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The map label for this gene is ydcR [H]

Identifier: 146301138

GI number: 146301138

Start: 4058877

End: 4060298

Strand: Direct

Name: ydcR [H]

Synonym: Fjoh_3396

Alternate gene names: 146301138

Gene position: 4058877-4060298 (Clockwise)

Preceding gene: 146301135

Following gene: 146301146

Centisome position: 66.57

GC content: 38.47

Gene sequence:

>1422_bases
ATGGGAAACTCAAATTACTTATATCTACAGTTTGCAGACGTGATTGAAAAACAAATAAAATCAGGTCTTTTAAATGTTGG
CGATAAACTGCCGTCGATAAGAGAAGTCTGTGCAGAAACGGGTTATAGTATGAGTACAGTAAGCAAGGCTTATTATGAAG
TCGAAAGCCGTTCGCTGATTGAATCGCGCCCGCAGTCTGGTTATTATGTGAGTAATATTTCGGCACGAATCATTTCAGAA
CCTTCTGCCAGCACACCAATTTTAAGCGTCGAAAATATTGAACGCGAAGATTTAGTAGATTTGGTTTACGGCGATATGCG
CAAAAAAGACTTAACGATGCTTTCGCTTGGCTTTCCTTCAAATGAACTGTTACCAATAGCAAAGCTGAATAAAGGAATGG
TTCAGGCAATGCGCCAATTACCAAACAGCGGCACGAGTTATGAGGAAATTCAGGGAAACAGTAATTTAAGAAAAGAGATT
GCGCGCTGGTCTTTTACATGGGGAGGTTCCTTGACTGAAGAAGATATTATTACAACTCCAGGCTGTATTTCGGCTATTTC
AGATTGTTTATTGGCTTTGACAAAACCGGGAGACACAATTATTACCGAAAGTCCGGTATATTTTGGAATTCTGCAATTAG
CCAGATCTTTAGGTTTGTATGTAATGGAACTTCCTACTAATATGACAACGGGAATTGAACTTGAAGCTGTTAAAAAAACA
CTTTCGGCAAACAAAGTTAAAGCTTGTGTTTTGATGAGCAATTTCAGCAATCCGTCTGGAAGTATGATGCCGAATGAACA
CAAAAAAGAGATTGTCCGCTTGATGGATTTCTATAATGTTCCGTTAATTGAAGATGATATTCACGGCGATTTATATTTTG
GCTCAAGCCGACCGACTAACTGTAAAACCTATGACGAAAGTGGTATTGTACTTTGCTGCAGTTCGGTTTCTAAAACTCTG
GCACCGGGTTATCGTGTTGGATGGGTTTCTCCGGGAAAATTTAAAAAAGAAATTCTGAGAGCAAAATTATATCATACGAT
CTCCTCTCCTACTATTACGCATGAAGTGGTAGGCGATTTTTTAAAAAACGGACGTTATGAAAATCATCTTCGCAAAATTC
GCCAAATCCTGAACCGAAACTGCAATAATTACATCAATACAGTTTTAGAATCATTTCCGGCTGGTACAAAAGTAAGCCAG
CCTCAAGGCGGATTTTTCCTTTGGGTTGAACTGGATAAAAAAATCGACACTTCTGCTTTTTATCATTTGGCATTAAAACA
TAATATAAGCATTGCACCGGGAAGAATTTTTTCTTTTCAGGATCAATTCTCAAATTGTATGCGTTTGAGTTTTGGACTTC
CGTGGACGAATGAACTGCGTGAGTCTATTCGAACTTTAGGAAGACTGGCAAAAAGTATTTAG

Upstream 100 bases:

>100_bases
TCACGACAGTTTTTTGTTTTTTTGAAGAGACAAATTTCTAAAAAATAAAGTAGCAATACAGATACAGTTTTTGTAAATTG
CACCATAACAGTTTAATTTT

Downstream 100 bases:

>100_bases
AAAATACGTTTTATAAAAAAACCGGACAGTGCAACTACTCACCATCCGGCCAACAATTAATTAAAGAGACCAAAATTAAA
AAGTTATAAAACGAAATAAG

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 473; Mature: 472

Protein sequence:

>473_residues
MGNSNYLYLQFADVIEKQIKSGLLNVGDKLPSIREVCAETGYSMSTVSKAYYEVESRSLIESRPQSGYYVSNISARIISE
PSASTPILSVENIEREDLVDLVYGDMRKKDLTMLSLGFPSNELLPIAKLNKGMVQAMRQLPNSGTSYEEIQGNSNLRKEI
ARWSFTWGGSLTEEDIITTPGCISAISDCLLALTKPGDTIITESPVYFGILQLARSLGLYVMELPTNMTTGIELEAVKKT
LSANKVKACVLMSNFSNPSGSMMPNEHKKEIVRLMDFYNVPLIEDDIHGDLYFGSSRPTNCKTYDESGIVLCCSSVSKTL
APGYRVGWVSPGKFKKEILRAKLYHTISSPTITHEVVGDFLKNGRYENHLRKIRQILNRNCNNYINTVLESFPAGTKVSQ
PQGGFFLWVELDKKIDTSAFYHLALKHNISIAPGRIFSFQDQFSNCMRLSFGLPWTNELRESIRTLGRLAKSI

Sequences:

>Translated_473_residues
MGNSNYLYLQFADVIEKQIKSGLLNVGDKLPSIREVCAETGYSMSTVSKAYYEVESRSLIESRPQSGYYVSNISARIISE
PSASTPILSVENIEREDLVDLVYGDMRKKDLTMLSLGFPSNELLPIAKLNKGMVQAMRQLPNSGTSYEEIQGNSNLRKEI
ARWSFTWGGSLTEEDIITTPGCISAISDCLLALTKPGDTIITESPVYFGILQLARSLGLYVMELPTNMTTGIELEAVKKT
LSANKVKACVLMSNFSNPSGSMMPNEHKKEIVRLMDFYNVPLIEDDIHGDLYFGSSRPTNCKTYDESGIVLCCSSVSKTL
APGYRVGWVSPGKFKKEILRAKLYHTISSPTITHEVVGDFLKNGRYENHLRKIRQILNRNCNNYINTVLESFPAGTKVSQ
PQGGFFLWVELDKKIDTSAFYHLALKHNISIAPGRIFSFQDQFSNCMRLSFGLPWTNELRESIRTLGRLAKSI
>Mature_472_residues
GNSNYLYLQFADVIEKQIKSGLLNVGDKLPSIREVCAETGYSMSTVSKAYYEVESRSLIESRPQSGYYVSNISARIISEP
SASTPILSVENIEREDLVDLVYGDMRKKDLTMLSLGFPSNELLPIAKLNKGMVQAMRQLPNSGTSYEEIQGNSNLRKEIA
RWSFTWGGSLTEEDIITTPGCISAISDCLLALTKPGDTIITESPVYFGILQLARSLGLYVMELPTNMTTGIELEAVKKTL
SANKVKACVLMSNFSNPSGSMMPNEHKKEIVRLMDFYNVPLIEDDIHGDLYFGSSRPTNCKTYDESGIVLCCSSVSKTLA
PGYRVGWVSPGKFKKEILRAKLYHTISSPTITHEVVGDFLKNGRYENHLRKIRQILNRNCNNYINTVLESFPAGTKVSQP
QGGFFLWVELDKKIDTSAFYHLALKHNISIAPGRIFSFQDQFSNCMRLSFGLPWTNELRESIRTLGRLAKSI

