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The map label for this gene is evgS [H]

Identifier: 146284300

GI number: 146284300

Start: 4324225

End: 4326618

Strand: Direct

Name: evgS [H]

Synonym: PST_3988

Alternate gene names: 146284300

Gene position: 4324225-4326618 (Clockwise)

Preceding gene: 146284299

Following gene: 146284305

Centisome position: 94.68

GC content: 66.75

Gene sequence:

>2394_bases
ATGCTGGGCGAGAAGGTCACCGAGGCGATCCGCAAGCGCCTGCGCGACCATGAACAGATCCTGCTCGGCGGCGCCGGCCT
GTTCGACGCGGTGGAGCAGGTCAGCCGCGAACAATGGCGGCTGTACGTCGAACGACTGGCCCTGGCCGAGCGTTATCCGG
GCATCCAGGGCGTCGGCTTCACCCAGGCCATCCGTCCTGCTGAGCGAGCCGCTCATGTGGCGCGCATCCGCTCCCAGGGC
TTTGCCGATTACGACATCCACCCAGCTGGCGAGCGCGAGCTGTACACCTCGATCATCTTTCTGGAACCGTTCAGCGGGCG
CAACCTGGCGGCCTTCGGCTACGACATGTACGCCGAACCGATACGTCAGCAGGCCATGCAGCGCGCGGCGCAGCTCGGCG
AGACCAGCATCACCGGCAAGGTGACGCTGGTACAGGAGACCCATGGCACGGTCCAGGCCGGGGTGCTGCTCTATGTGCCC
GTGCATCGTCCGCACCTGCCGACAAGCACGCCGGACGAGCGCATGCAGGCGCTGCTCGGCTTCGTCTACAGCCCCTATCG
GGTCGACGACCTGATGCGCGGTATCCTCCGCGCCGCCGACCTGCCGCTGGCGCTGCACATCTACGCCAGCGCCGACGAGG
CGCCCGAGCATCTGCTGCACGCCTCGCGTGAGGCACCCGCCCCCGGCAGCGCGCGCTACAGCGCGCTGCAGCGACTCGAA
CTGTACGGCCAGACCTGGACGCTGCGCATGGACAGTCGCCCCGAGTTCGAGGATCGCTTCCATGCCAACGAGGCGCTGGT
ATTCGGCCTCGGCGTCGGCCTCAGCCTGCTGGTGTTCTTTCTCACCTCGTCACTGGCGCTGCGTCACGGCCGCGCCCAGG
CCCTGGCCGAGGAAATGACGCGGCATATCCGGCAGAGCCGGCACGACCTGCGGCTGAGCGAGGAACGTCTGTCGCTGGCG
CTCAAGGGCAGCAACGACGGGCTCTGGGACCTGGACCTGGAAGCCGGCAGCATGTACGCCTCGCCCCGCGCCTGGGAAAT
GCTCGGCTATCGCCCCAACGAGCTGCCCTGCGACCTCAAGCTGTGGGAGCGGGTGACCGTCGCCGAGGATCTTGCCCAGC
AGAAAGCCAGATTGGCGCAGACGATGCTCGCCAACGTCGACCACTTCACCACCGAGTTGCGCCTGCTGCACAAGCACGGC
CATGTCGTGCCGGTGCTGCTGCGCGGCTACATCCAGCGCGACCCGCAGGGCATGGCCCAGCGCATCAGCGGCACGCTGAT
GGACCTGACCGAACGCAAGCGCATCGAGCAGATGAAGAACGACTTCGTCTCCACCGTCAGCCACGAGCTGCGTACACCGC
TGACCTCGATCAGCGGGGCGCTGGGGCTGATCGTCGGTGGCGCGCTCGGCAAGGCGCCGCCGTCCATGCAGCAGATGCTG
GAAATCGCCTACAGCAACAGCCTGCGCCTGGGCCATCTGATCAACGACCTGCTGGACATGGAGAAGATCGCCGCCGGCAA
GATGAGCTTCGAACTGCGCGAACACTCGCTCGGCGAGCTGCTCAAGGAATCCCTGGCGAGCAATCAGGCGCTATGCGATC
AGCACGGCGTGCGCTGCAGCCTGGAGCACGCCACTGACGTGCGGGTCTGGGTGGATGGCATGCGCCTGCAGCAGGTGCTC
GGCAATTTCCTGTCCAACGCCTTCAAATTCACTCCGGCGGGTGGTCACATCCGCGTCCACAGCAGCCTGCGCGGCCAGCG
CGTGCGCATCAGCGTCACCGATCAGGGACCGGGTATTCCCGAAGCGTTCCGCTCGCGGGTGTTCGAGAAATTCGCCCAGG
CCGATGCCTCCGACAGCCGGCAGAAATCCGGCACCGGCCTGGGTCTGGCCATTACCAAGGAGCTGATCGAGCGCATGGGC
GGCACGGTGGGCTTCGATTGCGAGCCGGGCCAGGGCACGACCTTCTGGTGCGAGCTGCCGATCCAGCTGCCCTCCGCCGA
GACCGACGGCGGCGGAGATCTGCCACGCATTCTGGTGGTCGAGGACGAGCCGGACACCGGCCGCCTGTTGCATCTGATGC
TGCGCGAAGGCGGTTACGCCGCGGACCGCGTGCAGAGCCTGCACCAGGCCAGGGAAAAGCTCGCCAGCGAGCATTACGAA
GCCATGACCCTCGACCTGCACCTGCCTGATGGCAGCGGCATGCAGTTGATCGCCGAACTGCGCGACAAGCCCGTGCTGCA
GGATCTGCCCATCGTGGTCATCTCCGCCGCCCACCAGTTCGACCGCGCGCAGTTCCCGGAAGAGATCGTCTGGCTGCACA
AACCGATCACCAATGCGCAATTGCTGGCCGCGGTCGAGAAAGCGCGTGGGCACCGCCGTCCCGGCAGCCCGTGA

Upstream 100 bases:

>100_bases
TATCGCCTGGGGCATGCTGGTGTTCACGCTGCTGGTGCAGCTGGTCGTCTGGCAGAGCCTGCGTGCCAATGAGGACCGGG
CCGCCCAGGAGCAGTTCCAG

Downstream 100 bases:

>100_bases
TCACAGTCTGAAGATGACAGGCAAAAAAAATCGCGGGAGCCGTCGGCATCCCGCGATTCATTTCTGCTGAAGGGTGTCAG
GCCTGGATCGAGCCCTTGAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 797; Mature: 797

Protein sequence:

>797_residues
MLGEKVTEAIRKRLRDHEQILLGGAGLFDAVEQVSREQWRLYVERLALAERYPGIQGVGFTQAIRPAERAAHVARIRSQG
FADYDIHPAGERELYTSIIFLEPFSGRNLAAFGYDMYAEPIRQQAMQRAAQLGETSITGKVTLVQETHGTVQAGVLLYVP
VHRPHLPTSTPDERMQALLGFVYSPYRVDDLMRGILRAADLPLALHIYASADEAPEHLLHASREAPAPGSARYSALQRLE
LYGQTWTLRMDSRPEFEDRFHANEALVFGLGVGLSLLVFFLTSSLALRHGRAQALAEEMTRHIRQSRHDLRLSEERLSLA
LKGSNDGLWDLDLEAGSMYASPRAWEMLGYRPNELPCDLKLWERVTVAEDLAQQKARLAQTMLANVDHFTTELRLLHKHG
HVVPVLLRGYIQRDPQGMAQRISGTLMDLTERKRIEQMKNDFVSTVSHELRTPLTSISGALGLIVGGALGKAPPSMQQML
EIAYSNSLRLGHLINDLLDMEKIAAGKMSFELREHSLGELLKESLASNQALCDQHGVRCSLEHATDVRVWVDGMRLQQVL
GNFLSNAFKFTPAGGHIRVHSSLRGQRVRISVTDQGPGIPEAFRSRVFEKFAQADASDSRQKSGTGLGLAITKELIERMG
GTVGFDCEPGQGTTFWCELPIQLPSAETDGGGDLPRILVVEDEPDTGRLLHLMLREGGYAADRVQSLHQAREKLASEHYE
AMTLDLHLPDGSGMQLIAELRDKPVLQDLPIVVISAAHQFDRAQFPEEIVWLHKPITNAQLLAAVEKARGHRRPGSP

Sequences:

>Translated_797_residues
MLGEKVTEAIRKRLRDHEQILLGGAGLFDAVEQVSREQWRLYVERLALAERYPGIQGVGFTQAIRPAERAAHVARIRSQG
FADYDIHPAGERELYTSIIFLEPFSGRNLAAFGYDMYAEPIRQQAMQRAAQLGETSITGKVTLVQETHGTVQAGVLLYVP
VHRPHLPTSTPDERMQALLGFVYSPYRVDDLMRGILRAADLPLALHIYASADEAPEHLLHASREAPAPGSARYSALQRLE
LYGQTWTLRMDSRPEFEDRFHANEALVFGLGVGLSLLVFFLTSSLALRHGRAQALAEEMTRHIRQSRHDLRLSEERLSLA
LKGSNDGLWDLDLEAGSMYASPRAWEMLGYRPNELPCDLKLWERVTVAEDLAQQKARLAQTMLANVDHFTTELRLLHKHG
HVVPVLLRGYIQRDPQGMAQRISGTLMDLTERKRIEQMKNDFVSTVSHELRTPLTSISGALGLIVGGALGKAPPSMQQML
EIAYSNSLRLGHLINDLLDMEKIAAGKMSFELREHSLGELLKESLASNQALCDQHGVRCSLEHATDVRVWVDGMRLQQVL
GNFLSNAFKFTPAGGHIRVHSSLRGQRVRISVTDQGPGIPEAFRSRVFEKFAQADASDSRQKSGTGLGLAITKELIERMG
GTVGFDCEPGQGTTFWCELPIQLPSAETDGGGDLPRILVVEDEPDTGRLLHLMLREGGYAADRVQSLHQAREKLASEHYE
AMTLDLHLPDGSGMQLIAELRDKPVLQDLPIVVISAAHQFDRAQFPEEIVWLHKPITNAQLLAAVEKARGHRRPGSP
>Mature_797_residues
MLGEKVTEAIRKRLRDHEQILLGGAGLFDAVEQVSREQWRLYVERLALAERYPGIQGVGFTQAIRPAERAAHVARIRSQG
FADYDIHPAGERELYTSIIFLEPFSGRNLAAFGYDMYAEPIRQQAMQRAAQLGETSITGKVTLVQETHGTVQAGVLLYVP
VHRPHLPTSTPDERMQALLGFVYSPYRVDDLMRGILRAADLPLALHIYASADEAPEHLLHASREAPAPGSARYSALQRLE
LYGQTWTLRMDSRPEFEDRFHANEALVFGLGVGLSLLVFFLTSSLALRHGRAQALAEEMTRHIRQSRHDLRLSEERLSLA
LKGSNDGLWDLDLEAGSMYASPRAWEMLGYRPNELPCDLKLWERVTVAEDLAQQKARLAQTMLANVDHFTTELRLLHKHG
HVVPVLLRGYIQRDPQGMAQRISGTLMDLTERKRIEQMKNDFVSTVSHELRTPLTSISGALGLIVGGALGKAPPSMQQML
EIAYSNSLRLGHLINDLLDMEKIAAGKMSFELREHSLGELLKESLASNQALCDQHGVRCSLEHATDVRVWVDGMRLQQVL
GNFLSNAFKFTPAGGHIRVHSSLRGQRVRISVTDQGPGIPEAFRSRVFEKFAQADASDSRQKSGTGLGLAITKELIERMG
GTVGFDCEPGQGTTFWCELPIQLPSAETDGGGDLPRILVVEDEPDTGRLLHLMLREGGYAADRVQSLHQAREKLASEHYE
AMTLDLHLPDGSGMQLIAELRDKPVLQDLPIVVISAAHQFDRAQFPEEIVWLHKPITNAQLLAAVEKARGHRRPGSP

Specific function: Member of the two-component regulatory system evgS/evgA. Phosphorylates evgA via a four-step phosphorelay in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=337, Percent_Identity=30.5637982195846, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI48994928, Length=385, Percent_Identity=31.4285714285714, Blast_Score=149, Evalue=5e-37,
Organism=Escherichia coli, GI1789149, Length=250, Percent_Identity=36.8, Blast_Score=141, Evalue=2e-34,
Organism=Escherichia coli, GI145693157, Length=253, Percent_Identity=36.7588932806324, Blast_Score=139, Evalue=7e-34,
Organism=Escherichia coli, GI87081816, Length=322, Percent_Identity=30.7453416149068, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI1786912, Length=230, Percent_Identity=31.304347826087, Blast_Score=105, Evalue=8e-24,
Organism=Escherichia coli, GI87082128, Length=238, Percent_Identity=34.0336134453782, Blast_Score=105, Evalue=9e-24,
Organism=Escherichia coli, GI1788393, Length=231, Percent_Identity=27.2727272727273, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1786600, Length=246, Percent_Identity=30.4878048780488, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1786783, Length=258, Percent_Identity=26.7441860465116, Blast_Score=90, Evalue=5e-19,
Organism=Escherichia coli, GI1790436, Length=244, Percent_Identity=29.9180327868852, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1787894, Length=237, Percent_Identity=31.6455696202532, Blast_Score=83, Evalue=9e-17,
Organism=Escherichia coli, GI1788549, Length=396, Percent_Identity=22.979797979798, Blast_Score=80, Evalue=7e-16,
Organism=Escherichia coli, GI1790861, Length=226, Percent_Identity=26.5486725663717, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1790346, Length=234, Percent_Identity=27.3504273504274, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1790300, Length=276, Percent_Identity=29.3478260869565, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1789808, Length=236, Percent_Identity=25, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001638
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00072 Response_reg; PF00497 SBP_bac_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 88719; Mature: 88719

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: PS50839 CHASE ; PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGEKVTEAIRKRLRDHEQILLGGAGLFDAVEQVSREQWRLYVERLALAERYPGIQGVGF
CCCHHHHHHHHHHHCCCHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
TQAIRPAERAAHVARIRSQGFADYDIHPAGERELYTSIIFLEPFSGRNLAAFGYDMYAEP
HHHHCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHEEEEEEEECCCCCCEEEECHHHHHHH
IRQQAMQRAAQLGETSITGKVTLVQETHGTVQAGVLLYVPVHRPHLPTSTPDERMQALLG
HHHHHHHHHHHCCCCCCCEEEEEEEECCCCEEECEEEEEECCCCCCCCCCHHHHHHHHHH
FVYSPYRVDDLMRGILRAADLPLALHIYASADEAPEHLLHASREAPAPGSARYSALQRLE
HHCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHCCCCCCCCCHHHHHHHHHHH
LYGQTWTLRMDSRPEFEDRFHANEALVFGLGVGLSLLVFFLTSSLALRHGRAQALAEEMT
HCCCEEEEEECCCCCHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
RHIRQSRHDLRLSEERLSLALKGSNDGLWDLDLEAGSMYASPRAWEMLGYRPNELPCDLK
HHHHHHHHHCCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCCHHHHHCCCCCCCCCCHH
LWERVTVAEDLAQQKARLAQTMLANVDHFTTELRLLHKHGHVVPVLLRGYIQRDPQGMAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHH
RISGTLMDLTERKRIEQMKNDFVSTVSHELRTPLTSISGALGLIVGGALGKAPPSMQQML
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCHHHHHHH
EIAYSNSLRLGHLINDLLDMEKIAAGKMSFELREHSLGELLKESLASNQALCDQHGVRCS
HHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEEE
LEHATDVRVWVDGMRLQQVLGNFLSNAFKFTPAGGHIRVHSSLRGQRVRISVTDQGPGIP
ECCCCCEEEEHHHHHHHHHHHHHHHHCEEECCCCCEEEEECCCCCCEEEEEECCCCCCCH
EAFRSRVFEKFAQADASDSRQKSGTGLGLAITKELIERMGGTVGFDCEPGQGTTFWCELP
HHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHCCCEECCCCCCCCCEEEEEEC
IQLPSAETDGGGDLPRILVVEDEPDTGRLLHLMLREGGYAADRVQSLHQAREKLASEHYE
EECCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCE
AMTLDLHLPDGSGMQLIAELRDKPVLQDLPIVVISAAHQFDRAQFPEEIVWLHKPITNAQ
EEEEEEECCCCCCHHHHHHHHCCCCHHHCCCCEEHHHHHHHHHCCCHHHHHHHCCCCCHH
LLAAVEKARGHRRPGSP
HHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MLGEKVTEAIRKRLRDHEQILLGGAGLFDAVEQVSREQWRLYVERLALAERYPGIQGVGF
CCCHHHHHHHHHHHCCCHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
TQAIRPAERAAHVARIRSQGFADYDIHPAGERELYTSIIFLEPFSGRNLAAFGYDMYAEP
HHHHCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHEEEEEEEECCCCCCEEEECHHHHHHH
IRQQAMQRAAQLGETSITGKVTLVQETHGTVQAGVLLYVPVHRPHLPTSTPDERMQALLG
HHHHHHHHHHHCCCCCCCEEEEEEEECCCCEEECEEEEEECCCCCCCCCCHHHHHHHHHH
FVYSPYRVDDLMRGILRAADLPLALHIYASADEAPEHLLHASREAPAPGSARYSALQRLE
HHCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHCCCCCCCCCHHHHHHHHHHH
LYGQTWTLRMDSRPEFEDRFHANEALVFGLGVGLSLLVFFLTSSLALRHGRAQALAEEMT
HCCCEEEEEECCCCCHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
RHIRQSRHDLRLSEERLSLALKGSNDGLWDLDLEAGSMYASPRAWEMLGYRPNELPCDLK
HHHHHHHHHCCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCCHHHHHCCCCCCCCCCHH
LWERVTVAEDLAQQKARLAQTMLANVDHFTTELRLLHKHGHVVPVLLRGYIQRDPQGMAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHH
RISGTLMDLTERKRIEQMKNDFVSTVSHELRTPLTSISGALGLIVGGALGKAPPSMQQML
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCHHHHHHH
EIAYSNSLRLGHLINDLLDMEKIAAGKMSFELREHSLGELLKESLASNQALCDQHGVRCS
HHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEEE
LEHATDVRVWVDGMRLQQVLGNFLSNAFKFTPAGGHIRVHSSLRGQRVRISVTDQGPGIP
ECCCCCEEEEHHHHHHHHHHHHHHHHCEEECCCCCEEEEECCCCCCEEEEEECCCCCCCH
EAFRSRVFEKFAQADASDSRQKSGTGLGLAITKELIERMGGTVGFDCEPGQGTTFWCELP
HHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHCCCEECCCCCCCCCEEEEEEC
IQLPSAETDGGGDLPRILVVEDEPDTGRLLHLMLREGGYAADRVQSLHQAREKLASEHYE
EECCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCE
AMTLDLHLPDGSGMQLIAELRDKPVLQDLPIVVISAAHQFDRAQFPEEIVWLHKPITNAQ
EEEEEEECCCCCCHHHHHHHHCCCCHHHCCCCEEHHHHHHHHHCCCHHHHHHHCCCCCHH
LLAAVEKARGHRRPGSP
HHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]