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The map label for this gene is occM [H]

Identifier: 146284417

GI number: 146284417

Start: 4459969

End: 4460658

Strand: Direct

Name: occM [H]

Synonym: PST_4106

Alternate gene names: 146284417

Gene position: 4459969-4460658 (Clockwise)

Preceding gene: 146284416

Following gene: 146284418

Centisome position: 97.65

GC content: 64.49

Gene sequence:

>690_bases
ATGACCTGGGAAATCTTCATCAAATGGCTGCCGAGCTTCATCGACGGCGCCTGGCTGACCCTGCAACTGGTCGGCGTGTC
GGTCATCACCGGACTGATCCTCGCCGTACCGCTGGGCATTGCCCGTTCTTCCCGGCACCTGGCGGTGCGGGCATTGCCTT
ACGGCTACATCTTCTTCTTCCGCGGCACGCCGTTGCTGGTCCAGCTGTTTCTCGTGTACTACGGCATGGCGCAGTTCGAC
ATCGTGCGCCAAAGCGCGCTCTGGCCGTACCTGCGTGACCCCTACTGGTGCGCGATCATCACCATGACGCTGCACACCGC
GGCCTACATCGCCGAGATCATCCGCGGCGCGATCCAGAACGTGCCCCATGGCGAAGTCGAAGCCGCCCGCGCGCTGGGCA
TGTCGCGCAGCCAGGCACTGCTGCACATCATCCTGCCGCGCGCTACGCGCATCGGCCTGCCGGCCTACAGCAACGAGGTG
ATCCTGATGCTCAAGGCCAGCGCGCTGGCCAGCACCATCACCCTGCTGGAACTGACCGGCATGGCGCGCAAGATCGCCGC
CCGCACCTACCTGCACGAGGAAATGTTCCTCACCGCCGGCCTGATCTATCTGCTGATCGCCTTCGTGCTGATGCAGGGCT
TCAAACTGCTGGAGCGCTGGCTGCGGGTCGACGCCTGCCAGGGACGCTGA

Upstream 100 bases:

>100_bases
TGGTGGCGGCCTTCATTTACCTGTGCCTGACCATCGTTGCCATGATCGGCATGCACTTCCTCGAAAAACGTGCCGGCCGC
GGCTTCGTGCGGAGCGCAGC

Downstream 100 bases:

>100_bases
TTCCCGCACTGCCTCCTTGCGCAAGGAGGCAGTGACCCTTTCTGAATCCCGCCTTTACTCTGCGGTCAGACTCAGATCCC
GAACCCTTACGAGATTCCCC

Product: amino acid ABC transporter, permease protein

Products: ADP; phosphate; L-histidine [Cytoplasm]; ADP; L-ornithine [Cytoplasm]; L-arginine [Cytoplasm]; L-lysine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MTWEIFIKWLPSFIDGAWLTLQLVGVSVITGLILAVPLGIARSSRHLAVRALPYGYIFFFRGTPLLVQLFLVYYGMAQFD
IVRQSALWPYLRDPYWCAIITMTLHTAAYIAEIIRGAIQNVPHGEVEAARALGMSRSQALLHIILPRATRIGLPAYSNEV
ILMLKASALASTITLLELTGMARKIAARTYLHEEMFLTAGLIYLLIAFVLMQGFKLLERWLRVDACQGR

Sequences:

>Translated_229_residues
MTWEIFIKWLPSFIDGAWLTLQLVGVSVITGLILAVPLGIARSSRHLAVRALPYGYIFFFRGTPLLVQLFLVYYGMAQFD
IVRQSALWPYLRDPYWCAIITMTLHTAAYIAEIIRGAIQNVPHGEVEAARALGMSRSQALLHIILPRATRIGLPAYSNEV
ILMLKASALASTITLLELTGMARKIAARTYLHEEMFLTAGLIYLLIAFVLMQGFKLLERWLRVDACQGR
>Mature_228_residues
TWEIFIKWLPSFIDGAWLTLQLVGVSVITGLILAVPLGIARSSRHLAVRALPYGYIFFFRGTPLLVQLFLVYYGMAQFDI
VRQSALWPYLRDPYWCAIITMTLHTAAYIAEIIRGAIQNVPHGEVEAARALGMSRSQALLHIILPRATRIGLPAYSNEVI
LMLKASALASTITLLELTGMARKIAARTYLHEEMFLTAGLIYLLIAFVLMQGFKLLERWLRVDACQGR

Specific function: Component of the octopine active transport system probably consisting of four subunits:Q, M, P and T [H]

COG id: COG4160

COG function: function code E; ABC-type arginine/histidine transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788645, Length=209, Percent_Identity=45.4545454545455, Blast_Score=156, Evalue=1e-39,
Organism=Escherichia coli, GI1787086, Length=213, Percent_Identity=40.8450704225352, Blast_Score=148, Evalue=2e-37,
Organism=Escherichia coli, GI1788226, Length=207, Percent_Identity=41.5458937198068, Blast_Score=132, Evalue=1e-32,
Organism=Escherichia coli, GI1787030, Length=215, Percent_Identity=31.6279069767442, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI1786874, Length=240, Percent_Identity=28.75, Blast_Score=91, Evalue=4e-20,
Organism=Escherichia coli, GI1787087, Length=207, Percent_Identity=28.0193236714976, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1786873, Length=205, Percent_Identity=29.7560975609756, Blast_Score=87, Evalue=7e-19,
Organism=Escherichia coli, GI1788646, Length=213, Percent_Identity=31.4553990610329, Blast_Score=85, Evalue=3e-18,
Organism=Escherichia coli, GI87082239, Length=206, Percent_Identity=29.6116504854369, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI48994930, Length=101, Percent_Identity=36.6336633663366, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 25754; Mature: 25623

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTWEIFIKWLPSFIDGAWLTLQLVGVSVITGLILAVPLGIARSSRHLAVRALPYGYIFFF
CCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEE
RGTPLLVQLFLVYYGMAQFDIVRQSALWPYLRDPYWCAIITMTLHTAAYIAEIIRGAIQN
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
VPHGEVEAARALGMSRSQALLHIILPRATRIGLPAYSNEVILMLKASALASTITLLELTG
CCCCHHHHHHHHCCCHHHHHHHHHHCCHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHHH
MARKIAARTYLHEEMFLTAGLIYLLIAFVLMQGFKLLERWLRVDACQGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TWEIFIKWLPSFIDGAWLTLQLVGVSVITGLILAVPLGIARSSRHLAVRALPYGYIFFF
CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEE
RGTPLLVQLFLVYYGMAQFDIVRQSALWPYLRDPYWCAIITMTLHTAAYIAEIIRGAIQN
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
VPHGEVEAARALGMSRSQALLHIILPRATRIGLPAYSNEVILMLKASALASTITLLELTG
CCCCHHHHHHHHCCCHHHHHHHHHHCCHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHHH
MARKIAARTYLHEEMFLTAGLIYLLIAFVLMQGFKLLERWLRVDACQGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-histidine [Periplasm]; H2O; ATP; L-ornithine [Periplasm]; L-arginine [Periplasm]; L-lysine [Periplasm] [C]

Specific reaction: ATP + L-histidine [Periplasm] + H2O = ADP + phosphate + L-histidine [Cytoplasm] ATP + L-ornithine [Periplasm] + H2O = ADP + phosphate + L-ornithine [Cytoplasm] ATP + L-arginine [Periplasm] + H2O = ADP + phosphate + L-arginine [Cytoplasm] ATP + L-lysine [P

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1655707; 1732218 [H]