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The map label for this gene is dsbD [H]

Identifier: 146299773

GI number: 146299773

Start: 2353866

End: 2355866

Strand: Direct

Name: dsbD [H]

Synonym: Fjoh_2013

Alternate gene names: 146299773

Gene position: 2353866-2355866 (Clockwise)

Preceding gene: 146299772

Following gene: 146299774

Centisome position: 38.61

GC content: 37.53

Gene sequence:

>2001_bases
ATGAAAAATAGCATATTAACTTTCCTTTTACTGCTTTCGGCGAGTATGTTTGGTCAAATGTACAATCCCGTAAAGTGGTC
AGCATCTGTAGAGAAAATTTCAGATAAAGAATATATTTTAAAAGCCAAAGCCGTAATACAATCGGGCTGGCATTTGTACG
GACAATATATTGAAGAAGGAGGACCTTCACCAACCGCTTTTACCTTTAAAAATACGCCAAAAAAATTCGAATTAGTGGGA
AAAACAACCGAAGAAAAAGGTCATGAAACGATCGACAAAATCTTCGATATGAAAATCAAATATTTTGAAGACAAAGCCTT
TTTTACCCAAAAAATCAAACTCATTTCTGACGTTTCATCCATTACAGCCGATGTTGATTTTATGGTTTGCGATGACAGCA
ATTGTTTACCGCCCACAACAGAAGAATTAACTTTTAAAATTCCGGCAGACAAGAAATTGGCTTTCGCCGAAGAAACTCCA
GCTGTAAAAAAAGATTCGGCTGTTGCTGAAGATGTAACATTTGTAAAAGCCGTAGATAAACCAGAAAAAACAGCAGTAAA
TCCCGTTAAGAAAGAAGAATCCAGAGGATTGCTGAGTATTTTCATTATTGCCTTTTTATCAGGATTTGCAGCGCTTTTAA
CGCCTTGCGTTTTCCCAATGATTCCAATGACGGTAAGTTATTTTACCAAGCAGAGTAAAACTAAAGCAGCCGGAATTCGT
AATGCCATGATTTACGGGTTTTCAATCGTAATTATTTACGTTTTATTAGGTTCAATCGTAACCGCAGTTTTTGGTGCCGA
TTCGCTGAATGCACTTTCAACTAACGTTTGGTTCAACCTGATTTTCTTTGTTTTATTGGTTGTTTTTGCGTGTTCCTTTT
TGGGCGCTTTCGAAATTATGCTGCCAAATGCATTAGCCAATAAAGTCGATTCACAAGCCGATAGAGGCGGATTAATCGGG
ATTTTCTTTATGGCTTTGGCTTTAGCCATTGTATCCTTTTCATGTACAGGACCAATCGTAGGAACCTTATTAGTCGAAGC
CGCTTCAAAAGGCGGGATTGCGCCAATTGTTGGAATGTTAGGATTTTCAATCGCCATTGCCCTGCCGTTTTCATTATTTG
CAGCATTTCCGGGCTGGTTAAACGCATTGCCAAAATCAGGAGGATGGCTCAATACCGTAAAAGTAGTTTTAGGCTTTTTA
GAATTGGCTTTAGCCTTCAAATTTTTATCAAATGCCGATTTGGTTCTGCAATTGCATTGGTTAGAAAGAGAAGTTTTTCT
TGCCATTTGGATTGCCGTTTTTGGAGCTTTGGCTTTTTATTTATTCGGAAAAATTACTTTACCTCACGATTCGCCTTTAA
ACCATATTTCGGTAGGAAGATTAAGTTTTGGATTGATCGTTTTAACGTTTACTATTTATTTGATTCCCGGACTTTGGGGC
GCACCTCTTAAATTAATCAGCGGATTTCCTCCGCCAATGTACTACAGCGAATCTCCAGACGGATTAGGCGCTAAAAATAC
TGCCGAAACAACAAAATCTGCTTTGCCGGAAGGCGCAGAATACGGTCCGCAGAATATCATCACTTTTCATGATTACGACA
AAGGAATGGAGTTTGCCAAAAAAGCTGGAAAACCTGTTTTGTTAGATTTTACCGGATATGCCTGCGTAAACTGTCGAAAA
ATGGAAGAATTAGTCTGGTCAGACGCTAAAGTTTTAGGTGTTTTAAATAATGATGTGGTTTTGATTTCGCTTTATGTTGA
CGATAAAAAAGAACTGCCAGAAAGTGAACAATATGTTTCTGAAACAACCGGAAAAAAAATCAAAACCATCGGGAACAAAT
GGAGCGATTTACAGATTAAAACCTATAAAGCAAATGCACAGCCGTTTTATGTAATTGTAGATCACGCTAGTAATTCTTTA
ACAGAAACCTCAGCGTATAATCCTGATATCGAAGAATATTACAAATGGCTTCAAAGCGGTATTAAAAACTTTAAAAAGTA
A

Upstream 100 bases:

>100_bases
ATTTTAGAATCTGAATTAGTAAGCCATTTTCTATGAGAGACCTTTAAGAGAGCTGTTTTTGCCGACAGCTCTTTTTTGTA
AAACAGCAAACCAAAAAACA

Downstream 100 bases:

>100_bases
AAATACTTTTAAGATGATAAATGAAATGGATACTATTTTGAATACAAAACCAAGCGAACTCGAAAACTATTTTTCTGAAT
TTAGAGAAAATACAATTGGA

Product: cytochrome c biogenesis protein, transmembrane region

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 666; Mature: 666

Protein sequence:

>666_residues
MKNSILTFLLLLSASMFGQMYNPVKWSASVEKISDKEYILKAKAVIQSGWHLYGQYIEEGGPSPTAFTFKNTPKKFELVG
KTTEEKGHETIDKIFDMKIKYFEDKAFFTQKIKLISDVSSITADVDFMVCDDSNCLPPTTEELTFKIPADKKLAFAEETP
AVKKDSAVAEDVTFVKAVDKPEKTAVNPVKKEESRGLLSIFIIAFLSGFAALLTPCVFPMIPMTVSYFTKQSKTKAAGIR
NAMIYGFSIVIIYVLLGSIVTAVFGADSLNALSTNVWFNLIFFVLLVVFACSFLGAFEIMLPNALANKVDSQADRGGLIG
IFFMALALAIVSFSCTGPIVGTLLVEAASKGGIAPIVGMLGFSIAIALPFSLFAAFPGWLNALPKSGGWLNTVKVVLGFL
ELALAFKFLSNADLVLQLHWLEREVFLAIWIAVFGALAFYLFGKITLPHDSPLNHISVGRLSFGLIVLTFTIYLIPGLWG
APLKLISGFPPPMYYSESPDGLGAKNTAETTKSALPEGAEYGPQNIITFHDYDKGMEFAKKAGKPVLLDFTGYACVNCRK
MEELVWSDAKVLGVLNNDVVLISLYVDDKKELPESEQYVSETTGKKIKTIGNKWSDLQIKTYKANAQPFYVIVDHASNSL
TETSAYNPDIEEYYKWLQSGIKNFKK

Sequences:

>Translated_666_residues
MKNSILTFLLLLSASMFGQMYNPVKWSASVEKISDKEYILKAKAVIQSGWHLYGQYIEEGGPSPTAFTFKNTPKKFELVG
KTTEEKGHETIDKIFDMKIKYFEDKAFFTQKIKLISDVSSITADVDFMVCDDSNCLPPTTEELTFKIPADKKLAFAEETP
AVKKDSAVAEDVTFVKAVDKPEKTAVNPVKKEESRGLLSIFIIAFLSGFAALLTPCVFPMIPMTVSYFTKQSKTKAAGIR
NAMIYGFSIVIIYVLLGSIVTAVFGADSLNALSTNVWFNLIFFVLLVVFACSFLGAFEIMLPNALANKVDSQADRGGLIG
IFFMALALAIVSFSCTGPIVGTLLVEAASKGGIAPIVGMLGFSIAIALPFSLFAAFPGWLNALPKSGGWLNTVKVVLGFL
ELALAFKFLSNADLVLQLHWLEREVFLAIWIAVFGALAFYLFGKITLPHDSPLNHISVGRLSFGLIVLTFTIYLIPGLWG
APLKLISGFPPPMYYSESPDGLGAKNTAETTKSALPEGAEYGPQNIITFHDYDKGMEFAKKAGKPVLLDFTGYACVNCRK
MEELVWSDAKVLGVLNNDVVLISLYVDDKKELPESEQYVSETTGKKIKTIGNKWSDLQIKTYKANAQPFYVIVDHASNSL
TETSAYNPDIEEYYKWLQSGIKNFKK
>Mature_666_residues
MKNSILTFLLLLSASMFGQMYNPVKWSASVEKISDKEYILKAKAVIQSGWHLYGQYIEEGGPSPTAFTFKNTPKKFELVG
KTTEEKGHETIDKIFDMKIKYFEDKAFFTQKIKLISDVSSITADVDFMVCDDSNCLPPTTEELTFKIPADKKLAFAEETP
AVKKDSAVAEDVTFVKAVDKPEKTAVNPVKKEESRGLLSIFIIAFLSGFAALLTPCVFPMIPMTVSYFTKQSKTKAAGIR
NAMIYGFSIVIIYVLLGSIVTAVFGADSLNALSTNVWFNLIFFVLLVVFACSFLGAFEIMLPNALANKVDSQADRGGLIG
IFFMALALAIVSFSCTGPIVGTLLVEAASKGGIAPIVGMLGFSIAIALPFSLFAAFPGWLNALPKSGGWLNTVKVVLGFL
ELALAFKFLSNADLVLQLHWLEREVFLAIWIAVFGALAFYLFGKITLPHDSPLNHISVGRLSFGLIVLTFTIYLIPGLWG
APLKLISGFPPPMYYSESPDGLGAKNTAETTKSALPEGAEYGPQNIITFHDYDKGMEFAKKAGKPVLLDFTGYACVNCRK
MEELVWSDAKVLGVLNNDVVLISLYVDDKKELPESEQYVSETTGKKIKTIGNKWSDLQIKTYKANAQPFYVIVDHASNSL
TETSAYNPDIEEYYKWLQSGIKNFKK

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=449, Percent_Identity=25.3897550111359, Blast_Score=86, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 73281; Mature: 73281

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNSILTFLLLLSASMFGQMYNPVKWSASVEKISDKEYILKAKAVIQSGWHLYGQYIEEG
CCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHHHHHHHHCHHHHHHHHHCC
GPSPTAFTFKNTPKKFELVGKTTEEKGHETIDKIFDMKIKYFEDKAFFTQKIKLISDVSS
CCCCCEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHH
ITADVDFMVCDDSNCLPPTTEELTFKIPADKKLAFAEETPAVKKDSAVAEDVTFVKAVDK
HHCCCEEEEECCCCCCCCCCCCEEEECCCCCCEEECCCCCCCCCCCHHHHHHHHHHHCCC
PEKTAVNPVKKEESRGLLSIFIIAFLSGFAALLTPCVFPMIPMTVSYFTKQSKTKAAGIR
CCHHCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NAMIYGFSIVIIYVLLGSIVTAVFGADSLNALSTNVWFNLIFFVLLVVFACSFLGAFEIM
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPNALANKVDSQADRGGLIGIFFMALALAIVSFSCTGPIVGTLLVEAASKGGIAPIVGML
CCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHH
GFSIAIALPFSLFAAFPGWLNALPKSGGWLNTVKVVLGFLELALAFKFLSNADLVLQLHW
HHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEH
LEREVFLAIWIAVFGALAFYLFGKITLPHDSPLNHISVGRLSFGLIVLTFTIYLIPGLWG
HHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCC
APLKLISGFPPPMYYSESPDGLGAKNTAETTKSALPEGAEYGPQNIITFHDYDKGMEFAK
CHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHH
KAGKPVLLDFTGYACVNCRKMEELVWSDAKVLGVLNNDVVLISLYVDDKKELPESEQYVS
HCCCEEEEEECCCHHHHHHHHHHHHHCCCCEEEEECCCEEEEEEEECCHHHCCCHHHHHH
ETTGKKIKTIGNKWSDLQIKTYKANAQPFYVIVDHASNSLTETSAYNPDIEEYYKWLQSG
HHCCCHHHHHCCCCCCCEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHH
IKNFKK
HHHHCC
>Mature Secondary Structure
MKNSILTFLLLLSASMFGQMYNPVKWSASVEKISDKEYILKAKAVIQSGWHLYGQYIEEG
CCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHHHHHHHHCHHHHHHHHHCC
GPSPTAFTFKNTPKKFELVGKTTEEKGHETIDKIFDMKIKYFEDKAFFTQKIKLISDVSS
CCCCCEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHH
ITADVDFMVCDDSNCLPPTTEELTFKIPADKKLAFAEETPAVKKDSAVAEDVTFVKAVDK
HHCCCEEEEECCCCCCCCCCCCEEEECCCCCCEEECCCCCCCCCCCHHHHHHHHHHHCCC
PEKTAVNPVKKEESRGLLSIFIIAFLSGFAALLTPCVFPMIPMTVSYFTKQSKTKAAGIR
CCHHCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NAMIYGFSIVIIYVLLGSIVTAVFGADSLNALSTNVWFNLIFFVLLVVFACSFLGAFEIM
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPNALANKVDSQADRGGLIGIFFMALALAIVSFSCTGPIVGTLLVEAASKGGIAPIVGML
CCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHH
GFSIAIALPFSLFAAFPGWLNALPKSGGWLNTVKVVLGFLELALAFKFLSNADLVLQLHW
HHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEH
LEREVFLAIWIAVFGALAFYLFGKITLPHDSPLNHISVGRLSFGLIVLTFTIYLIPGLWG
HHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCC
APLKLISGFPPPMYYSESPDGLGAKNTAETTKSALPEGAEYGPQNIITFHDYDKGMEFAK
CHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHH
KAGKPVLLDFTGYACVNCRKMEELVWSDAKVLGVLNNDVVLISLYVDDKKELPESEQYVS
HCCCEEEEEECCCHHHHHHHHHHHHHCCCCEEEEECCCEEEEEEEECCHHHCCCHHHHHH
ETTGKKIKTIGNKWSDLQIKTYKANAQPFYVIVDHASNSLTETSAYNPDIEEYYKWLQSG
HHCCCHHHHHCCCCCCCEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHH
IKNFKK
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]