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The map label for this gene is phoB [H]

Identifier: 146301662

GI number: 146301662

Start: 4673622

End: 4673987

Strand: Reverse

Name: phoB [H]

Synonym: Fjoh_3924

Alternate gene names: 146301662

Gene position: 4673987-4673622 (Counterclockwise)

Preceding gene: 146301663

Following gene: 146301661

Centisome position: 76.66

GC content: 35.25

Gene sequence:

>366_bases
ATGAGAATAATTTTAGCCGAAGATAATGATATCCTGCGCAAATCATTATCCTTTTTCTTAGAGTCTAAAGGATTTACAGT
TGACCAGTTTTCTGATGGTAAAGACGCACTGGAAGCTATTAAAAATAATGGCTGCGATTTAATCCTTACAGACATAAATA
TGCCGGGCATAAGCGGAATGGAAATTACGCAGTATGTTAGGCAGACCCTAAATTCAGATATTCCTGTAATTATACTTACT
TCTTCGGGAGTTGAACAGACAGAGCTTGATTCTTTTGACATAGGTGCAAATGAATTTATAGCAAAACCTATAAGTCCGGC
CGTACTTTTGGTGAGAATTAATAAATTACTAAAAACACGTGTTTAA

Upstream 100 bases:

>100_bases
TATTTAAAAGAGCTATGATAAAAGCGAAATAAATTTTAGCTTTACGTAAGTTTCTTGATTTTGCAAGATAAAGATTACCC
CCAAAGACAAATTTTGAAAC

Downstream 100 bases:

>100_bases
TGAGATTTATATACTATTCAATTATCCTGTTGTTTATTTCTATTACTGCGGCAGGACAGGAAATTAATATTGATGAAACT
CTGGCAAATGCAAGAAGTGA

Product: response regulator receiver protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 121; Mature: 121

Protein sequence:

>121_residues
MRIILAEDNDILRKSLSFFLESKGFTVDQFSDGKDALEAIKNNGCDLILTDINMPGISGMEITQYVRQTLNSDIPVIILT
SSGVEQTELDSFDIGANEFIAKPISPAVLLVRINKLLKTRV

Sequences:

>Translated_121_residues
MRIILAEDNDILRKSLSFFLESKGFTVDQFSDGKDALEAIKNNGCDLILTDINMPGISGMEITQYVRQTLNSDIPVIILT
SSGVEQTELDSFDIGANEFIAKPISPAVLLVRINKLLKTRV
>Mature_121_residues
MRIILAEDNDILRKSLSFFLESKGFTVDQFSDGKDALEAIKNNGCDLILTDINMPGISGMEITQYVRQTLNSDIPVIILT
SSGVEQTELDSFDIGANEFIAKPISPAVLLVRINKLLKTRV

Specific function: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by phoB and phoR when phosphate is limited [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=118, Percent_Identity=33.8983050847458, Blast_Score=83, Evalue=6e-18,
Organism=Escherichia coli, GI1790860, Length=116, Percent_Identity=31.0344827586207, Blast_Score=72, Evalue=8e-15,
Organism=Escherichia coli, GI87082012, Length=118, Percent_Identity=33.8983050847458, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1788394, Length=117, Percent_Identity=30.7692307692308, Blast_Score=68, Evalue=2e-13,
Organism=Escherichia coli, GI1789402, Length=118, Percent_Identity=27.9661016949153, Blast_Score=67, Evalue=4e-13,
Organism=Escherichia coli, GI145693157, Length=105, Percent_Identity=32.3809523809524, Blast_Score=66, Evalue=5e-13,
Organism=Escherichia coli, GI1786784, Length=118, Percent_Identity=28.8135593220339, Blast_Score=66, Evalue=6e-13,
Organism=Escherichia coli, GI1789809, Length=117, Percent_Identity=29.0598290598291, Blast_Score=64, Evalue=2e-12,
Organism=Escherichia coli, GI1790863, Length=116, Percent_Identity=28.448275862069, Blast_Score=64, Evalue=3e-12,
Organism=Escherichia coli, GI1787229, Length=115, Percent_Identity=28.695652173913, Blast_Score=64, Evalue=3e-12,
Organism=Escherichia coli, GI1787375, Length=118, Percent_Identity=24.5762711864407, Blast_Score=62, Evalue=1e-11,
Organism=Escherichia coli, GI1788713, Length=116, Percent_Identity=31.0344827586207, Blast_Score=62, Evalue=1e-11,
Organism=Escherichia coli, GI1788191, Length=120, Percent_Identity=25.8333333333333, Blast_Score=62, Evalue=1e-11,
Organism=Escherichia coli, GI1790552, Length=118, Percent_Identity=25.4237288135593, Blast_Score=61, Evalue=3e-11,
Organism=Escherichia coli, GI1790299, Length=109, Percent_Identity=31.1926605504587, Blast_Score=60, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR011879
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 13374; Mature: 13374

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIILAEDNDILRKSLSFFLESKGFTVDQFSDGKDALEAIKNNGCDLILTDINMPGISGM
CEEEEECCCHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCH
EITQYVRQTLNSDIPVIILTSSGVEQTELDSFDIGANEFIAKPISPAVLLVRINKLLKTR
HHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHCC
V
C
>Mature Secondary Structure
MRIILAEDNDILRKSLSFFLESKGFTVDQFSDGKDALEAIKNNGCDLILTDINMPGISGM
CEEEEECCCHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCH
EITQYVRQTLNSDIPVIILTSSGVEQTELDSFDIGANEFIAKPISPAVLLVRINKLLKTR
HHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHCC
V
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]