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The map label for this gene is lytS [H]

Identifier: 146299920

GI number: 146299920

Start: 2620938

End: 2621978

Strand: Direct

Name: lytS [H]

Synonym: Fjoh_2164

Alternate gene names: 146299920

Gene position: 2620938-2621978 (Clockwise)

Preceding gene: 146299918

Following gene: 146299921

Centisome position: 42.99

GC content: 28.63

Gene sequence:

>1041_bases
ATGAAACTTAAAATACCTTTTTACTACCATATTATTCTTTTTGCCGGGTTGTTTTTAACCTTTTGTCTTTGGGATTACGG
AATAAATAACCGACTAGAGATGGTACAGCAAACCAAAATTTATTTCTGGCTTACATCGACTTTTATGCTTTCGGTTTTTG
CGTCTTACCTTCTCAATTTTTATACTTTTTGCAGCTGGTTTTTAAACAAAAAGAAAATTCTTTTTTACTTTTTAAGTATT
CCGGTTTCTTTAGTCATTTTTGCAGGTATAAGGTATTTTTTTCAGGAAATAATTATGTTTCATTTTACAGGAATGCATAA
TTATTTTGAAGAAAGCAGAGAAATAACGTTCTACATAAAAGACAATTTTTTATACGGACTTCCTGCTGTAATTTTAAGTG
CTTTCAGTTATTTATTCTGGGAATTTCAAAATACACAGAAACAAAATCAGGAATTAATGCTGGAGAATAAAAAAGCCGAA
TTTCAAATGCTGAAAGCACAAGTGAGTCCGCATTTTTTATTTAATACTTTGAATTCATTTTATAGTCAGTTAATTTTAAA
AGATGATAAAATGGCTTCAGATGTTTTGGTTCTTTCAGATCTGCTTCGGTATGTAATTACAGAAACAGACAAAGATGAGG
CAATACTATCAAGGGAAATTCAGTTTATAAAAAACTATATTCATTTACAGAGAAAACGATTTGAAGATCAATTGTATTTG
GATTTTTCTGTTGAAGGAGATTATTCTAATGAGAGAATATTGTCATCGGCATTAATTCATTTTGTTGAAAATGTTTTTAA
ACACGGAAAATTTAATAAAGAAAAAGAAACCGCAGTTATTTCCATTAAAATAAAAGATGAGTTTCTGGAAATCTCAACTT
TTAATTATAATGCCGACGGTGAAAATTATTCCTCGACCGGAATTGGTTTTACGAACTTAATAAAAAGGTTGGAATATGCT
TATAAAAACCAATTTGTACTTGAAAAAAGCGAAGAAAATAATACCTTTAAGACATACTTAAAAATACCGCTAAAAAAATA
A

Upstream 100 bases:

>100_bases
ATGATTTTTGATGTTTTTGTCACTAAGAAAAACTGGTTTTGTATAAACAACACTTTCGTTTCAGTGCATAATTGTATTTT
TGGTTTCATAACTGCTTTCT

Downstream 100 bases:

>100_bases
TTTATGGCTTTTAAATGTATTATTGTTGATGATGAACCGCCTGCAACACGGATACTCGAAAATTATATTGGAAAAGTAAG
CTTTTTAGAAAAAACCGAAG

Product: signal transduction histidine kinase LytS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MKLKIPFYYHIILFAGLFLTFCLWDYGINNRLEMVQQTKIYFWLTSTFMLSVFASYLLNFYTFCSWFLNKKKILFYFLSI
PVSLVIFAGIRYFFQEIIMFHFTGMHNYFEESREITFYIKDNFLYGLPAVILSAFSYLFWEFQNTQKQNQELMLENKKAE
FQMLKAQVSPHFLFNTLNSFYSQLILKDDKMASDVLVLSDLLRYVITETDKDEAILSREIQFIKNYIHLQRKRFEDQLYL
DFSVEGDYSNERILSSALIHFVENVFKHGKFNKEKETAVISIKIKDEFLEISTFNYNADGENYSSTGIGFTNLIKRLEYA
YKNQFVLEKSEENNTFKTYLKIPLKK

Sequences:

>Translated_346_residues
MKLKIPFYYHIILFAGLFLTFCLWDYGINNRLEMVQQTKIYFWLTSTFMLSVFASYLLNFYTFCSWFLNKKKILFYFLSI
PVSLVIFAGIRYFFQEIIMFHFTGMHNYFEESREITFYIKDNFLYGLPAVILSAFSYLFWEFQNTQKQNQELMLENKKAE
FQMLKAQVSPHFLFNTLNSFYSQLILKDDKMASDVLVLSDLLRYVITETDKDEAILSREIQFIKNYIHLQRKRFEDQLYL
DFSVEGDYSNERILSSALIHFVENVFKHGKFNKEKETAVISIKIKDEFLEISTFNYNADGENYSSTGIGFTNLIKRLEYA
YKNQFVLEKSEENNTFKTYLKIPLKK
>Mature_346_residues
MKLKIPFYYHIILFAGLFLTFCLWDYGINNRLEMVQQTKIYFWLTSTFMLSVFASYLLNFYTFCSWFLNKKKILFYFLSI
PVSLVIFAGIRYFFQEIIMFHFTGMHNYFEESREITFYIKDNFLYGLPAVILSAFSYLFWEFQNTQKQNQELMLENKKAE
FQMLKAQVSPHFLFNTLNSFYSQLILKDDKMASDVLVLSDLLRYVITETDKDEAILSREIQFIKNYIHLQRKRFEDQLYL
DFSVEGDYSNERILSSALIHFVENVFKHGKFNKEKETAVISIKIKDEFLEISTFNYNADGENYSSTGIGFTNLIKRLEYA
YKNQFVLEKSEENNTFKTYLKIPLKK

Specific function: Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788446, Length=209, Percent_Identity=25.8373205741627, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1788723, Length=129, Percent_Identity=32.5581395348837, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR010559
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 41410; Mature: 41410

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLKIPFYYHIILFAGLFLTFCLWDYGINNRLEMVQQTKIYFWLTSTFMLSVFASYLLNF
CEEECHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHH
YTFCSWFLNKKKILFYFLSIPVSLVIFAGIRYFFQEIIMFHFTGMHNYFEESREITFYIK
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
DNFLYGLPAVILSAFSYLFWEFQNTQKQNQELMLENKKAEFQMLKAQVSPHFLFNTLNSF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHH
YSQLILKDDKMASDVLVLSDLLRYVITETDKDEAILSREIQFIKNYIHLQRKRFEDQLYL
HHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
DFSVEGDYSNERILSSALIHFVENVFKHGKFNKEKETAVISIKIKDEFLEISTFNYNADG
EEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCEEEEEEEEECCCC
ENYSSTGIGFTNLIKRLEYAYKNQFVLEKSEENNTFKTYLKIPLKK
CCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCEEEEEEECCCC
>Mature Secondary Structure
MKLKIPFYYHIILFAGLFLTFCLWDYGINNRLEMVQQTKIYFWLTSTFMLSVFASYLLNF
CEEECHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHH
YTFCSWFLNKKKILFYFLSIPVSLVIFAGIRYFFQEIIMFHFTGMHNYFEESREITFYIK
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
DNFLYGLPAVILSAFSYLFWEFQNTQKQNQELMLENKKAEFQMLKAQVSPHFLFNTLNSF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHH
YSQLILKDDKMASDVLVLSDLLRYVITETDKDEAILSREIQFIKNYIHLQRKRFEDQLYL
HHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
DFSVEGDYSNERILSSALIHFVENVFKHGKFNKEKETAVISIKIKDEFLEISTFNYNADG
EEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCEEEEEEEEECCCC
ENYSSTGIGFTNLIKRLEYAYKNQFVLEKSEENNTFKTYLKIPLKK
CCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12663927 [H]