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The map label for this gene is syrD [H]

Identifier: 146299859

GI number: 146299859

Start: 2532301

End: 2533926

Strand: Direct

Name: syrD [H]

Synonym: Fjoh_2101

Alternate gene names: 146299859

Gene position: 2532301-2533926 (Clockwise)

Preceding gene: 146299858

Following gene: 146299860

Centisome position: 41.53

GC content: 30.32

Gene sequence:

>1626_bases
ATGTTAAAAATAAAAAAACGAGAAATTTTTTATCTCCTTTTATACGCTGTGCCAAACACCTTATTAACATTCTCGATTGT
ATATATAATCAATAATGTAATGGCAGGAAACAAAGCTTTCCTTACTGACTATATGGGAATTGTGTTTGTGTCTATTCTTG
TATATACGTATTTATTAAATGTTATTTTTCAAAAAAAGCTCAATAAGTTTTCATTTAATATGCTTTATGAAAATGAAAAG
AAAATTTTCAAACAAATATTAAGCGTTCCATTGCTAAAACTGGAACAATACGGATCGCAGAGATTTTATACGGTTGTCGA
AGATTTAAGAACCTTTTCTTTACTGCCTTATACTGTTACACATACAATTAATTCGCTATTAATGCTTATCCTTTGTTTAA
TCTATATGTTTACACTTTCGCTGGTATCTGCCTTAATAGTAGTAAGCTTGATTGTAATGGTAGGAGCCTGCTATTTTATT
GTAATGAATGCAATGTCTAAAAGAGTAAATCAATTAAGAGAATACAATGATGGATATTACAAATCAGTAGATGATGTTAT
ACGAGGTTTTAAGGAGTTAAAAGTTAGTTTTTTAAGAAGAGATAACTTACTGAACAAATTTATTATTCCAAACAGAGATG
AAGCAATGAATCTTGATTTTAGTATAAATTATGTTTTTCTTTCTATTAACCTAATAAGCCAATACGGATTGTATTTTGTT
GTATCTGTAATTTTATTTGTACTGCCGGCACTTGATCTCCTTTCAAGAGAAGATGTTATTTCGTATGTCGTAATTATTTT
ATTTATCTCTGGGCCTATAAACAATATCATCAACTTACAGCAGCTTTATACTCGATTTTTTGTTGCCAATACAAGAATCT
CGAATTTTATAAAAGATTTTGAAGTTATTGAAGAAACGGCACCTAAAAATGAAACCCTGAATGATTTTCAATCCCTGAAT
TTTAGCGATGTTGAATTTACTTATCCAAGCAAAGATGAAGATTCATCTTTTCAGTTAGGACCAATAAGCTTAAACATTCA
AAAAGGCGAAACCATCTTTATAGTGGGTGGAAATGGGTCTGGAAAAAGCACCTTTATAAACCTGCTTACTGGACTTTACA
AACCTACAGAAGGAAAAATTATAATAGATGACAAAAGCGACAGGGGAGAAAATATACAAGACCTTATTGCAGCCGTATTT
ACAGATAATCATTTGTTTTCTAAAAATTACGACGATTATACCTTAGAGAATAATAAAGATTATGTCGAATTATTAAAAAC
AATGGAGATGGATAGAATCATTACAGATGATAAAGATTCGTCTATAAGAAGAAAATTCTCTAAAGGTCAAAGTAAACGAA
TGTCGTTGATTTTTAATTTGTTAGAGAAAAAACCCGTAATGGTTTTAGACGAATGGGCCGCAGATCAGGATCCGCATTTT
AGAAAATATTTCTATGAATTTCTTTTGCCAAAATTTAAAGAAGAAGGCAAAACGATTATTGCAGTTACACATGATGATGC
CTATTTTCATTTGGCAGACAGAATCATAAAATTTGATTATGGCAATATTGTCAAAGAAATTAAAACTACCAGCAAAGAAG
AATTGGCCGAGAATATCTGGGCCTGA

Upstream 100 bases:

>100_bases
TTGGAAGCAGCATTGAATCTTCAGAAATCGAAAAAATAATCTACCAGCTCGACGCAGAAAGGGTAGAATTAAAAATGAAA
TTAACGTAACCTTACTTATC

Downstream 100 bases:

>100_bases
TAAAAACTAAAGTTTAACCGGTAATTATTCTTACAATCTTTATTCCTATAAAGATTGCAGGGAATTCTCAGCCTAATTTT
TTATAAAAATGAAACTTACA

Product: cyclic peptide transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 541; Mature: 541

Protein sequence:

>541_residues
MLKIKKREIFYLLLYAVPNTLLTFSIVYIINNVMAGNKAFLTDYMGIVFVSILVYTYLLNVIFQKKLNKFSFNMLYENEK
KIFKQILSVPLLKLEQYGSQRFYTVVEDLRTFSLLPYTVTHTINSLLMLILCLIYMFTLSLVSALIVVSLIVMVGACYFI
VMNAMSKRVNQLREYNDGYYKSVDDVIRGFKELKVSFLRRDNLLNKFIIPNRDEAMNLDFSINYVFLSINLISQYGLYFV
VSVILFVLPALDLLSREDVISYVVIILFISGPINNIINLQQLYTRFFVANTRISNFIKDFEVIEETAPKNETLNDFQSLN
FSDVEFTYPSKDEDSSFQLGPISLNIQKGETIFIVGGNGSGKSTFINLLTGLYKPTEGKIIIDDKSDRGENIQDLIAAVF
TDNHLFSKNYDDYTLENNKDYVELLKTMEMDRIITDDKDSSIRRKFSKGQSKRMSLIFNLLEKKPVMVLDEWAADQDPHF
RKYFYEFLLPKFKEEGKTIIAVTHDDAYFHLADRIIKFDYGNIVKEIKTTSKEELAENIWA

Sequences:

>Translated_541_residues
MLKIKKREIFYLLLYAVPNTLLTFSIVYIINNVMAGNKAFLTDYMGIVFVSILVYTYLLNVIFQKKLNKFSFNMLYENEK
KIFKQILSVPLLKLEQYGSQRFYTVVEDLRTFSLLPYTVTHTINSLLMLILCLIYMFTLSLVSALIVVSLIVMVGACYFI
VMNAMSKRVNQLREYNDGYYKSVDDVIRGFKELKVSFLRRDNLLNKFIIPNRDEAMNLDFSINYVFLSINLISQYGLYFV
VSVILFVLPALDLLSREDVISYVVIILFISGPINNIINLQQLYTRFFVANTRISNFIKDFEVIEETAPKNETLNDFQSLN
FSDVEFTYPSKDEDSSFQLGPISLNIQKGETIFIVGGNGSGKSTFINLLTGLYKPTEGKIIIDDKSDRGENIQDLIAAVF
TDNHLFSKNYDDYTLENNKDYVELLKTMEMDRIITDDKDSSIRRKFSKGQSKRMSLIFNLLEKKPVMVLDEWAADQDPHF
RKYFYEFLLPKFKEEGKTIIAVTHDDAYFHLADRIIKFDYGNIVKEIKTTSKEELAENIWA
>Mature_541_residues
MLKIKKREIFYLLLYAVPNTLLTFSIVYIINNVMAGNKAFLTDYMGIVFVSILVYTYLLNVIFQKKLNKFSFNMLYENEK
KIFKQILSVPLLKLEQYGSQRFYTVVEDLRTFSLLPYTVTHTINSLLMLILCLIYMFTLSLVSALIVVSLIVMVGACYFI
VMNAMSKRVNQLREYNDGYYKSVDDVIRGFKELKVSFLRRDNLLNKFIIPNRDEAMNLDFSINYVFLSINLISQYGLYFV
VSVILFVLPALDLLSREDVISYVVIILFISGPINNIINLQQLYTRFFVANTRISNFIKDFEVIEETAPKNETLNDFQSLN
FSDVEFTYPSKDEDSSFQLGPISLNIQKGETIFIVGGNGSGKSTFINLLTGLYKPTEGKIIIDDKSDRGENIQDLIAAVF
TDNHLFSKNYDDYTLENNKDYVELLKTMEMDRIITDDKDSSIRRKFSKGQSKRMSLIFNLLEKKPVMVLDEWAADQDPHF
RKYFYEFLLPKFKEEGKTIIAVTHDDAYFHLADRIIKFDYGNIVKEIKTTSKEELAENIWA

Specific function: ATP-driven efflux pump necessary for the secretion of syringomycin. May specifically bind syringomycin and translocate it to the periplasmic space. SyrD is also required for full expression of the syrB gene [H]

COG id: COG4615

COG function: function code QP; ABC-type siderophore export system, fused ATPase and permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI42741659, Length=436, Percent_Identity=23.8532110091743, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI21536378, Length=266, Percent_Identity=26.6917293233083, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI45446740, Length=206, Percent_Identity=30.5825242718447, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI47078218, Length=206, Percent_Identity=30.5825242718447, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI4505771, Length=430, Percent_Identity=22.7906976744186, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI9961252, Length=232, Percent_Identity=27.5862068965517, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI9961250, Length=222, Percent_Identity=28.8288288288288, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI255708477, Length=241, Percent_Identity=27.8008298755187, Blast_Score=77, Evalue=6e-14,
Organism=Homo sapiens, GI148612844, Length=241, Percent_Identity=27.8008298755187, Blast_Score=76, Evalue=9e-14,
Organism=Homo sapiens, GI4557481, Length=524, Percent_Identity=20.9923664122137, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI171184400, Length=244, Percent_Identity=28.6885245901639, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI9955970, Length=415, Percent_Identity=20.9638554216867, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1788540, Length=467, Percent_Identity=30.406852248394, Blast_Score=228, Evalue=6e-61,
Organism=Escherichia coli, GI1787112, Length=248, Percent_Identity=30.6451612903226, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1787105, Length=226, Percent_Identity=29.646017699115, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1787143, Length=519, Percent_Identity=20.8092485549133, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1787547, Length=206, Percent_Identity=26.6990291262136, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789672, Length=199, Percent_Identity=27.6381909547739, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787029, Length=237, Percent_Identity=27.8481012658228, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87081709, Length=197, Percent_Identity=27.9187817258883, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786398, Length=199, Percent_Identity=24.1206030150754, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17565938, Length=238, Percent_Identity=29.8319327731092, Blast_Score=88, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17569081, Length=415, Percent_Identity=25.0602409638554, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI193202349, Length=231, Percent_Identity=30.7359307359307, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71984940, Length=335, Percent_Identity=26.5671641791045, Blast_Score=85, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI25146765, Length=427, Percent_Identity=23.1850117096019, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71992070, Length=427, Percent_Identity=23.1850117096019, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71992066, Length=427, Percent_Identity=23.1850117096019, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI86564969, Length=427, Percent_Identity=23.1850117096019, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI193209708, Length=230, Percent_Identity=27.3913043478261, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17543740, Length=235, Percent_Identity=28.936170212766, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI115533592, Length=431, Percent_Identity=22.5058004640371, Blast_Score=76, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17567265, Length=231, Percent_Identity=28.1385281385281, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI115535101, Length=231, Percent_Identity=26.4069264069264, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17558664, Length=296, Percent_Identity=25.3378378378378, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193211015, Length=249, Percent_Identity=28.5140562248996, Blast_Score=74, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI193211017, Length=249, Percent_Identity=28.5140562248996, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71992290, Length=222, Percent_Identity=25.2252252252252, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17567269, Length=237, Percent_Identity=28.2700421940928, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17511077, Length=432, Percent_Identity=23.6111111111111, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI71996809, Length=249, Percent_Identity=28.1124497991968, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI212646699, Length=233, Percent_Identity=28.3261802575107, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25146777, Length=246, Percent_Identity=27.6422764227642, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193208177, Length=318, Percent_Identity=24.5283018867925, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17569143, Length=258, Percent_Identity=25.5813953488372, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17541710, Length=572, Percent_Identity=20.4545454545455, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17551700, Length=252, Percent_Identity=28.968253968254, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17551702, Length=252, Percent_Identity=28.968253968254, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322640, Length=316, Percent_Identity=26.2658227848101, Blast_Score=77, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24659289, Length=512, Percent_Identity=23.046875, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17136662, Length=275, Percent_Identity=26.5454545454545, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI85726357, Length=348, Percent_Identity=25.5747126436782, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24648279, Length=256, Percent_Identity=26.953125, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI23397593, Length=228, Percent_Identity=26.7543859649123, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017940
- InterPro:   IPR001140
- InterPro:   IPR011527
- InterPro:   IPR003593
- InterPro:   IPR005898 [H]

Pfam domain/function: PF00664 ABC_membrane; PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 62802; Mature: 62802

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS50893 ABC_TRANSPORTER_2 ; PS50929 ABC_TM1F

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKIKKREIFYLLLYAVPNTLLTFSIVYIINNVMAGNKAFLTDYMGIVFVSILVYTYLLN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
VIFQKKLNKFSFNMLYENEKKIFKQILSVPLLKLEQYGSQRFYTVVEDLRTFSLLPYTVT
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHH
HTINSLLMLILCLIYMFTLSLVSALIVVSLIVMVGACYFIVMNAMSKRVNQLREYNDGYY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
KSVDDVIRGFKELKVSFLRRDNLLNKFIIPNRDEAMNLDFSINYVFLSINLISQYGLYFV
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECEEEEEEEEEEEHHHHHHHHHHH
VSVILFVLPALDLLSREDVISYVVIILFISGPINNIINLQQLYTRFFVANTRISNFIKDF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVIEETAPKNETLNDFQSLNFSDVEFTYPSKDEDSSFQLGPISLNIQKGETIFIVGGNGS
HHHHHCCCCCCCHHHHHCCCCCCEEEECCCCCCCCCEEECCEEEEEECCCEEEEEECCCC
GKSTFINLLTGLYKPTEGKIIIDDKSDRGENIQDLIAAVFTDNHLFSKNYDDYTLENNKD
CHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCEECCCCCCCCCCCCCH
YVELLKTMEMDRIITDDKDSSIRRKFSKGQSKRMSLIFNLLEKKPVMVLDEWAADQDPHF
HHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCHH
RKYFYEFLLPKFKEEGKTIIAVTHDDAYFHLADRIIKFDYGNIVKEIKTTSKEELAENIW
HHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHC
A
C
>Mature Secondary Structure
MLKIKKREIFYLLLYAVPNTLLTFSIVYIINNVMAGNKAFLTDYMGIVFVSILVYTYLLN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
VIFQKKLNKFSFNMLYENEKKIFKQILSVPLLKLEQYGSQRFYTVVEDLRTFSLLPYTVT
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHH
HTINSLLMLILCLIYMFTLSLVSALIVVSLIVMVGACYFIVMNAMSKRVNQLREYNDGYY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
KSVDDVIRGFKELKVSFLRRDNLLNKFIIPNRDEAMNLDFSINYVFLSINLISQYGLYFV
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECEEEEEEEEEEEHHHHHHHHHHH
VSVILFVLPALDLLSREDVISYVVIILFISGPINNIINLQQLYTRFFVANTRISNFIKDF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVIEETAPKNETLNDFQSLNFSDVEFTYPSKDEDSSFQLGPISLNIQKGETIFIVGGNGS
HHHHHCCCCCCCHHHHHCCCCCCEEEECCCCCCCCCEEECCEEEEEECCCEEEEEECCCC
GKSTFINLLTGLYKPTEGKIIIDDKSDRGENIQDLIAAVFTDNHLFSKNYDDYTLENNKD
CHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCEECCCCCCCCCCCCCH
YVELLKTMEMDRIITDDKDSSIRRKFSKGQSKRMSLIFNLLEKKPVMVLDEWAADQDPHF
HHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCHH
RKYFYEFLLPKFKEEGKTIIAVTHDDAYFHLADRIIKFDYGNIVKEIKTTSKEELAENIW
HHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8231810 [H]