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The map label for this gene is rprX [H]

Identifier: 146301203

GI number: 146301203

Start: 4126897

End: 4128483

Strand: Reverse

Name: rprX [H]

Synonym: Fjoh_3461

Alternate gene names: 146301203

Gene position: 4128483-4126897 (Counterclockwise)

Preceding gene: 146301204

Following gene: 146301202

Centisome position: 67.71

GC content: 29.74

Gene sequence:

>1587_bases
ATGAATAAATTATTTTTTAGAATACTTGTTTTATTGATGAGTTTGTCCTTAATAGGGATAATTCTGGTACAGGTATTTTG
GTTCAATTCTTCATTTAAAAATAATGAAGAACAGTTTAAATACCACGTTACACAAGTAATTGGAAATGTTGCAGATAAAC
TTGAGCAGCAAGAAGAATACAGTTTTTACGACAAATACAACCGTATAAAAGACAGTACCGGTAAAATTCCACAAAAGGAA
GACTTACTTGAAGTATTGTATGTACAAAGAAACACAAAAACAAATAAAACAATTGTTTATTCTAATACTCTAAGCTCTGA
AGATTACGATATAGACGGATCTCTTTTTAATAAAAGATTCAGCAGCGAAAGATTTAAAAATTTCAGCTCTAAAAGAGTAA
CAGAAGTTTATAATAATAACAACGGAATTGATAATAATAGTTTAGGTCAAAGTATTATTCCGGATCTTAAAATTGAAAAA
TCCGGAAGTTTAGATATTTTAAATAAAGTTCAGCAGCAGATTCAGTATAAAGACATTGCTTCATTAACCCCCATTGAAGG
TCGAATTACAAAAGATAAACTGCATAAACTATTAAAAAAGGAATTAGAAGAATACGGTGTTAAAACCAAATTCGAATACG
GAATTTACAGCAGCGGTGTTCCAACCAAAATTAAATCGGATGGATTTCACTATGACAAAGAAGCAACATATAATATTCCG
ATATATACTGATAACGAAGGGAACAGCCGATATGAATTATCAGTTACCTTCCCAAATAAAAAGAAATTTTTATTATCTGA
GTTATTAAGTATTACTATTTTATCGATAGTATTTACATTAATTATAATAGTTGCTTACACAAGTGCATTAAATCAATTAC
TGCGTCAAAAACATATTTCTGAAATCAAAACAGATTTTATTAATAATATGACGCACGAGTTTAAAACACCAATTGCAACG
ATTAACTTAGCTCTAGATGCTATCAGGAGTCCTAAAGTAATTGAAGATAAAGAAAAAGTCTATCGATATCTTCAAATGAT
AAGGGATGAAAATAAAAGAATGCATGCCCAGGTTGAAAATGTACTCCGTATTTCTAAATTAGAAAAAAGAGAACTTGATA
TTACAAAAGAACCAACTGTAGTAACTGATATTATTGACGATGCAATCGAGCATGTAAATTTAATTTTAGAAGACAGAGAA
GGTACGGTTGTAAAACACTATAATGCAGCAAGAACAACGTGTTTGATTAATGAAGTGCATTTTACAAACGTATTAGTTAA
TATTTTAGAGAATGCTATAAAGTATTCGCCGGGAACACCCGAAATTGAAATATTTACAGAAAATGTAAAAGATATGATCC
TGATAAAAGTAAGAGATCATGGTTTAGGAATGAGTAAGATAGCTCAAAAACGAGTGTTTGAGAAATTTTACAGAGAACAT
ACAGGAGACCTTCATAATGTAAAAGGACACGGTTTAGGTCTTGCTTATGTAAAAAGAATTGTCGAGGATCACAATGGACA
AGTATATGTTGAAAGCGAAAAAGGAAAAGGTAGCACCTTTATAATAAAAATACCATTAATAAATTAA

Upstream 100 bases:

>100_bases
AAATTCTTAAAATTTTGAAAATAAAACAAAAACAGTCTTAAATGTTAATATTTGGTTAATGTATTATTTAGTATATTGTT
AAAATATTAATTTTGTTTCG

Downstream 100 bases:

>100_bases
AATATGGAAAATACTAACAAAAGAATACTTTTAGTAGAAGATGACCTAAATTTTGGGGCGGTTCTTAAAGATTATCTAAT
GTTAAATGACTTTGAAGTTA

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 528; Mature: 528

Protein sequence:

>528_residues
MNKLFFRILVLLMSLSLIGIILVQVFWFNSSFKNNEEQFKYHVTQVIGNVADKLEQQEEYSFYDKYNRIKDSTGKIPQKE
DLLEVLYVQRNTKTNKTIVYSNTLSSEDYDIDGSLFNKRFSSERFKNFSSKRVTEVYNNNNGIDNNSLGQSIIPDLKIEK
SGSLDILNKVQQQIQYKDIASLTPIEGRITKDKLHKLLKKELEEYGVKTKFEYGIYSSGVPTKIKSDGFHYDKEATYNIP
IYTDNEGNSRYELSVTFPNKKKFLLSELLSITILSIVFTLIIIVAYTSALNQLLRQKHISEIKTDFINNMTHEFKTPIAT
INLALDAIRSPKVIEDKEKVYRYLQMIRDENKRMHAQVENVLRISKLEKRELDITKEPTVVTDIIDDAIEHVNLILEDRE
GTVVKHYNAARTTCLINEVHFTNVLVNILENAIKYSPGTPEIEIFTENVKDMILIKVRDHGLGMSKIAQKRVFEKFYREH
TGDLHNVKGHGLGLAYVKRIVEDHNGQVYVESEKGKGSTFIIKIPLIN

Sequences:

>Translated_528_residues
MNKLFFRILVLLMSLSLIGIILVQVFWFNSSFKNNEEQFKYHVTQVIGNVADKLEQQEEYSFYDKYNRIKDSTGKIPQKE
DLLEVLYVQRNTKTNKTIVYSNTLSSEDYDIDGSLFNKRFSSERFKNFSSKRVTEVYNNNNGIDNNSLGQSIIPDLKIEK
SGSLDILNKVQQQIQYKDIASLTPIEGRITKDKLHKLLKKELEEYGVKTKFEYGIYSSGVPTKIKSDGFHYDKEATYNIP
IYTDNEGNSRYELSVTFPNKKKFLLSELLSITILSIVFTLIIIVAYTSALNQLLRQKHISEIKTDFINNMTHEFKTPIAT
INLALDAIRSPKVIEDKEKVYRYLQMIRDENKRMHAQVENVLRISKLEKRELDITKEPTVVTDIIDDAIEHVNLILEDRE
GTVVKHYNAARTTCLINEVHFTNVLVNILENAIKYSPGTPEIEIFTENVKDMILIKVRDHGLGMSKIAQKRVFEKFYREH
TGDLHNVKGHGLGLAYVKRIVEDHNGQVYVESEKGKGSTFIIKIPLIN
>Mature_528_residues
MNKLFFRILVLLMSLSLIGIILVQVFWFNSSFKNNEEQFKYHVTQVIGNVADKLEQQEEYSFYDKYNRIKDSTGKIPQKE
DLLEVLYVQRNTKTNKTIVYSNTLSSEDYDIDGSLFNKRFSSERFKNFSSKRVTEVYNNNNGIDNNSLGQSIIPDLKIEK
SGSLDILNKVQQQIQYKDIASLTPIEGRITKDKLHKLLKKELEEYGVKTKFEYGIYSSGVPTKIKSDGFHYDKEATYNIP
IYTDNEGNSRYELSVTFPNKKKFLLSELLSITILSIVFTLIIIVAYTSALNQLLRQKHISEIKTDFINNMTHEFKTPIAT
INLALDAIRSPKVIEDKEKVYRYLQMIRDENKRMHAQVENVLRISKLEKRELDITKEPTVVTDIIDDAIEHVNLILEDRE
GTVVKHYNAARTTCLINEVHFTNVLVNILENAIKYSPGTPEIEIFTENVKDMILIKVRDHGLGMSKIAQKRVFEKFYREH
TGDLHNVKGHGLGLAYVKRIVEDHNGQVYVESEKGKGSTFIIKIPLIN

Specific function: Member of the two-component regulatory system rprX/rprY. May activate rprY by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=231, Percent_Identity=25.5411255411255, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1790861, Length=203, Percent_Identity=29.064039408867, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1786783, Length=227, Percent_Identity=26.8722466960352, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1786600, Length=224, Percent_Identity=25.4464285714286, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI48994928, Length=234, Percent_Identity=26.0683760683761, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788713, Length=234, Percent_Identity=25.6410256410256, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1790346, Length=244, Percent_Identity=23.7704918032787, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1789149, Length=238, Percent_Identity=25.2100840336134, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1786912, Length=320, Percent_Identity=22.8125, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI87082128, Length=260, Percent_Identity=25.7692307692308, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788393, Length=226, Percent_Identity=22.5663716814159, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788549, Length=313, Percent_Identity=23.961661341853, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790551, Length=254, Percent_Identity=24.8031496062992, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 61001; Mature: 61001

Theoretical pI: Translated: 8.83; Mature: 8.83

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKLFFRILVLLMSLSLIGIILVQVFWFNSSFKNNEEQFKYHVTQVIGNVADKLEQQEEY
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SFYDKYNRIKDSTGKIPQKEDLLEVLYVQRNTKTNKTIVYSNTLSSEDYDIDGSLFNKRF
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCHHHHHHHH
SSERFKNFSSKRVTEVYNNNNGIDNNSLGQSIIPDLKIEKSGSLDILNKVQQQIQYKDIA
HHHHHHCCHHHHHHHHHCCCCCCCCCCCCHHHCCCCEECCCCCHHHHHHHHHHHHHHHHH
SLTPIEGRITKDKLHKLLKKELEEYGVKTKFEYGIYSSGVPTKIKSDGFHYDKEATYNIP
CCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEE
IYTDNEGNSRYELSVTFPNKKKFLLSELLSITILSIVFTLIIIVAYTSALNQLLRQKHIS
EEECCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIKTDFINNMTHEFKTPIATINLALDAIRSPKVIEDKEKVYRYLQMIRDENKRMHAQVEN
HHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHH
VLRISKLEKRELDITKEPTVVTDIIDDAIEHVNLILEDREGTVVKHYNAARTTCLINEVH
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHEEEECCCCCEEEECCCHHHHHEEHHHH
FTNVLVNILENAIKYSPGTPEIEIFTENVKDMILIKVRDHGLGMSKIAQKRVFEKFYREH
HHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHH
TGDLHNVKGHGLGLAYVKRIVEDHNGQVYVESEKGKGSTFIIKIPLIN
CCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEEECCC
>Mature Secondary Structure
MNKLFFRILVLLMSLSLIGIILVQVFWFNSSFKNNEEQFKYHVTQVIGNVADKLEQQEEY
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SFYDKYNRIKDSTGKIPQKEDLLEVLYVQRNTKTNKTIVYSNTLSSEDYDIDGSLFNKRF
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCHHHHHHHH
SSERFKNFSSKRVTEVYNNNNGIDNNSLGQSIIPDLKIEKSGSLDILNKVQQQIQYKDIA
HHHHHHCCHHHHHHHHHCCCCCCCCCCCCHHHCCCCEECCCCCHHHHHHHHHHHHHHHHH
SLTPIEGRITKDKLHKLLKKELEEYGVKTKFEYGIYSSGVPTKIKSDGFHYDKEATYNIP
CCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEE
IYTDNEGNSRYELSVTFPNKKKFLLSELLSITILSIVFTLIIIVAYTSALNQLLRQKHIS
EEECCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIKTDFINNMTHEFKTPIATINLALDAIRSPKVIEDKEKVYRYLQMIRDENKRMHAQVEN
HHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHH
VLRISKLEKRELDITKEPTVVTDIIDDAIEHVNLILEDREGTVVKHYNAARTTCLINEVH
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHEEEECCCCCEEEECCCHHHHHEEHHHH
FTNVLVNILENAIKYSPGTPEIEIFTENVKDMILIKVRDHGLGMSKIAQKRVFEKFYREH
HHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHH
TGDLHNVKGHGLGLAYVKRIVEDHNGQVYVESEKGKGSTFIIKIPLIN
CCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8469117 [H]