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The map label for this gene is sugE [H]

Identifier: 146301039

GI number: 146301039

Start: 3937766

End: 3938092

Strand: Direct

Name: sugE [H]

Synonym: Fjoh_3295

Alternate gene names: 146301039

Gene position: 3937766-3938092 (Clockwise)

Preceding gene: 146301038

Following gene: 146301040

Centisome position: 64.59

GC content: 38.53

Gene sequence:

>327_bases
ATGAACTGGATTATTTTAATTATTGCAGGCCTTTTTGAAGTAGCCTTTGCAACTTGCCTTGGAAAAGCAAAAGAAACCGC
AGGAATGGAAATGTATTATTGGTATATTGGTTTCTTTGCCTCTTTAACAATAAGTATGCTGCTGCTGATAAAAGCTACCG
AAACGCTCCCAATGGGAACTGCATACGCCGTATGGACAGGAATTGGTGCGGTTGGAACTGTGTTAATGGGAATATTTGTT
TTTAAAGAACCGGCAACTTTCTGGAGATTGTTTTTTCTTGTAACCTTAGTAAGTTCTATCGTAGGGCTTAAAGCGGTTTC
TCATTAA

Upstream 100 bases:

>100_bases
AAGCAGAATACGGGCTGAATTAAAATAAAATACTTTTTTATCATTTGTTAAATTTTTTCTGAATTGAGAGAAGGAACTTT
GCATCATAAATTTTAACTAT

Downstream 100 bases:

>100_bases
TAGAACATTTGCATTTTAATAAAAATCCATTTCATAAGAAATGGATTTTTTTTATGTCATAACTAATTACAAACATGGGA
ATTATATAAATATTAACTTA

Product: small multidrug resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 108; Mature: 108

Protein sequence:

>108_residues
MNWIILIIAGLFEVAFATCLGKAKETAGMEMYYWYIGFFASLTISMLLLIKATETLPMGTAYAVWTGIGAVGTVLMGIFV
FKEPATFWRLFFLVTLVSSIVGLKAVSH

Sequences:

>Translated_108_residues
MNWIILIIAGLFEVAFATCLGKAKETAGMEMYYWYIGFFASLTISMLLLIKATETLPMGTAYAVWTGIGAVGTVLMGIFV
FKEPATFWRLFFLVTLVSSIVGLKAVSH
>Mature_108_residues
MNWIILIIAGLFEVAFATCLGKAKETAGMEMYYWYIGFFASLTISMLLLIKATETLPMGTAYAVWTGIGAVGTVLMGIFV
FKEPATFWRLFFLVTLVSSIVGLKAVSH

Specific function: Quaternary ammonium compound efflux pump. Confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. SugE (TC 2.A.7.1.4) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082378, Length=108, Percent_Identity=46.2962962962963, Blast_Score=79, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 11883; Mature: 11883

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNWIILIIAGLFEVAFATCLGKAKETAGMEMYYWYIGFFASLTISMLLLIKATETLPMGT
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
AYAVWTGIGAVGTVLMGIFVFKEPATFWRLFFLVTLVSSIVGLKAVSH
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNWIILIIAGLFEVAFATCLGKAKETAGMEMYYWYIGFFASLTISMLLLIKATETLPMGT
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
AYAVWTGIGAVGTVLMGIFVFKEPATFWRLFFLVTLVSSIVGLKAVSH
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12644504; 11677608 [H]