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The map label for this gene is arcD-2 [H]

Identifier: 146284289

GI number: 146284289

Start: 4312304

End: 4313731

Strand: Direct

Name: arcD-2 [H]

Synonym: PST_3977

Alternate gene names: 146284289

Gene position: 4312304-4313731 (Clockwise)

Preceding gene: 146284287

Following gene: 146284290

Centisome position: 94.41

GC content: 64.29

Gene sequence:

>1428_bases
ATGGCCACGACCTCGAAGCAACTGAAACTCAGCGCGCTGGTGGCGCTGGTGATGGGTTCGATGATAGGCGGCGGAATCTT
TTCCCTGCCGCAGAACATGGCGGCCAGTGCCAGCGCCGGCGCCATCCTGATCGGCTGGGCAATCACTGCCGTGGGCATGC
TGACTCTGGCCTTCGTGTTCCAGAGCCTGGCCAACCGCAAGCCGGAACTCGACGCCGGTGTCTACGCCTATGCCAAGGCC
GGTTTCGGCGACTACATGGGCTTCTCCTCCGCATGGGGCTACTGGATCAGCGCCTGGATCGGCAACGTCAGCTACTTCGT
GTTGCTGTTCAGCACCCTCGGCTACTTCGTACCGATGTTCGGCGAGGGCAACACCCTGCCGGCGGTGATCGGCGCCTCGC
TGGTGCTCTGGGGCGTGCATTTCCTCGTTCTGCGCGGTATCCGCGAGGCGGCGTTCGTCAACCTGGTCACCACCATCGCC
AAGATCGTGCCGTTGATCCTGTTCATCGTGATCACCGCGGTGGCCTTCCGCCTGGACGTGTTCACTGCCGACTTCTGGGG
CCGTGGCAACCCGGAGCTGGGCAGCGTGATGCAGCAGGTGCGCAACATGATGCTGGTGACGGTGTGGGTGTTCATCGGTA
TCGAGGGCGCCAACGTGTTCTCGGCGCGCGCCGAGCGCCGTAGCGACGTCGGGCGCGCCACGGTCATCGGCTTCTATAGC
GTGCTCGCGCTGCTGGTGCTGGTGAACATCCTGTCGATGGGCATCATGAGTCAGGCCGAGCTGGCGGGCCTGAAGAACCC
TTCCATGGCGGGCGTGCTGGAGCAGGTGGTCGGTCGCTGGGGCGCGGTGCTGATCAGCGTCGGCCTGGTGGTTTCGCTGG
CCGGTGCCCTGTTGTCCTGGACCCTTCTGTGTGCCGAGATTCTCTTCGCCGCCGCCCGTGACCACACCATGCCGAGCTTC
CTGCGCAAGGAAAATGCCCGCCACGTTCCGGTCAATGCGCTGTGGCTGTCCAACGGGCTGATCCAGCTGTTCCTGATCAT
CACCCTGTTCAACGCCTCCACCTATCTCAGCCTGCTCTACCTCGCCACCTCGATGATCCTGGTGCCGTACTTCTGGTCGG
CGGCCTATGCGTTGCTGCTCGGGGTTCGCGGCGAGGGATACGCGAACGCCGCGGGTGAACGGCGCAAGGACACGCTGATC
GCCGCCGTCGCTACGCTATATGCCGTGTGGCTGGTCTATGCCGGTGGCATCCAGTATCTGCTGTTGTCGGCGCTGCTCTA
TGCGCCGGGGGCACTGTTCTTCGCCAAGGCCAAGCGCGAACTGGGGCAGCCGGTATTCAGCGGCGTCGAGAAGCTGATCT
TCGCCGCCGTGCTCATCGGGGCGGCGATCGCGGCCTACGGCCTCTACGACGGTTTCCTGTCCCTCTGA

Upstream 100 bases:

>100_bases
CACCATCACTCCCACACTTTCTTGACGTCTGTCATGACCGCAACGCACTGGCAGGCATTCAATGGTCCCGCTACGCACGG
TCTTGAAAGGAGACAGGGTA

Downstream 100 bases:

>100_bases
CCGGCGCCCCGGCGCCCTCTCTCGCCAAGGCCACAAGCGACGGCGAGCCACTCTGCACCTACCGGTGCAATGACTGACGG
AGGCAAATGCCATGACTCAG

Product: arginine/ornithine antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 475; Mature: 474

Protein sequence:

>475_residues
MATTSKQLKLSALVALVMGSMIGGGIFSLPQNMAASASAGAILIGWAITAVGMLTLAFVFQSLANRKPELDAGVYAYAKA
GFGDYMGFSSAWGYWISAWIGNVSYFVLLFSTLGYFVPMFGEGNTLPAVIGASLVLWGVHFLVLRGIREAAFVNLVTTIA
KIVPLILFIVITAVAFRLDVFTADFWGRGNPELGSVMQQVRNMMLVTVWVFIGIEGANVFSARAERRSDVGRATVIGFYS
VLALLVLVNILSMGIMSQAELAGLKNPSMAGVLEQVVGRWGAVLISVGLVVSLAGALLSWTLLCAEILFAAARDHTMPSF
LRKENARHVPVNALWLSNGLIQLFLIITLFNASTYLSLLYLATSMILVPYFWSAAYALLLGVRGEGYANAAGERRKDTLI
AAVATLYAVWLVYAGGIQYLLLSALLYAPGALFFAKAKRELGQPVFSGVEKLIFAAVLIGAAIAAYGLYDGFLSL

Sequences:

>Translated_475_residues
MATTSKQLKLSALVALVMGSMIGGGIFSLPQNMAASASAGAILIGWAITAVGMLTLAFVFQSLANRKPELDAGVYAYAKA
GFGDYMGFSSAWGYWISAWIGNVSYFVLLFSTLGYFVPMFGEGNTLPAVIGASLVLWGVHFLVLRGIREAAFVNLVTTIA
KIVPLILFIVITAVAFRLDVFTADFWGRGNPELGSVMQQVRNMMLVTVWVFIGIEGANVFSARAERRSDVGRATVIGFYS
VLALLVLVNILSMGIMSQAELAGLKNPSMAGVLEQVVGRWGAVLISVGLVVSLAGALLSWTLLCAEILFAAARDHTMPSF
LRKENARHVPVNALWLSNGLIQLFLIITLFNASTYLSLLYLATSMILVPYFWSAAYALLLGVRGEGYANAAGERRKDTLI
AAVATLYAVWLVYAGGIQYLLLSALLYAPGALFFAKAKRELGQPVFSGVEKLIFAAVLIGAAIAAYGLYDGFLSL
>Mature_474_residues
ATTSKQLKLSALVALVMGSMIGGGIFSLPQNMAASASAGAILIGWAITAVGMLTLAFVFQSLANRKPELDAGVYAYAKAG
FGDYMGFSSAWGYWISAWIGNVSYFVLLFSTLGYFVPMFGEGNTLPAVIGASLVLWGVHFLVLRGIREAAFVNLVTTIAK
IVPLILFIVITAVAFRLDVFTADFWGRGNPELGSVMQQVRNMMLVTVWVFIGIEGANVFSARAERRSDVGRATVIGFYSV
LALLVLVNILSMGIMSQAELAGLKNPSMAGVLEQVVGRWGAVLISVGLVVSLAGALLSWTLLCAEILFAAARDHTMPSFL
RKENARHVPVNALWLSNGLIQLFLIITLFNASTYLSLLYLATSMILVPYFWSAAYALLLGVRGEGYANAAGERRKDTLIA
AVATLYAVWLVYAGGIQYLLLSALLYAPGALFFAKAKRELGQPVFSGVEKLIFAAVLIGAAIAAYGLYDGFLSL

Specific function: Catalyzes an electroneutral exchange between arginine and ornithine to allow high-efficiency energy conversion in the arginine deiminase pathway [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI1787890, Length=468, Percent_Identity=45.7264957264957, Blast_Score=403, Evalue=1e-113,
Organism=Escherichia coli, GI2367353, Length=422, Percent_Identity=27.2511848341232, Blast_Score=132, Evalue=7e-32,
Organism=Escherichia coli, GI1790575, Length=387, Percent_Identity=27.1317829457364, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786908, Length=434, Percent_Identity=25.1152073732719, Blast_Score=87, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004754
- InterPro:   IPR022461 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 50872; Mature: 50741

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATTSKQLKLSALVALVMGSMIGGGIFSLPQNMAASASAGAILIGWAITAVGMLTLAFVF
CCCCHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
QSLANRKPELDAGVYAYAKAGFGDYMGFSSAWGYWISAWIGNVSYFVLLFSTLGYFVPMF
HHHHCCCCCCCCCHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GEGNTLPAVIGASLVLWGVHFLVLRGIREAAFVNLVTTIAKIVPLILFIVITAVAFRLDV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FTADFWGRGNPELGSVMQQVRNMMLVTVWVFIGIEGANVFSARAERRSDVGRATVIGFYS
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHH
VLALLVLVNILSMGIMSQAELAGLKNPSMAGVLEQVVGRWGAVLISVGLVVSLAGALLSW
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLLCAEILFAAARDHTMPSFLRKENARHVPVNALWLSNGLIQLFLIITLFNASTYLSLLY
HHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LATSMILVPYFWSAAYALLLGVRGEGYANAAGERRKDTLIAAVATLYAVWLVYAGGIQYL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHH
LLSALLYAPGALFFAKAKRELGQPVFSGVEKLIFAAVLIGAAIAAYGLYDGFLSL
HHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ATTSKQLKLSALVALVMGSMIGGGIFSLPQNMAASASAGAILIGWAITAVGMLTLAFVF
CCCHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH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HHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2158926; 10984043; 1311296 [H]