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The map label for this gene is erg3 [H]

Identifier: 146301251

GI number: 146301251

Start: 4184055

End: 4185335

Strand: Direct

Name: erg3 [H]

Synonym: Fjoh_3509

Alternate gene names: 146301251

Gene position: 4184055-4185335 (Clockwise)

Preceding gene: 146301250

Following gene: 146301252

Centisome position: 68.63

GC content: 33.65

Gene sequence:

>1281_bases
ATGGAAGAATATGGTAAAATATTAATTATTGCAATGCCTGTTTTTTTAGTTCTAATTGTAATTGAAAAACTTTACGGCAT
TTACAAAAAGAACGATACTGCTCCATTAATTGACAGCGTTTCCAGTATTAGTTCCGGAATTACCAATTCTGTAAAAGACG
TTTTAGGACTCAGCATTACTTTTCTTTCATATGAGTGGATGGTTTCTAAAATTGCACTTTTTCATCAGGAAGCCACAGTT
CTATCTTACATCATTGCCTTTTTTGTTATTGATTTCTACGGATATTGGAGTCATCGACTGGCTCATCAAATTAACTTTTT
TTGGAATAAACACGCCATTCACCACAGCAGTGAAGAGTTTAATCTTGCCTGCGCGCTGCGCCAGCCTATAGCGAGTCTGG
TTAATTTATTTACTTTTCTGCTTATTCCGGCAGCATTATTAGGAGTTCCGGCTTCTGTAATTGCCATAACACTTCCGCTC
CATTTATTTTTACAGTTTTGGTATCATACCAAACACATTAAAAAAATGGGATTTGTAGAAAAAATTCTCGTAACGCCTTC
GCATCATCGGGTTCATCATGCCATAAATCCTGAATATTTAGATAAAAACCATTCGCAGATATTTATTTTCTGGGATAAAC
TTTTTGGAACATTTCAGGAAGAATTAGACGATATTCCTCCGGTTTTTGGAATTACAAGACCTGCCAATACATGGAATCCG
ATAAAAATAAATTTTCAGCATTTAACTTTATTAATAAAAGACGCCTGGCGAGCCGAAAGCTGGAAAGATAAACTAACCAT
TTGGTTTAAACCAACAGGATGGCGGCCTGAAAATTTCGAAGAAAAATATCCGGTTAACAAAATCGAAAATGTATTTGATT
TTGAAAAATACGGCACACAAAATTCTCAAAAACTCATTTATTGGTCAGTTGCTCAAATTTTAATTACACTTTTGTTTGTG
AGTTATTTATTTGAGAATATTGCCCAAATTGGTCTGCCTAATATTTTCGTCTATGGGTTCTTTATTTTTATAACCATTTA
CAGCAGCTCTGAACTAATGGATAAAAGCAGATTTGCTATTGTCTGGGAAGGTTTTAGATTGTCTCTCGCGACAGCCGTAA
TTTTATTTTACGGCGATTGGTTTGGTCTCAAAACCGTTTTCTCTTTAAGTAATTATATAATTTTAGGTTATTTAAGTGTA
TCTTTTTTAATAACGATTTACTTTGTAACTGTAGATTTTAAAACTAACCAAAATCAAACCATAAATTCACAAACCGCGTA
A

Upstream 100 bases:

>100_bases
TTTTGGAAGCTGGACTAAGCGCTGAAATTGTTTAATTTACCAATAATTTAAAAAACATTCTATTTTATTTTATATTTGAA
ATAAAATAGAATGTTTTTTT

Downstream 100 bases:

>100_bases
TGAAAAATATTGTATTTTTTAAAATTTATACTGCATACTGCTTTATTTATCTGCTTCTTTTATATCTGGGATATGAAAGT
TTAGACTGTTACCTAAAACC

Product: sterol desaturase-like protein

Products: NA

Alternate protein names: Sterol-C5-desaturase [H]

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MEEYGKILIIAMPVFLVLIVIEKLYGIYKKNDTAPLIDSVSSISSGITNSVKDVLGLSITFLSYEWMVSKIALFHQEATV
LSYIIAFFVIDFYGYWSHRLAHQINFFWNKHAIHHSSEEFNLACALRQPIASLVNLFTFLLIPAALLGVPASVIAITLPL
HLFLQFWYHTKHIKKMGFVEKILVTPSHHRVHHAINPEYLDKNHSQIFIFWDKLFGTFQEELDDIPPVFGITRPANTWNP
IKINFQHLTLLIKDAWRAESWKDKLTIWFKPTGWRPENFEEKYPVNKIENVFDFEKYGTQNSQKLIYWSVAQILITLLFV
SYLFENIAQIGLPNIFVYGFFIFITIYSSSELMDKSRFAIVWEGFRLSLATAVILFYGDWFGLKTVFSLSNYIILGYLSV
SFLITIYFVTVDFKTNQNQTINSQTA

Sequences:

>Translated_426_residues
MEEYGKILIIAMPVFLVLIVIEKLYGIYKKNDTAPLIDSVSSISSGITNSVKDVLGLSITFLSYEWMVSKIALFHQEATV
LSYIIAFFVIDFYGYWSHRLAHQINFFWNKHAIHHSSEEFNLACALRQPIASLVNLFTFLLIPAALLGVPASVIAITLPL
HLFLQFWYHTKHIKKMGFVEKILVTPSHHRVHHAINPEYLDKNHSQIFIFWDKLFGTFQEELDDIPPVFGITRPANTWNP
IKINFQHLTLLIKDAWRAESWKDKLTIWFKPTGWRPENFEEKYPVNKIENVFDFEKYGTQNSQKLIYWSVAQILITLLFV
SYLFENIAQIGLPNIFVYGFFIFITIYSSSELMDKSRFAIVWEGFRLSLATAVILFYGDWFGLKTVFSLSNYIILGYLSV
SFLITIYFVTVDFKTNQNQTINSQTA
>Mature_426_residues
MEEYGKILIIAMPVFLVLIVIEKLYGIYKKNDTAPLIDSVSSISSGITNSVKDVLGLSITFLSYEWMVSKIALFHQEATV
LSYIIAFFVIDFYGYWSHRLAHQINFFWNKHAIHHSSEEFNLACALRQPIASLVNLFTFLLIPAALLGVPASVIAITLPL
HLFLQFWYHTKHIKKMGFVEKILVTPSHHRVHHAINPEYLDKNHSQIFIFWDKLFGTFQEELDDIPPVFGITRPANTWNP
IKINFQHLTLLIKDAWRAESWKDKLTIWFKPTGWRPENFEEKYPVNKIENVFDFEKYGTQNSQKLIYWSVAQILITLLFV
SYLFENIAQIGLPNIFVYGFFIFITIYSSSELMDKSRFAIVWEGFRLSLATAVILFYGDWFGLKTVFSLSNYIILGYLSV
SFLITIYFVTVDFKTNQNQTINSQTA

Specific function: Unknown

COG id: COG3000

COG function: function code I; Sterol desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sterol desaturase family [H]

Homologues:

Organism=Homo sapiens, GI51972212, Length=373, Percent_Identity=34.0482573726542, Blast_Score=200, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI25144659, Length=227, Percent_Identity=34.3612334801762, Blast_Score=135, Evalue=5e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006694 [H]

Pfam domain/function: PF04116 FA_hydroxylase [H]

EC number: NA

Molecular weight: Translated: 49455; Mature: 49455

Theoretical pI: Translated: 7.55; Mature: 7.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEYGKILIIAMPVFLVLIVIEKLYGIYKKNDTAPLIDSVSSISSGITNSVKDVLGLSIT
CCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHH
FLSYEWMVSKIALFHQEATVLSYIIAFFVIDFYGYWSHRLAHQINFFWNKHAIHHSSEEF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCH
NLACALRQPIASLVNLFTFLLIPAALLGVPASVIAITLPLHLFLQFWYHTKHIKKMGFVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KILVTPSHHRVHHAINPEYLDKNHSQIFIFWDKLFGTFQEELDDIPPVFGITRPANTWNP
HHHCCCCCCCEECCCCHHHCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
IKINFQHLTLLIKDAWRAESWKDKLTIWFKPTGWRPENFEEKYPVNKIENVFDFEKYGTQ
EEEEHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
NSQKLIYWSVAQILITLLFVSYLFENIAQIGLPNIFVYGFFIFITIYSSSELMDKSRFAI
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHCCCCEEE
VWEGFRLSLATAVILFYGDWFGLKTVFSLSNYIILGYLSVSFLITIYFVTVDFKTNQNQT
EEECHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCC
INSQTA
CCCCCC
>Mature Secondary Structure
MEEYGKILIIAMPVFLVLIVIEKLYGIYKKNDTAPLIDSVSSISSGITNSVKDVLGLSIT
CCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHH
FLSYEWMVSKIALFHQEATVLSYIIAFFVIDFYGYWSHRLAHQINFFWNKHAIHHSSEEF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCH
NLACALRQPIASLVNLFTFLLIPAALLGVPASVIAITLPLHLFLQFWYHTKHIKKMGFVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KILVTPSHHRVHHAINPEYLDKNHSQIFIFWDKLFGTFQEELDDIPPVFGITRPANTWNP
HHHCCCCCCCEECCCCHHHCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
IKINFQHLTLLIKDAWRAESWKDKLTIWFKPTGWRPENFEEKYPVNKIENVFDFEKYGTQ
EEEEHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
NSQKLIYWSVAQILITLLFVSYLFENIAQIGLPNIFVYGFFIFITIYSSSELMDKSRFAI
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHCCCCEEE
VWEGFRLSLATAVILFYGDWFGLKTVFSLSNYIILGYLSVSFLITIYFVTVDFKTNQNQT
EEECHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCC
INSQTA
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]