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI4507369, Length=223, Percent_Identity=29.1479820627803, Blast_Score=93, Evalue=6e-19,
Organism=Homo sapiens, GI7705897, Length=314, Percent_Identity=22.9299363057325, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI33469970, Length=314, Percent_Identity=22.9299363057325, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI1787710, Length=470, Percent_Identity=35.9574468085106, Blast_Score=311, Evalue=6e-86,
Organism=Escherichia coli, GI1790797, Length=462, Percent_Identity=33.5497835497836, Blast_Score=300, Evalue=1e-82,
Organism=Caenorhabditis elegans, GI17567663, Length=352, Percent_Identity=22.4431818181818, Blast_Score=77, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6321000, Length=241, Percent_Identity=21.5767634854772, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI18859735, Length=229, Percent_Identity=25.764192139738, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21356535, Length=343, Percent_Identity=22.1574344023324, Blast_Score=69, Evalue=8e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 52882; Mature: 52751

Theoretical pI: Translated: 8.12; Mature: 8.12

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNSNYLYLQFADVIEKQIKSGLLNVGDKLPSIREVCAETGYSMSTVSKAYYEVESRSLI
CCCCCEEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
ESRPQSGYYVSNISARIISEPSASTPILSVENIEREDLVDLVYGDMRKKDLTMLSLGFPS
HCCCCCCEEEECCCEEEECCCCCCCCEEECCCCCHHHHHHHHHCCCCCCCCEEEEECCCC
NELLPIAKLNKGMVQAMRQLPNSGTSYEEIQGNSNLRKEIARWSFTWGGSLTEEDIITTP
CCCCCHHHHHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHEEECCCCCCCCCCCCCC
GCISAISDCLLALTKPGDTIITESPVYFGILQLARSLGLYVMELPTNMTTGIELEAVKKT
HHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHCEEEEEECCCCCCCCCHHHHHHH
LSANKVKACVLMSNFSNPSGSMMPNEHKKEIVRLMDFYNVPLIEDDIHGDLYFGSSRPTN
HHCCHHEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCEECCCCCCEEECCCCCCC
CKTYDESGIVLCCSSVSKTLAPGYRVGWVSPGKFKKEILRAKLYHTISSPTITHEVVGDF
CCEECCCCEEEEECHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
LKNGRYENHLRKIRQILNRNCNNYINTVLESFPAGTKVSQPQGGFFLWVELDKKIDTSAF
HHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCHHH
YHLALKHNISIAPGRIFSFQDQFSNCMRLSFGLPWTNELRESIRTLGRLAKSI
EEEEEECCCEECCCCEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GNSNYLYLQFADVIEKQIKSGLLNVGDKLPSIREVCAETGYSMSTVSKAYYEVESRSLI
CCCCEEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
ESRPQSGYYVSNISARIISEPSASTPILSVENIEREDLVDLVYGDMRKKDLTMLSLGFPS
HCCCCCCEEEECCCEEEECCCCCCCCEEECCCCCHHHHHHHHHCCCCCCCCEEEEECCCC
NELLPIAKLNKGMVQAMRQLPNSGTSYEEIQGNSNLRKEIARWSFTWGGSLTEEDIITTP
CCCCCHHHHHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHEEECCCCCCCCCCCCCC
GCISAISDCLLALTKPGDTIITESPVYFGILQLARSLGLYVMELPTNMTTGIELEAVKKT
HHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHCEEEEEECCCCCCCCCHHHHHHH
LSANKVKACVLMSNFSNPSGSMMPNEHKKEIVRLMDFYNVPLIEDDIHGDLYFGSSRPTN
HHCCHHEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCEECCCCCCEEECCCCCCC
CKTYDESGIVLCCSSVSKTLAPGYRVGWVSPGKFKKEILRAKLYHTISSPTITHEVVGDF
CCEECCCCEEEEECHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
LKNGRYENHLRKIRQILNRNCNNYINTVLESFPAGTKVSQPQGGFFLWVELDKKIDTSAF
HHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCHHH
YHLALKHNISIAPGRIFSFQDQFSNCMRLSFGLPWTNELRESIRTLGRLAKSI
EEEEEECCCEECCCCEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]