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The map label for this gene is yfnA [H]

Identifier: 146299886

GI number: 146299886

Start: 2578206

End: 2580137

Strand: Direct

Name: yfnA [H]

Synonym: Fjoh_2130

Alternate gene names: 146299886

Gene position: 2578206-2580137 (Clockwise)

Preceding gene: 146299885

Following gene: 146299888

Centisome position: 42.29

GC content: 36.49

Gene sequence:

>1932_bases
ATGGCATTATCAAGTTTATTCCGAAAGAAAACAGTACAGGATATTCTGAAGCAGGTTGCTCAGAATGAAACAGACGGTCA
TAATGCCTTAGGAAAACATTTGACAACTAAGGATTTAACAGCCTTCGGAATAGCGGCGATTGTTGGAGCGGGAATTTTCA
GCACGATTGGAAAAGCCAGTGCAGACGGCGGACCAGCTGTAATTTTCTTGTTCTTATTTACTGCTTTGGCTTGTAGTTTT
GCTGCCTTTGCTTACGCCGAATTTGCATCGATGGTTCCGGTTTCAGGAAGTGCTTATACGTATTCTTATGTTGCTTTTGG
AGAATTAATTGCCTGGATAATCGGCTGGGCTTTAATTATGGAATATGCCGTTGGAAACATTACTGTTGCCATATCGTGGA
GTGATTATTTTACCGGACTGCTCCAGAGTGGCGGTATTCATCTCCCGCAATGGATTCAGATGGATTATTTAACCGCTTCA
AACGGTTTTAAAGATGCTGAAGCTTTAATAAGTGCAGGAAAATCTCCTGAAAATTTAAGTTTAGCTTTACAACAAGCGCG
AGAGGCTTGGATAACTGCCCCAACAATTGGTTCTTTTCATTTTGTGACTGATTTACCGGCATTATTTATCATTATTTTGA
TTACAGCATTGGTGTATAGAGGAATGAAAGAATCTCGTAACGCCAGTAACTTAATGGTGGTTGTAAAACTATGCGTGGTT
CTTTTAGTAATTGCAGTTGGGGTATTTTATGTTGATACAGCAAATTGGGATCCGTTTGCTCCAAATGGAGTTGGAGGGGT
TTTAAAAGGAGTTTCAGCAGTTTTCTTTGCCTATATTGGTTTTGATGCAATTTCTACAACCGCAGAAGAATGTAAAAATC
CGCAGAGAGATTTACCACGCGGCATGATGTGGGCTATTATTATTTGTACAATTCTTTATATTGCTATTGCTTTGGTTTTA
ACCGGAATGGTAAAATATCACGAATTAAATGTTGGAGATCCTCTTGCATTTGTTTTCGACAAATTAGACCTAAAATGGAT
GTCAGGAATTATTGCTGTGAGTGCAGTAGTGGCAATGGCGAGTGTTTTATTGGTTTTTCAAATGGGACAGCCTCGTATAT
GGATGAGTATGAGCCGTGATGGTTTATTACCAAAGAAATTTTCTACAGTTCACCCAAAATTCAAAACACCATCTTTTGCT
ACAATTGTAACAGGTTTTGTAGTGGCAATTCCGGCATTATTCTTAAATCTTACAATGGTAACTGATTTATGCAGTATCGG
AACATTATTTGCCTTTGTATTAGTTTGTGCAGGAGTTTTAGTGTTGCAAAACAAGCCAGAAATTCCGAGAGGAAAATTCA
AAACGCCTTATATCAATTCAAAATTTATTCTGCCAGTTTTAATGATTGCGGGATTGTATTATGCTTTTGCATTCAACAAT
AAAGCAACAATGGCGTTTATCAATAACGATCCGCAGATTTACGATGCAACTTCAATTGTTACTTCTTTAGATAAATCAGA
ATCAGAGCAGGTTTTTAAATATTTAGAAAGTATCGAAGTAAACAATAAAACTGCTGAAACATCAGATTTAGAGCATTTAT
TAGGACAATACCAAGACGACGAAGCAAAATATGCTGAAGTGGTAAAAGGATTGCCAATTGCAGATTCTGCAAAATATGAA
TCAGGTTTTGGTTTGTTCAAACACAAAATACCAATGTGGATTTTCCTATTCGTTTTAGTTGGATTAGCTGTTTGGGCTTT
TAGAAGAAACTTGTCTTTAATTCCGCTATTAGGATTAATCTGCTGTTTGTATATGATGGCCGAATTAAGCGTTTGGAACT
GGATTTATTTTACAATCTGGTTATTAATTGGACTATTAATCTACTTTACTTACAGTAGAAAAAACAGTAAACTAAACGTA
GGTAATTATTAA

Upstream 100 bases:

>100_bases
AAAATCGTTTTATATATTTGAAATAAGGATATTTTTTGCATTATTTGCAAAATAAAACAAAAACGACTGAATTAAATTAA
TTTATAACAGTAAAACATAT

Downstream 100 bases:

>100_bases
TTGTGAATTATAAATTATAAATGAAAAAGCCGTTCTGAAAATTAATCAGAACGGCTTTTTTATGTAAAGATTCATTTAAA
TTTTCTCGCGCAGATTCTGC

Product: amino acid permease-associated protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 643; Mature: 642

Protein sequence:

>643_residues
MALSSLFRKKTVQDILKQVAQNETDGHNALGKHLTTKDLTAFGIAAIVGAGIFSTIGKASADGGPAVIFLFLFTALACSF
AAFAYAEFASMVPVSGSAYTYSYVAFGELIAWIIGWALIMEYAVGNITVAISWSDYFTGLLQSGGIHLPQWIQMDYLTAS
NGFKDAEALISAGKSPENLSLALQQAREAWITAPTIGSFHFVTDLPALFIIILITALVYRGMKESRNASNLMVVVKLCVV
LLVIAVGVFYVDTANWDPFAPNGVGGVLKGVSAVFFAYIGFDAISTTAEECKNPQRDLPRGMMWAIIICTILYIAIALVL
TGMVKYHELNVGDPLAFVFDKLDLKWMSGIIAVSAVVAMASVLLVFQMGQPRIWMSMSRDGLLPKKFSTVHPKFKTPSFA
TIVTGFVVAIPALFLNLTMVTDLCSIGTLFAFVLVCAGVLVLQNKPEIPRGKFKTPYINSKFILPVLMIAGLYYAFAFNN
KATMAFINNDPQIYDATSIVTSLDKSESEQVFKYLESIEVNNKTAETSDLEHLLGQYQDDEAKYAEVVKGLPIADSAKYE
SGFGLFKHKIPMWIFLFVLVGLAVWAFRRNLSLIPLLGLICCLYMMAELSVWNWIYFTIWLLIGLLIYFTYSRKNSKLNV
GNY

Sequences:

>Translated_643_residues
MALSSLFRKKTVQDILKQVAQNETDGHNALGKHLTTKDLTAFGIAAIVGAGIFSTIGKASADGGPAVIFLFLFTALACSF
AAFAYAEFASMVPVSGSAYTYSYVAFGELIAWIIGWALIMEYAVGNITVAISWSDYFTGLLQSGGIHLPQWIQMDYLTAS
NGFKDAEALISAGKSPENLSLALQQAREAWITAPTIGSFHFVTDLPALFIIILITALVYRGMKESRNASNLMVVVKLCVV
LLVIAVGVFYVDTANWDPFAPNGVGGVLKGVSAVFFAYIGFDAISTTAEECKNPQRDLPRGMMWAIIICTILYIAIALVL
TGMVKYHELNVGDPLAFVFDKLDLKWMSGIIAVSAVVAMASVLLVFQMGQPRIWMSMSRDGLLPKKFSTVHPKFKTPSFA
TIVTGFVVAIPALFLNLTMVTDLCSIGTLFAFVLVCAGVLVLQNKPEIPRGKFKTPYINSKFILPVLMIAGLYYAFAFNN
KATMAFINNDPQIYDATSIVTSLDKSESEQVFKYLESIEVNNKTAETSDLEHLLGQYQDDEAKYAEVVKGLPIADSAKYE
SGFGLFKHKIPMWIFLFVLVGLAVWAFRRNLSLIPLLGLICCLYMMAELSVWNWIYFTIWLLIGLLIYFTYSRKNSKLNV
GNY
>Mature_642_residues
ALSSLFRKKTVQDILKQVAQNETDGHNALGKHLTTKDLTAFGIAAIVGAGIFSTIGKASADGGPAVIFLFLFTALACSFA
AFAYAEFASMVPVSGSAYTYSYVAFGELIAWIIGWALIMEYAVGNITVAISWSDYFTGLLQSGGIHLPQWIQMDYLTASN
GFKDAEALISAGKSPENLSLALQQAREAWITAPTIGSFHFVTDLPALFIIILITALVYRGMKESRNASNLMVVVKLCVVL
LVIAVGVFYVDTANWDPFAPNGVGGVLKGVSAVFFAYIGFDAISTTAEECKNPQRDLPRGMMWAIIICTILYIAIALVLT
GMVKYHELNVGDPLAFVFDKLDLKWMSGIIAVSAVVAMASVLLVFQMGQPRIWMSMSRDGLLPKKFSTVHPKFKTPSFAT
IVTGFVVAIPALFLNLTMVTDLCSIGTLFAFVLVCAGVLVLQNKPEIPRGKFKTPYINSKFILPVLMIAGLYYAFAFNNK
ATMAFINNDPQIYDATSIVTSLDKSESEQVFKYLESIEVNNKTAETSDLEHLLGQYQDDEAKYAEVVKGLPIADSAKYES
GFGLFKHKIPMWIFLFVLVGLAVWAFRRNLSLIPLLGLICCLYMMAELSVWNWIYFTIWLLIGLLIYFTYSRKNSKLNVG
NY

Specific function: Probable Amino-Acid Or Metabolite Transport Protein. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI181337167, Length=448, Percent_Identity=32.8125, Blast_Score=212, Evalue=1e-54,
Organism=Homo sapiens, GI114326544, Length=468, Percent_Identity=30.7692307692308, Blast_Score=209, Evalue=4e-54,
Organism=Homo sapiens, GI114326550, Length=468, Percent_Identity=30.7692307692308, Blast_Score=209, Evalue=4e-54,
Organism=Homo sapiens, GI4507047, Length=466, Percent_Identity=31.9742489270386, Blast_Score=207, Evalue=2e-53,
Organism=Homo sapiens, GI110347453, Length=439, Percent_Identity=30.751708428246, Blast_Score=192, Evalue=1e-48,
Organism=Homo sapiens, GI258614003, Length=502, Percent_Identity=25.6972111553785, Blast_Score=153, Evalue=5e-37,
Organism=Homo sapiens, GI258645169, Length=501, Percent_Identity=25.748502994012, Blast_Score=153, Evalue=5e-37,
Organism=Homo sapiens, GI258614005, Length=502, Percent_Identity=25.6972111553785, Blast_Score=152, Evalue=7e-37,
Organism=Escherichia coli, GI87082023, Length=418, Percent_Identity=24.1626794258373, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI87081869, Length=425, Percent_Identity=21.6470588235294, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI87082250, Length=234, Percent_Identity=27.7777777777778, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87081915, Length=450, Percent_Identity=22.6666666666667, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790653, Length=470, Percent_Identity=21.4893617021277, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1786908, Length=229, Percent_Identity=22.707423580786, Blast_Score=63, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=465, Percent_Identity=30.752688172043, Blast_Score=211, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI17533459, Length=466, Percent_Identity=32.8326180257511, Blast_Score=200, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI17531343, Length=455, Percent_Identity=31.4285714285714, Blast_Score=185, Evalue=5e-47,
Organism=Drosophila melanogaster, GI24667468, Length=662, Percent_Identity=27.4924471299094, Blast_Score=242, Evalue=6e-64,
Organism=Drosophila melanogaster, GI221512776, Length=667, Percent_Identity=28.0359820089955, Blast_Score=241, Evalue=2e-63,
Organism=Drosophila melanogaster, GI24666159, Length=667, Percent_Identity=28.0359820089955, Blast_Score=241, Evalue=2e-63,
Organism=Drosophila melanogaster, GI24668806, Length=452, Percent_Identity=32.3008849557522, Blast_Score=237, Evalue=2e-62,
Organism=Drosophila melanogaster, GI21356285, Length=452, Percent_Identity=32.3008849557522, Blast_Score=237, Evalue=2e-62,
Organism=Drosophila melanogaster, GI24668802, Length=452, Percent_Identity=32.3008849557522, Blast_Score=237, Evalue=2e-62,
Organism=Drosophila melanogaster, GI161077963, Length=467, Percent_Identity=31.9057815845824, Blast_Score=202, Evalue=5e-52,
Organism=Drosophila melanogaster, GI281366235, Length=444, Percent_Identity=29.954954954955, Blast_Score=184, Evalue=2e-46,
Organism=Drosophila melanogaster, GI116007820, Length=444, Percent_Identity=29.954954954955, Blast_Score=184, Evalue=2e-46,
Organism=Drosophila melanogaster, GI116007818, Length=455, Percent_Identity=29.8901098901099, Blast_Score=182, Evalue=7e-46,
Organism=Drosophila melanogaster, GI85725152, Length=455, Percent_Identity=29.8901098901099, Blast_Score=182, Evalue=7e-46,
Organism=Drosophila melanogaster, GI45550968, Length=445, Percent_Identity=22.9213483146067, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI19921172, Length=445, Percent_Identity=22.9213483146067, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI221331183, Length=377, Percent_Identity=21.2201591511936, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17647653, Length=377, Percent_Identity=21.2201591511936, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24664379, Length=377, Percent_Identity=21.2201591511936, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 70700; Mature: 70569

Theoretical pI: Translated: 7.46; Mature: 7.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALSSLFRKKTVQDILKQVAQNETDGHNALGKHLTTKDLTAFGIAAIVGAGIFSTIGKAS
CCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
ADGGPAVIFLFLFTALACSFAAFAYAEFASMVPVSGSAYTYSYVAFGELIAWIIGWALIM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
EYAVGNITVAISWSDYFTGLLQSGGIHLPQWIQMDYLTASNGFKDAEALISAGKSPENLS
HHHHCCEEEEEECHHHHHHHHHCCCCCCCHHHHHHEEECCCCCHHHHHHHHCCCCCHHHH
LALQQAREAWITAPTIGSFHFVTDLPALFIIILITALVYRGMKESRNASNLMVVVKLCVV
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHCCCHHHHHHHHHHHHH
LLVIAVGVFYVDTANWDPFAPNGVGGVLKGVSAVFFAYIGFDAISTTAEECKNPQRDLPR
HHHHHHHHHEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCH
GMMWAIIICTILYIAIALVLTGMVKYHELNVGDPLAFVFDKLDLKWMSGIIAVSAVVAMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVLLVFQMGQPRIWMSMSRDGLLPKKFSTVHPKFKTPSFATIVTGFVVAIPALFLNLTMV
HHHHHHHCCCCCEEEECCCCCCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
TDLCSIGTLFAFVLVCAGVLVLQNKPEIPRGKFKTPYINSKFILPVLMIAGLYYAFAFNN
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEECC
KATMAFINNDPQIYDATSIVTSLDKSESEQVFKYLESIEVNNKTAETSDLEHLLGQYQDD
CEEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCC
EAKYAEVVKGLPIADSAKYESGFGLFKHKIPMWIFLFVLVGLAVWAFRRNLSLIPLLGLI
HHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
CCLYMMAELSVWNWIYFTIWLLIGLLIYFTYSRKNSKLNVGNY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
ALSSLFRKKTVQDILKQVAQNETDGHNALGKHLTTKDLTAFGIAAIVGAGIFSTIGKAS
CHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
ADGGPAVIFLFLFTALACSFAAFAYAEFASMVPVSGSAYTYSYVAFGELIAWIIGWALIM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
EYAVGNITVAISWSDYFTGLLQSGGIHLPQWIQMDYLTASNGFKDAEALISAGKSPENLS
HHHHCCEEEEEECHHHHHHHHHCCCCCCCHHHHHHEEECCCCCHHHHHHHHCCCCCHHHH
LALQQAREAWITAPTIGSFHFVTDLPALFIIILITALVYRGMKESRNASNLMVVVKLCVV
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHCCCHHHHHHHHHHHHH
LLVIAVGVFYVDTANWDPFAPNGVGGVLKGVSAVFFAYIGFDAISTTAEECKNPQRDLPR
HHHHHHHHHEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCH
GMMWAIIICTILYIAIALVLTGMVKYHELNVGDPLAFVFDKLDLKWMSGIIAVSAVVAMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVLLVFQMGQPRIWMSMSRDGLLPKKFSTVHPKFKTPSFATIVTGFVVAIPALFLNLTMV
HHHHHHHCCCCCEEEECCCCCCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
TDLCSIGTLFAFVLVCAGVLVLQNKPEIPRGKFKTPYINSKFILPVLMIAGLYYAFAFNN
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEECC
KATMAFINNDPQIYDATSIVTSLDKSESEQVFKYLESIEVNNKTAETSDLEHLLGQYQDD
CEEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCC
EAKYAEVVKGLPIADSAKYESGFGLFKHKIPMWIFLFVLVGLAVWAFRRNLSLIPLLGLI
HHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
CCLYMMAELSVWNWIYFTIWLLIGLLIYFTYSRKNSKLNVGNY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]