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The map label for this gene is dhbF [H]

Identifier: 146299860

GI number: 146299860

Start: 2534015

End: 2538460

Strand: Direct

Name: dhbF [H]

Synonym: Fjoh_2102

Alternate gene names: 146299860

Gene position: 2534015-2538460 (Clockwise)

Preceding gene: 146299859

Following gene: 146299861

Centisome position: 41.56

GC content: 31.85

Gene sequence:

>4446_bases
ATGAAACTTACACTTCCTCAACAAGATGTTTATTTTGAGCAGCTTATGTATCCTGATGATCCTATTTATAACATAGGGGC
AAAGATTTCCATTGATGGAGATGTTTCCTATGAAATATTAAATCAGGCATACATCGAACTAATTAACCAGCATGATTCTT
ACAGAAGCATTATACAAAAATCTGGAGACCAGGTAACAATTCAAACTGTTGAAAATCATGATTCGGTTTTAGAATATCTG
GATTTTTCCTGTGATGAAAATCCAGATTTAGAAGCAAACCAATTTATGCAGGAAAAATTTCAGGTATCTGTTAAATTAGA
TACCAAAGAATTATTGCACAAATTTATTTTGATAAAAGTAAACGAAAAGCAGCACTATTTATTTTCTGTATATCATCATA
TTATTACAGATGGATGGGGAACATCTCTAATGTTTCAAAGATTAGTGAAAAATTACAATGAAATTTCACTTTCAGGAAAT
GTAACCTCTGTTTATCCTTACTCTTATCAAGATTTTATTTTAGATGATGAAGCCTATTTGTTATCTGAAGATTATGAAAA
TGACAAAAACTATTGGAAAAACAGATTTAAGCAGCTTCCGGAACAATTACTCGAAGTAAAAGAAAATACTGGTAAACCTA
ATCAAAGCAAAAGAAAAGAAATTATTATAAAACGTAACGTTTATAATCAATTAGAGCAGAGAAGTAAAGACTTAGGAGCG
ACAACTTTTCATGTTATTCTTGGTGTTTTATACCTCTATTTTGGAAAAAAACATCAAAATACAGATTTTACAATTGGGCT
TCCAGTCCTGAACAGAGGAAAATCGATATTCAAAAAAACCGTTGGATTATTTATGGGAGTGTCCCCGTTAAGAGTTCAAT
TTGGGTTGGAAGATAATTTTGAAGAACTTATTAAAAATATCAAACAACAGCTTCGTCAGGATTATCGTCATCAAAGATTT
CCTTTAGGAAGATTAGTAAAAGAGCTGGGTTTATTTCAGGAAAATGAAAGGCTTTTTAACATTACATTGTCTTATGAAAA
ACAAAATTATGCAGATCACTTTGTTAATACCATTACAAAGGTAATCCCGCTTTCTCATCATTCTGAGCGAGTAGCTCTGG
CAATCTATATTCGCGAGTTTGATGCATTAGAAGATGTAAAGATAGATTTTGATTACAATGTCAATTATTTTAGTCAGGAA
GATATTTCCCGAGTTGGATCTCATTTTGAAACATTACTTTCTGAAATAATAAAAAGTACAGAAAAACCGCTTTCAGAATA
TGAATATATTACGGCAATTGAGAAAAAACAATTACTGGAAGAATTCAATGCAACAGAATTTAATTGTGATTCAGAAACAA
CATTGCTGGATTCTTTTAAAAAGCAGGCAGCAAAAACTCCAAATAAAATTGCATTAACAGATCAGGAAAAAACATTTACA
TACCAGGAGCTGGATTTGTTTTCGGATAGGGTTGCATTCTTTTTGCAAAAAAAGATTAAAAAAGATGAGCCGGTACCTGT
TGCAGTTCTTATGAATCGTTCTGCAGATCTCGTGGCGACTTTACTAGGTGTTTTGAAATCAGGGAATGCTTATATTCCTT
TAGATCCTTCATTTCCAAAAGATCGTTTAGAATATATTATTGATCACAGCGGTGTAGAACAGGTAATTTCTACAGAAATT
TTAAATCAAAGTATAGGTTTAAACAGGCAGATTATAGACATTGAATTATTGCCAGATGAGGTTTTAGATCAAAAACAAAA
TGCATTAAAAACTGTGCCTTCTGCAAATACGGCGTATATTATATACACTTCAGGATCAACAGGAAATCCTAAAGGAGTTG
CAATTGGTCACAAAGCCCTGCTTAATTTTTTAATCAGCATACAGCAGCAGCCAAAAATTGAAGAACAAGATTATTTGTTT
TCAGTAACAACACAGTCTTTTGATATTTCGATTCTTGAATTTTTTGCTCCATTAATCAGCGGTGCTGCGCTTTATATTGC
AAGTGAAGAACTTTTAGATGATCCTTTTGCAGTTATAACAGCTTTAGAAGACTTAAAACCAACAATAATTCAGGCAACAC
CTAGTTTCTTTCAAATGTTATATAATGCCGGATGGAAAGGAAATAAATCGCTGAAAATTTTATGCGGAGGAGATTTGCTA
AGCGAAACATTGTCTGAAAAATTAAGACAGACCAACGGAGCATTATGGAATATGTACGGACCTACAGAAACAACAATTTG
GTCAAGCTGTAAAAATATTATGCAGGCCAATGAAGCTTCAAATATTGGTAAACCTATCAATAATACCCAGCTATATATTC
TTGATTCATACATGAAGCTGCTTCCTATCGGATCTGCCGGAGCTATTTATATTGGCGGAGATGGTCTGGCACAGGGATAC
TTTAAAAATGAAGAATTGACAAATGAAAAATTCGTTCAAAGTCCGTTTGACCAAAATCAAAAAATATACAATACAGGGGA
TCTGGGACGATGGAACGAAAATGGAGAAATAGAATTCATGGGGCGCAATGATAATCAGGTAAAAATAAGAGGTTATCGAA
TTGAACTTGGTGAAATTGAAGCCAGATTAAATCAGATAAAAAATGTAAAAGCATCTGTTGTTGTTGCCCAAAAATCCAAA
GAACAGGAATCTTTACTTATTGCTTATCTAATTTTTGAAAATGAAGAATTTAACCCTTCGTTTATTGTCAATATTTTAAG
AGAAGAATTACCGGAATACATGATTCCGCATGCCATAATGCAGGTAGATGAATTTCCGCTGACTCCAAATAAAAAAATAG
ACAGAAAAGAGCTTTCATTGCGCAAAATAACAATTGCCAAATCTGAAGTTTCAAACGAAATGCCTGTAACAGCAATTGAG
AAAAGCCTTTACAAATTCTATACAGAAGTATTAGAAATAAAAGCAGAAATTAGTATTACAGATAATTTCTTTGCACTGGG
AGGACATTCCTTAAATGCAGTAAAACTAATAAATCTAATTAATGAACAACTGCATTATAGAATTACCCTAAAAGATGTGT
TTGATTATCCTACAGTTCAAAAACTTGCTAAATATCTTGATAATAAAGAAGTTGTAAAAGATGTAAATATCCAGACTAGT
AATGAAGAGCCCTATTATACAATAACTCCCTCTCAATACAATATTTGGCTGGCATCGCAGCAACAAGAAAAATCGACAGC
TTACAACATGTCGGCAGTATTTAAAATTCAAGGAGAACTGAATAAAGCCCTATTCGATCAGATATTTCATGAAATCCAAA
AGAAACATGAAGTATTGAGAACAAATTTTATTGCGATAGGAGGGATTCCGCACCAGATAATTACAAGTAAAAAAGAAGCG
AATATCTTGATTAATGAATTCTTTTATGATGAAAAACACATAACCGATGCGCTGAATGAGTATATAAATACAGAATTTGA
CCTGGAGAAAGAACCGCTTTTTAGAGTTTCATTTTTTCACGGAAGTGACGGGCAGTCTTACCTTGTTTTTTCGACACATC
ATATTATAATGGATGGCTGGTCTTTGGAGATATTAATTGAAGATTTTGTCAGCAAATACAAAGCCAGAGAAAAACAAGTT
ATACAACAAGAATCAGAATTAAAATTTCAGTTTAAAGATTATGCAGTTTGGCATGAAAAAGAGCTGAAAAGTAATCACGA
AAAAAACTTTGATTTCTGGAAAAACTATCTCAAAGGATATTCATGGAATAAAAATGTGCCTTTTGATTATGAAAATATCG
AAGAAAAAGATTTAAAAGGCAGCCATGATTTTAGGTATGAATCAGTTGAAAATGCACAATTAAAAAGTTTTGTTCATCAG
TATAATGTATCACTTCACACTTTTTTGGTTAATGCATTTAATGTCTTGATTTACAAAATGTATGAGAAAGATGATTTTTG
TGTAGGAACAGTTAATTCCGGAAGAACAAATTCTGAATTGCACAATCAATTAGGAATGTATGTAAAAACATTACCATTAA
GAACACAAATAAATTCAAACCAAACTGTTCTCGAAATCATGAATCAAATGCATCAAAATTTATTATTGATTGATGAGCAT
CAGGATATACCAGCAGTTATACAGTCAAAATTAAGGTTTGATACTTTGTTAGTACTCCAAAATCCATCTTTTGATTATAA
TAACATTTACATAAATAAAGACCTTAATCTGCAGATAGCGCCAATAAAAGAAGCCTACAGCCGATTACCATTGTTGATCA
CTTTTACTGTAAACAGCAAAAAATTGACTGGAAATATAAGTTACTCGGCCTCAAGTTACAGCGCTGAAACAATTGAATTA
ATCACATTAAAATACGAAAAAATAATAGCTGAAATTATTAAAAACCCTAACGTTCCTGTAAGCTCATTAGATATCGAATT
ATCTTTTGAAAAAGAAAGGAAAATTGAGATTGGTTTAAATTTCTAA

Upstream 100 bases:

>100_bases
ATCTGGGCCTGATAAAAACTAAAGTTTAACCGGTAATTATTCTTACAATCTTTATTCCTATAAAGATTGCAGGGAATTCT
CAGCCTAATTTTTTATAAAA

Downstream 100 bases:

>100_bases
ACAACGATTCTAAAAACAACATTAAAAAGAAATATTATGAAATTAAAAGCGACAATTATCCTTATTCTTTTTTTAGTGGT
AAATATTTTGAGCGGTTTAC

Product: amino acid adenylation domain-containing protein

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: NA

Number of amino acids: Translated: 1481; Mature: 1481

Protein sequence:

>1481_residues
MKLTLPQQDVYFEQLMYPDDPIYNIGAKISIDGDVSYEILNQAYIELINQHDSYRSIIQKSGDQVTIQTVENHDSVLEYL
DFSCDENPDLEANQFMQEKFQVSVKLDTKELLHKFILIKVNEKQHYLFSVYHHIITDGWGTSLMFQRLVKNYNEISLSGN
VTSVYPYSYQDFILDDEAYLLSEDYENDKNYWKNRFKQLPEQLLEVKENTGKPNQSKRKEIIIKRNVYNQLEQRSKDLGA
TTFHVILGVLYLYFGKKHQNTDFTIGLPVLNRGKSIFKKTVGLFMGVSPLRVQFGLEDNFEELIKNIKQQLRQDYRHQRF
PLGRLVKELGLFQENERLFNITLSYEKQNYADHFVNTITKVIPLSHHSERVALAIYIREFDALEDVKIDFDYNVNYFSQE
DISRVGSHFETLLSEIIKSTEKPLSEYEYITAIEKKQLLEEFNATEFNCDSETTLLDSFKKQAAKTPNKIALTDQEKTFT
YQELDLFSDRVAFFLQKKIKKDEPVPVAVLMNRSADLVATLLGVLKSGNAYIPLDPSFPKDRLEYIIDHSGVEQVISTEI
LNQSIGLNRQIIDIELLPDEVLDQKQNALKTVPSANTAYIIYTSGSTGNPKGVAIGHKALLNFLISIQQQPKIEEQDYLF
SVTTQSFDISILEFFAPLISGAALYIASEELLDDPFAVITALEDLKPTIIQATPSFFQMLYNAGWKGNKSLKILCGGDLL
SETLSEKLRQTNGALWNMYGPTETTIWSSCKNIMQANEASNIGKPINNTQLYILDSYMKLLPIGSAGAIYIGGDGLAQGY
FKNEELTNEKFVQSPFDQNQKIYNTGDLGRWNENGEIEFMGRNDNQVKIRGYRIELGEIEARLNQIKNVKASVVVAQKSK
EQESLLIAYLIFENEEFNPSFIVNILREELPEYMIPHAIMQVDEFPLTPNKKIDRKELSLRKITIAKSEVSNEMPVTAIE
KSLYKFYTEVLEIKAEISITDNFFALGGHSLNAVKLINLINEQLHYRITLKDVFDYPTVQKLAKYLDNKEVVKDVNIQTS
NEEPYYTITPSQYNIWLASQQQEKSTAYNMSAVFKIQGELNKALFDQIFHEIQKKHEVLRTNFIAIGGIPHQIITSKKEA
NILINEFFYDEKHITDALNEYINTEFDLEKEPLFRVSFFHGSDGQSYLVFSTHHIIMDGWSLEILIEDFVSKYKAREKQV
IQQESELKFQFKDYAVWHEKELKSNHEKNFDFWKNYLKGYSWNKNVPFDYENIEEKDLKGSHDFRYESVENAQLKSFVHQ
YNVSLHTFLVNAFNVLIYKMYEKDDFCVGTVNSGRTNSELHNQLGMYVKTLPLRTQINSNQTVLEIMNQMHQNLLLIDEH
QDIPAVIQSKLRFDTLLVLQNPSFDYNNIYINKDLNLQIAPIKEAYSRLPLLITFTVNSKKLTGNISYSASSYSAETIEL
ITLKYEKIIAEIIKNPNVPVSSLDIELSFEKERKIEIGLNF

Sequences:

>Translated_1481_residues
MKLTLPQQDVYFEQLMYPDDPIYNIGAKISIDGDVSYEILNQAYIELINQHDSYRSIIQKSGDQVTIQTVENHDSVLEYL
DFSCDENPDLEANQFMQEKFQVSVKLDTKELLHKFILIKVNEKQHYLFSVYHHIITDGWGTSLMFQRLVKNYNEISLSGN
VTSVYPYSYQDFILDDEAYLLSEDYENDKNYWKNRFKQLPEQLLEVKENTGKPNQSKRKEIIIKRNVYNQLEQRSKDLGA
TTFHVILGVLYLYFGKKHQNTDFTIGLPVLNRGKSIFKKTVGLFMGVSPLRVQFGLEDNFEELIKNIKQQLRQDYRHQRF
PLGRLVKELGLFQENERLFNITLSYEKQNYADHFVNTITKVIPLSHHSERVALAIYIREFDALEDVKIDFDYNVNYFSQE
DISRVGSHFETLLSEIIKSTEKPLSEYEYITAIEKKQLLEEFNATEFNCDSETTLLDSFKKQAAKTPNKIALTDQEKTFT
YQELDLFSDRVAFFLQKKIKKDEPVPVAVLMNRSADLVATLLGVLKSGNAYIPLDPSFPKDRLEYIIDHSGVEQVISTEI
LNQSIGLNRQIIDIELLPDEVLDQKQNALKTVPSANTAYIIYTSGSTGNPKGVAIGHKALLNFLISIQQQPKIEEQDYLF
SVTTQSFDISILEFFAPLISGAALYIASEELLDDPFAVITALEDLKPTIIQATPSFFQMLYNAGWKGNKSLKILCGGDLL
SETLSEKLRQTNGALWNMYGPTETTIWSSCKNIMQANEASNIGKPINNTQLYILDSYMKLLPIGSAGAIYIGGDGLAQGY
FKNEELTNEKFVQSPFDQNQKIYNTGDLGRWNENGEIEFMGRNDNQVKIRGYRIELGEIEARLNQIKNVKASVVVAQKSK
EQESLLIAYLIFENEEFNPSFIVNILREELPEYMIPHAIMQVDEFPLTPNKKIDRKELSLRKITIAKSEVSNEMPVTAIE
KSLYKFYTEVLEIKAEISITDNFFALGGHSLNAVKLINLINEQLHYRITLKDVFDYPTVQKLAKYLDNKEVVKDVNIQTS
NEEPYYTITPSQYNIWLASQQQEKSTAYNMSAVFKIQGELNKALFDQIFHEIQKKHEVLRTNFIAIGGIPHQIITSKKEA
NILINEFFYDEKHITDALNEYINTEFDLEKEPLFRVSFFHGSDGQSYLVFSTHHIIMDGWSLEILIEDFVSKYKAREKQV
IQQESELKFQFKDYAVWHEKELKSNHEKNFDFWKNYLKGYSWNKNVPFDYENIEEKDLKGSHDFRYESVENAQLKSFVHQ
YNVSLHTFLVNAFNVLIYKMYEKDDFCVGTVNSGRTNSELHNQLGMYVKTLPLRTQINSNQTVLEIMNQMHQNLLLIDEH
QDIPAVIQSKLRFDTLLVLQNPSFDYNNIYINKDLNLQIAPIKEAYSRLPLLITFTVNSKKLTGNISYSASSYSAETIEL
ITLKYEKIIAEIIKNPNVPVSSLDIELSFEKERKIEIGLNF
>Mature_1481_residues
MKLTLPQQDVYFEQLMYPDDPIYNIGAKISIDGDVSYEILNQAYIELINQHDSYRSIIQKSGDQVTIQTVENHDSVLEYL
DFSCDENPDLEANQFMQEKFQVSVKLDTKELLHKFILIKVNEKQHYLFSVYHHIITDGWGTSLMFQRLVKNYNEISLSGN
VTSVYPYSYQDFILDDEAYLLSEDYENDKNYWKNRFKQLPEQLLEVKENTGKPNQSKRKEIIIKRNVYNQLEQRSKDLGA
TTFHVILGVLYLYFGKKHQNTDFTIGLPVLNRGKSIFKKTVGLFMGVSPLRVQFGLEDNFEELIKNIKQQLRQDYRHQRF
PLGRLVKELGLFQENERLFNITLSYEKQNYADHFVNTITKVIPLSHHSERVALAIYIREFDALEDVKIDFDYNVNYFSQE
DISRVGSHFETLLSEIIKSTEKPLSEYEYITAIEKKQLLEEFNATEFNCDSETTLLDSFKKQAAKTPNKIALTDQEKTFT
YQELDLFSDRVAFFLQKKIKKDEPVPVAVLMNRSADLVATLLGVLKSGNAYIPLDPSFPKDRLEYIIDHSGVEQVISTEI
LNQSIGLNRQIIDIELLPDEVLDQKQNALKTVPSANTAYIIYTSGSTGNPKGVAIGHKALLNFLISIQQQPKIEEQDYLF
SVTTQSFDISILEFFAPLISGAALYIASEELLDDPFAVITALEDLKPTIIQATPSFFQMLYNAGWKGNKSLKILCGGDLL
SETLSEKLRQTNGALWNMYGPTETTIWSSCKNIMQANEASNIGKPINNTQLYILDSYMKLLPIGSAGAIYIGGDGLAQGY
FKNEELTNEKFVQSPFDQNQKIYNTGDLGRWNENGEIEFMGRNDNQVKIRGYRIELGEIEARLNQIKNVKASVVVAQKSK
EQESLLIAYLIFENEEFNPSFIVNILREELPEYMIPHAIMQVDEFPLTPNKKIDRKELSLRKITIAKSEVSNEMPVTAIE
KSLYKFYTEVLEIKAEISITDNFFALGGHSLNAVKLINLINEQLHYRITLKDVFDYPTVQKLAKYLDNKEVVKDVNIQTS
NEEPYYTITPSQYNIWLASQQQEKSTAYNMSAVFKIQGELNKALFDQIFHEIQKKHEVLRTNFIAIGGIPHQIITSKKEA
NILINEFFYDEKHITDALNEYINTEFDLEKEPLFRVSFFHGSDGQSYLVFSTHHIIMDGWSLEILIEDFVSKYKAREKQV
IQQESELKFQFKDYAVWHEKELKSNHEKNFDFWKNYLKGYSWNKNVPFDYENIEEKDLKGSHDFRYESVENAQLKSFVHQ
YNVSLHTFLVNAFNVLIYKMYEKDDFCVGTVNSGRTNSELHNQLGMYVKTLPLRTQINSNQTVLEIMNQMHQNLLLIDEH
QDIPAVIQSKLRFDTLLVLQNPSFDYNNIYINKDLNLQIAPIKEAYSRLPLLITFTVNSKKLTGNISYSASSYSAETIEL
ITLKYEKIIAEIIKNPNVPVSSLDIELSFEKERKIEIGLNF

Specific function: Specifically adenylates threonine and glycine, and loads them onto their corresponding peptidyl carrier domains [H]

COG id: COG1020

COG function: function code Q; Non-ribosomal peptide synthetase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 acyl carrier domain [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=429, Percent_Identity=25.6410256410256, Blast_Score=109, Evalue=2e-23,
Organism=Homo sapiens, GI38505220, Length=568, Percent_Identity=22.1830985915493, Blast_Score=92, Evalue=3e-18,
Organism=Homo sapiens, GI42544132, Length=565, Percent_Identity=22.3008849557522, Blast_Score=91, Evalue=8e-18,
Organism=Homo sapiens, GI157311624, Length=503, Percent_Identity=22.2664015904573, Blast_Score=78, Evalue=8e-14,
Organism=Homo sapiens, GI157311622, Length=503, Percent_Identity=22.2664015904573, Blast_Score=78, Evalue=8e-14,
Organism=Homo sapiens, GI58082049, Length=503, Percent_Identity=22.0675944333996, Blast_Score=76, Evalue=2e-13,
Organism=Homo sapiens, GI115511026, Length=549, Percent_Identity=21.4936247723133, Blast_Score=74, Evalue=7e-13,
Organism=Homo sapiens, GI122937307, Length=553, Percent_Identity=22.0614828209765, Blast_Score=72, Evalue=5e-12,
Organism=Escherichia coli, GI1786801, Length=1040, Percent_Identity=28.1730769230769, Blast_Score=372, Evalue=1e-104,
Organism=Escherichia coli, GI145693145, Length=543, Percent_Identity=22.2836095764273, Blast_Score=102, Evalue=1e-22,
Organism=Escherichia coli, GI1788107, Length=566, Percent_Identity=21.5547703180212, Blast_Score=97, Evalue=7e-21,
Organism=Escherichia coli, GI1786810, Length=526, Percent_Identity=24.5247148288973, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17556356, Length=522, Percent_Identity=28.735632183908, Blast_Score=154, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI17550940, Length=1064, Percent_Identity=21.5225563909774, Blast_Score=133, Evalue=9e-31,
Organism=Caenorhabditis elegans, GI17558820, Length=490, Percent_Identity=22.2448979591837, Blast_Score=106, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI32563687, Length=481, Percent_Identity=23.2848232848233, Blast_Score=105, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI32564420, Length=410, Percent_Identity=26.5853658536585, Blast_Score=93, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI32564422, Length=410, Percent_Identity=26.5853658536585, Blast_Score=93, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71994703, Length=368, Percent_Identity=22.8260869565217, Blast_Score=77, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71994690, Length=368, Percent_Identity=22.8260869565217, Blast_Score=77, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71994694, Length=368, Percent_Identity=22.8260869565217, Blast_Score=77, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17560308, Length=391, Percent_Identity=21.227621483376, Blast_Score=72, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17538037, Length=437, Percent_Identity=21.7391304347826, Blast_Score=72, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319591, Length=752, Percent_Identity=26.3297872340426, Blast_Score=230, Evalue=1e-60,
Organism=Drosophila melanogaster, GI24648676, Length=624, Percent_Identity=27.2435897435897, Blast_Score=202, Evalue=2e-51,
Organism=Drosophila melanogaster, GI24581924, Length=362, Percent_Identity=25.1381215469613, Blast_Score=90, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24582852, Length=524, Percent_Identity=21.5648854961832, Blast_Score=85, Evalue=4e-16,
Organism=Drosophila melanogaster, GI21355181, Length=487, Percent_Identity=22.5872689938398, Blast_Score=74, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24656500, Length=492, Percent_Identity=22.5609756097561, Blast_Score=72, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding; PF00975 Thioesterase [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 171128; Mature: 171128

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTLPQQDVYFEQLMYPDDPIYNIGAKISIDGDVSYEILNQAYIELINQHDSYRSIIQK
CCCCCCCHHHHHHHHCCCCCCCEECCEEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHC
SGDQVTIQTVENHDSVLEYLDFSCDENPDLEANQFMQEKFQVSVKLDTKELLHKFILIKV
CCCEEEEEEECCHHHHHHHHCCCCCCCCCCCHHHHHHHHHEEEEEECHHHHHHHEEEEEE
NEKQHYLFSVYHHIITDGWGTSLMFQRLVKNYNEISLSGNVTSVYPYSYQDFILDDEAYL
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEECCCEEEECCCCCCCEEECCCCEE
LSEDYENDKNYWKNRFKQLPEQLLEVKENTGKPNQSKRKEIIIKRNVYNQLEQRSKDLGA
ECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHEEEEHHHHHHHHHHHHHCCC
TTFHVILGVLYLYFGKKHQNTDFTIGLPVLNRGKSIFKKTVGLFMGVSPLRVQFGLEDNF
HHHHHHHHHHHHHHCCCCCCCCEEEECCCHHCCHHHHHHHHHHHHCCCCEEEEECCCCCH
EELIKNIKQQLRQDYRHQRFPLGRLVKELGLFQENERLFNITLSYEKQNYADHFVNTITK
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEEEEEEECCCCHHHHHHHHHHH
VIPLSHHSERVALAIYIREFDALEDVKIDFDYNVNYFSQEDISRVGSHFETLLSEIIKST
HHCCCCCCCEEEEEEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
EKPLSEYEYITAIEKKQLLEEFNATEFNCDSETTLLDSFKKQAAKTPNKIALTDQEKTFT
CCHHHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHCCCCEEEEECCCCCEE
YQELDLFSDRVAFFLQKKIKKDEPVPVAVLMNRSADLVATLLGVLKSGNAYIPLDPSFPK
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEECCCCCCH
DRLEYIIDHSGVEQVISTEILNQSIGLNRQIIDIELLPDEVLDQKQNALKTVPSANTAYI
HHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHCCCCCCEEEE
IYTSGSTGNPKGVAIGHKALLNFLISIQQQPKIEEQDYLFSVTTQSFDISILEFFAPLIS
EEECCCCCCCCCEEEHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHC
GAALYIASEELLDDPFAVITALEDLKPTIIQATPSFFQMLYNAGWKGNKSLKILCGGDLL
CCEEEEECHHHHCCHHHHHHHHHHCCCCEEECCHHHHHHHHHCCCCCCCEEEEEECCHHH
SETLSEKLRQTNGALWNMYGPTETTIWSSCKNIMQANEASNIGKPINNTQLYILDSYMKL
HHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHCCHHCCCCCCCCCEEEEEEHHHHH
LPIGSAGAIYIGGDGLAQGYFKNEELTNEKFVQSPFDQNQKIYNTGDLGRWNENGEIEFM
EECCCCCEEEECCCCHHCCCCCCCCCCCHHHHCCCCCCCCCEEECCCCCCCCCCCCEEEE
GRNDNQVKIRGYRIELGEIEARLNQIKNVKASVVVAQKSKEQESLLIAYLIFENEEFNPS
ECCCCEEEEEEEEEEHHHHHHHHHHHHCCCEEEEEEECCCCCCCEEEEEEEEECCCCCHH
FIVNILREELPEYMIPHAIMQVDEFPLTPNKKIDRKELSLRKITIAKSEVSNEMPVTAIE
HHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCHHHHHHEEEEEEHHHCCCCCCHHHHH
KSLYKFYTEVLEIKAEISITDNFFALGGHSLNAVKLINLINEQLHYRITLKDVFDYPTVQ
HHHHHHHHHHHHHHEEEEEECCEEEECCCCCHHHHHHHHHHHHHEEEEEEHHHHCCCHHH
KLAKYLDNKEVVKDVNIQTSNEEPYYTITPSQYNIWLASQQQEKSTAYNMSAVFKIQGEL
HHHHHCCCHHHHHCCCCEECCCCCEEEECCCCEEEEEECCCHHHHHHCCEEEEEEECCHH
NKALFDQIFHEIQKKHEVLRTNFIAIGGIPHQIITSKKEANILINEFFYDEKHITDALNE
HHHHHHHHHHHHHHHHHHHHHCEEEECCCCHHHHCCCCCCCEEEHHHHCCHHHHHHHHHH
YINTEFDLEKEPLFRVSFFHGSDGQSYLVFSTHHIIMDGWSLEILIEDFVSKYKAREKQV
HHCCCCCCCCCCEEEEEEEECCCCCEEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHH
IQQESELKFQFKDYAVWHEKELKSNHEKNFDFWKNYLKGYSWNKNVPFDYENIEEKDLKG
HHHHHHCEEEEEHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHCCCC
SHDFRYESVENAQLKSFVHQYNVSLHTFLVNAFNVLIYKMYEKDDFCVGTVNSGRTNSEL
CCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHEEEECCCCCEEECCCCCCCCHHH
HNQLGMYVKTLPLRTQINSNQTVLEIMNQMHQNLLLIDEHQDIPAVIQSKLRFDTLLVLQ
HHHHHHHHEECCEEEECCCCHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHCCEEEEEEE
NPSFDYNNIYINKDLNLQIAPIKEAYSRLPLLITFTVNSKKLTGNISYSASSYSAETIEL
CCCCCCCEEEECCCCCEEEEEHHHHHCCCCEEEEEEECCEEEEEEEEECCCCCCCCEEEE
ITLKYEKIIAEIIKNPNVPVSSLDIELSFEKERKIEIGLNF
EEHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCEEEEECCC
>Mature Secondary Structure
MKLTLPQQDVYFEQLMYPDDPIYNIGAKISIDGDVSYEILNQAYIELINQHDSYRSIIQK
CCCCCCCHHHHHHHHCCCCCCCEECCEEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHC
SGDQVTIQTVENHDSVLEYLDFSCDENPDLEANQFMQEKFQVSVKLDTKELLHKFILIKV
CCCEEEEEEECCHHHHHHHHCCCCCCCCCCCHHHHHHHHHEEEEEECHHHHHHHEEEEEE
NEKQHYLFSVYHHIITDGWGTSLMFQRLVKNYNEISLSGNVTSVYPYSYQDFILDDEAYL
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEECCCEEEECCCCCCCEEECCCCEE
LSEDYENDKNYWKNRFKQLPEQLLEVKENTGKPNQSKRKEIIIKRNVYNQLEQRSKDLGA
ECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHEEEEHHHHHHHHHHHHHCCC
TTFHVILGVLYLYFGKKHQNTDFTIGLPVLNRGKSIFKKTVGLFMGVSPLRVQFGLEDNF
HHHHHHHHHHHHHHCCCCCCCCEEEECCCHHCCHHHHHHHHHHHHCCCCEEEEECCCCCH
EELIKNIKQQLRQDYRHQRFPLGRLVKELGLFQENERLFNITLSYEKQNYADHFVNTITK
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEEEEEEECCCCHHHHHHHHHHH
VIPLSHHSERVALAIYIREFDALEDVKIDFDYNVNYFSQEDISRVGSHFETLLSEIIKST
HHCCCCCCCEEEEEEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
EKPLSEYEYITAIEKKQLLEEFNATEFNCDSETTLLDSFKKQAAKTPNKIALTDQEKTFT
CCHHHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHCCCCEEEEECCCCCEE
YQELDLFSDRVAFFLQKKIKKDEPVPVAVLMNRSADLVATLLGVLKSGNAYIPLDPSFPK
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEECCCCCCH
DRLEYIIDHSGVEQVISTEILNQSIGLNRQIIDIELLPDEVLDQKQNALKTVPSANTAYI
HHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHCCCCCCEEEE
IYTSGSTGNPKGVAIGHKALLNFLISIQQQPKIEEQDYLFSVTTQSFDISILEFFAPLIS
EEECCCCCCCCCEEEHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHC
GAALYIASEELLDDPFAVITALEDLKPTIIQATPSFFQMLYNAGWKGNKSLKILCGGDLL
CCEEEEECHHHHCCHHHHHHHHHHCCCCEEECCHHHHHHHHHCCCCCCCEEEEEECCHHH
SETLSEKLRQTNGALWNMYGPTETTIWSSCKNIMQANEASNIGKPINNTQLYILDSYMKL
HHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHCCHHCCCCCCCCCEEEEEEHHHHH
LPIGSAGAIYIGGDGLAQGYFKNEELTNEKFVQSPFDQNQKIYNTGDLGRWNENGEIEFM
EECCCCCEEEECCCCHHCCCCCCCCCCCHHHHCCCCCCCCCEEECCCCCCCCCCCCEEEE
GRNDNQVKIRGYRIELGEIEARLNQIKNVKASVVVAQKSKEQESLLIAYLIFENEEFNPS
ECCCCEEEEEEEEEEHHHHHHHHHHHHCCCEEEEEEECCCCCCCEEEEEEEEECCCCCHH
FIVNILREELPEYMIPHAIMQVDEFPLTPNKKIDRKELSLRKITIAKSEVSNEMPVTAIE
HHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCHHHHHHEEEEEEHHHCCCCCCHHHHH
KSLYKFYTEVLEIKAEISITDNFFALGGHSLNAVKLINLINEQLHYRITLKDVFDYPTVQ
HHHHHHHHHHHHHHEEEEEECCEEEECCCCCHHHHHHHHHHHHHEEEEEEHHHHCCCHHH
KLAKYLDNKEVVKDVNIQTSNEEPYYTITPSQYNIWLASQQQEKSTAYNMSAVFKIQGEL
HHHHHCCCHHHHHCCCCEECCCCCEEEECCCCEEEEEECCCHHHHHHCCEEEEEEECCHH
NKALFDQIFHEIQKKHEVLRTNFIAIGGIPHQIITSKKEANILINEFFYDEKHITDALNE
HHHHHHHHHHHHHHHHHHHHHCEEEECCCCHHHHCCCCCCCEEEHHHHCCHHHHHHHHHH
YINTEFDLEKEPLFRVSFFHGSDGQSYLVFSTHHIIMDGWSLEILIEDFVSKYKAREKQV
HHCCCCCCCCCCEEEEEEEECCCCCEEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHH
IQQESELKFQFKDYAVWHEKELKSNHEKNFDFWKNYLKGYSWNKNVPFDYENIEEKDLKG
HHHHHHCEEEEEHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHCCCC
SHDFRYESVENAQLKSFVHQYNVSLHTFLVNAFNVLIYKMYEKDDFCVGTVNSGRTNSEL
CCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHEEEECCCCCEEECCCCCCCCHHH
HNQLGMYVKTLPLRTQINSNQTVLEIMNQMHQNLLLIDEHQDIPAVIQSKLRFDTLLVLQ
HHHHHHHHEECCEEEECCCCHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHCCEEEEEEE
NPSFDYNNIYINKDLNLQIAPIKEAYSRLPLLITFTVNSKKLTGNISYSASSYSAETIEL
CCCCCCCEEEECCCCCEEEEEHHHHHCCCCEEEEEEECCEEEEEEEEECCCCCCCCEEEE
ITLKYEKIIAEIIKNPNVPVSSLDIELSFEKERKIEIGLNF
EEHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11112781; 9384377; 10568751; 8550523 [H]