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The map label for this gene is kdpD [H]

Identifier: 146300256

GI number: 146300256

Start: 2988419

End: 2989471

Strand: Direct

Name: kdpD [H]

Synonym: Fjoh_2501

Alternate gene names: 146300256

Gene position: 2988419-2989471 (Clockwise)

Preceding gene: 146300252

Following gene: 146300261

Centisome position: 49.02

GC content: 30.96

Gene sequence:

>1053_bases
ATGAAATTATATCATAACCTTTCGCAAATTAGCTTTTTGAAAAAAAGTTATGCGTTTAAATTTTTGTTTGTTGCTTTTAT
AGGAATACATATTCCGTTAATAGGAATCCTTTTTTTTGTCCTTTTTTTTGAGCACACTATTTCTCCTGCATCAATCTTGT
TTTTTTCATTAATAATGACATTGCTGGCGACAGCAATAACTCTAATGGTTTTAAAACAGCTTATTAAACCCATTTCTATT
GCATCAAAATCTTTAGACGATTACAGAAACAGCCGTAAATTGTCTATACTTCCAACCGAATATACCGATGAAGCAGGTTT
GCTGATGTGCAACATTCAGGAATCGATTTATGAGTCTGAGAGTTTTATAAATGAAAAGCAGGATTTGATTTATATGCTTT
CGCATGATTTGAAAAATTTTGCCGGAAATCCGCAGGGACTGGCGAAACTAATTTTAAGTGAAAATCCATCTGAATCTGTA
AAACATTTAGCCGATTTAATTTGCGAATCGACTAATTTACAGTTTCGTTACATCGAAAACTTCATAAAATTATTAAAAGA
GCAGGATCAGATTTCAAAAATAACATCTGAATCCAGAATCATTAATTTCCAAAATATTCTGCCTCTTATAAATGAGCAGG
TCGAACAGCGTTTATTAGACAAAAACATAATACTTAATTTAAGTCTTGAAATAGATGAAGCTAAACTTAGAATAGATGAA
GGTCTCTTAGTTCAGGTGATTGTGAATTTGATTAGCAATGCTGTAAAATTCTCTTATTTTGACAGTGTAATTAAAGTCAG
AATTTATAAAGAACAATCAGATTTGATTATAACAGTTGCCGACAGGGGAATTGGTTTTGATAAACATCAAATAGAAGAGT
TATTTAAGAAGTTTACCAAAATGAGCCGATTGGGAACTGCGAATGAATCATCAACTGGAATTGGACTTTATTTATGTAAA
AAAATTATCGAAAAAAATAAAGGCCGATTAAGTGCTTTAAGCGAAGGTAAAAATAAAGGCGCCGAGTTTAAAATTGAGTT
CGATATCAATTAA

Upstream 100 bases:

>100_bases
AATTATGTAATTTGCTAGTTTAATTAACTTTAAAAGTTAACTTTGTTTCTGCTATTGAGCCCCAAGCTGCAGTATATAAC
CTATAGTTTTGTTATGTTTT

Downstream 100 bases:

>100_bases
AAAAAATAAGGTCATTAAGATTTTCACTCTTAATGACCTTATTTTTTGCAGGAAATTGAATTAAGCAATAATTCGTTTAT
AAGGGATTTTGAAAAACAAG

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MKLYHNLSQISFLKKSYAFKFLFVAFIGIHIPLIGILFFVLFFEHTISPASILFFSLIMTLLATAITLMVLKQLIKPISI
ASKSLDDYRNSRKLSILPTEYTDEAGLLMCNIQESIYESESFINEKQDLIYMLSHDLKNFAGNPQGLAKLILSENPSESV
KHLADLICESTNLQFRYIENFIKLLKEQDQISKITSESRIINFQNILPLINEQVEQRLLDKNIILNLSLEIDEAKLRIDE
GLLVQVIVNLISNAVKFSYFDSVIKVRIYKEQSDLIITVADRGIGFDKHQIEELFKKFTKMSRLGTANESSTGIGLYLCK
KIIEKNKGRLSALSEGKNKGAEFKIEFDIN

Sequences:

>Translated_350_residues
MKLYHNLSQISFLKKSYAFKFLFVAFIGIHIPLIGILFFVLFFEHTISPASILFFSLIMTLLATAITLMVLKQLIKPISI
ASKSLDDYRNSRKLSILPTEYTDEAGLLMCNIQESIYESESFINEKQDLIYMLSHDLKNFAGNPQGLAKLILSENPSESV
KHLADLICESTNLQFRYIENFIKLLKEQDQISKITSESRIINFQNILPLINEQVEQRLLDKNIILNLSLEIDEAKLRIDE
GLLVQVIVNLISNAVKFSYFDSVIKVRIYKEQSDLIITVADRGIGFDKHQIEELFKKFTKMSRLGTANESSTGIGLYLCK
KIIEKNKGRLSALSEGKNKGAEFKIEFDIN
>Mature_350_residues
MKLYHNLSQISFLKKSYAFKFLFVAFIGIHIPLIGILFFVLFFEHTISPASILFFSLIMTLLATAITLMVLKQLIKPISI
ASKSLDDYRNSRKLSILPTEYTDEAGLLMCNIQESIYESESFINEKQDLIYMLSHDLKNFAGNPQGLAKLILSENPSESV
KHLADLICESTNLQFRYIENFIKLLKEQDQISKITSESRIINFQNILPLINEQVEQRLLDKNIILNLSLEIDEAKLRIDE
GLLVQVIVNLISNAVKFSYFDSVIKVRIYKEQSDLIITVADRGIGFDKHQIEELFKKFTKMSRLGTANESSTGIGLYLCK
KIIEKNKGRLSALSEGKNKGAEFKIEFDIN

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon. KdpD may function as a membrane-associated protein kinase that phosphorylates kdpE in response to environmental signals [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=219, Percent_Identity=23.2876712328767, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI145693157, Length=258, Percent_Identity=26.3565891472868, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR014729
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR003852
- InterPro:   IPR006016 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF02702 KdpD; PF00582 Usp [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 39978; Mature: 39978

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLYHNLSQISFLKKSYAFKFLFVAFIGIHIPLIGILFFVLFFEHTISPASILFFSLIMT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LLATAITLMVLKQLIKPISIASKSLDDYRNSRKLSILPTEYTDEAGLLMCNIQESIYESE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEECHHHHHHHH
SFINEKQDLIYMLSHDLKNFAGNPQGLAKLILSENPSESVKHLADLICESTNLQFRYIEN
HHHCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHH
FIKLLKEQDQISKITSESRIINFQNILPLINEQVEQRLLDKNIILNLSLEIDEAKLRIDE
HHHHHHHHHHHHHHHHHHHEECHHHHHHHHHHHHHHHHHCCCEEEEEEEEECHHHHHHCC
GLLVQVIVNLISNAVKFSYFDSVIKVRIYKEQSDLIITVADRGIGFDKHQIEELFKKFTK
CHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHH
MSRLGTANESSTGIGLYLCKKIIEKNKGRLSALSEGKNKGAEFKIEFDIN
HHHCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHCCCCCCCEEEEEEECC
>Mature Secondary Structure
MKLYHNLSQISFLKKSYAFKFLFVAFIGIHIPLIGILFFVLFFEHTISPASILFFSLIMT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LLATAITLMVLKQLIKPISIASKSLDDYRNSRKLSILPTEYTDEAGLLMCNIQESIYESE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEECHHHHHHHH
SFINEKQDLIYMLSHDLKNFAGNPQGLAKLILSENPSESVKHLADLICESTNLQFRYIEN
HHHCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHH
FIKLLKEQDQISKITSESRIINFQNILPLINEQVEQRLLDKNIILNLSLEIDEAKLRIDE
HHHHHHHHHHHHHHHHHHHEECHHHHHHHHHHHHHHHHHCCCEEEEEEEEECHHHHHHCC
GLLVQVIVNLISNAVKFSYFDSVIKVRIYKEQSDLIITVADRGIGFDKHQIEELFKKFTK
CHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHH
MSRLGTANESSTGIGLYLCKKIIEKNKGRLSALSEGKNKGAEFKIEFDIN
HHHCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9226259; 11466286 [H]