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The map label for this gene is atpA

Identifier: 146298820

GI number: 146298820

Start: 1201575

End: 1203152

Strand: Direct

Name: atpA

Synonym: Fjoh_1059

Alternate gene names: 146298820

Gene position: 1201575-1203152 (Clockwise)

Preceding gene: 146298819

Following gene: 146298821

Centisome position: 19.71

GC content: 37.71

Gene sequence:

>1578_bases
ATGGCGGAAATCAAACCTGCTGAAATTTCAGCAATATTAAGAAAGCAAGTAGAAGGTTTTGAATCTGGTGCTACGCTAGA
GGAAGTAGGAACAGTACTTCAAGTTGGAGATGGTATTGCTCGTGTTTACGGGCTATCTAATGTTCAATATGGTGAGTTAG
TAGAATTCGATAACGGTATGGAAGGTATCGTATTGAATCTTGAAGAGGATAATGTTGGGGTTGTACTTTTAGGACCATCA
ACAGGAATTAAAGAAGGATCTACTGCAAAAAGAACTCAGCGTATTGCTTCTCTTAAAGTAGGTGAGCAAATGGTAGGACG
TGTAGTTAACACTCTTGGTTTTCCAATTGATGGAAAAGGTCCAATTGGCGGAGACTTATACGAAATGCCATTAGAAAGAA
AAGCACCTGGTGTTATCTTCCGTCAGCCGGTAACTGAGCCATTACAAACTGGAGTAAAAGCAGTTGATGCTATGATCCCG
GTAGGTCGTGGACAACGTGAGCTTGTAATTGGTGACCGTCAAACAGGTAAATCAACTGTTTGTATCGATACAATCTTAAA
TCAAAAAGAATTTTACGATGCAGGAAAACCTGTATTCTGTATATATGTTGCAATTGGACAAAAAGCTTCAACTGTAGCAG
GAATCGCTAAAATGTTAGAAGAAAAAGGAGCAATGGCTTATACAGTTATCGTTGCTGCTAATGCTTCTGATCCAGCTCCA
ATGCAAGTTTATGCTCCATTCGCTGGTGCTGCAATTGGAGAATACTTTAGAGATTCAGGTCGTCCAGCACTTATCGTGTA
TGATGATTTATCTAAACAAGCTGTTGCTTACCGTGAGGTTTCTCTTTTATTAAGAAGACCACCGGGACGTGAGGCTTACC
CTGGAGACGTTTTCTACTTACACTCTCGTTTATTAGAGCGTGCTTGTAAAGTAATTGCTGATGATGGTATCGCTAAAAAC
ATGAACGATTTACCAGAGTCTATTAAGCCTATCGTAAAAGGTGGTGGTTCTTTAACTGCTTTACCAATTATCGAAACTCA
GGCTGGTGACGTTTCTGCATATATCCCAACAAACGTAATTTCGATTACAGATGGTCAGATTTTCCTTGATGGAGATTTGT
TCAACTCAGGGGTTCGTCCTGCAATTAACGTAGGTATCTCTGTATCTCGTGTTGGAGGTAATGCTCAAATTAAATCAATG
AAAAAAGTTTCTGGAACTTTAAAATTAGACCAGGCTCAATTCCGTGAATTAGAAGCTTTCGCTAAATTTGGTTCTGACTT
AGATTCTGTTACTTTAAACGTAATTGAAAAAGGAAAAAGAAACGTTGAGATCTTGAAACAAGGTTTAAATGATCCTTATA
CAGTTGAAAACCAAGTAGCTATTATTTATGCTGGTTCTAAAAACTTATTAAGAAACGTTCCTGTAGAAAAAGTAAAAGAA
TTTGAAGCTGATTTCTTAGCATACTTAAACAGTAAACATAAAGATACGCTTAACGCGTTGAAAGCTGGTAAATTAGATGA
CAGCATTACAGATGTTATCGAAAAAGCAGCAAAAGAAATCTCAGCAAAATATAACTAA

Upstream 100 bases:

>100_bases
AATCAATACAATGCTTCTGTTGCAAACAGATTACAAGTATTAAAAAGAGAGTTAAGTAATTAGTTTTATAACACAAAAAG
TGTCTAAATTATAAATTAAG

Downstream 100 bases:

>100_bases
TTTTAGTTGACGGTTGTTGGTTGATTGTTTTTGGAATTTTCCATTACTATCAACCAACAACTAACAACCAACAACGATAG
TACATGGCAAATTTAAAGGA

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha

Number of amino acids: Translated: 525; Mature: 524

Protein sequence:

>525_residues
MAEIKPAEISAILRKQVEGFESGATLEEVGTVLQVGDGIARVYGLSNVQYGELVEFDNGMEGIVLNLEEDNVGVVLLGPS
TGIKEGSTAKRTQRIASLKVGEQMVGRVVNTLGFPIDGKGPIGGDLYEMPLERKAPGVIFRQPVTEPLQTGVKAVDAMIP
VGRGQRELVIGDRQTGKSTVCIDTILNQKEFYDAGKPVFCIYVAIGQKASTVAGIAKMLEEKGAMAYTVIVAANASDPAP
MQVYAPFAGAAIGEYFRDSGRPALIVYDDLSKQAVAYREVSLLLRRPPGREAYPGDVFYLHSRLLERACKVIADDGIAKN
MNDLPESIKPIVKGGGSLTALPIIETQAGDVSAYIPTNVISITDGQIFLDGDLFNSGVRPAINVGISVSRVGGNAQIKSM
KKVSGTLKLDQAQFRELEAFAKFGSDLDSVTLNVIEKGKRNVEILKQGLNDPYTVENQVAIIYAGSKNLLRNVPVEKVKE
FEADFLAYLNSKHKDTLNALKAGKLDDSITDVIEKAAKEISAKYN

Sequences:

>Translated_525_residues
MAEIKPAEISAILRKQVEGFESGATLEEVGTVLQVGDGIARVYGLSNVQYGELVEFDNGMEGIVLNLEEDNVGVVLLGPS
TGIKEGSTAKRTQRIASLKVGEQMVGRVVNTLGFPIDGKGPIGGDLYEMPLERKAPGVIFRQPVTEPLQTGVKAVDAMIP
VGRGQRELVIGDRQTGKSTVCIDTILNQKEFYDAGKPVFCIYVAIGQKASTVAGIAKMLEEKGAMAYTVIVAANASDPAP
MQVYAPFAGAAIGEYFRDSGRPALIVYDDLSKQAVAYREVSLLLRRPPGREAYPGDVFYLHSRLLERACKVIADDGIAKN
MNDLPESIKPIVKGGGSLTALPIIETQAGDVSAYIPTNVISITDGQIFLDGDLFNSGVRPAINVGISVSRVGGNAQIKSM
KKVSGTLKLDQAQFRELEAFAKFGSDLDSVTLNVIEKGKRNVEILKQGLNDPYTVENQVAIIYAGSKNLLRNVPVEKVKE
FEADFLAYLNSKHKDTLNALKAGKLDDSITDVIEKAAKEISAKYN
>Mature_524_residues
AEIKPAEISAILRKQVEGFESGATLEEVGTVLQVGDGIARVYGLSNVQYGELVEFDNGMEGIVLNLEEDNVGVVLLGPST
GIKEGSTAKRTQRIASLKVGEQMVGRVVNTLGFPIDGKGPIGGDLYEMPLERKAPGVIFRQPVTEPLQTGVKAVDAMIPV
GRGQRELVIGDRQTGKSTVCIDTILNQKEFYDAGKPVFCIYVAIGQKASTVAGIAKMLEEKGAMAYTVIVAANASDPAPM
QVYAPFAGAAIGEYFRDSGRPALIVYDDLSKQAVAYREVSLLLRRPPGREAYPGDVFYLHSRLLERACKVIADDGIAKNM
NDLPESIKPIVKGGGSLTALPIIETQAGDVSAYIPTNVISITDGQIFLDGDLFNSGVRPAINVGISVSRVGGNAQIKSMK
KVSGTLKLDQAQFRELEAFAKFGSDLDSVTLNVIEKGKRNVEILKQGLNDPYTVENQVAIIYAGSKNLLRNVPVEKVKEF
EADFLAYLNSKHKDTLNALKAGKLDDSITDVIEKAAKEISAKYN

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI50345984, Length=521, Percent_Identity=57.0057581573896, Blast_Score=583, Evalue=1e-166,
Organism=Homo sapiens, GI4757810, Length=521, Percent_Identity=57.0057581573896, Blast_Score=583, Evalue=1e-166,
Organism=Homo sapiens, GI19913426, Length=464, Percent_Identity=26.7241379310345, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI19913428, Length=469, Percent_Identity=26.226012793177, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI32189394, Length=362, Percent_Identity=23.2044198895028, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI1790172, Length=509, Percent_Identity=52.6522593320236, Blast_Score=520, Evalue=1e-149,
Organism=Escherichia coli, GI1790170, Length=376, Percent_Identity=23.936170212766, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1788251, Length=395, Percent_Identity=28.3544303797468, Blast_Score=89, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI71988063, Length=504, Percent_Identity=58.9285714285714, Blast_Score=581, Evalue=1e-166,
Organism=Caenorhabditis elegans, GI71988080, Length=504, Percent_Identity=58.9285714285714, Blast_Score=581, Evalue=1e-166,
Organism=Caenorhabditis elegans, GI71988074, Length=504, Percent_Identity=56.1507936507937, Blast_Score=542, Evalue=1e-154,
Organism=Caenorhabditis elegans, GI17570191, Length=461, Percent_Identity=25.5965292841649, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17510931, Length=463, Percent_Identity=24.622030237581, Blast_Score=96, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI71988068, Length=78, Percent_Identity=55.1282051282051, Blast_Score=92, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI25144756, Length=333, Percent_Identity=22.8228228228228, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=58, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319370, Length=524, Percent_Identity=54.3893129770992, Blast_Score=565, Evalue=1e-162,
Organism=Saccharomyces cerevisiae, GI6319603, Length=410, Percent_Identity=28.0487804878049, Blast_Score=107, Evalue=6e-24,
Organism=Saccharomyces cerevisiae, GI6322581, Length=354, Percent_Identity=25.7062146892655, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24658560, Length=524, Percent_Identity=56.2977099236641, Blast_Score=574, Evalue=1e-164,
Organism=Drosophila melanogaster, GI281361666, Length=468, Percent_Identity=26.2820512820513, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24646341, Length=468, Percent_Identity=26.2820512820513, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI17136796, Length=468, Percent_Identity=26.2820512820513, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24638766, Length=349, Percent_Identity=23.7822349570201, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI28574560, Length=449, Percent_Identity=24.7216035634744, Blast_Score=82, Evalue=1e-15,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPA_FLAJ1 (A5FL34)

Other databases:

- EMBL:   CP000685
- RefSeq:   YP_001193411.1
- ProteinModelPortal:   A5FL34
- STRING:   A5FL34
- GeneID:   5091789
- GenomeReviews:   CP000685_GR
- KEGG:   fjo:Fjoh_1059
- eggNOG:   COG0056
- HOGENOM:   HBG565875
- OMA:   EMALTLW
- ProtClustDB:   PRK09281
- BioCyc:   FJOH376686:FJOH_1059-MONOMER
- HAMAP:   MF_01346
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF3
- TIGRFAMs:   TIGR00962

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 56457; Mature: 56325

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEIKPAEISAILRKQVEGFESGATLEEVGTVLQVGDGIARVYGLSNVQYGELVEFDNGM
CCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHCCCCCCCCCEEECCCCC
EGIVLNLEEDNVGVVLLGPSTGIKEGSTAKRTQRIASLKVGEQMVGRVVNTLGFPIDGKG
CEEEEEEECCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PIGGDLYEMPLERKAPGVIFRQPVTEPLQTGVKAVDAMIPVGRGQRELVIGDRQTGKSTV
CCCCCHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEE
CIDTILNQKEFYDAGKPVFCIYVAIGQKASTVAGIAKMLEEKGAMAYTVIVAANASDPAP
EHHHHHCHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCC
MQVYAPFAGAAIGEYFRDSGRPALIVYDDLSKQAVAYREVSLLLRRPPGREAYPGDVFYL
EEEECCHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHH
HSRLLERACKVIADDGIAKNMNDLPESIKPIVKGGGSLTALPIIETQAGDVSAYIPTNVI
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCCEEEECCCCEE
SITDGQIFLDGDLFNSGVRPAINVGISVSRVGGNAQIKSMKKVSGTLKLDQAQFRELEAF
EEECCEEEEECCHHCCCCCCEEECCEEEEECCCCHHHHHHHHHHCCEEECHHHHHHHHHH
AKFGSDLDSVTLNVIEKGKRNVEILKQGLNDPYTVENQVAIIYAGSKNLLRNVPVEKVKE
HHHCCCHHHHHHHHHHCCCCCHHHHHHCCCCCCEECCCEEEEEECCHHHHHCCCHHHHHH
FEADFLAYLNSKHKDTLNALKAGKLDDSITDVIEKAAKEISAKYN
HHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AEIKPAEISAILRKQVEGFESGATLEEVGTVLQVGDGIARVYGLSNVQYGELVEFDNGM
CCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHCCCCCCCCCEEECCCCC
EGIVLNLEEDNVGVVLLGPSTGIKEGSTAKRTQRIASLKVGEQMVGRVVNTLGFPIDGKG
CEEEEEEECCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PIGGDLYEMPLERKAPGVIFRQPVTEPLQTGVKAVDAMIPVGRGQRELVIGDRQTGKSTV
CCCCCHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEE
CIDTILNQKEFYDAGKPVFCIYVAIGQKASTVAGIAKMLEEKGAMAYTVIVAANASDPAP
EHHHHHCHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCC
MQVYAPFAGAAIGEYFRDSGRPALIVYDDLSKQAVAYREVSLLLRRPPGREAYPGDVFYL
EEEECCHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHH
HSRLLERACKVIADDGIAKNMNDLPESIKPIVKGGGSLTALPIIETQAGDVSAYIPTNVI
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCCEEEECCCCEE
SITDGQIFLDGDLFNSGVRPAINVGISVSRVGGNAQIKSMKKVSGTLKLDQAQFRELEAF
EEECCEEEEECCHHCCCCCCEEECCEEEEECCCCHHHHHHHHHHCCEEECHHHHHHHHHH
AKFGSDLDSVTLNVIEKGKRNVEILKQGLNDPYTVENQVAIIYAGSKNLLRNVPVEKVKE
HHHCCCHHHHHHHHHHCCCCCHHHHHHCCCCCCEECCCEEEEEECCHHHHHCCCHHHHHH
FEADFLAYLNSKHKDTLNALKAGKLDDSITDVIEKAAKEISAKYN
HHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA