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The map label for this gene is coaE [H]

Identifier: 146301204

GI number: 146301204

Start: 4128543

End: 4129139

Strand: Reverse

Name: coaE [H]

Synonym: Fjoh_3462

Alternate gene names: 146301204

Gene position: 4129139-4128543 (Counterclockwise)

Preceding gene: 146301205

Following gene: 146301203

Centisome position: 67.73

GC content: 30.32

Gene sequence:

>597_bases
ATGACAAAAATAATTGGCCTGACTGGTGGAATAGGAAGCGGTAAAACAACAATTGCCAGTTTTTTTAAAGAAGAAGGTGT
TCCTGTTTATATTGCTGATGATGAAGCTAAAAAGGTAATGCAGTCATCAGAAATTATAAATCAAATAAAAACTTCTTTTG
GAGAGTCGCTCTTTGATAATAATGTTTTAAACCGGTCAAAATTAGCCGAAATAGTATTTAACAATAAAGAACAATTAGAA
AAGTTAAATGCAATTGTTCATCCTGCTGTAAAAAAAGATTTTCAATCCTGGCTTTTACAAAATAAAGGAATGGATTTTGT
GGTATATGAAGCAGCTATTTTGTTTGAAAGCGGCAAGTATAAAGAATTTGATTATATAGTTACCGTTACAGCACCTGAAG
ACGTAAGAATTGAAAGAGTAATGAAACGCGACAATTCTACAAGAGAACAGGTTTTAAGCAGAATGAAAATGCAGTGGAAT
GACGAAAAACGAATTTCTTTAAGTAATTTTGTAATTAATAACAGTAATCTTAAAATTGCGCGAGAAGAAGTTGGTGAAAT
TCTTAAAATTTTGAAAATAAAACAAAAACAGTCTTAA

Upstream 100 bases:

>100_bases
TATGGTTACGGAACAGGATTTTTGGAATCTTTTGTAAAAGTCATTTTATTAAAGAAAAAACCACAAGAAGCTTTTCCACG
TATGTTTTTTAAAATATAAT

Downstream 100 bases:

>100_bases
ATGTTAATATTTGGTTAATGTATTATTTAGTATATTGTTAAAATATTAATTTTGTTTCGATGAATAAATTATTTTTTAGA
ATACTTGTTTTATTGATGAG

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 198; Mature: 197

Protein sequence:

>198_residues
MTKIIGLTGGIGSGKTTIASFFKEEGVPVYIADDEAKKVMQSSEIINQIKTSFGESLFDNNVLNRSKLAEIVFNNKEQLE
KLNAIVHPAVKKDFQSWLLQNKGMDFVVYEAAILFESGKYKEFDYIVTVTAPEDVRIERVMKRDNSTREQVLSRMKMQWN
DEKRISLSNFVINNSNLKIAREEVGEILKILKIKQKQS

Sequences:

>Translated_198_residues
MTKIIGLTGGIGSGKTTIASFFKEEGVPVYIADDEAKKVMQSSEIINQIKTSFGESLFDNNVLNRSKLAEIVFNNKEQLE
KLNAIVHPAVKKDFQSWLLQNKGMDFVVYEAAILFESGKYKEFDYIVTVTAPEDVRIERVMKRDNSTREQVLSRMKMQWN
DEKRISLSNFVINNSNLKIAREEVGEILKILKIKQKQS
>Mature_197_residues
TKIIGLTGGIGSGKTTIASFFKEEGVPVYIADDEAKKVMQSSEIINQIKTSFGESLFDNNVLNRSKLAEIVFNNKEQLEK
LNAIVHPAVKKDFQSWLLQNKGMDFVVYEAAILFESGKYKEFDYIVTVTAPEDVRIERVMKRDNSTREQVLSRMKMQWND
EKRISLSNFVINNSNLKIAREEVGEILKILKIKQKQS

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=181, Percent_Identity=30.3867403314917, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI191252795, Length=181, Percent_Identity=30.3867403314917, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI110227607, Length=181, Percent_Identity=29.2817679558011, Blast_Score=67, Evalue=7e-12,
Organism=Homo sapiens, GI110227605, Length=181, Percent_Identity=29.2817679558011, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI110227603, Length=181, Percent_Identity=29.2817679558011, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI110227601, Length=181, Percent_Identity=29.2817679558011, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI205277394, Length=181, Percent_Identity=29.2817679558011, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI1786292, Length=177, Percent_Identity=32.2033898305085, Blast_Score=93, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17554944, Length=195, Percent_Identity=33.8461538461538, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI25143409, Length=171, Percent_Identity=34.5029239766082, Blast_Score=81, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6320402, Length=198, Percent_Identity=29.2929292929293, Blast_Score=89, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24644728, Length=178, Percent_Identity=33.1460674157303, Blast_Score=101, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24658602, Length=177, Percent_Identity=27.683615819209, Blast_Score=73, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 22627; Mature: 22496

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKIIGLTGGIGSGKTTIASFFKEEGVPVYIADDEAKKVMQSSEIINQIKTSFGESLFDN
CCEEEEECCCCCCCHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCC
NVLNRSKLAEIVFNNKEQLEKLNAIVHPAVKKDFQSWLLQNKGMDFVVYEAAILFESGKY
CCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHCCCCCC
KEFDYIVTVTAPEDVRIERVMKRDNSTREQVLSRMKMQWNDEKRISLSNFVINNSNLKIA
CCEEEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEEEHEEEECCCCEEH
REEVGEILKILKIKQKQS
HHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TKIIGLTGGIGSGKTTIASFFKEEGVPVYIADDEAKKVMQSSEIINQIKTSFGESLFDN
CEEEEECCCCCCCHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCC
NVLNRSKLAEIVFNNKEQLEKLNAIVHPAVKKDFQSWLLQNKGMDFVVYEAAILFESGKY
CCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHCCCCCC
KEFDYIVTVTAPEDVRIERVMKRDNSTREQVLSRMKMQWNDEKRISLSNFVINNSNLKIA
CCEEEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEEEHEEEECCCCEEH
REEVGEILKILKIKQKQS
HHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA