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The map label for this gene is csd [H]

Identifier: 146299774

GI number: 146299774

Start: 2355880

End: 2357388

Strand: Direct

Name: csd [H]

Synonym: Fjoh_2014

Alternate gene names: 146299774

Gene position: 2355880-2357388 (Clockwise)

Preceding gene: 146299773

Following gene: 146299777

Centisome position: 38.64

GC content: 38.24

Gene sequence:

>1509_bases
ATGATAAATGAAATGGATACTATTTTGAATACAAAACCAAGCGAACTCGAAAACTATTTTTCTGAATTTAGAGAAAATAC
AATTGGAGTCAATCACAGTTTCGAGTCGATTTACGGCCCGCAGAATATTCTGTATGCAGACTGGATTGCCAGTGGAAGAT
TATATTTCCCGATTGAAGATATTATGCTTCGAAAAATTGGTCCAATGATCGCCAATACGCACTCTTTTTCCAGCCAGACC
GGAAAAGCTTCGACTTATGCCTATCAGCACGCAAGAGAGTTGATAAAAAAGCATGTAAACGCAAATGAATCCGATTGTCT
TGTAGCAACAGGAACCGGAATGACGGCTGCTTTAAATAAATTGCAGCGTATTATGGGACTGCGTTCTCAGGACAATATTT
TCAATGTAAAAATCAATTTTGATAATGAAAGGCCGGTAGTTTTTATCACACACATGGAGCATCATTCCAATCAGGTTCCG
TGGTACGAAACCATTGCCGATGTTGTGGTTTTACCCTGCGGAAAAGACAATTTAGTCGATCCGGAGATATTGGCCGAAGA
AATCAAAAAATACGAAAACAGAACGCTTAAAATTGGCTCATTTACCGCTTGTTCAAACGTTACGGGAATTATTACGCCGT
ATCATGAATTAGCCAAAATAATGCATCAAAACGGCGGTTATTGTTTTGTAGATTTTGCAGCGTCGGCGCCGTATGTTTCA
ATTGATATGCATCCGGAAGATCCCGAAGAACAATTGGATGCTATTTTCTTTTCGCCCCATAAATTTCTGGGCGGCCCCGG
AACGTGCGGCATTTTAATTTTCAATGAAAAATTATACCAATCCAGTTTTCCGGATAATCCGGGCGGAGGAAATGTAAAAT
GCACCAATCCGTGGGGCGGATACCATTACAGCGATGCTATTGAAGTAAAAGAAGATGGCGGAACACCGGGATTTCTGCAG
GTTATGCGAACTGCTTTGTGTCTGGAACTGAAAAATAAAATGAACGTTCAAAACATGAAAAACAGAGAAAAAGAACTGCT
TGATCTTTGTTTTCTTGAATTGCAGAAAATAAAAGGTTTAACCATTCTGGGAGATTTAAAAACAGAAAGAATTGGCTGCG
TTTCGTTTACGATCGAGAATATTCATTACAATTTAATCGTACGATTATTGAATGACCGTTTTGGAATTCAGGTTAGGGGC
GGGTGGTCTTGTGCCAGTACATACGCTCATTTTTTATTGAATATTGATGAAGAAAAATCAACCGAAATCACAAACGGAAT
CCTTCAGAAAAATTTAACCGAAAAACCGGGCTGGGTAAGAGTTTCACTTCATCCAACCATGAAAAATGATGAACTTTTAT
TTATTTGTAAAGCCGTTGAACAAATCGTTTTAAATATTCAGGATTGGCAGAAAGCGTATCAATATAATCCTGTAACCAAC
GAATTTGATAATCTTTTGGTAAAAGAAACCATTGAAGACGATGTCAAAAGTTGGTTTTCTTTGGCTTAG

Upstream 100 bases:

>100_bases
TCTTTAACAGAAACCTCAGCGTATAATCCTGATATCGAAGAATATTACAAATGGCTTCAAAGCGGTATTAAAAACTTTAA
AAAGTAAAAATACTTTTAAG

Downstream 100 bases:

>100_bases
ATTTTTGTGTATAAGAAAGGCTGTTCCGCTTTTGGAACAGCCTCTTTTTTAATTTTTTTGGCTGGAGGATTTTTTTATCT
GTATAAACCCCGGCGGAGCG

Product: class V aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 502; Mature: 502

Protein sequence:

>502_residues
MINEMDTILNTKPSELENYFSEFRENTIGVNHSFESIYGPQNILYADWIASGRLYFPIEDIMLRKIGPMIANTHSFSSQT
GKASTYAYQHARELIKKHVNANESDCLVATGTGMTAALNKLQRIMGLRSQDNIFNVKINFDNERPVVFITHMEHHSNQVP
WYETIADVVVLPCGKDNLVDPEILAEEIKKYENRTLKIGSFTACSNVTGIITPYHELAKIMHQNGGYCFVDFAASAPYVS
IDMHPEDPEEQLDAIFFSPHKFLGGPGTCGILIFNEKLYQSSFPDNPGGGNVKCTNPWGGYHYSDAIEVKEDGGTPGFLQ
VMRTALCLELKNKMNVQNMKNREKELLDLCFLELQKIKGLTILGDLKTERIGCVSFTIENIHYNLIVRLLNDRFGIQVRG
GWSCASTYAHFLLNIDEEKSTEITNGILQKNLTEKPGWVRVSLHPTMKNDELLFICKAVEQIVLNIQDWQKAYQYNPVTN
EFDNLLVKETIEDDVKSWFSLA

Sequences:

>Translated_502_residues
MINEMDTILNTKPSELENYFSEFRENTIGVNHSFESIYGPQNILYADWIASGRLYFPIEDIMLRKIGPMIANTHSFSSQT
GKASTYAYQHARELIKKHVNANESDCLVATGTGMTAALNKLQRIMGLRSQDNIFNVKINFDNERPVVFITHMEHHSNQVP
WYETIADVVVLPCGKDNLVDPEILAEEIKKYENRTLKIGSFTACSNVTGIITPYHELAKIMHQNGGYCFVDFAASAPYVS
IDMHPEDPEEQLDAIFFSPHKFLGGPGTCGILIFNEKLYQSSFPDNPGGGNVKCTNPWGGYHYSDAIEVKEDGGTPGFLQ
VMRTALCLELKNKMNVQNMKNREKELLDLCFLELQKIKGLTILGDLKTERIGCVSFTIENIHYNLIVRLLNDRFGIQVRG
GWSCASTYAHFLLNIDEEKSTEITNGILQKNLTEKPGWVRVSLHPTMKNDELLFICKAVEQIVLNIQDWQKAYQYNPVTN
EFDNLLVKETIEDDVKSWFSLA
>Mature_502_residues
MINEMDTILNTKPSELENYFSEFRENTIGVNHSFESIYGPQNILYADWIASGRLYFPIEDIMLRKIGPMIANTHSFSSQT
GKASTYAYQHARELIKKHVNANESDCLVATGTGMTAALNKLQRIMGLRSQDNIFNVKINFDNERPVVFITHMEHHSNQVP
WYETIADVVVLPCGKDNLVDPEILAEEIKKYENRTLKIGSFTACSNVTGIITPYHELAKIMHQNGGYCFVDFAASAPYVS
IDMHPEDPEEQLDAIFFSPHKFLGGPGTCGILIFNEKLYQSSFPDNPGGGNVKCTNPWGGYHYSDAIEVKEDGGTPGFLQ
VMRTALCLELKNKMNVQNMKNREKELLDLCFLELQKIKGLTILGDLKTERIGCVSFTIENIHYNLIVRLLNDRFGIQVRG
GWSCASTYAHFLLNIDEEKSTEITNGILQKNLTEKPGWVRVSLHPTMKNDELLFICKAVEQIVLNIQDWQKAYQYNPVTN
EFDNLLVKETIEDDVKSWFSLA

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787970, Length=339, Percent_Identity=27.1386430678466, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI1789175, Length=340, Percent_Identity=26.7647058823529, Blast_Score=83, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI193211090, Length=502, Percent_Identity=30.0796812749004, Blast_Score=214, Evalue=1e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 56921; Mature: 56921

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINEMDTILNTKPSELENYFSEFRENTIGVNHSFESIYGPQNILYADWIASGRLYFPIED
CCCCHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCEEEEEEHHCCEEEECHHH
IMLRKIGPMIANTHSFSSQTGKASTYAYQHARELIKKHVNANESDCLVATGTGMTAALNK
HHHHHHCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHH
LQRIMGLRSQDNIFNVKINFDNERPVVFITHMEHHSNQVPWYETIADVVVLPCGKDNLVD
HHHHHCCCCCCCEEEEEEEECCCCCEEEEEEECCCCCCCCHHHHHHCEEEEECCCCCCCC
PEILAEEIKKYENRTLKIGSFTACSNVTGIITPYHELAKIMHQNGGYCFVDFAASAPYVS
HHHHHHHHHHHCCCEEEEECEEHHCCCCEEECCHHHHHHHHHCCCCEEEEEECCCCCEEE
IDMHPEDPEEQLDAIFFSPHKFLGGPGTCGILIFNEKLYQSSFPDNPGGGNVKCTNPWGG
EECCCCCHHHHHHEEEECCHHHCCCCCCEEEEEEECHHHHCCCCCCCCCCCEEECCCCCC
YHYSDAIEVKEDGGTPGFLQVMRTALCLELKNKMNVQNMKNREKELLDLCFLELQKIKGL
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCE
TILGDLKTERIGCVSFTIENIHYNLIVRLLNDRFGIQVRGGWSCASTYAHFLLNIDEEKS
EEEECCCCCCEEEEEEEEEHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHEECCCCHH
TEITNGILQKNLTEKPGWVRVSLHPTMKNDELLFICKAVEQIVLNIQDWQKAYQYNPVTN
HHHHHHHHHCCCCCCCCEEEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCC
EFDNLLVKETIEDDVKSWFSLA
HHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MINEMDTILNTKPSELENYFSEFRENTIGVNHSFESIYGPQNILYADWIASGRLYFPIED
CCCCHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCEEEEEEHHCCEEEECHHH
IMLRKIGPMIANTHSFSSQTGKASTYAYQHARELIKKHVNANESDCLVATGTGMTAALNK
HHHHHHCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHH
LQRIMGLRSQDNIFNVKINFDNERPVVFITHMEHHSNQVPWYETIADVVVLPCGKDNLVD
HHHHHCCCCCCCEEEEEEEECCCCCEEEEEEECCCCCCCCHHHHHHCEEEEECCCCCCCC
PEILAEEIKKYENRTLKIGSFTACSNVTGIITPYHELAKIMHQNGGYCFVDFAASAPYVS
HHHHHHHHHHHCCCEEEEECEEHHCCCCEEECCHHHHHHHHHCCCCEEEEEECCCCCEEE
IDMHPEDPEEQLDAIFFSPHKFLGGPGTCGILIFNEKLYQSSFPDNPGGGNVKCTNPWGG
EECCCCCHHHHHHEEEECCHHHCCCCCCEEEEEEECHHHHCCCCCCCCCCCEEECCCCCC
YHYSDAIEVKEDGGTPGFLQVMRTALCLELKNKMNVQNMKNREKELLDLCFLELQKIKGL
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCE
TILGDLKTERIGCVSFTIENIHYNLIVRLLNDRFGIQVRGGWSCASTYAHFLLNIDEEKS
EEEECCCCCCEEEEEEEEEHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHEECCCCHH
TEITNGILQKNLTEKPGWVRVSLHPTMKNDELLFICKAVEQIVLNIQDWQKAYQYNPVTN
HHHHHHHHHCCCCCCCCEEEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCC
EFDNLLVKETIEDDVKSWFSLA
HHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA