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The map label for this gene is sucC [H]

Identifier: 146299918

GI number: 146299918

Start: 2618512

End: 2619705

Strand: Direct

Name: sucC [H]

Synonym: Fjoh_2162

Alternate gene names: 146299918

Gene position: 2618512-2619705 (Clockwise)

Preceding gene: 146299914

Following gene: 146299920

Centisome position: 42.95

GC content: 38.44

Gene sequence:

>1194_bases
ATGAACATACACGAATATCAAGGAAAAGAAATTTTAGCGAGTTACGGAGTACGCGTACAACGCGGAATTGTGGCTAACAA
TGCGGTTGAAGCTGTAGCTGCTGCAAAACAATTAACTGCCGAAACTGGTACAGGATGGCATGTAATAAAAGCACAAATTC
ACGCAGGTGGTCGTGGAAAAGGTGGTGGAGTTAAGCTGGCAAAAAACTTACAACAAGTTGAAGAGTTAGCAGAACAAATC
ATCGGAATGCAGTTGATTACACCTCAGACTCCGCCTGAAGGTAAAAAAGTAAATAAGGTATTAGTTGCAGAAGATGTTTA
CTATCCAGGTGAAAGCGAAACTTCTGAATTTTATGTTTCTGTTTTATTGAATAGAGGTACAGGACGCAACATGATTATGT
ATTCTACTGAAGGTGGAATGGATATCGAAGAAGTTGCTGAGCATACTCCACACTTAATCTTTACTGAAGAAATTGATCCA
ACTGTTGGATTACAAGGTTTCCAGGCTAGAAGAATTGCTTTTAACTTAGGACTTTCTGGAAATGCTTTCAAAGAAATGGT
TAAATTCATCGACGCACTTTACAATGCTTACATTGGTTCTGATGCTTCTATGTTTGAAATCAACCCAGTTTTAAAAACTT
CTGATAACAAAATCTTAGCGGTTGATGCTAAAGTTAACATCGACGATAACGCTTTATACAGACAACCTAAATATGCTGAA
ATGAGAGATATCCGTGAGGAGAATCCAATCGAAGTTGAAGCTAAAGAAGTTGGTCTAAACTATGTTGACCTTGACGGTAC
TGTAGGATGTATGGTAAACGGAGCTGGTCTTGCAATGGCAACTATGGATTTAATTAAATATGCTGGTTTTGAGCCTGCTA
ACTTCCTTGACGTAGGAGGAACTGCTGATGCAAAACGTGTTGAAACAGCTTTCAGAATTATCTTGAAAGATCCAAACGTA
AAAGCTATCTTAATTAACATCTTCGGAGGTATTGTTCGTTGTGACCGTGTTGCTCAAGGTGTTGTTGACGCTTACAAAAA
CATGGGAGACGCTATTAAAGTGCCAATTATCGTTCGTTTGCAAGGAACAAATGCTGAAATTGCAAAAGAATTAATTGACA
ACTCTGGTATGCCAATCTTATCTGCAGTTCAATTCCAAGAAGCTGCTGACCAAGTTAAAGCTGCTCTTTCTTAA

Upstream 100 bases:

>100_bases
TATTATTTAATTGAAAAAGATTTTACTATTAAGTTGTATTTTGTTACTTTTGTCGCACTTTTATTCTGAAATAAATTCAG
AACCAGACAAATTCTATATT

Downstream 100 bases:

>100_bases
TTAAATAAGAAATCAATTTATATAGAAAATCCCTCCATTGTGGAGGGATTTTTTTTAGAGTTAATTTAACCGCAAAGGGC
GCAAGTTTTTTGTCAAGGAT

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MNIHEYQGKEILASYGVRVQRGIVANNAVEAVAAAKQLTAETGTGWHVIKAQIHAGGRGKGGGVKLAKNLQQVEELAEQI
IGMQLITPQTPPEGKKVNKVLVAEDVYYPGESETSEFYVSVLLNRGTGRNMIMYSTEGGMDIEEVAEHTPHLIFTEEIDP
TVGLQGFQARRIAFNLGLSGNAFKEMVKFIDALYNAYIGSDASMFEINPVLKTSDNKILAVDAKVNIDDNALYRQPKYAE
MRDIREENPIEVEAKEVGLNYVDLDGTVGCMVNGAGLAMATMDLIKYAGFEPANFLDVGGTADAKRVETAFRIILKDPNV
KAILINIFGGIVRCDRVAQGVVDAYKNMGDAIKVPIIVRLQGTNAEIAKELIDNSGMPILSAVQFQEAADQVKAALS

Sequences:

>Translated_397_residues
MNIHEYQGKEILASYGVRVQRGIVANNAVEAVAAAKQLTAETGTGWHVIKAQIHAGGRGKGGGVKLAKNLQQVEELAEQI
IGMQLITPQTPPEGKKVNKVLVAEDVYYPGESETSEFYVSVLLNRGTGRNMIMYSTEGGMDIEEVAEHTPHLIFTEEIDP
TVGLQGFQARRIAFNLGLSGNAFKEMVKFIDALYNAYIGSDASMFEINPVLKTSDNKILAVDAKVNIDDNALYRQPKYAE
MRDIREENPIEVEAKEVGLNYVDLDGTVGCMVNGAGLAMATMDLIKYAGFEPANFLDVGGTADAKRVETAFRIILKDPNV
KAILINIFGGIVRCDRVAQGVVDAYKNMGDAIKVPIIVRLQGTNAEIAKELIDNSGMPILSAVQFQEAADQVKAALS
>Mature_397_residues
MNIHEYQGKEILASYGVRVQRGIVANNAVEAVAAAKQLTAETGTGWHVIKAQIHAGGRGKGGGVKLAKNLQQVEELAEQI
IGMQLITPQTPPEGKKVNKVLVAEDVYYPGESETSEFYVSVLLNRGTGRNMIMYSTEGGMDIEEVAEHTPHLIFTEEIDP
TVGLQGFQARRIAFNLGLSGNAFKEMVKFIDALYNAYIGSDASMFEINPVLKTSDNKILAVDAKVNIDDNALYRQPKYAE
MRDIREENPIEVEAKEVGLNYVDLDGTVGCMVNGAGLAMATMDLIKYAGFEPANFLDVGGTADAKRVETAFRIILKDPNV
KAILINIFGGIVRCDRVAQGVVDAYKNMGDAIKVPIIVRLQGTNAEIAKELIDNSGMPILSAVQFQEAADQVKAALS

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI157779135, Length=394, Percent_Identity=45.6852791878173, Blast_Score=329, Evalue=3e-90,
Organism=Homo sapiens, GI11321583, Length=399, Percent_Identity=43.1077694235589, Blast_Score=309, Evalue=3e-84,
Organism=Homo sapiens, GI294862256, Length=373, Percent_Identity=46.112600536193, Blast_Score=307, Evalue=1e-83,
Organism=Escherichia coli, GI1786948, Length=398, Percent_Identity=44.9748743718593, Blast_Score=332, Evalue=2e-92,
Organism=Caenorhabditis elegans, GI17539378, Length=405, Percent_Identity=43.9506172839506, Blast_Score=317, Evalue=7e-87,
Organism=Caenorhabditis elegans, GI17567829, Length=398, Percent_Identity=42.713567839196, Blast_Score=302, Evalue=2e-82,
Organism=Saccharomyces cerevisiae, GI6321683, Length=402, Percent_Identity=43.0348258706468, Blast_Score=303, Evalue=3e-83,
Organism=Drosophila melanogaster, GI161078106, Length=397, Percent_Identity=43.5768261964735, Blast_Score=307, Evalue=1e-83,
Organism=Drosophila melanogaster, GI24645208, Length=397, Percent_Identity=43.5768261964735, Blast_Score=307, Evalue=1e-83,
Organism=Drosophila melanogaster, GI21356231, Length=406, Percent_Identity=43.8423645320197, Blast_Score=305, Evalue=5e-83,
Organism=Drosophila melanogaster, GI281361397, Length=398, Percent_Identity=43.4673366834171, Blast_Score=303, Evalue=2e-82,
Organism=Drosophila melanogaster, GI281361395, Length=398, Percent_Identity=43.4673366834171, Blast_Score=303, Evalue=2e-82,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 43067; Mature: 43067

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIHEYQGKEILASYGVRVQRGIVANNAVEAVAAAKQLTAETGTGWHVIKAQIHAGGRGK
CCCCHHCCHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCC
GGGVKLAKNLQQVEELAEQIIGMQLITPQTPPEGKKVNKVLVAEDVYYPGESETSEFYVS
CCCHHHHHHHHHHHHHHHHHHCEEEECCCCCCCCCCCCEEEEEEEEECCCCCCCHHEEEE
VLLNRGTGRNMIMYSTEGGMDIEEVAEHTPHLIFTEEIDPTVGLQGFQARRIAFNLGLSG
EEEECCCCCEEEEEECCCCCCHHHHHHHCCCEEEECCCCCCCCCCCCEEEEEEEEECCCC
NAFKEMVKFIDALYNAYIGSDASMFEINPVLKTSDNKILAVDAKVNIDDNALYRQPKYAE
HHHHHHHHHHHHHHHHHCCCCCCEEEECCCEECCCCEEEEEEEEEECCCCHHCCCCCHHH
MRDIREENPIEVEAKEVGLNYVDLDGTVGCMVNGAGLAMATMDLIKYAGFEPANFLDVGG
HHHCCCCCCCEEEHHHCCCEEEECCCCEEEEEECCCHHHHHHHHHHHCCCCCCCEEECCC
TADAKRVETAFRIILKDPNVKAILINIFGGIVRCDRVAQGVVDAYKNMGDAIKVPIIVRL
CCCHHHHHHEEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCEEECEEEEEE
QGTNAEIAKELIDNSGMPILSAVQFQEAADQVKAALS
ECCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNIHEYQGKEILASYGVRVQRGIVANNAVEAVAAAKQLTAETGTGWHVIKAQIHAGGRGK
CCCCHHCCHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCC
GGGVKLAKNLQQVEELAEQIIGMQLITPQTPPEGKKVNKVLVAEDVYYPGESETSEFYVS
CCCHHHHHHHHHHHHHHHHHHCEEEECCCCCCCCCCCCEEEEEEEEECCCCCCCHHEEEE
VLLNRGTGRNMIMYSTEGGMDIEEVAEHTPHLIFTEEIDPTVGLQGFQARRIAFNLGLSG
EEEECCCCCEEEEEECCCCCCHHHHHHHCCCEEEECCCCCCCCCCCCEEEEEEEEECCCC
NAFKEMVKFIDALYNAYIGSDASMFEINPVLKTSDNKILAVDAKVNIDDNALYRQPKYAE
HHHHHHHHHHHHHHHHHCCCCCCEEEECCCEECCCCEEEEEEEEEECCCCHHCCCCCHHH
MRDIREENPIEVEAKEVGLNYVDLDGTVGCMVNGAGLAMATMDLIKYAGFEPANFLDVGG
HHHCCCCCCCEEEHHHCCCEEEECCCCEEEEEECCCHHHHHHHHHHHCCCCCCCEEECCC
TADAKRVETAFRIILKDPNVKAILINIFGGIVRCDRVAQGVVDAYKNMGDAIKVPIIVRL
CCCHHHHHHEEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCEEECEEEEEE
QGTNAEIAKELIDNSGMPILSAVQFQEAADQVKAALS
ECCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA