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The map label for this gene is yhdY [H]

Identifier: 146300182

GI number: 146300182

Start: 2904131

End: 2905783

Strand: Direct

Name: yhdY [H]

Synonym: Fjoh_2427

Alternate gene names: 146300182

Gene position: 2904131-2905783 (Clockwise)

Preceding gene: 146300181

Following gene: 146300183

Centisome position: 47.63

GC content: 30.85

Gene sequence:

>1653_bases
ATGAAAAATAAATTACTTTGGTTTTTAGCTGTTTTCACTGTTTCGTTTTATTGGGCTTCATTTGCTCAAAAGAGCAATCA
CGATACTTTACATAAAATTGAAGTTAAGCCCAAATTAAAACCATATCCGGTTGCTCCATTTAAGGATACACTTTTCTTTA
TCTACAATAAAGTTGGTTCATTTTCTGCCGAAAACCGGGCACATGCCATTACAGAAAAAATTAGAAAGCTTTATGAAGAT
TCTTTTTTCGAACAAGATTCTATTTTAGTCGTTCCTTCAGATCTGTCACAAGATATTATTTATAAAAATGATTTTATTAT
CATGTCGATTCTTGAAGCCGATGCAAAAGCAGAAAATCAAACAACTGCTTTTATTGCAAAACGGAATTTAAATATAATAA
AGAAAGCAGTAATTTATCAAAATGAAAATTATTCACTGCTTCCAAAAAGACTTGGATATACGGCATTGTTGATTTTAATT
ATTGGTATAATTTTATATGTAGTCGGGAAAATTTTTAACAGAATAAAATTATACATCTTAAAAAACAGCGACAAGTATTT
TAAGGGTGTCAGTTACAATAATATAAATTTTTTATCGCCTCAAAGACAGCAGTCATTATTAATGCGATTGTATGGCTTTA
TAAAAATTGCAGCCTTAATTTTTATCGTTTATCTTTCGCTTCCTGCCTTATTCAGTATTTTTCCTGCCACTGAAAATTAT
ACCAAAACATTGCTGCACTGGATTCTTTCGCCTGCAAAATCGACGTTAATGGGCTTTATTCGATTTTTACCAAGTTTAGT
TACTATAATCGTTATAATTTTCATTTTTAAGTATGCAATAAAAGTCATTAAGTTCTTTTTTGACGAAATAAAACAAGAGA
ATATCAAAATTGATGGTTTTTACAGCGATTGGGCAATGCCTACCTTTAATATCATCAGATTATTGCTTTTTGCTTTTATG
ATTGTAGTTATATTTCCCTATCTTCCCGGTTCAGATTCTCCTATTTTTAAAGGTGTTTCAGTGTTTGTCGGGGTTTTATT
TTCTTTAGGTTCATCAAATGCCATAGCCAATATGGTAGCCGGATTAGTTATTACTTATATGCGTCCGTTTAAAATTGGCG
ATTTTATAAAAATTGGCGATGTAAGCGGTGAAGTAATAGAAAAAACAGCTTTAGTAACCCGAATCAGAACTCCAAAATTT
GAAGATATTACCATTCCCAATTCAACTGTTTTATCTAGCACTTCAACCAATTTTTCTGCTAATACGAAACAAAACAATAA
TGGTTTACTAATACATACAACAGTAACAATTGGTTACGATGTTCCGTGGAAAGACATTCATAAAGCATTAATAGATGCCG
CTCTAAAAACAGAAATGACTGAAAAAGAACCAACACCTTTTGTACTCCAGACAAGTTTGGATGATTTTTATGTTTCGTAT
CAAATCAATGTTTACACAAAAGAACCAACAAAACAGCCTAGAATTTATTCATCACTCCATCAAAATATTCAGGATTCTTT
TAATGCTGCCAGAATAGAGATTATGTCACCTCATTACAGTGCTTTAAGAGATGGAAACACTACTACAATACCGCCAGATT
ATCTAAATGATGATTATGAACCTTCATTTTTTAATATTAAGAATAAAAGTTAG

Upstream 100 bases:

>100_bases
ATTTAGTACGATTTTATTTCGAAATAAGGAGGGTAATTTAAAATCGAATCTATTTTGTTTTTATATTTGTTAGTAGTAAC
TAACTAATTATAAATGAAAT

Downstream 100 bases:

>100_bases
TCTCTTTTTGTAAGATGTTGAAAATGTGAATATAATCTTAACTTTTTTGGCTCATTTCTTTGAAATTCAATTTATTAAAA
TTAATTTTATGTTCATTTTT

Product: mechanosensitive ion channel MscS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 550; Mature: 550

Protein sequence:

>550_residues
MKNKLLWFLAVFTVSFYWASFAQKSNHDTLHKIEVKPKLKPYPVAPFKDTLFFIYNKVGSFSAENRAHAITEKIRKLYED
SFFEQDSILVVPSDLSQDIIYKNDFIIMSILEADAKAENQTTAFIAKRNLNIIKKAVIYQNENYSLLPKRLGYTALLILI
IGIILYVVGKIFNRIKLYILKNSDKYFKGVSYNNINFLSPQRQQSLLMRLYGFIKIAALIFIVYLSLPALFSIFPATENY
TKTLLHWILSPAKSTLMGFIRFLPSLVTIIVIIFIFKYAIKVIKFFFDEIKQENIKIDGFYSDWAMPTFNIIRLLLFAFM
IVVIFPYLPGSDSPIFKGVSVFVGVLFSLGSSNAIANMVAGLVITYMRPFKIGDFIKIGDVSGEVIEKTALVTRIRTPKF
EDITIPNSTVLSSTSTNFSANTKQNNNGLLIHTTVTIGYDVPWKDIHKALIDAALKTEMTEKEPTPFVLQTSLDDFYVSY
QINVYTKEPTKQPRIYSSLHQNIQDSFNAARIEIMSPHYSALRDGNTTTIPPDYLNDDYEPSFFNIKNKS

Sequences:

>Translated_550_residues
MKNKLLWFLAVFTVSFYWASFAQKSNHDTLHKIEVKPKLKPYPVAPFKDTLFFIYNKVGSFSAENRAHAITEKIRKLYED
SFFEQDSILVVPSDLSQDIIYKNDFIIMSILEADAKAENQTTAFIAKRNLNIIKKAVIYQNENYSLLPKRLGYTALLILI
IGIILYVVGKIFNRIKLYILKNSDKYFKGVSYNNINFLSPQRQQSLLMRLYGFIKIAALIFIVYLSLPALFSIFPATENY
TKTLLHWILSPAKSTLMGFIRFLPSLVTIIVIIFIFKYAIKVIKFFFDEIKQENIKIDGFYSDWAMPTFNIIRLLLFAFM
IVVIFPYLPGSDSPIFKGVSVFVGVLFSLGSSNAIANMVAGLVITYMRPFKIGDFIKIGDVSGEVIEKTALVTRIRTPKF
EDITIPNSTVLSSTSTNFSANTKQNNNGLLIHTTVTIGYDVPWKDIHKALIDAALKTEMTEKEPTPFVLQTSLDDFYVSY
QINVYTKEPTKQPRIYSSLHQNIQDSFNAARIEIMSPHYSALRDGNTTTIPPDYLNDDYEPSFFNIKNKS
>Mature_550_residues
MKNKLLWFLAVFTVSFYWASFAQKSNHDTLHKIEVKPKLKPYPVAPFKDTLFFIYNKVGSFSAENRAHAITEKIRKLYED
SFFEQDSILVVPSDLSQDIIYKNDFIIMSILEADAKAENQTTAFIAKRNLNIIKKAVIYQNENYSLLPKRLGYTALLILI
IGIILYVVGKIFNRIKLYILKNSDKYFKGVSYNNINFLSPQRQQSLLMRLYGFIKIAALIFIVYLSLPALFSIFPATENY
TKTLLHWILSPAKSTLMGFIRFLPSLVTIIVIIFIFKYAIKVIKFFFDEIKQENIKIDGFYSDWAMPTFNIIRLLLFAFM
IVVIFPYLPGSDSPIFKGVSVFVGVLFSLGSSNAIANMVAGLVITYMRPFKIGDFIKIGDVSGEVIEKTALVTRIRTPKF
EDITIPNSTVLSSTSTNFSANTKQNNNGLLIHTTVTIGYDVPWKDIHKALIDAALKTEMTEKEPTPFVLQTSLDDFYVSY
QINVYTKEPTKQPRIYSSLHQNIQDSFNAARIEIMSPHYSALRDGNTTTIPPDYLNDDYEPSFFNIKNKS

Specific function: May play a role in resistance to osmotic downshock [H]

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI1786670, Length=237, Percent_Identity=25.3164556962025, Blast_Score=70, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR006686
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 62896; Mature: 62896

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNKLLWFLAVFTVSFYWASFAQKSNHDTLHKIEVKPKLKPYPVAPFKDTLFFIYNKVGS
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCC
FSAENRAHAITEKIRKLYEDSFFEQDSILVVPSDLSQDIIYKNDFIIMSILEADAKAENQ
CCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCEECCCEEEEEEHHHCCCCCCC
TTAFIAKRNLNIIKKAVIYQNENYSLLPKRLGYTALLILIIGIILYVVGKIFNRIKLYIL
CEEEEECCCHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEE
KNSDKYFKGVSYNNINFLSPQRQQSLLMRLYGFIKIAALIFIVYLSLPALFSIFPATENY
ECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
TKTLLHWILSPAKSTLMGFIRFLPSLVTIIVIIFIFKYAIKVIKFFFDEIKQENIKIDGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEE
YSDWAMPTFNIIRLLLFAFMIVVIFPYLPGSDSPIFKGVSVFVGVLFSLGSSNAIANMVA
ECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHH
GLVITYMRPFKIGDFIKIGDVSGEVIEKTALVTRIRTPKFEDITIPNSTVLSSTSTNFSA
HHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCEEECCCCCEECCCCCCCCC
NTKQNNNGLLIHTTVTIGYDVPWKDIHKALIDAALKTEMTEKEPTPFVLQTSLDDFYVSY
CCCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEE
QINVYTKEPTKQPRIYSSLHQNIQDSFNAARIEIMSPHYSALRDGNTTTIPPDYLNDDYE
EEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHCCCCCCCCCHHHCCCCCC
PSFFNIKNKS
CCEEECCCCC
>Mature Secondary Structure
MKNKLLWFLAVFTVSFYWASFAQKSNHDTLHKIEVKPKLKPYPVAPFKDTLFFIYNKVGS
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCC
FSAENRAHAITEKIRKLYEDSFFEQDSILVVPSDLSQDIIYKNDFIIMSILEADAKAENQ
CCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCEECCCEEEEEEHHHCCCCCCC
TTAFIAKRNLNIIKKAVIYQNENYSLLPKRLGYTALLILIIGIILYVVGKIFNRIKLYIL
CEEEEECCCHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEE
KNSDKYFKGVSYNNINFLSPQRQQSLLMRLYGFIKIAALIFIVYLSLPALFSIFPATENY
ECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
TKTLLHWILSPAKSTLMGFIRFLPSLVTIIVIIFIFKYAIKVIKFFFDEIKQENIKIDGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEE
YSDWAMPTFNIIRLLLFAFMIVVIFPYLPGSDSPIFKGVSVFVGVLFSLGSSNAIANMVA
ECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHH
GLVITYMRPFKIGDFIKIGDVSGEVIEKTALVTRIRTPKFEDITIPNSTVLSSTSTNFSA
HHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCEEECCCCCEECCCCCCCCC
NTKQNNNGLLIHTTVTIGYDVPWKDIHKALIDAALKTEMTEKEPTPFVLQTSLDDFYVSY
CCCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEE
QINVYTKEPTKQPRIYSSLHQNIQDSFNAARIEIMSPHYSALRDGNTTTIPPDYLNDDYE
EEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHCCCCCCCCCHHHCCCCCC
PSFFNIKNKS
CCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]