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The map label for this gene is yeeZ [H]

Identifier: 146298637

GI number: 146298637

Start: 987771

End: 988583

Strand: Direct

Name: yeeZ [H]

Synonym: Fjoh_0875

Alternate gene names: 146298637

Gene position: 987771-988583 (Clockwise)

Preceding gene: 146298636

Following gene: 146298638

Centisome position: 16.2

GC content: 32.6

Gene sequence:

>813_bases
ATGAAACAAATAAGTATATTGGGTTGCGGCTGGCTGGGTTTGCCTTTAGCAAAAAAACTAATCGAAAAAGGACATACGGT
AAACGGATCAACAACTTCTGAAAATAAACTTTCAATATTAAAAGATGCTGGAATATATCCATTTTTGGTTACCGTTGAAA
GCGACAGCGTTTCTAAAAACTTTACTGATTTTCTAGCCGGAAGCGAAATCCTGATTATTGATATTCCACCCAAGTTACGC
GCGGTTGCTTCAGATTCTAATATGGTTTTTGTACAAAAAATCGAAAACCTAATCCCATTTATAGAAAAATCAACCATTCA
GAAAATACTTTTTGTGAGTTCAACTTCTGTTTATGGAGATGATAATGATAGTATTACCGAAGAAACAATTCCTAATCCGG
AAACCGAAAGCGGAAAACAATTGCTTTTAGCAGAAAAAATTCTTCAAAATAATCCAAACTTCGAAACTACGATTTTGCGT
TTCGGCGGATTAATTGGTAAAGATCGTCATCCTGTTAAGTTTTTAGCGGGAAAAGAAAATCTCGAAAATCCAGATGCACC
AGTAAATCTAATTCATCAAAATGACTGCATTGGAGTTATTGAAGCAATCATAAACCAAGAAAAATGGAACACTGTTTTTA
ATGCCGTTGCTCCTTTTCATCCAACAAGAGAGGAATATTATACTCTAAAAGCAAAAGAACAAAACTTGATTTTACCACAA
TTCAGTTCAGAGAAATCAAATATTAAAAAGACTATTTCAGGCAAAAAAATTGAAAATATTCTAAACTATCAATTTCAGTT
GAAAAATTATTAA

Upstream 100 bases:

>100_bases
ATTAAAATGATTTTCAAATCTGTTTAAATCTGTAAAATCTGCGTGAAGCAAAAACCTCTGAACCTTTGTATCTTTGTTTC
TTTGAATCTCAAAAAAGAAA

Downstream 100 bases:

>100_bases
ACGATATAAGTTGTGTAAGTTCATTTAATCGAGACTTCCCAAACTTTGCATAGCAAAACAATTACTGATCTAACTTATAT
GGTTTAAAAAACTTTGCGAA

Product: NAD-dependent epimerase/dehydratase

Products: dTDP-4-dehydro-6-deoxy-D-glucose; H2O

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MKQISILGCGWLGLPLAKKLIEKGHTVNGSTTSENKLSILKDAGIYPFLVTVESDSVSKNFTDFLAGSEILIIDIPPKLR
AVASDSNMVFVQKIENLIPFIEKSTIQKILFVSSTSVYGDDNDSITEETIPNPETESGKQLLLAEKILQNNPNFETTILR
FGGLIGKDRHPVKFLAGKENLENPDAPVNLIHQNDCIGVIEAIINQEKWNTVFNAVAPFHPTREEYYTLKAKEQNLILPQ
FSSEKSNIKKTISGKKIENILNYQFQLKNY

Sequences:

>Translated_270_residues
MKQISILGCGWLGLPLAKKLIEKGHTVNGSTTSENKLSILKDAGIYPFLVTVESDSVSKNFTDFLAGSEILIIDIPPKLR
AVASDSNMVFVQKIENLIPFIEKSTIQKILFVSSTSVYGDDNDSITEETIPNPETESGKQLLLAEKILQNNPNFETTILR
FGGLIGKDRHPVKFLAGKENLENPDAPVNLIHQNDCIGVIEAIINQEKWNTVFNAVAPFHPTREEYYTLKAKEQNLILPQ
FSSEKSNIKKTISGKKIENILNYQFQLKNY
>Mature_270_residues
MKQISILGCGWLGLPLAKKLIEKGHTVNGSTTSENKLSILKDAGIYPFLVTVESDSVSKNFTDFLAGSEILIIDIPPKLR
AVASDSNMVFVQKIENLIPFIEKSTIQKILFVSSTSVYGDDNDSITEETIPNPETESGKQLLLAEKILQNNPNFETTILR
FGGLIGKDRHPVKFLAGKENLENPDAPVNLIHQNDCIGVIEAIINQEKWNTVFNAVAPFHPTREEYYTLKAKEQNLILPQ
FSSEKSNIKKTISGKKIENILNYQFQLKNY

Specific function: Unknown

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788327, Length=267, Percent_Identity=34.8314606741573, Blast_Score=160, Evalue=1e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: 4.2.1.46

Molecular weight: Translated: 30179; Mature: 30179

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQISILGCGWLGLPLAKKLIEKGHTVNGSTTSENKLSILKDAGIYPFLVTVESDSVSKN
CCEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEHCCCCCCEEEEEEECCCCCCH
FTDFLAGSEILIIDIPPKLRAVASDSNMVFVQKIENLIPFIEKSTIQKILFVSSTSVYGD
HHHHHCCCCEEEEECCCHHEEEECCCCEEHHHHHHHHHHHHHHHHHHHEEEEECCEECCC
DNDSITEETIPNPETESGKQLLLAEKILQNNPNFETTILRFGGLIGKDRHPVKFLAGKEN
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEHHEECCCCCCCCCCCEEEEECCCC
LENPDAPVNLIHQNDCIGVIEAIINQEKWNTVFNAVAPFHPTREEYYTLKAKEQNLILPQ
CCCCCCCEEEEECCCHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHEEEEEECCCCEECCC
FSSEKSNIKKTISGKKIENILNYQFQLKNY
CCCCHHHHHHHHCHHHHHHHHCEEEEECCC
>Mature Secondary Structure
MKQISILGCGWLGLPLAKKLIEKGHTVNGSTTSENKLSILKDAGIYPFLVTVESDSVSKN
CCEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEHCCCCCCEEEEEEECCCCCCH
FTDFLAGSEILIIDIPPKLRAVASDSNMVFVQKIENLIPFIEKSTIQKILFVSSTSVYGD
HHHHHCCCCEEEEECCCHHEEEECCCCEEHHHHHHHHHHHHHHHHHHHEEEEECCEECCC
DNDSITEETIPNPETESGKQLLLAEKILQNNPNFETTILRFGGLIGKDRHPVKFLAGKEN
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEHHEECCCCCCCCCCCEEEEECCCC
LENPDAPVNLIHQNDCIGVIEAIINQEKWNTVFNAVAPFHPTREEYYTLKAKEQNLILPQ
CCCCCCCEEEEECCCHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHEEEEEECCCCEECCC
FSSEKSNIKKTISGKKIENILNYQFQLKNY
CCCCHHHHHHHHCHHHHHHHHCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dTDPglucose

Specific reaction: dTDP-glucose = dTDP-4-dehydro-6-deoxy-D-glucose + H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]