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The map label for this gene is mraY

Identifier: 146299567

GI number: 146299567

Start: 2088380

End: 2089612

Strand: Direct

Name: mraY

Synonym: Fjoh_1807

Alternate gene names: 146299567

Gene position: 2088380-2089612 (Clockwise)

Preceding gene: 146299566

Following gene: 146299568

Centisome position: 34.25

GC content: 36.66

Gene sequence:

>1233_bases
ATGCTGTACTATTTATTTGAATATTTTGACAAAACACTAGATGTGCCTGGAACAGGAGTTTTCCAGTACATTACTTTTAG
ATCGGCTTTAGCATTCATGCTTTCATTGCTTTTGTCAACTATTTATGGTAAAAGGGTGATTAACTTTTTGCGTCGTCAGC
AAGTGGGAGAAACTGTACGTGAATTGGGTCTTGCGGGTCAAAACGAAAAAGCAGGTACACCTACAATGGGAGGATTAATT
ATCATTTTTGCCACATTGGTTCCGGTTTTCTTATTTGCCAGACTGCACAACATTTATATCGTGTTGCTTATTGTAACTAC
TTTGTGGATGGGAACTATTGGTTTTGTTGACGATTATATCAAAATATTTAAAAAAGATAAACAAGGATTAAAAGGAATTT
TTAAAGTTATTGGTCAGGTTGGTCTTGGAATTATTGTTGGTGCAGTTTTGTATTTTAATCCTGCTGTTACAGTAAGAACA
GATACAGGAAAAACAGATGTTTTTAAAACCGCAGCAAATACAACAGTTGTACTGCCTGCTCCGGTTGAGGAAAAATCTAC
AGCAACAACAATTCCTTTCGTAAAAAACAACGAATTTGATTATGCAGAAGTTCTTTCTTTTATGGGAGACGGATACGAAA
AATGGGCTTGGTTAGTATTTATTCCGGTAGTGATTTTCATAATCACAGCGGTTTCCAATGGAGCTAATTTGACGGACGGA
ATCGATGGTCTTGCTGCCGGAACCTCCGCAGTTTCTGTCCTCGCGCTCGGGATATTTACATTCGTTTCAGGAAATATCAT
TTTCTCAAATTATCTGAATATTATGTACATCCCTAATTCGGGAGAAATGACCGTCTTTATCTCGGCCTTTGTTGGAGCAT
TGATTGGATTTCTTTGGTACAATTCATTTCCCGCATCCGTATTTATGGGAGATACAGGAAGTTTAACAATTGGAGGAATC
ATTGCCGTATTAGCTATTGCAGTTCGTAAAGAAATATTAATTGTTTTATTCTGCGGAATTTTCCTTGCCGAAAGTGCTTC
AGTAATTATTCAGGTAACCTATTTTAAATATACAAAAAAGCGTTTTGGCGAAGGCCGAAGAATTTTTCTGATGTCACCGC
TGCATCATCATTACCAGAAAAAAGGATACCACGAAAGTAAAATCGTAACCCGTTTCTGGATTGTTGCTGTAATGTTAGCC
ATATTATCAATCGTTACTTTAAAACTAAGATAG

Upstream 100 bases:

>100_bases
TTTAGAACAACTGAATAAATAATAAAAGATTTTAAGTTCAAATACCACCACACAATTGGAATTTGGAATTTCAAAATTGG
AATTTAAAAAATAGAGAAAT

Downstream 100 bases:

>100_bases
ATGAGATTAGTGGTATTAGGTGGAGGAGAAAGCGGGGTTGGAACCGCTATTCTCGGGAAGAAAAAGGGATACGACGTTTT
TGTATCGGATTTTGGAAAGA

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MLYYLFEYFDKTLDVPGTGVFQYITFRSALAFMLSLLLSTIYGKRVINFLRRQQVGETVRELGLAGQNEKAGTPTMGGLI
IIFATLVPVFLFARLHNIYIVLLIVTTLWMGTIGFVDDYIKIFKKDKQGLKGIFKVIGQVGLGIIVGAVLYFNPAVTVRT
DTGKTDVFKTAANTTVVLPAPVEEKSTATTIPFVKNNEFDYAEVLSFMGDGYEKWAWLVFIPVVIFIITAVSNGANLTDG
IDGLAAGTSAVSVLALGIFTFVSGNIIFSNYLNIMYIPNSGEMTVFISAFVGALIGFLWYNSFPASVFMGDTGSLTIGGI
IAVLAIAVRKEILIVLFCGIFLAESASVIIQVTYFKYTKKRFGEGRRIFLMSPLHHHYQKKGYHESKIVTRFWIVAVMLA
ILSIVTLKLR

Sequences:

>Translated_410_residues
MLYYLFEYFDKTLDVPGTGVFQYITFRSALAFMLSLLLSTIYGKRVINFLRRQQVGETVRELGLAGQNEKAGTPTMGGLI
IIFATLVPVFLFARLHNIYIVLLIVTTLWMGTIGFVDDYIKIFKKDKQGLKGIFKVIGQVGLGIIVGAVLYFNPAVTVRT
DTGKTDVFKTAANTTVVLPAPVEEKSTATTIPFVKNNEFDYAEVLSFMGDGYEKWAWLVFIPVVIFIITAVSNGANLTDG
IDGLAAGTSAVSVLALGIFTFVSGNIIFSNYLNIMYIPNSGEMTVFISAFVGALIGFLWYNSFPASVFMGDTGSLTIGGI
IAVLAIAVRKEILIVLFCGIFLAESASVIIQVTYFKYTKKRFGEGRRIFLMSPLHHHYQKKGYHESKIVTRFWIVAVMLA
ILSIVTLKLR
>Mature_410_residues
MLYYLFEYFDKTLDVPGTGVFQYITFRSALAFMLSLLLSTIYGKRVINFLRRQQVGETVRELGLAGQNEKAGTPTMGGLI
IIFATLVPVFLFARLHNIYIVLLIVTTLWMGTIGFVDDYIKIFKKDKQGLKGIFKVIGQVGLGIIVGAVLYFNPAVTVRT
DTGKTDVFKTAANTTVVLPAPVEEKSTATTIPFVKNNEFDYAEVLSFMGDGYEKWAWLVFIPVVIFIITAVSNGANLTDG
IDGLAAGTSAVSVLALGIFTFVSGNIIFSNYLNIMYIPNSGEMTVFISAFVGALIGFLWYNSFPASVFMGDTGSLTIGGI
IAVLAIAVRKEILIVLFCGIFLAESASVIIQVTYFKYTKKRFGEGRRIFLMSPLHHHYQKKGYHESKIVTRFWIVAVMLA
ILSIVTLKLR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=410, Percent_Identity=35.3658536585366, Blast_Score=246, Evalue=3e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_FLAJ1 (A5FIY0)

Other databases:

- EMBL:   CP000685
- RefSeq:   YP_001194158.1
- STRING:   A5FIY0
- GeneID:   5091874
- GenomeReviews:   CP000685_GR
- KEGG:   fjo:Fjoh_1807
- eggNOG:   COG0472
- HOGENOM:   HBG708263
- OMA:   LRQGKGQ
- ProtClustDB:   PRK00108
- BioCyc:   FJOH376686:FJOH_1807-MONOMER
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1

EC number: =2.7.8.13

Molecular weight: Translated: 45314; Mature: 45314

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1e47e228)-; HASH(0x1e444b3c)-; HASH(0x1efc4d7c)-; HASH(0x1dee9f8c)-; HASH(0x1e44480c)-; HASH(0x1e57c468)-; HASH(0x1f30888c)-; HASH(0x1c31d9b8)-; HASH(0x1efc0eb8)-; HASH(0x1efc0c6c)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYYLFEYFDKTLDVPGTGVFQYITFRSALAFMLSLLLSTIYGKRVINFLRRQQVGETVR
CEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELGLAGQNEKAGTPTMGGLIIIFATLVPVFLFARLHNIYIVLLIVTTLWMGTIGFVDDYI
HHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KIFKKDKQGLKGIFKVIGQVGLGIIVGAVLYFNPAVTVRTDTGKTDVFKTAANTTVVLPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHEECCCCEEEEEC
PVEEKSTATTIPFVKNNEFDYAEVLSFMGDGYEKWAWLVFIPVVIFIITAVSNGANLTDG
CCCCCCCCCCCCEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
IDGLAAGTSAVSVLALGIFTFVSGNIIFSNYLNIMYIPNSGEMTVFISAFVGALIGFLWY
CHHHHHHHHHHHHHHHHHHHHHCCCEEEECCEEEEEECCCCCEEEEHHHHHHHHHHHHHH
NSFPASVFMGDTGSLTIGGIIAVLAIAVRKEILIVLFCGIFLAESASVIIQVTYFKYTKK
CCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHH
RFGEGRRIFLMSPLHHHYQKKGYHESKIVTRFWIVAVMLAILSIVTLKLR
HHCCCCEEEEECHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure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HHCCCCEEEEECHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA