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The map label for this gene is ygfA [C]

Identifier: 146284385

GI number: 146284385

Start: 4429840

End: 4430445

Strand: Direct

Name: ygfA [C]

Synonym: PST_4073

Alternate gene names: 146284385

Gene position: 4429840-4430445 (Clockwise)

Preceding gene: 146284384

Following gene: 146284388

Centisome position: 96.99

GC content: 67.0

Gene sequence:

>606_bases
ATGATCGTAGCCGAAGGCCTCTCGCGCCCGGCGCTGCGTCGCAAGCTGCGCCAGACCCGGCGCCAACTCTCTCCCGCCCA
GCAACGCCACGCCGCCCGCCGCCTTTACCGGCAACTCAGCCATCACCCGCTCTTTCGTCGCGCCCGGCATATCGCCCTGT
ATCTGCCCAACGACGGCGAGATCGATCCACGCCTGCTGCTGCGCGCCGCGCAACGCCGGGGCAAGGCGACCTATCTGCCG
GTACTCAACCCATGGCCGCGCACGCGCATGGTGTTCCAGCGCATCGAGCCCGGCGAGCGACTGCGGCGCAACCGCTTCGG
CATCTTCGAACCCGTGATTCGAACCGCTCGACAGCGTCGCGTCTGGGCGCTGGACCTGCTGTTGATGCCATTGGTGGGTT
TCGATGGGAATGGCGGGCGGCTGGGCATGGGCGGCGGGTTCTATGATCGCAGCCTCGCGTACCGCGCCAGGCGCAAAAAA
AGTCACAAACCGACGCTTCTGGGCCTGGCCCATGAATGCCAGCGAGTCGATCGACTGCCGCTGGAGAGCTGGGATGTACC
CCTGCTGGGTACGGTGACGGACCGGGGCTGGTACGTCGAGCGCTGA

Upstream 100 bases:

>100_bases
TCCGCCTGACGGAAAGCCTTAAGGTACTCTGTAGTCGCCACCTTGAACTCTCGGGTTCAAGGGCCTACGCTGGCAGCGGC
ATGCTGGGGAGCCACTTCCG

Downstream 100 bases:

>100_bases
AACGCCGCGTCCATGCGGCGCTCGGTCAGCGTTGCTGGGTCTGCTGCACCTGGATCACCGGGGCCATGCCCGCGGCGCCG
TCGTTGCGCTCCCACAGGCT

Product: 5-formyltetrahydrofolate cyclo-ligase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MIVAEGLSRPALRRKLRQTRRQLSPAQQRHAARRLYRQLSHHPLFRRARHIALYLPNDGEIDPRLLLRAAQRRGKATYLP
VLNPWPRTRMVFQRIEPGERLRRNRFGIFEPVIRTARQRRVWALDLLLMPLVGFDGNGGRLGMGGGFYDRSLAYRARRKK
SHKPTLLGLAHECQRVDRLPLESWDVPLLGTVTDRGWYVER

Sequences:

>Translated_201_residues
MIVAEGLSRPALRRKLRQTRRQLSPAQQRHAARRLYRQLSHHPLFRRARHIALYLPNDGEIDPRLLLRAAQRRGKATYLP
VLNPWPRTRMVFQRIEPGERLRRNRFGIFEPVIRTARQRRVWALDLLLMPLVGFDGNGGRLGMGGGFYDRSLAYRARRKK
SHKPTLLGLAHECQRVDRLPLESWDVPLLGTVTDRGWYVER
>Mature_201_residues
MIVAEGLSRPALRRKLRQTRRQLSPAQQRHAARRLYRQLSHHPLFRRARHIALYLPNDGEIDPRLLLRAAQRRGKATYLP
VLNPWPRTRMVFQRIEPGERLRRNRFGIFEPVIRTARQRRVWALDLLLMPLVGFDGNGGRLGMGGGFYDRSLAYRARRKK
SHKPTLLGLAHECQRVDRLPLESWDVPLLGTVTDRGWYVER

Specific function: Unknown

COG id: COG0212

COG function: function code H; 5-formyltetrahydrofolate cyclo-ligase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family [H]

Homologues:

Organism=Homo sapiens, GI5453746, Length=183, Percent_Identity=27.8688524590164, Blast_Score=73, Evalue=1e-13,
Organism=Escherichia coli, GI1789278, Length=178, Percent_Identity=39.8876404494382, Blast_Score=132, Evalue=2e-32,
Organism=Drosophila melanogaster, GI161077430, Length=193, Percent_Identity=27.4611398963731, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002698 [H]

Pfam domain/function: PF01812 5-FTHF_cyc-lig [H]

EC number: NA

Molecular weight: Translated: 23580; Mature: 23580

Theoretical pI: Translated: 12.24; Mature: 12.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVAEGLSRPALRRKLRQTRRQLSPAQQRHAARRLYRQLSHHPLFRRARHIALYLPNDGE
CCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHCEEEEECCCCCC
IDPRLLLRAAQRRGKATYLPVLNPWPRTRMVFQRIEPGERLRRNRFGIFEPVIRTARQRR
CCHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHH
VWALDLLLMPLVGFDGNGGRLGMGGGFYDRSLAYRARRKKSHKPTLLGLAHECQRVDRLP
HHHHHHHHHHHHCCCCCCCEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
LESWDVPLLGTVTDRGWYVER
CCCCCCCEEEEECCCCEEECC
>Mature Secondary Structure
MIVAEGLSRPALRRKLRQTRRQLSPAQQRHAARRLYRQLSHHPLFRRARHIALYLPNDGE
CCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHCEEEEECCCCCC
IDPRLLLRAAQRRGKATYLPVLNPWPRTRMVFQRIEPGERLRRNRFGIFEPVIRTARQRR
CCHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHH
VWALDLLLMPLVGFDGNGGRLGMGGGFYDRSLAYRARRKKSHKPTLLGLAHECQRVDRLP
HHHHHHHHHHHHCCCCCCCEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
LESWDVPLLGTVTDRGWYVER
CCCCCCCEEEEECCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]