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The map label for this gene is asd [H]

Identifier: 146299080

GI number: 146299080

Start: 1511642

End: 1512631

Strand: Direct

Name: asd [H]

Synonym: Fjoh_1320

Alternate gene names: 146299080

Gene position: 1511642-1512631 (Clockwise)

Preceding gene: 146299079

Following gene: 146299081

Centisome position: 24.79

GC content: 36.57

Gene sequence:

>990_bases
ATGAGAATTGCAGTTGTAGGTGCTACCGGAATGGTTGGCGAAGTAATGCTTAAAGTTTTAGCAGAAAGAAATTTTCCTGT
TACGGAATTAATTCCTGTTGCATCAGAAAGATCAGTTGGAAAAGAAATCGAATACAAAGGAACCAAATATAAAGTAGTAG
GATTACAAACAGCTGTTGATATGAAAGCTGATATCGCTGTTTTTTCTGCAGGAGGAGATACATCTTTAGAATGGGCTCCA
AAATTTGCTGCTGCCGGAACAACTGTTATCGACAACTCATCTGCATGGAGAATGGATCCGACTAAAAAATTAGTGGTTCC
GGAAATTAATGCCTCTGTATTAACAAAAGAAGATAAAATTATTGCAAACCCAAACTGTTCTACTATTCAAATGGTATTGG
CTTTGGCTCCTTTGCATAGAAAATACAACATTAAAAGAATCATTGTTTCTACTTACCAATCAATTACTGGAACTGGTGTA
AAAGCAGTTAAACAATTAGAAAACGAATACGCAGGAATTCAGGGTGATATGGCTTACAAATATCCAATTCACCGAAATGC
AATTCCACACTGCGATAGTTTTGAGGATAACGGATACACTAAAGAAGAAATGAAATTAGTTCGCGAAACTCAAAAAATTC
TTGGTGACAATACCATTAGAGTTACTGCTACTGCAGTTCGTGTACCAGTAGTAGGCGGACACAGCGAAGCTGTAAACGTT
GAGTTTACAAATGATTTTGATGTAAGTGAAGTTCGTGAAATTTTACACAATACGGATGGAGTAGTAGTACAGGATAATTT
AGATACCTTTACATACCCAATGCCATTATATGCAGAAGGTAAAAATGATGTTTTTGTTGGAAGAATCCGTCGTGATGAAA
GCCAGCCAAACACATTAAACATGTGGATCGTTGCTGATAACTTAAGAAAAGGCGCTGCAACAAACACGATTCAAATCGCT
GAATATTTAATTCAGGCTGGTTTGGTATAA

Upstream 100 bases:

>100_bases
ACAACATTTTGTTATTTTTTGTGAATCACCTTGCCAAGACTTTTATTATACTTATTTTTGCGATATAAATTAGATTAATT
GATTATTTAAAAATATAAAA

Downstream 100 bases:

>100_bases
TTGAGAGATTAAATAAAATTGTTATAAAGAGAAAACCGTAATTGCAGTAATGTAATTACGGTTTTTTTGTGTTTTATAAA
TAGCTTATTTTGATAGTTTT

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MRIAVVGATGMVGEVMLKVLAERNFPVTELIPVASERSVGKEIEYKGTKYKVVGLQTAVDMKADIAVFSAGGDTSLEWAP
KFAAAGTTVIDNSSAWRMDPTKKLVVPEINASVLTKEDKIIANPNCSTIQMVLALAPLHRKYNIKRIIVSTYQSITGTGV
KAVKQLENEYAGIQGDMAYKYPIHRNAIPHCDSFEDNGYTKEEMKLVRETQKILGDNTIRVTATAVRVPVVGGHSEAVNV
EFTNDFDVSEVREILHNTDGVVVQDNLDTFTYPMPLYAEGKNDVFVGRIRRDESQPNTLNMWIVADNLRKGAATNTIQIA
EYLIQAGLV

Sequences:

>Translated_329_residues
MRIAVVGATGMVGEVMLKVLAERNFPVTELIPVASERSVGKEIEYKGTKYKVVGLQTAVDMKADIAVFSAGGDTSLEWAP
KFAAAGTTVIDNSSAWRMDPTKKLVVPEINASVLTKEDKIIANPNCSTIQMVLALAPLHRKYNIKRIIVSTYQSITGTGV
KAVKQLENEYAGIQGDMAYKYPIHRNAIPHCDSFEDNGYTKEEMKLVRETQKILGDNTIRVTATAVRVPVVGGHSEAVNV
EFTNDFDVSEVREILHNTDGVVVQDNLDTFTYPMPLYAEGKNDVFVGRIRRDESQPNTLNMWIVADNLRKGAATNTIQIA
EYLIQAGLV
>Mature_329_residues
MRIAVVGATGMVGEVMLKVLAERNFPVTELIPVASERSVGKEIEYKGTKYKVVGLQTAVDMKADIAVFSAGGDTSLEWAP
KFAAAGTTVIDNSSAWRMDPTKKLVVPEINASVLTKEDKIIANPNCSTIQMVLALAPLHRKYNIKRIIVSTYQSITGTGV
KAVKQLENEYAGIQGDMAYKYPIHRNAIPHCDSFEDNGYTKEEMKLVRETQKILGDNTIRVTATAVRVPVVGGHSEAVNV
EFTNDFDVSEVREILHNTDGVVVQDNLDTFTYPMPLYAEGKNDVFVGRIRRDESQPNTLNMWIVADNLRKGAATNTIQIA
EYLIQAGLV

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=336, Percent_Identity=34.5238095238095, Blast_Score=171, Evalue=6e-44,
Organism=Escherichia coli, GI1789841, Length=356, Percent_Identity=26.4044943820225, Blast_Score=100, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6320362, Length=377, Percent_Identity=26.2599469496021, Blast_Score=73, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 36193; Mature: 36193

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIAVVGATGMVGEVMLKVLAERNFPVTELIPVASERSVGKEIEYKGTKYKVVGLQTAVD
CEEEEEECCCHHHHHHHHHHHHCCCCHHHEECCCCCCCCCCEEEECCCEEEEEEEEEEEC
MKADIAVFSAGGDTSLEWAPKFAAAGTTVIDNSSAWRMDPTKKLVVPEINASVLTKEDKI
CEEEEEEEECCCCCCCEECCCHHCCCCEEEECCCCEEECCCCEEEEECCCCEEEECCCCE
IANPNCSTIQMVLALAPLHRKYNIKRIIVSTYQSITGTGVKAVKQLENEYAGIQGDMAYK
EECCCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEE
YPIHRNAIPHCDSFEDNGYTKEEMKLVRETQKILGDNTIRVTATAVRVPVVGGHSEAVNV
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEEEEEEECCCCCEEEE
EFTNDFDVSEVREILHNTDGVVVQDNLDTFTYPMPLYAEGKNDVFVGRIRRDESQPNTLN
EECCCCCHHHHHHHHHCCCCEEEECCCCCEECCCEEEECCCCCEEEEEEECCCCCCCEEE
MWIVADNLRKGAATNTIQIAEYLIQAGLV
EEEEECCCCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MRIAVVGATGMVGEVMLKVLAERNFPVTELIPVASERSVGKEIEYKGTKYKVVGLQTAVD
CEEEEEECCCHHHHHHHHHHHHCCCCHHHEECCCCCCCCCCEEEECCCEEEEEEEEEEEC
MKADIAVFSAGGDTSLEWAPKFAAAGTTVIDNSSAWRMDPTKKLVVPEINASVLTKEDKI
CEEEEEEEECCCCCCCEECCCHHCCCCEEEECCCCEEECCCCEEEEECCCCEEEECCCCE
IANPNCSTIQMVLALAPLHRKYNIKRIIVSTYQSITGTGVKAVKQLENEYAGIQGDMAYK
EECCCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEE
YPIHRNAIPHCDSFEDNGYTKEEMKLVRETQKILGDNTIRVTATAVRVPVVGGHSEAVNV
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEEEEEEECCCCCEEEE
EFTNDFDVSEVREILHNTDGVVVQDNLDTFTYPMPLYAEGKNDVFVGRIRRDESQPNTLN
EECCCCCHHHHHHHHHCCCCEEEECCCCCEECCCEEEECCCCCEEEEEEECCCCCCCEEE
MWIVADNLRKGAATNTIQIAEYLIQAGLV
EEEEECCCCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]