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The map label for this gene is hypA [H]

Identifier: 146301644

GI number: 146301644

Start: 4651353

End: 4651694

Strand: Reverse

Name: hypA [H]

Synonym: Fjoh_3905

Alternate gene names: 146301644

Gene position: 4651694-4651353 (Counterclockwise)

Preceding gene: 146301654

Following gene: 146301643

Centisome position: 76.3

GC content: 33.04

Gene sequence:

>342_bases
ATGCATGAGCTTTCGGTTGTTACTTCGATTGTGAAAATTGTTCAACAAGAAGTAGATAAGATAAAAGGTAAAAGCGTATT
AGAACTCTATCTGGAAATTGGAAAATTATCAGGAGTAGAAATGTCTTCTTTTTATTTTGTGTGGCCGCAATGCATTAATG
GAAATATTTTAAGCAACACGAAATTATTTGTGGAAGAACCAGAAGGAAAAGCCCGGTGTGCAGAATGTGAAACGGAATTT
TACATTGAAAAAAGTTTTGACAGCTGCCCAAATTGTAAGAGTCCGTTTAAGGAAATTATTGCCGGCAGAGAATTGAAAAT
AAAGAAAATAATCATAAAATAA

Upstream 100 bases:

>100_bases
CTATTTAAACATTTGATTCTCGGAAGTGATAATTATCAGGTTTTGATTTGATTCTTTGAATTATCTTTCGCGGTTGTAAT
AATCTGTTAAAAAAAAACAA

Downstream 100 bases:

>100_bases
ACTGAGTTATGTGTACCACTTGCGGATGCAGTTCTGATGAAAACGAAATACGATTTACCAAAATAGGAGAGAAACAATTC
CATTCTCATTCCGGTCACTA

Product: hydrogenase expression/synthesis, HypA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 113; Mature: 113

Protein sequence:

>113_residues
MHELSVVTSIVKIVQQEVDKIKGKSVLELYLEIGKLSGVEMSSFYFVWPQCINGNILSNTKLFVEEPEGKARCAECETEF
YIEKSFDSCPNCKSPFKEIIAGRELKIKKIIIK

Sequences:

>Translated_113_residues
MHELSVVTSIVKIVQQEVDKIKGKSVLELYLEIGKLSGVEMSSFYFVWPQCINGNILSNTKLFVEEPEGKARCAECETEF
YIEKSFDSCPNCKSPFKEIIAGRELKIKKIIIK
>Mature_113_residues
MHELSVVTSIVKIVQQEVDKIKGKSVLELYLEIGKLSGVEMSSFYFVWPQCINGNILSNTKLFVEEPEGKARCAECETEF
YIEKSFDSCPNCKSPFKEIIAGRELKIKKIIIK

Specific function: Probably plays a role in an hydrogenase nickel cofactor insertion step [H]

COG id: COG0375

COG function: function code R; Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypA/hybF family [H]

Homologues:

Organism=Escherichia coli, GI1789081, Length=113, Percent_Identity=29.2035398230088, Blast_Score=63, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000688 [H]

Pfam domain/function: PF01155 HypA [H]

EC number: NA

Molecular weight: Translated: 12864; Mature: 12864

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
4.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHELSVVTSIVKIVQQEVDKIKGKSVLELYLEIGKLSGVEMSSFYFVWPQCINGNILSNT
CCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEECCEEEECHHHCCCCEECCC
KLFVEEPEGKARCAECETEFYIEKSFDSCPNCKSPFKEIIAGRELKIKKIIIK
EEEEECCCCCCHHHCCCHHEEEECCCCCCCCCCHHHHHHHCCCCEEEEEEECC
>Mature Secondary Structure
MHELSVVTSIVKIVQQEVDKIKGKSVLELYLEIGKLSGVEMSSFYFVWPQCINGNILSNT
CCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEECCEEEECHHHCCCCEECCC
KLFVEEPEGKARCAECETEFYIEKSFDSCPNCKSPFKEIIAGRELKIKKIIIK
EEEEECCCCCCHHHCCCHHEEEECCCCCCCCCCHHHHHHHCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA