKHVISQL
ELGTKNVQLDAQKKIAERAVLAKDSFLANMSHEIRTPLNAIIGFTDLLAQTKLNAVQRDYINSVQIAGENLLLIVNDILD
LSKMESGNLTIEAVPFNLKNTLKHVYNLLKIKVPKEVEFNLFLDADMPEMVIGDEGRLNQILVNLIGNALKFTHEGEVTV
SVKMIEETETHYSLKFSVKDTGIGIPPKKLKTIFERFTQAEDSTTRKFGGTGLGLNIVKQLIELQNAEINVKSEQNKGSE
FFFVINYKKSDNTEETIEELTGESLGKLKILLCEDNVLNQKLVKSVMQNFGFELDIAENGEEGIEFLLKNEYDLVLMDLQ
MPIKDGYQTTEYIRNEMNSTIPIIAMTAHSLMGEQERCYNVGMDGYVPKPFKQPVLLETIKTVLNPDYKLTRKRRVNLSF
INEMACGDLGFRQDMINLFIEKIPAEEALLEEAFKNNDYLKVKNLAHNMRSSMDMFMLDDLSNCLAVIEEEARNEKFSSE
AADKADIFHCGIIEVVKYLKEL

Sequences:

>Translated_662_residues
MKTPELPIPSNELERLAALKRYNILDTLPDNAFDDATKLVSYICGVPIAHISFIDESRQWFKSEIGIGISEVPREISFCR
YTILESKMVEINDTFKNDRFKDDPNVRGGFNVRFYAGVPLTTPDGYNIGTLCAVDHVTKELNEDQRNALRIVAKHVISQL
ELGTKNVQLDAQKKIAERAVLAKDSFLANMSHEIRTPLNAIIGFTDLLAQTKLNAVQRDYINSVQIAGENLLLIVNDILD
LSKMESGNLTIEAVPFNLKNTLKHVYNLLKIKVPKEVEFNLFLDADMPEMVIGDEGRLNQILVNLIGNALKFTHEGEVTV
SVKMIEETETHYSLKFSVKDTGIGIPPKKLKTIFERFTQAEDSTTRKFGGTGLGLNIVKQLIELQNAEINVKSEQNKGSE
FFFVINYKKSDNTEETIEELTGESLGKLKILLCEDNVLNQKLVKSVMQNFGFELDIAENGEEGIEFLLKNEYDLVLMDLQ
MPIKDGYQTTEYIRNEMNSTIPIIAMTAHSLMGEQERCYNVGMDGYVPKPFKQPVLLETIKTVLNPDYKLTRKRRVNLSF
INEMACGDLGFRQDMINLFIEKIPAEEALLEEAFKNNDYLKVKNLAHNMRSSMDMFMLDDLSNCLAVIEEEARNEKFSSE
AADKADIFHCGIIEVVKYLKEL
>Mature_662_residues
MKTPELPIPSNELERLAALKRYNILDTLPDNAFDDATKLVSYICGVPIAHISFIDESRQWFKSEIGIGISEVPREISFCR
YTILESKMVEINDTFKNDRFKDDPNVRGGFNVRFYAGVPLTTPDGYNIGTLCAVDHVTKELNEDQRNALRIVAKHVISQL
ELGTKNVQLDAQKKIAERAVLAKDSFLANMSHEIRTPLNAIIGFTDLLAQTKLNAVQRDYINSVQIAGENLLLIVNDILD
LSKMESGNLTIEAVPFNLKNTLKHVYNLLKIKVPKEVEFNLFLDADMPEMVIGDEGRLNQILVNLIGNALKFTHEGEVTV
SVKMIEETETHYSLKFSVKDTGIGIPPKKLKTIFERFTQAEDSTTRKFGGTGLGLNIVKQLIELQNAEINVKSEQNKGSE
FFFVINYKKSDNTEETIEELTGESLGKLKILLCEDNVLNQKLVKSVMQNFGFELDIAENGEEGIEFLLKNEYDLVLMDLQ
MPIKDGYQTTEYIRNEMNSTIPIIAMTAHSLMGEQERCYNVGMDGYVPKPFKQPVLLETIKTVLNPDYKLTRKRRVNLSF
INEMACGDLGFRQDMINLFIEKIPAEEALLEEAFKNNDYLKVKNLAHNMRSSMDMFMLDDLSNCLAVIEEEARNEKFSSE
AADKADIFHCGIIEVVKYLKEL

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=284, Percent_Identity=41.5492957746479, Blast_Score=223, Evalue=3e-59,
Organism=Escherichia coli, GI48994928, Length=375, Percent_Identity=37.3333333333333, Blast_Score=219, Evalue=5e-58,
Organism=Escherichia coli, GI1788713, Length=465, Percent_Identity=28.8172043010753, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI87081816, Length=466, Percent_Identity=30.0429184549356, Blast_Score=183, Evalue=3e-47,
Organism=Escherichia coli, GI145693157, Length=257, Percent_Identity=36.9649805447471, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1786600, Length=234, Percent_Identity=31.6239316239316, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI1788393, Length=234, Percent_Identity=27.3504273504274, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI1790436, Length=237, Percent_Identity=28.2700421940928, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1786912, Length=256, Percent_Identity=23.828125, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1786783, Length=225, Percent_Identity=28.8888888888889, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87082012, Length=123, Percent_Identity=30.0813008130081, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788549, Length=245, Percent_Identity=24.0816326530612, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI1790300, Length=254, Percent_Identity=24.4094488188976, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1790861, Length=218, Percent_Identity=27.5229357798165, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1790346, Length=240, Percent_Identity=26.6666666666667, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1786784, Length=118, Percent_Identity=27.9661016949153, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1787894, Length=227, Percent_Identity=26.431718061674, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1788279, Length=202, Percent_Identity=26.2376237623762, Blast_Score=63, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=123, Percent_Identity=37.3983739837398, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 75035; Mature: 75035

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS50894 HPT ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTPELPIPSNELERLAALKRYNILDTLPDNAFDDATKLVSYICGVPIAHISFIDESRQW
CCCCCCCCCHHHHHHHHHHHHHCHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHH
FKSEIGIGISEVPREISFCRYTILESKMVEINDTFKNDRFKDDPNVRGGFNVRFYAGVPL
HHHHHCCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCC
TTPDGYNIGTLCAVDHVTKELNEDQRNALRIVAKHVISQLELGTKNVQLDAQKKIAERAV
CCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHH
LAKDSFLANMSHEIRTPLNAIIGFTDLLAQTKLNAVQRDYINSVQIAGENLLLIVNDILD
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCEEEEEHHHHH
LSKMESGNLTIEAVPFNLKNTLKHVYNLLKIKVPKEVEFNLFLDADMPEMVIGDEGRLNQ
HHHCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEECCCCHHHH
ILVNLIGNALKFTHEGEVTVSVKMIEETETHYSLKFSVKDTGIGIPPKKLKTIFERFTQA
HHHHHHHHHHEEECCCCEEEEEEEEECCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHCC
EDSTTRKFGGTGLGLNIVKQLIELQNAEINVKSEQNKGSEFFFVINYKKSDNTEETIEEL
CCCHHHHCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCEEEEEEEECCCCCHHHHHHHH
TGESLGKLKILLCEDNVLNQKLVKSVMQNFGFELDIAENGEEGIEFLLKNEYDLVLMDLQ
CCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHCCCCCEEEEEEE
MPIKDGYQTTEYIRNEMNSTIPIIAMTAHSLMGEQERCYNVGMDGYVPKPFKQPVLLETI
CCCCCCCHHHHHHHHHHCCCCCEEEEEHHHHHCCHHHHHCCCCCCCCCCCCCCCHHHHHH
KTVLNPDYKLTRKRRVNLSFINEMACGDLGFRQDMINLFIEKIPAEEALLEEAFKNNDYL
HHHHCCCHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCE
KVKNLAHNMRSSMDMFMLDDLSNCLAVIEEEARNEKFSSEAADKADIFHCGIIEVVKYLK
EHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHEEECCHHHHHHHHH
EL
CC
>Mature Secondary Structure
MKTPELPIPSNELERLAALKRYNILDTLPDNAFDDATKLVSYICGVPIAHISFIDESRQW
CCCCCCCCCHHHHHHHHHHHHHCHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHH
FKSEIGIGISEVPREISFCRYTILESKMVEINDTFKNDRFKDDPNVRGGFNVRFYAGVPL
HHHHHCCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCC
TTPDGYNIGTLCAVDHVTKELNEDQRNALRIVAKHVISQLELGTKNVQLDAQKKIAERAV
CCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHH
LAKDSFLANMSHEIRTPLNAIIGFTDLLAQTKLNAVQRDYINSVQIAGENLLLIVNDILD
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCEEEEEHHHHH
LSKMESGNLTIEAVPFNLKNTLKHVYNLLKIKVPKEVEFNLFLDADMPEMVIGDEGRLNQ
HHHCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEECCCCHHHH
ILVNLIGNALKFTHEGEVTVSVKMIEETETHYSLKFSVKDTGIGIPPKKLKTIFERFTQA
HHHHHHHHHHEEECCCCEEEEEEEEECCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHCC
EDSTTRKFGGTGLGLNIVKQLIELQNAEINVKSEQNKGSEFFFVINYKKSDNTEETIEEL
CCCHHHHCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCEEEEEEEECCCCCHHHHHHHH
TGESLGKLKILLCEDNVLNQKLVKSVMQNFGFELDIAENGEEGIEFLLKNEYDLVLMDLQ
CCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHCCCCCEEEEEEE
MPIKDGYQTTEYIRNEMNSTIPIIAMTAHSLMGEQERCYNVGMDGYVPKPFKQPVLLETI
CCCCCCCHHHHHHHHHHCCCCCEEEEEHHHHHCCHHHHHCCCCCCCCCCCCCCCHHHHHH
KTVLNPDYKLTRKRRVNLSFINEMACGDLGFRQDMINLFIEKIPAEEALLEEAFKNNDYL
HHHHCCCHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCE
KVKNLAHNMRSSMDMFMLDDLSNCLAVIEEEARNEKFSSEAADKADIFHCGIIEVVKYLK
EHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHEEECCHHHHHHHHH
EL
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA