Click here to switch to the map view.

The map label for this gene is mtgA

Identifier: 146284298

GI number: 146284298

Start: 4321095

End: 4321823

Strand: Direct

Name: mtgA

Synonym: PST_3986

Alternate gene names: 146284298

Gene position: 4321095-4321823 (Clockwise)

Preceding gene: 146284292

Following gene: 146284299

Centisome position: 94.61

GC content: 64.75

Gene sequence:

>729_bases
ATGTTGCGAAACCTGCTGCTGCGCCTGTCCAAACTGCTGCTCTGGCTGATCGCCCTTTCGGTGCTGCTGGTCCTGCTGCT
GCGCTGGGTGCCGCCGCCCTTCACCGCGTTGATGATCGAGCGCAAGATCGAATCCTGGCGCACCGGCGAGGCGATCGACC
TGACCCGCGAGTGGCGGCCATGGCGCGAGCTGCCCGACGACCTGAAAATGGCCGTGATTGCCGCCGAGGACCAGAAATTC
GCCGACCACTGGGGCTTCGACGTCGCTGCAATCCGCGCTGCCCTCAGCCACAATGAGCGAGGCGGATCACTGCGCGGCGC
CAGCACGCTGAGCCAGCAGGTGGCCAAGAACCTGTTTCTCTGGTCCGGACGCAGCTGGCCGCGCAAGGGACTGGAGGCCT
GGTTCACCGCGCTGATCGAATTGATGTGGCCCAAGCAACGCATTCTCGAGGTCTACCTCAACAGCGTCGAATGGGGCGAC
GGCATCTTCGGTGCGCAGGCGGCGGCGCAGCATCACTTCGGTACCGGTGCGCCCTATCTGTCGGCCCACCAGGCCAGCCT
GCTGGCCGCGGTGCTGCCCAACCCGCGACAATGGAGCGCTGGTAAACCGAGCCGCTATGTGAACAATCGCGCGGCCTGGA
TTCGACAGCAGATGCGCCAGCTCGGTGGCAGCCATTACTTGCAGCGAATCAAACCGAACCACCCGGAATGGTGGCCGAGC
TGGCTGTGA

Upstream 100 bases:

>100_bases
CAGGGCGGCAAGCACGAGATAGCTACGAATCATTGCTTTTCCGGTCGATGGCCTGAGCGGCCGCTATAATGCCCGCTCTT
TTCGCCCACGACCACGTGCC

Downstream 100 bases:

>100_bases
GCCGGCATGCAGCACGACCGGCGCAGCAGGACGCAGCACTACCGGTGCCTGATGACCTAGCGCCCGCTCGCCATGGTGCG
ATGGGGTTTGACTGTGCAGT

Product: monofunctional biosynthetic peptidoglycan transglycosylase

Products: NA

Alternate protein names: Monofunctional TGase

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MLRNLLLRLSKLLLWLIALSVLLVLLLRWVPPPFTALMIERKIESWRTGEAIDLTREWRPWRELPDDLKMAVIAAEDQKF
ADHWGFDVAAIRAALSHNERGGSLRGASTLSQQVAKNLFLWSGRSWPRKGLEAWFTALIELMWPKQRILEVYLNSVEWGD
GIFGAQAAAQHHFGTGAPYLSAHQASLLAAVLPNPRQWSAGKPSRYVNNRAAWIRQQMRQLGGSHYLQRIKPNHPEWWPS
WL

Sequences:

>Translated_242_residues
MLRNLLLRLSKLLLWLIALSVLLVLLLRWVPPPFTALMIERKIESWRTGEAIDLTREWRPWRELPDDLKMAVIAAEDQKF
ADHWGFDVAAIRAALSHNERGGSLRGASTLSQQVAKNLFLWSGRSWPRKGLEAWFTALIELMWPKQRILEVYLNSVEWGD
GIFGAQAAAQHHFGTGAPYLSAHQASLLAAVLPNPRQWSAGKPSRYVNNRAAWIRQQMRQLGGSHYLQRIKPNHPEWWPS
WL
>Mature_242_residues
MLRNLLLRLSKLLLWLIALSVLLVLLLRWVPPPFTALMIERKIESWRTGEAIDLTREWRPWRELPDDLKMAVIAAEDQKF
ADHWGFDVAAIRAALSHNERGGSLRGASTLSQQVAKNLFLWSGRSWPRKGLEAWFTALIELMWPKQRILEVYLNSVEWGD
GIFGAQAAAQHHFGTGAPYLSAHQASLLAAVLPNPRQWSAGKPSRYVNNRAAWIRQQMRQLGGSHYLQRIKPNHPEWWPS
WL

Specific function: Cell wall formation

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 51 family

Homologues:

Organism=Escherichia coli, GI1789601, Length=234, Percent_Identity=50, Blast_Score=215, Evalue=2e-57,
Organism=Escherichia coli, GI1786343, Length=142, Percent_Identity=38.0281690140845, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI87082258, Length=209, Percent_Identity=30.1435406698565, Blast_Score=84, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTGA_PSEU5 (A4VRK8)

Other databases:

- EMBL:   CP000304
- RefSeq:   YP_001174451.1
- ProteinModelPortal:   A4VRK8
- SMR:   A4VRK8
- STRING:   A4VRK8
- GeneID:   5096947
- GenomeReviews:   CP000304_GR
- KEGG:   psa:PST_3986
- eggNOG:   COG0744
- HOGENOM:   HBG685698
- OMA:   ELVWTKR
- PhylomeDB:   A4VRK8
- ProtClustDB:   PRK00056
- BioCyc:   PSTU379731:PST_3986-MONOMER
- HAMAP:   MF_00766
- InterPro:   IPR001264
- InterPro:   IPR011812
- TIGRFAMs:   TIGR02070

Pfam domain/function: PF00912 Transgly

EC number: 2.4.2.- [C]

Molecular weight: Translated: 27824; Mature: 27824

Theoretical pI: Translated: 10.91; Mature: 10.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1f868dc8)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRNLLLRLSKLLLWLIALSVLLVLLLRWVPPPFTALMIERKIESWRTGEAIDLTREWRP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEECHHCCCC
WRELPDDLKMAVIAAEDQKFADHWGFDVAAIRAALSHNERGGSLRGASTLSQQVAKNLFL
HHHCCHHHHEEHHCCCCHHHHHHHCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
WSGRSWPRKGLEAWFTALIELMWPKQRILEVYLNSVEWGDGIFGAQAAAQHHFGTGAPYL
CCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCH
SAHQASLLAAVLPNPRQWSAGKPSRYVNNRAAWIRQQMRQLGGSHYLQRIKPNHPEWWPS
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
WL
CH
>Mature Secondary Structure
MLRNLLLRLSKLLLWLIALSVLLVLLLRWVPPPFTALMIERKIESWRTGEAIDLTREWRP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEECHHCCCC
WRELPDDLKMAVIAAEDQKFADHWGFDVAAIRAALSHNERGGSLRGASTLSQQVAKNLFL
HHHCCHHHHEEHHCCCCHHHHHHHCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
WSGRSWPRKGLEAWFTALIELMWPKQRILEVYLNSVEWGDGIFGAQAAAQHHFGTGAPYL
CCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCH
SAHQASLLAAVLPNPRQWSAGKPSRYVNNRAAWIRQQMRQLGGSHYLQRIKPNHPEWWPS
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
WL
CH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA