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The map label for this gene is thiL [H]

Identifier: 146298553

GI number: 146298553

Start: 881497

End: 882543

Strand: Direct

Name: thiL [H]

Synonym: Fjoh_0791

Alternate gene names: 146298553

Gene position: 881497-882543 (Clockwise)

Preceding gene: 146298550

Following gene: 146298559

Centisome position: 14.46

GC content: 36.29

Gene sequence:

>1047_bases
ATGATCGAAGATAAAAATCCGCAACGCACCAGCATATCACAATTAGGCGAGTTTGGCTTAATTGAGCATTTAACACGAAA
CTTTGATGTTACACAAGAATCTACTTTAAAAAGTATTGGCGACGATGCAGCTGTTCTTGATTTTAAAGACAAAAAAACCG
TTATTTCAACCGATTTATTAATTGAAGGTGTTCACTTTGATCTGGCTTATATGCCTTTGAAACATTTAGGTTATAAAGCA
GTTATAGTAAACCTGTCTGATATTTGCGCCATGAATGCAAAACCAACTCAAATTACAGTTTCAGTTGCTGTTTCTAATCG
CTTTCCTTTGGAAGCTTTAGAAGAATTATTTGAAGGTATTACACATGCAGCAAAAGAATACAAAGTAGATGTTATTGGCG
GCGATACTACCTCATCTCAAAAAGGATTAATTATAAGTATTACAGCAATTGGTGAAGCTGATGAAAATGAAATTGCTTAC
CGAAACGGTGCCAAACAAACCGATTTACTGGTTGTAACGGGAGATATTGGCGCAGCTTATATGGGATTACAGGTTTTAGA
GCGTGAAAAACAGGTTTTTCAGGTAAATCCAAACAGTCAGCCGGATTTAGATCCTTATACGTATTTGGTCGAAAGACAAT
TAAAACCAGAAGCCAGAACAGATGTTCGTACACTTTTGCATGCCCTTGAAATTAAACCAACTTCAATGATTGATATTTCT
GATGGTTTATCTTCAGAGATTATACATTTGTGCAAACAGTCAAAAGTGGGCTGTAATTTATATGAAGATAAACTTCCGTT
AGATCCTCAGTTTATTTCGACTTGCGAAGAGTTTAATATCGACAGCACAACCGTTGCCATTAACGGCGGAGAGGACTATG
AACTCCTTTTTACGATTGATATTAATGATTTTGATAAGATAAAAGGAAATCCAAACTTTTCTATCATTGGCCACATGGCA
GATGAAAGCGAAGGAATTCATTTGGTAACCCGTGCTAATACTAAGATTGCTTTAAAAGCACGCGGCTGGGATGCTTTGAG
TGAATAA

Upstream 100 bases:

>100_bases
TTAGAACCTTAGCTTCTTAGTCCCGATAGCTATCGGGATTAGTATCTTTAAAAAAAACCTTTGTACCTTTGCTCCTTACA
AACTTTGGAACTCAGAAAAA

Downstream 100 bases:

>100_bases
ATTCAGTCTCAGTATTCAGTCTCAGTTTATAAAACCTGATAGAATTAGATTCTGTCAGGTTTTATTTTTATGTATTTAAA
TCTAAGATCTACATTCGTAA

Product: thiamine-monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MIEDKNPQRTSISQLGEFGLIEHLTRNFDVTQESTLKSIGDDAAVLDFKDKKTVISTDLLIEGVHFDLAYMPLKHLGYKA
VIVNLSDICAMNAKPTQITVSVAVSNRFPLEALEELFEGITHAAKEYKVDVIGGDTTSSQKGLIISITAIGEADENEIAY
RNGAKQTDLLVVTGDIGAAYMGLQVLEREKQVFQVNPNSQPDLDPYTYLVERQLKPEARTDVRTLLHALEIKPTSMIDIS
DGLSSEIIHLCKQSKVGCNLYEDKLPLDPQFISTCEEFNIDSTTVAINGGEDYELLFTIDINDFDKIKGNPNFSIIGHMA
DESEGIHLVTRANTKIALKARGWDALSE

Sequences:

>Translated_348_residues
MIEDKNPQRTSISQLGEFGLIEHLTRNFDVTQESTLKSIGDDAAVLDFKDKKTVISTDLLIEGVHFDLAYMPLKHLGYKA
VIVNLSDICAMNAKPTQITVSVAVSNRFPLEALEELFEGITHAAKEYKVDVIGGDTTSSQKGLIISITAIGEADENEIAY
RNGAKQTDLLVVTGDIGAAYMGLQVLEREKQVFQVNPNSQPDLDPYTYLVERQLKPEARTDVRTLLHALEIKPTSMIDIS
DGLSSEIIHLCKQSKVGCNLYEDKLPLDPQFISTCEEFNIDSTTVAINGGEDYELLFTIDINDFDKIKGNPNFSIIGHMA
DESEGIHLVTRANTKIALKARGWDALSE
>Mature_348_residues
MIEDKNPQRTSISQLGEFGLIEHLTRNFDVTQESTLKSIGDDAAVLDFKDKKTVISTDLLIEGVHFDLAYMPLKHLGYKA
VIVNLSDICAMNAKPTQITVSVAVSNRFPLEALEELFEGITHAAKEYKVDVIGGDTTSSQKGLIISITAIGEADENEIAY
RNGAKQTDLLVVTGDIGAAYMGLQVLEREKQVFQVNPNSQPDLDPYTYLVERQLKPEARTDVRTLLHALEIKPTSMIDIS
DGLSSEIIHLCKQSKVGCNLYEDKLPLDPQFISTCEEFNIDSTTVAINGGEDYELLFTIDINDFDKIKGNPNFSIIGHMA
DESEGIHLVTRANTKIALKARGWDALSE

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=338, Percent_Identity=33.4319526627219, Blast_Score=132, Evalue=4e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 38450; Mature: 38450

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEDKNPQRTSISQLGEFGLIEHLTRNFDVTQESTLKSIGDDAAVLDFKDKKTVISTDLL
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCEEEEEECCCCEEEEEEHE
IEGVHFDLAYMPLKHLGYKAVIVNLSDICAMNAKPTQITVSVAVSNRFPLEALEELFEGI
EECCEEEHEEHHHHHCCEEEEEEEHHHHHCCCCCCCEEEEEEEECCCCCHHHHHHHHHHH
THAAKEYKVDVIGGDTTSSQKGLIISITAIGEADENEIAYRNGAKQTDLLVVTGDIGAAY
HHHHHHEEEEEEECCCCCCCCCEEEEEEEECCCCCCCEEECCCCCCCEEEEEECCCCHHH
MGLQVLEREKQVFQVNPNSQPDLDPYTYLVERQLKPEARTDVRTLLHALEIKPTSMIDIS
HHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEC
DGLSSEIIHLCKQSKVGCNLYEDKLPLDPQFISTCEEFNIDSTTVAINGGEDYELLFTID
CCCHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHCCCCCEEEEEECCCCEEEEEEEE
INDFDKIKGNPNFSIIGHMADESEGIHLVTRANTKIALKARGWDALSE
CCCHHHCCCCCCEEEEEEECCCCCCEEEEEECCCEEEEEECCCCCCCC
>Mature Secondary Structure
MIEDKNPQRTSISQLGEFGLIEHLTRNFDVTQESTLKSIGDDAAVLDFKDKKTVISTDLL
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCEEEEEECCCCEEEEEEHE
IEGVHFDLAYMPLKHLGYKAVIVNLSDICAMNAKPTQITVSVAVSNRFPLEALEELFEGI
EECCEEEHEEHHHHHCCEEEEEEEHHHHHCCCCCCCEEEEEEEECCCCCHHHHHHHHHHH
THAAKEYKVDVIGGDTTSSQKGLIISITAIGEADENEIAYRNGAKQTDLLVVTGDIGAAY
HHHHHHEEEEEEECCCCCCCCCEEEEEEEECCCCCCCEEECCCCCCCEEEEEECCCCHHH
MGLQVLEREKQVFQVNPNSQPDLDPYTYLVERQLKPEARTDVRTLLHALEIKPTSMIDIS
HHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEC
DGLSSEIIHLCKQSKVGCNLYEDKLPLDPQFISTCEEFNIDSTTVAINGGEDYELLFTID
CCCHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHCCCCCEEEEEECCCCEEEEEEEE
INDFDKIKGNPNFSIIGHMADESEGIHLVTRANTKIALKARGWDALSE
CCCHHHCCCCCCEEEEEEECCCCCCEEEEEECCCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]