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The map label for this gene is engD [H]

Identifier: 146300222

GI number: 146300222

Start: 2953954

End: 2955048

Strand: Direct

Name: engD [H]

Synonym: Fjoh_2467

Alternate gene names: 146300222

Gene position: 2953954-2955048 (Clockwise)

Preceding gene: 146300220

Following gene: 146300223

Centisome position: 48.45

GC content: 36.16

Gene sequence:

>1095_bases
ATGAAAGCAGGAATTGTAGGATTGCCAAATGTTGGAAAATCAACATTATTTAATTGTTTATCTAATGCAAAAGCGCAGAG
TGCGAACTTTCCATTTTGTACTATCGAACCTAATATTGGTGTTGTAAACGTTCCAGATCCAAGAATCAACAAGTTAGAGG
AATTGGTAAAACCAGAACGCGTTCAAATGGCAACTGTAGATATCGTAGATATTGCAGGTTTGGTAAAAGGAGCAAGTAAA
GGAGAAGGTCTTGGAAACCAGTTTTTAGGAAACATTAGAGAGTGTAATGCTATCATTCACGTTTTACGTTGTTTTGATAA
TGACAATATTGTACACGTTGACGGAAACGTAAACCCAATTCGTGACAAAGAAACAATTGATATCGAATTGCAGTTAAAAG
ATTTAGAAACAGTCGAAAAACGTTTAGAAAAAGTAAAACGTGCTGCAAAAACCGGAAATAAAGAAGCTCAGGCAGAAGAA
GCATTATTAAACAGAATTAGAGAAGCTCTTTTACAGGCAAAATCTGCAAGAACAATTGTTCCTCAAAACAATGATGAAGA
AGTTCTTATGGAAGCTTTCCAATTAATTACAGCAAAACCAGTTTTATACGTTTGTAACGTTGACGAAAGCTCTGCTGTAA
ACGGAAACAAATATGTTGATCAGGTTCGTGAATTAGTAAAAGATGAAGAAGCTGAAGTGATTGTACTTTCAGTAGGAGCA
GAAGCTGATATTACAGAATTAGAAAGCTATGAAGAGCGTCAGGTTTTCCTTGAAGATATGGGATTAGAAGAGCCGGGAGC
ATCTGTTCTAATTCGTGCAGCTTATAAATTATTGAAACAGCAGACTTACTTTACTGCTGGTGTAAAAGAAGTTCGTGCCT
GGACAATCAATATTGGAGCTACAGCACCGCAAGCAGCTGGAGTTATCCATACAGATTTTGAAAAAGGTTTCATCCGTGCA
GAGGTAATTTCATACGATGATTATGTTCAGTATGGTTCTGAGGCAAAAGCAAAAGAAGCTGGAAAATTCAGAGTTGAAGG
AAAAGAATATATCGTGAAAGATGGTGATGTAATGCATTTCCGTTTTAATGTTTAA

Upstream 100 bases:

>100_bases
GAAACGAAAAATAAAAACGTAAATCATAAATCATTACAATACAATTGTTAATGACCAGACCTGATAGTTCAGTGTCGAAT
AAAATAAACAGAAACAAGAA

Downstream 100 bases:

>100_bases
TCTTTTTTAGAGAGAAGAAGAAAGAACAAAGAGAATAGACTAAAACTGCTGGAGGAATTCAGCAGTTTTTTTTGTTTTTA
TTATTTAGGTTTTTATTGTC

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MKAGIVGLPNVGKSTLFNCLSNAKAQSANFPFCTIEPNIGVVNVPDPRINKLEELVKPERVQMATVDIVDIAGLVKGASK
GEGLGNQFLGNIRECNAIIHVLRCFDNDNIVHVDGNVNPIRDKETIDIELQLKDLETVEKRLEKVKRAAKTGNKEAQAEE
ALLNRIREALLQAKSARTIVPQNNDEEVLMEAFQLITAKPVLYVCNVDESSAVNGNKYVDQVRELVKDEEAEVIVLSVGA
EADITELESYEERQVFLEDMGLEEPGASVLIRAAYKLLKQQTYFTAGVKEVRAWTINIGATAPQAAGVIHTDFEKGFIRA
EVISYDDYVQYGSEAKAKEAGKFRVEGKEYIVKDGDVMHFRFNV

Sequences:

>Translated_364_residues
MKAGIVGLPNVGKSTLFNCLSNAKAQSANFPFCTIEPNIGVVNVPDPRINKLEELVKPERVQMATVDIVDIAGLVKGASK
GEGLGNQFLGNIRECNAIIHVLRCFDNDNIVHVDGNVNPIRDKETIDIELQLKDLETVEKRLEKVKRAAKTGNKEAQAEE
ALLNRIREALLQAKSARTIVPQNNDEEVLMEAFQLITAKPVLYVCNVDESSAVNGNKYVDQVRELVKDEEAEVIVLSVGA
EADITELESYEERQVFLEDMGLEEPGASVLIRAAYKLLKQQTYFTAGVKEVRAWTINIGATAPQAAGVIHTDFEKGFIRA
EVISYDDYVQYGSEAKAKEAGKFRVEGKEYIVKDGDVMHFRFNV
>Mature_364_residues
MKAGIVGLPNVGKSTLFNCLSNAKAQSANFPFCTIEPNIGVVNVPDPRINKLEELVKPERVQMATVDIVDIAGLVKGASK
GEGLGNQFLGNIRECNAIIHVLRCFDNDNIVHVDGNVNPIRDKETIDIELQLKDLETVEKRLEKVKRAAKTGNKEAQAEE
ALLNRIREALLQAKSARTIVPQNNDEEVLMEAFQLITAKPVLYVCNVDESSAVNGNKYVDQVRELVKDEEAEVIVLSVGA
EADITELESYEERQVFLEDMGLEEPGASVLIRAAYKLLKQQTYFTAGVKEVRAWTINIGATAPQAAGVIHTDFEKGFIRA
EVISYDDYVQYGSEAKAKEAGKFRVEGKEYIVKDGDVMHFRFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=369, Percent_Identity=44.9864498644986, Blast_Score=313, Evalue=2e-85,
Organism=Homo sapiens, GI58761502, Length=228, Percent_Identity=39.9122807017544, Blast_Score=158, Evalue=6e-39,
Organism=Homo sapiens, GI24308117, Length=190, Percent_Identity=27.3684210526316, Blast_Score=75, Evalue=8e-14,
Organism=Escherichia coli, GI1787454, Length=364, Percent_Identity=58.7912087912088, Blast_Score=427, Evalue=1e-121,
Organism=Escherichia coli, GI1789574, Length=141, Percent_Identity=32.6241134751773, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17509631, Length=366, Percent_Identity=41.8032786885246, Blast_Score=298, Evalue=3e-81,
Organism=Caenorhabditis elegans, GI17508313, Length=100, Percent_Identity=36, Blast_Score=71, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6319499, Length=373, Percent_Identity=39.6782841823056, Blast_Score=244, Evalue=1e-65,
Organism=Saccharomyces cerevisiae, GI6321773, Length=379, Percent_Identity=36.1477572559367, Blast_Score=213, Evalue=3e-56,
Organism=Saccharomyces cerevisiae, GI6321649, Length=158, Percent_Identity=36.0759493670886, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6321962, Length=137, Percent_Identity=30.6569343065693, Blast_Score=69, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24640873, Length=367, Percent_Identity=42.5068119891008, Blast_Score=295, Evalue=3e-80,
Organism=Drosophila melanogaster, GI24640877, Length=367, Percent_Identity=42.5068119891008, Blast_Score=295, Evalue=3e-80,
Organism=Drosophila melanogaster, GI24640875, Length=367, Percent_Identity=42.5068119891008, Blast_Score=295, Evalue=3e-80,
Organism=Drosophila melanogaster, GI24640879, Length=326, Percent_Identity=40.4907975460123, Blast_Score=241, Evalue=6e-64,
Organism=Drosophila melanogaster, GI20129375, Length=181, Percent_Identity=29.2817679558011, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24585318, Length=102, Percent_Identity=34.3137254901961, Blast_Score=72, Evalue=8e-13,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 40298; Mature: 40298

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAGIVGLPNVGKSTLFNCLSNAKAQSANFPFCTIEPNIGVVNVPDPRINKLEELVKPER
CCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEECCCCCEEECCCCHHHHHHHHHCCCC
VQMATVDIVDIAGLVKGASKGEGLGNQFLGNIRECNAIIHVLRCFDNDNIVHVDGNVNPI
EEEEEEHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCC
RDKETIDIELQLKDLETVEKRLEKVKRAAKTGNKEAQAEEALLNRIREALLQAKSARTIV
CCCCEEEEEEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEC
PQNNDEEVLMEAFQLITAKPVLYVCNVDESSAVNGNKYVDQVRELVKDEEAEVIVLSVGA
CCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECC
EADITELESYEERQVFLEDMGLEEPGASVLIRAAYKLLKQQTYFTAGVKEVRAWTINIGA
CCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHEEEEEEEEECC
TAPQAAGVIHTDFEKGFIRAEVISYDDYVQYGSEAKAKEAGKFRVEGKEYIVKDGDVMHF
CCCCCCCCEEECCCCCCEEEEEECCHHHHHCCCCCCHHCCCCEEECCCEEEEECCCEEEE
RFNV
EECC
>Mature Secondary Structure
MKAGIVGLPNVGKSTLFNCLSNAKAQSANFPFCTIEPNIGVVNVPDPRINKLEELVKPER
CCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEECCCCCEEECCCCHHHHHHHHHCCCC
VQMATVDIVDIAGLVKGASKGEGLGNQFLGNIRECNAIIHVLRCFDNDNIVHVDGNVNPI
EEEEEEHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCC
RDKETIDIELQLKDLETVEKRLEKVKRAAKTGNKEAQAEEALLNRIREALLQAKSARTIV
CCCCEEEEEEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEC
PQNNDEEVLMEAFQLITAKPVLYVCNVDESSAVNGNKYVDQVRELVKDEEAEVIVLSVGA
CCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECC
EADITELESYEERQVFLEDMGLEEPGASVLIRAAYKLLKQQTYFTAGVKEVRAWTINIGA
CCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHEEEEEEEEECC
TAPQAAGVIHTDFEKGFIRAEVISYDDYVQYGSEAKAKEAGKFRVEGKEYIVKDGDVMHF
CCCCCCCCEEECCCCCCEEEEEECCHHHHHCCCCCCHHCCCCEEECCCEEEEECCCEEEE
RFNV
EECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA