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The map label for this gene is mqo

Identifier: 146300284

GI number: 146300284

Start: 3011368

End: 3012861

Strand: Direct

Name: mqo

Synonym: Fjoh_2529

Alternate gene names: 146300284

Gene position: 3011368-3012861 (Clockwise)

Preceding gene: 146300283

Following gene: 146300285

Centisome position: 49.39

GC content: 37.08

Gene sequence:

>1494_bases
ATGCCTGACAATACAATACGTTCCAATAGTGAAGTAGTGCTTATTGGAGCTGGAATTATGAGTGCAACTCTTGGATTAAT
TTTAAAAGAGCTGCAGCCGGATATAAAAATTGAAATTTACGAAAGATTAGATGTGGCGGCTGCCGAAAGCTCGGATGCCT
GGAATAATGCAGGAACCGGACACTCAGCTTTTTGTGAATTAAATTATACTCCAGAAAAGGCTGATGGAAGTATTGACCCT
AAAAAAGCAATCAGTATTGCTGAATCATTTGAAATTTCACGACAGTTTTGGTCGTATTTAGTACAGCAGAATAAAGTTCC
ATCTCCGGAAAATTTTATAAAAAGTGTTCCTCACATGAGTTTTGTATGGGGAGACAAAAATGTAGAATATTTAAGAAAAA
GATTCGAAGCACTTCAAAGTAACCCAATTTTTGCAGATATGACATTCAGTACTGATTTTAATCAGTTAAAAGAATGGATG
CCTCTTGTAATGGAAGGAAGAGAAGCAGATGAAAAATTAGCTGCAACTCACATGGAAATAGGTACCGATGTTAATTTTGG
AGCCTTAACAAGAAGCATGTTTAATTATCTTGAAAAGTTAGACGGCGTTACTTTATACTTTAATCACGAAGTTAAAAAGT
TAAAACAGCGTGAAGATAAATCATGGAGAATTAAAATTACAGATTTGTCGACAGGACAAAAACGCAAAGCATATACAAAA
TTTGTATTTATTGGTGCTGGCGGCGGTTCATTGCCATTATTAGAAAAAGCAGATGTTCCGGAAGGTCACGGTTACGGCGG
TTTCCCAGTTAGCGGACAATGGCTGAAATGTACTAATCCGGAAGTTATTGCAAAACACCAGGCAAAAGTTTATGGTAAAG
CTAGTGTTGGAGCACCTCCAATGTCAGTTCCTCATATTGATACACGTGTAATCGATGGTGAAAAAGCACTTCTTTTTGGC
CCTTTCGCCGGATTCTCAACACGTTTCTTAAAAAATGGTTCATATCTAGATTTACCTCTATCTATAAAAGCAAACAATTT
AATCCCAATGCTTTCTGCGGGATTCCATAATATTCCATTAACGAAATATTTAATCGAGCAGGTTCGTCAGTCTCCAAAAG
ACAGAATGAAAGCACTTCGTGAATATTTGCCTACTGCACGCTCTAAAGACTGGAAATTAGAAAAAGCAGGTCAGCGTGTT
CAGGTTATTAAAAAAGGAAAAGATGGCGGCGGTGTTTTAGAATTTGGTACAGAAGTAATCAATACACACGACGGAACTCT
GGCAGTTTTATTAGGAGCTTCTCCGGGAGCATCAACTGCAGTAGCTATTATGGTTGACTTAATCAGCAGATGTTTTACCA
ATCAGATTAAAACTCCTGAGTGGGAAGCTAAAATGAAAGAAATGATTCCTTCTTACGGTAAAACTCTGAACGACAAACCA
GAGCTTTTAGCAGAAATGAGAAAACATACGGCTGAAGTTTTAAAAATTAAATAA

Upstream 100 bases:

>100_bases
TTTAGAAAAAATTATAGTTTCCTAACTTTTATCATGCAAAAATTAGTTTTTTTTTGCGATTGAAAGAAGTACCTTTGCAC
TTTAAAAACAAAATACTGTT

Downstream 100 bases:

>100_bases
TTAAAATTTCGAAATGTAAATAATACCCAAGGACTTAGTTTGTAAATAACTGAGTCCTTTTTTAATTTTAACCAAAAAGA
ATATGGCACTTTCAAAAACA

Product: malate:quinone oxidoreductase

Products: NA

Alternate protein names: MQO; Malate dehydrogenase [quinone]

Number of amino acids: Translated: 497; Mature: 496

Protein sequence:

>497_residues
MPDNTIRSNSEVVLIGAGIMSATLGLILKELQPDIKIEIYERLDVAAAESSDAWNNAGTGHSAFCELNYTPEKADGSIDP
KKAISIAESFEISRQFWSYLVQQNKVPSPENFIKSVPHMSFVWGDKNVEYLRKRFEALQSNPIFADMTFSTDFNQLKEWM
PLVMEGREADEKLAATHMEIGTDVNFGALTRSMFNYLEKLDGVTLYFNHEVKKLKQREDKSWRIKITDLSTGQKRKAYTK
FVFIGAGGGSLPLLEKADVPEGHGYGGFPVSGQWLKCTNPEVIAKHQAKVYGKASVGAPPMSVPHIDTRVIDGEKALLFG
PFAGFSTRFLKNGSYLDLPLSIKANNLIPMLSAGFHNIPLTKYLIEQVRQSPKDRMKALREYLPTARSKDWKLEKAGQRV
QVIKKGKDGGGVLEFGTEVINTHDGTLAVLLGASPGASTAVAIMVDLISRCFTNQIKTPEWEAKMKEMIPSYGKTLNDKP
ELLAEMRKHTAEVLKIK

Sequences:

>Translated_497_residues
MPDNTIRSNSEVVLIGAGIMSATLGLILKELQPDIKIEIYERLDVAAAESSDAWNNAGTGHSAFCELNYTPEKADGSIDP
KKAISIAESFEISRQFWSYLVQQNKVPSPENFIKSVPHMSFVWGDKNVEYLRKRFEALQSNPIFADMTFSTDFNQLKEWM
PLVMEGREADEKLAATHMEIGTDVNFGALTRSMFNYLEKLDGVTLYFNHEVKKLKQREDKSWRIKITDLSTGQKRKAYTK
FVFIGAGGGSLPLLEKADVPEGHGYGGFPVSGQWLKCTNPEVIAKHQAKVYGKASVGAPPMSVPHIDTRVIDGEKALLFG
PFAGFSTRFLKNGSYLDLPLSIKANNLIPMLSAGFHNIPLTKYLIEQVRQSPKDRMKALREYLPTARSKDWKLEKAGQRV
QVIKKGKDGGGVLEFGTEVINTHDGTLAVLLGASPGASTAVAIMVDLISRCFTNQIKTPEWEAKMKEMIPSYGKTLNDKP
ELLAEMRKHTAEVLKIK
>Mature_496_residues
PDNTIRSNSEVVLIGAGIMSATLGLILKELQPDIKIEIYERLDVAAAESSDAWNNAGTGHSAFCELNYTPEKADGSIDPK
KAISIAESFEISRQFWSYLVQQNKVPSPENFIKSVPHMSFVWGDKNVEYLRKRFEALQSNPIFADMTFSTDFNQLKEWMP
LVMEGREADEKLAATHMEIGTDVNFGALTRSMFNYLEKLDGVTLYFNHEVKKLKQREDKSWRIKITDLSTGQKRKAYTKF
VFIGAGGGSLPLLEKADVPEGHGYGGFPVSGQWLKCTNPEVIAKHQAKVYGKASVGAPPMSVPHIDTRVIDGEKALLFGP
FAGFSTRFLKNGSYLDLPLSIKANNLIPMLSAGFHNIPLTKYLIEQVRQSPKDRMKALREYLPTARSKDWKLEKAGQRVQ
VIKKGKDGGGVLEFGTEVINTHDGTLAVLLGASPGASTAVAIMVDLISRCFTNQIKTPEWEAKMKEMIPSYGKTLNDKPE
LLAEMRKHTAEVLKIK

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0579

COG function: function code R; Predicted dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MQO family

Homologues:

Organism=Escherichia coli, GI1788539, Length=487, Percent_Identity=52.7720739219713, Blast_Score=560, Evalue=1e-161,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MQO_FLAJ1 (A5FGX2)

Other databases:

- EMBL:   CP000685
- RefSeq:   YP_001194875.1
- STRING:   A5FGX2
- GeneID:   5091983
- GenomeReviews:   CP000685_GR
- KEGG:   fjo:Fjoh_2529
- eggNOG:   COG0579
- HOGENOM:   HBG289663
- OMA:   NALKEYF
- ProtClustDB:   PRK05257
- BioCyc:   FJOH376686:FJOH_2529-MONOMER
- HAMAP:   MF_00212
- InterPro:   IPR006231
- TIGRFAMs:   TIGR01320

Pfam domain/function: PF06039 Mqo

EC number: =1.1.5.4

Molecular weight: Translated: 55293; Mature: 55162

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDNTIRSNSEVVLIGAGIMSATLGLILKELQPDIKIEIYERLDVAAAESSDAWNNAGTG
CCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCEEEEEHHHHHHHCCCCCCCCCCCCC
HSAFCELNYTPEKADGSIDPKKAISIAESFEISRQFWSYLVQQNKVPSPENFIKSVPHMS
CCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCE
FVWGDKNVEYLRKRFEALQSNPIFADMTFSTDFNQLKEWMPLVMEGREADEKLAATHMEI
EEECCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHC
GTDVNFGALTRSMFNYLEKLDGVTLYFNHEVKKLKQREDKSWRIKITDLSTGQKRKAYTK
CCCCCHHHHHHHHHHHHHHHCCEEEEECHHHHHHHHCCCCCEEEEEEECCCCCCCCEEEE
FVFIGAGGGSLPLLEKADVPEGHGYGGFPVSGQWLKCTNPEVIAKHQAKVYGKASVGAPP
EEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHEEECCCCCCCC
MSVPHIDTRVIDGEKALLFGPFAGFSTRFLKNGSYLDLPLSIKANNLIPMLSAGFHNIPL
CCCCCCCEEEECCCCEEEEECCCCCHHHHHCCCCEEEEEEEEECCCCCHHHHCCCCCCCH
TKYLIEQVRQSPKDRMKALREYLPTARSKDWKLEKAGQRVQVIKKGKDGGGVLEFGTEVI
HHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCHHHCCCEEEHHCCCCCCCCCHHHCHHHH
NTHDGTLAVLLGASPGASTAVAIMVDLISRCFTNQIKTPEWEAKMKEMIPSYGKTLNDKP
CCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCH
ELLAEMRKHTAEVLKIK
HHHHHHHHHHHHHEECC
>Mature Secondary Structure 
PDNTIRSNSEVVLIGAGIMSATLGLILKELQPDIKIEIYERLDVAAAESSDAWNNAGTG
CCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCEEEEEHHHHHHHCCCCCCCCCCCCC
HSAFCELNYTPEKADGSIDPKKAISIAESFEISRQFWSYLVQQNKVPSPENFIKSVPHMS
CCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCE
FVWGDKNVEYLRKRFEALQSNPIFADMTFSTDFNQLKEWMPLVMEGREADEKLAATHMEI
EEECCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHC
GTDVNFGALTRSMFNYLEKLDGVTLYFNHEVKKLKQREDKSWRIKITDLSTGQKRKAYTK
CCCCCHHHHHHHHHHHHHHHCCEEEEECHHHHHHHHCCCCCEEEEEEECCCCCCCCEEEE
FVFIGAGGGSLPLLEKADVPEGHGYGGFPVSGQWLKCTNPEVIAKHQAKVYGKASVGAPP
EEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHEEECCCCCCCC
MSVPHIDTRVIDGEKALLFGPFAGFSTRFLKNGSYLDLPLSIKANNLIPMLSAGFHNIPL
CCCCCCCEEEECCCCEEEEECCCCCHHHHHCCCCEEEEEEEEECCCCCHHHHCCCCCCCH
TKYLIEQVRQSPKDRMKALREYLPTARSKDWKLEKAGQRVQVIKKGKDGGGVLEFGTEVI
HHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCHHHCCCEEEHHCCCCCCCCCHHHCHHHH
NTHDGTLAVLLGASPGASTAVAIMVDLISRCFTNQIKTPEWEAKMKEMIPSYGKTLNDKP
CCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCH
ELLAEMRKHTAEVLKIK
HHHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA