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The map label for this gene is qor [H]

Identifier: 146284388

GI number: 146284388

Start: 4431786

End: 4432871

Strand: Direct

Name: qor [H]

Synonym: PST_4076

Alternate gene names: 146284388

Gene position: 4431786-4432871 (Clockwise)

Preceding gene: 146284385

Following gene: 146284392

Centisome position: 97.03

GC content: 65.75

Gene sequence:

>1086_bases
ATGCTGATTGCCTCGCCACGTAGCGCTCCTAGACTGAAAGCCCTGAGCAGTCGAGCCATCCCATGTCGGGCGGCAAGCGT
CCGACCAGTCGAACAAGGAAAAGCGATGAAAGCCGTCCTGTGCAAAAGCTTCGGCCCGCCCGAAAGCCTGGTTGTCGAAG
ATGCCCCCTCCCCTCAGATCAAACCGAGCGAGATCCTGCTCGACGTGCATGCTGCCGGGGTCAATTTCCCGGACACGTTG
ATGATCGAGGGCAAATACCAGTTCAAGCCGCCGTTTCCGTTTTCGCCCGGCGGCGAGGCGGCCGGCGTGGTCGCTGCGGT
CGGCGAAAAAGTCAGTCACCTGAAGGTGGGCGACCGGGTCATGGCGCTGACCGGCTGGGGCAGCTTCGCCGAGCAGGTGG
CGGTGGCCGGCAGCAACGCGCTGCCGATTCCGCCGAGCATGGACTTCGCCACCGCTGCTGCCTTCAGCATGACCTACGGC
ACCTCGATGCACGCGCTCAAGCAGCGCGCCAGCCTGCAGCCCGGTGAAACCCTGCTGGTACTGGGCGCCTCCGGTGGTGT
CGGCTTGGCTGCCGTGGAGATCGGCAAGGCCGTGGGCGCCCGGGTGATTGCCGCGGCCTCCAGCGCCGAGAAGCTGGAGG
TGGCGAGGAATGCCGGCGCCGACGAGCTGATCAACTACAGCGAAGTGAGCCTGAAGGAGCGGCTGAAGGAACTTACCGGC
GGTCAGGGCGTGGATGTGATCTACGACCCGGTGGGCGGCAAGCTGTTCGAGGAAGCCTTCCGCAGCATCGCCTGGAACGG
CCGCATGCTGGTGGTCGGCTTTGCCGCCGGCGGCGATATTCCGGCACTACCGGCCAACCTGCCGCTGCTCAAGGGTGCGG
CACTGATCGGCGTGTTCTGGGGCGCCTTCGCCCAACGCCAGCCGCAGGACAACGCTGCGAATTTCCGCCAGCTGTTCGCC
TGGCACGCCGAAGGCAAGCTCAAGCCGCTGGTGTCGCAACGCTTCACGCTGGAGGAAGCCGGCCAGGCCATCGCCACGCT
GGGTCAGCGCAAGGCAGTGGGCAAGCTGGTGGTGCAGGTGCGCTAA

Upstream 100 bases:

>100_bases
GGCTCCAGAGAGGAAACCCTGCCAGCATAACCAGTCACAGCACAACGCCCAAGCCGTTGCACTACCGCCTGCCACTTATA
CGCCGCCATTACAGCGAGCG

Downstream 100 bases:

>100_bases
GAACGCACCTAGGGGACTGCAGGAAGCGTCAGACGCTTCCTGCACGATCCGATCGGATCAATGGGCGGTGGCGGGTGCCT
CGCCGGCGCTCTGCATGCGC

Product: oxidoreductase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MLIASPRSAPRLKALSSRAIPCRAASVRPVEQGKAMKAVLCKSFGPPESLVVEDAPSPQIKPSEILLDVHAAGVNFPDTL
MIEGKYQFKPPFPFSPGGEAAGVVAAVGEKVSHLKVGDRVMALTGWGSFAEQVAVAGSNALPIPPSMDFATAAAFSMTYG
TSMHALKQRASLQPGETLLVLGASGGVGLAAVEIGKAVGARVIAAASSAEKLEVARNAGADELINYSEVSLKERLKELTG
GQGVDVIYDPVGGKLFEEAFRSIAWNGRMLVVGFAAGGDIPALPANLPLLKGAALIGVFWGAFAQRQPQDNAANFRQLFA
WHAEGKLKPLVSQRFTLEEAGQAIATLGQRKAVGKLVVQVR

Sequences:

>Translated_361_residues
MLIASPRSAPRLKALSSRAIPCRAASVRPVEQGKAMKAVLCKSFGPPESLVVEDAPSPQIKPSEILLDVHAAGVNFPDTL
MIEGKYQFKPPFPFSPGGEAAGVVAAVGEKVSHLKVGDRVMALTGWGSFAEQVAVAGSNALPIPPSMDFATAAAFSMTYG
TSMHALKQRASLQPGETLLVLGASGGVGLAAVEIGKAVGARVIAAASSAEKLEVARNAGADELINYSEVSLKERLKELTG
GQGVDVIYDPVGGKLFEEAFRSIAWNGRMLVVGFAAGGDIPALPANLPLLKGAALIGVFWGAFAQRQPQDNAANFRQLFA
WHAEGKLKPLVSQRFTLEEAGQAIATLGQRKAVGKLVVQVR
>Mature_361_residues
MLIASPRSAPRLKALSSRAIPCRAASVRPVEQGKAMKAVLCKSFGPPESLVVEDAPSPQIKPSEILLDVHAAGVNFPDTL
MIEGKYQFKPPFPFSPGGEAAGVVAAVGEKVSHLKVGDRVMALTGWGSFAEQVAVAGSNALPIPPSMDFATAAAFSMTYG
TSMHALKQRASLQPGETLLVLGASGGVGLAAVEIGKAVGARVIAAASSAEKLEVARNAGADELINYSEVSLKERLKELTG
GQGVDVIYDPVGGKLFEEAFRSIAWNGRMLVVGFAAGGDIPALPANLPLLKGAALIGVFWGAFAQRQPQDNAANFRQLFA
WHAEGKLKPLVSQRFTLEEAGQAIATLGQRKAVGKLVVQVR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=328, Percent_Identity=33.5365853658537, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI13236495, Length=328, Percent_Identity=33.5365853658537, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI18379349, Length=319, Percent_Identity=31.0344827586207, Blast_Score=145, Evalue=4e-35,
Organism=Homo sapiens, GI194239676, Length=205, Percent_Identity=39.0243902439024, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI22538446, Length=330, Percent_Identity=30.3030303030303, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI22538444, Length=330, Percent_Identity=30.3030303030303, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI24308257, Length=349, Percent_Identity=26.9340974212034, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI28557745, Length=327, Percent_Identity=31.4984709480122, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI41872631, Length=313, Percent_Identity=28.4345047923323, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI47519420, Length=376, Percent_Identity=28.1914893617021, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI197927207, Length=181, Percent_Identity=31.4917127071823, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI67078404, Length=265, Percent_Identity=27.5471698113208, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI67078406, Length=254, Percent_Identity=28.3464566929134, Blast_Score=81, Evalue=1e-15,
Organism=Escherichia coli, GI1790485, Length=318, Percent_Identity=34.9056603773585, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1789651, Length=257, Percent_Identity=26.0700389105058, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI226510941, Length=294, Percent_Identity=26.8707482993197, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87081918, Length=335, Percent_Identity=26.5671641791045, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17507255, Length=327, Percent_Identity=30.2752293577982, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17536829, Length=354, Percent_Identity=28.5310734463277, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI71988145, Length=222, Percent_Identity=27.027027027027, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI212642053, Length=308, Percent_Identity=25.974025974026, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI133901710, Length=292, Percent_Identity=25.6849315068493, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI133901712, Length=292, Percent_Identity=25.6849315068493, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71987554, Length=359, Percent_Identity=25.6267409470752, Blast_Score=71, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6319520, Length=334, Percent_Identity=28.1437125748503, Blast_Score=123, Evalue=5e-29,
Organism=Saccharomyces cerevisiae, GI6323961, Length=305, Percent_Identity=26.8852459016393, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6319621, Length=339, Percent_Identity=25.9587020648968, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6324486, Length=308, Percent_Identity=26.9480519480519, Blast_Score=82, Evalue=9e-17,
Organism=Drosophila melanogaster, GI45550423, Length=324, Percent_Identity=26.5432098765432, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI221330659, Length=311, Percent_Identity=26.0450160771704, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24581345, Length=323, Percent_Identity=26.0061919504644, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI19920632, Length=311, Percent_Identity=26.0450160771704, Blast_Score=82, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 37729; Mature: 37729

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIASPRSAPRLKALSSRAIPCRAASVRPVEQGKAMKAVLCKSFGPPESLVVEDAPSPQI
CEECCCCCCCHHHHHHCCCCCCCCCCCCCHHHCHHHHHHHHHCCCCCCCEEEECCCCCCC
KPSEILLDVHAAGVNFPDTLMIEGKYQFKPPFPFSPGGEAAGVVAAVGEKVSHLKVGDRV
CHHHEEEEEEECCCCCCCEEEEECEEEECCCCCCCCCCCCCHHHHHHHHHHHHEECCCEE
MALTGWGSFAEQVAVAGSNALPIPPSMDFATAAAFSMTYGTSMHALKQRASLQPGETLLV
EEEECCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEE
LGASGGVGLAAVEIGKAVGARVIAAASSAEKLEVARNAGADELINYSEVSLKERLKELTG
EECCCCCCCHHHHHHHHHHHHHEEECCCHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHCC
GQGVDVIYDPVGGKLFEEAFRSIAWNGRMLVVGFAAGGDIPALPANLPLLKGAALIGVFW
CCCCEEEEECCCCHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHH
GAFAQRQPQDNAANFRQLFAWHAEGKLKPLVSQRFTLEEAGQAIATLGQRKAVGKLVVQV
HHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCEEEEEEE
R
C
>Mature Secondary Structure
MLIASPRSAPRLKALSSRAIPCRAASVRPVEQGKAMKAVLCKSFGPPESLVVEDAPSPQI
CEECCCCCCCHHHHHHCCCCCCCCCCCCCHHHCHHHHHHHHHCCCCCCCEEEECCCCCCC
KPSEILLDVHAAGVNFPDTLMIEGKYQFKPPFPFSPGGEAAGVVAAVGEKVSHLKVGDRV
CHHHEEEEEEECCCCCCCEEEEECEEEECCCCCCCCCCCCCHHHHHHHHHHHHEECCCEE
MALTGWGSFAEQVAVAGSNALPIPPSMDFATAAAFSMTYGTSMHALKQRASLQPGETLLV
EEEECCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEE
LGASGGVGLAAVEIGKAVGARVIAAASSAEKLEVARNAGADELINYSEVSLKERLKELTG
EECCCCCCCHHHHHHHHHHHHHEEECCCHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHCC
GQGVDVIYDPVGGKLFEEAFRSIAWNGRMLVVGFAAGGDIPALPANLPLLKGAALIGVFW
CCCCEEEEECCCCHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHH
GAFAQRQPQDNAANFRQLFAWHAEGKLKPLVSQRFTLEEAGQAIATLGQRKAVGKLVVQV
HHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCEEEEEEE
R
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]