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The map label for this gene is purM [H]

Identifier: 146300108

GI number: 146300108

Start: 2824569

End: 2825747

Strand: Direct

Name: purM [H]

Synonym: Fjoh_2353

Alternate gene names: 146300108

Gene position: 2824569-2825747 (Clockwise)

Preceding gene: 146300107

Following gene: 146300109

Centisome position: 46.33

GC content: 36.13

Gene sequence:

>1179_bases
ATGAGTTCAGATTCTAGCAAAAGATATGCACAAAGAGGTGTTTCGGCATCAAAAGAAGACGTACATAACGCTATAAAAAA
TATTGACAAAGGTTTATTTCCGCAGGCATTTTGTAAAATTGTCCCAGATTATTTAACTCAGGACAATGAGCACTGCTTAA
TTATGCATGCTGACGGAGCGGGTACAAAATCATCTTTAGCTTATATGTACTGGAAAGAAACCGGAGATCTTTCGGTTTGG
AAAGGAATTGCTCAGGATGCCTTAATCATGAATATTGACGATTTGTTATGTGTTGGCGCAACAGATAATATCTTGCTTTC
TTCAACTATTGGAAGAAATAAAAACTTAATTCCTGCTGAAGTTATCTCAGCAATTATTAACGGAACAGAGGAATTAATAA
ACGAATTAAAATCATTTGGCGTAACAATTCATTCAACAGGAGGAGAAACTGCTGACGTTGGAGATGTTGTTCGTACCATT
ATTGTAGATTCAACTGTTACCGCTCGTATGAAACGTGAGGATGTTGTAGACAATGCTAATATTAAAGCTGGAGATGTAAT
TGTTGGTTTGGCTTCTTTTGGTCAGGCTTCTTACGAAAAAGGATATAACGGAGGAATGGGAAGTAACGGATTAACTTCTG
CCCGTCATGATGTTTTTGGTAAATATTTAGCAAAAAAATATCCTGAAAGTTACGATGCAGCTGTTCCAGAAGAATTAATT
TATTCTGGTCAGGTAAATTTAACCGATGCTGTTGAAAACAGTCCAATAAATGCAGGTCAGCTGGTACTTTCACCAACAAG
AACTTACGCACCAATTATCAAGAAAATTTTAGACAAATACACACCAAAAGACATTCACGGAATGGTGCATTGCAGCGGTG
GTGCGCAGACTAAAATTTTACATTTCGTAAAAGACTTACACGTTATAAAAGACAATTTATTTCCGGTGCCGCCATTGTTC
AAGTTAATTCAGGAACAATCAAAAACAGATTGGAAAGAAATGTATCAGGTTTTTAACTGCGGTCACAGAATGGAGCTTTA
CGTTCCGGAAAATATCGCACAGGATATTATCGAAATTTCAAAATCATTCAATGTTGATGCACAAATCGTGGGTAGAGTAG
AAGCTTCAGATTCTAAAAAACTTACAATTACAAGCGAATACGGAACATTTGAATATTAA

Upstream 100 bases:

>100_bases
TCAAAATCTGCCGATTTTTTTATGAATCATACAGACGAATCAATCGAAGAATTTAAAAAAAGGGATTATCTTTGCACCAC
ATCAACACAAACTAATTTTC

Downstream 100 bases:

>100_bases
TTTTTAAAGTTACAAAGGTTCAAAGGTTCAGAGTTGCAAAGACTTTGAAACTTTTAAAATAATTATTAAATTTAGAGATG
CATAATTGTGCATCTCTATG

Product: phosphoribosylformylglycinamidine cyclo-ligase

Products: NA

Alternate protein names: AIR synthase; AIRS; Phosphoribosyl-aminoimidazole synthetase [H]

Number of amino acids: Translated: 392; Mature: 391

Protein sequence:

>392_residues
MSSDSSKRYAQRGVSASKEDVHNAIKNIDKGLFPQAFCKIVPDYLTQDNEHCLIMHADGAGTKSSLAYMYWKETGDLSVW
KGIAQDALIMNIDDLLCVGATDNILLSSTIGRNKNLIPAEVISAIINGTEELINELKSFGVTIHSTGGETADVGDVVRTI
IVDSTVTARMKREDVVDNANIKAGDVIVGLASFGQASYEKGYNGGMGSNGLTSARHDVFGKYLAKKYPESYDAAVPEELI
YSGQVNLTDAVENSPINAGQLVLSPTRTYAPIIKKILDKYTPKDIHGMVHCSGGAQTKILHFVKDLHVIKDNLFPVPPLF
KLIQEQSKTDWKEMYQVFNCGHRMELYVPENIAQDIIEISKSFNVDAQIVGRVEASDSKKLTITSEYGTFEY

Sequences:

>Translated_392_residues
MSSDSSKRYAQRGVSASKEDVHNAIKNIDKGLFPQAFCKIVPDYLTQDNEHCLIMHADGAGTKSSLAYMYWKETGDLSVW
KGIAQDALIMNIDDLLCVGATDNILLSSTIGRNKNLIPAEVISAIINGTEELINELKSFGVTIHSTGGETADVGDVVRTI
IVDSTVTARMKREDVVDNANIKAGDVIVGLASFGQASYEKGYNGGMGSNGLTSARHDVFGKYLAKKYPESYDAAVPEELI
YSGQVNLTDAVENSPINAGQLVLSPTRTYAPIIKKILDKYTPKDIHGMVHCSGGAQTKILHFVKDLHVIKDNLFPVPPLF
KLIQEQSKTDWKEMYQVFNCGHRMELYVPENIAQDIIEISKSFNVDAQIVGRVEASDSKKLTITSEYGTFEY
>Mature_391_residues
SSDSSKRYAQRGVSASKEDVHNAIKNIDKGLFPQAFCKIVPDYLTQDNEHCLIMHADGAGTKSSLAYMYWKETGDLSVWK
GIAQDALIMNIDDLLCVGATDNILLSSTIGRNKNLIPAEVISAIINGTEELINELKSFGVTIHSTGGETADVGDVVRTII
VDSTVTARMKREDVVDNANIKAGDVIVGLASFGQASYEKGYNGGMGSNGLTSARHDVFGKYLAKKYPESYDAAVPEELIY
SGQVNLTDAVENSPINAGQLVLSPTRTYAPIIKKILDKYTPKDIHGMVHCSGGAQTKILHFVKDLHVIKDNLFPVPPLFK
LIQEQSKTDWKEMYQVFNCGHRMELYVPENIAQDIIEISKSFNVDAQIVGRVEASDSKKLTITSEYGTFEY

Specific function: De novo purine biosynthesis; fifth step. [C]

COG id: COG0150

COG function: function code F; Phosphoribosylaminoimidazole (AIR) synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AIR synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788845, Length=354, Percent_Identity=24.5762711864407, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: 180 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR004733
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =6.3.3.1 [H]

Molecular weight: Translated: 43026; Mature: 42895

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSDSSKRYAQRGVSASKEDVHNAIKNIDKGLFPQAFCKIVPDYLTQDNEHCLIMHADGA
CCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEECCCC
GTKSSLAYMYWKETGDLSVWKGIAQDALIMNIDDLLCVGATDNILLSSTIGRNKNLIPAE
CCCCCEEEEEEECCCCHHHHHHHHHCCEEEECCCEEEECCCCCEEEEECCCCCCCCCHHH
VISAIINGTEELINELKSFGVTIHSTGGETADVGDVVRTIIVDSTVTARMKREDVVDNAN
HHHHHHCCHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCC
IKAGDVIVGLASFGQASYEKGYNGGMGSNGLTSARHDVFGKYLAKKYPESYDAAVPEELI
CCCCCEEEEHHHCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHH
YSGQVNLTDAVENSPINAGQLVLSPTRTYAPIIKKILDKYTPKDIHGMVHCSGGAQTKIL
HCCCCCCHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCHHCEEEEECCCCHHHHH
HFVKDLHVIKDNLFPVPPLFKLIQEQSKTDWKEMYQVFNCGHRMELYVPENIAQDIIEIS
HHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEECHHHHHHHHHHH
KSFNVDAQIVGRVEASDSKKLTITSEYGTFEY
HCCCCCEEEEEEEECCCCCEEEEEECCCCCCC
>Mature Secondary Structure 
SSDSSKRYAQRGVSASKEDVHNAIKNIDKGLFPQAFCKIVPDYLTQDNEHCLIMHADGA
CCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEECCCC
GTKSSLAYMYWKETGDLSVWKGIAQDALIMNIDDLLCVGATDNILLSSTIGRNKNLIPAE
CCCCCEEEEEEECCCCHHHHHHHHHCCEEEECCCEEEECCCCCEEEEECCCCCCCCCHHH
VISAIINGTEELINELKSFGVTIHSTGGETADVGDVVRTIIVDSTVTARMKREDVVDNAN
HHHHHHCCHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCC
IKAGDVIVGLASFGQASYEKGYNGGMGSNGLTSARHDVFGKYLAKKYPESYDAAVPEELI
CCCCCEEEEHHHCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHH
YSGQVNLTDAVENSPINAGQLVLSPTRTYAPIIKKILDKYTPKDIHGMVHCSGGAQTKIL
HCCCCCCHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCHHCEEEEECCCCHHHHH
HFVKDLHVIKDNLFPVPPLFKLIQEQSKTDWKEMYQVFNCGHRMELYVPENIAQDIIEIS
HHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEECHHHHHHHHHHH
KSFNVDAQIVGRVEASDSKKLTITSEYGTFEY
HCCCCCEEEEEEEECCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA