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The map label for this gene is yggW [H]

Identifier: 146284286

GI number: 146284286

Start: 4310235

End: 4311413

Strand: Direct

Name: yggW [H]

Synonym: PST_3974

Alternate gene names: 146284286

Gene position: 4310235-4311413 (Clockwise)

Preceding gene: 146284285

Following gene: 146284287

Centisome position: 94.37

GC content: 67.09

Gene sequence:

>1179_bases
ATGATCGCCGCAAGCCCCGCGCCGGCAACCGGCCAGGGCCGCTTCGAACTGCCGCCTCTGGCGGCGTACGTCCATATCCC
CTGGTGCGTGCGCAAGTGCCCGTACTGTGACTTCAACTCCCACACGGCCGGCCCTGCGCTGCCGGAAGAGGCCTATGTGG
CCGCGCTGCTGGCGGATCTGCGGGCCGACCTCGAGCACGTCCAGGGCCGCCGGCTGAGCTCGATCTTCTTCGGTGGCGGC
ACGCCAAGCCTGTTCTCCGCCCGGGCACTGGCCGCCATCGTCGAGGGCCTGGAGCATCTGGTCGGGTTCGCCGACGGCAT
CGAGATCACCCTCGAAGCCAACCCCGGGACCTTCGAGCAGGCCAAGTTCCGCGATTACCGCCAGCTCGGCATCAATCGGT
TGTCCATCGGCGTGCAGAGTTTCCAGGCCGCCAAGCTCAAGGCACTCGGGCGCATCCACGACGGCGACGAAGCCATCCGC
GCAGCGGACATGGCCCGTGCCGCAGGCTTCGAAAACTTCAACCTCGACCTCATGCATGGCCTGCCGGACCAGAGCCTGGA
GGATGCGCTGAGCGATCTGCGCACCGCCATCGCCCAGCAGCCGACGCACCTGTCCTGGTACCAGCTGACCCTGGAACCGA
ACACCCTGTTCTGGAGCCAGCCACCGCAGCTGCCGGAAGACGACATCCTCTGGGACATCCAGGAAGCCGGCCAGGCACTG
CTCGGCGAGCACGGCTATCGCCAGTACGAGACCTCCGCCTATGCCCAGCCGGGCCGACAGGCGAGGCACAACCTGAACTA
CTGGACCTTCGGCGACTTCCTCGGCATCGGTGCCGGCGCCCATGCCAAGCTCAGCCATGCCGACGGCCGCATCCTGCGCA
GCTGGAAGACCCGCCTGCCGAAGGACTACCTCGATCCGGCCAAGGCCTTCCGCGCAGGCGAGAAGCAGCTGACCGCGGAC
GAGCTGCCCTTCGAATTCCTGATGAATGTGCTGCGCCTCACCGACGGCGTGCCGGCCGTGCTGTTCACTCAACGCACAGG
GCTGGCGCTGGATGCGATCGCCAAGCCACGGCGCGACGCCGAGGCTCGGGGTCTGCTGTCCAACGATCCCGACCGGCTGG
TGGCGACGCCCAAGGGCCAGCTGTTTCTCAACGACCTGCTACAGAGCTTCCTGCCTTAA

Upstream 100 bases:

>100_bases
CGGAGTGCGACTGCTCCAGCGCCGAGCTGCCCGCCGCGCAGAAGAACCAGCTCAGCCACCGCGCACGCGCCATGGCCCTG
CTCAAGCAGCGGCTGGGGAT

Downstream 100 bases:

>100_bases
GGACCCTGCATGGATTTGCTACTCGACCTGATCGTCACGCTGTCGCGCTGGAGCCGCAGTCACCTGTCCGATATCTCCCT
GGCGCTGATGGCAACGCTCT

Product: coproporphyrinogen III oxidase

Products: Protoporphyrinogen IX; CO2; H2O

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MIAASPAPATGQGRFELPPLAAYVHIPWCVRKCPYCDFNSHTAGPALPEEAYVAALLADLRADLEHVQGRRLSSIFFGGG
TPSLFSARALAAIVEGLEHLVGFADGIEITLEANPGTFEQAKFRDYRQLGINRLSIGVQSFQAAKLKALGRIHDGDEAIR
AADMARAAGFENFNLDLMHGLPDQSLEDALSDLRTAIAQQPTHLSWYQLTLEPNTLFWSQPPQLPEDDILWDIQEAGQAL
LGEHGYRQYETSAYAQPGRQARHNLNYWTFGDFLGIGAGAHAKLSHADGRILRSWKTRLPKDYLDPAKAFRAGEKQLTAD
ELPFEFLMNVLRLTDGVPAVLFTQRTGLALDAIAKPRRDAEARGLLSNDPDRLVATPKGQLFLNDLLQSFLP

Sequences:

>Translated_392_residues
MIAASPAPATGQGRFELPPLAAYVHIPWCVRKCPYCDFNSHTAGPALPEEAYVAALLADLRADLEHVQGRRLSSIFFGGG
TPSLFSARALAAIVEGLEHLVGFADGIEITLEANPGTFEQAKFRDYRQLGINRLSIGVQSFQAAKLKALGRIHDGDEAIR
AADMARAAGFENFNLDLMHGLPDQSLEDALSDLRTAIAQQPTHLSWYQLTLEPNTLFWSQPPQLPEDDILWDIQEAGQAL
LGEHGYRQYETSAYAQPGRQARHNLNYWTFGDFLGIGAGAHAKLSHADGRILRSWKTRLPKDYLDPAKAFRAGEKQLTAD
ELPFEFLMNVLRLTDGVPAVLFTQRTGLALDAIAKPRRDAEARGLLSNDPDRLVATPKGQLFLNDLLQSFLP
>Mature_392_residues
MIAASPAPATGQGRFELPPLAAYVHIPWCVRKCPYCDFNSHTAGPALPEEAYVAALLADLRADLEHVQGRRLSSIFFGGG
TPSLFSARALAAIVEGLEHLVGFADGIEITLEANPGTFEQAKFRDYRQLGINRLSIGVQSFQAAKLKALGRIHDGDEAIR
AADMARAAGFENFNLDLMHGLPDQSLEDALSDLRTAIAQQPTHLSWYQLTLEPNTLFWSQPPQLPEDDILWDIQEAGQAL
LGEHGYRQYETSAYAQPGRQARHNLNYWTFGDFLGIGAGAHAKLSHADGRILRSWKTRLPKDYLDPAKAFRAGEKQLTAD
ELPFEFLMNVLRLTDGVPAVLFTQRTGLALDAIAKPRRDAEARGLLSNDPDRLVATPKGQLFLNDLLQSFLP

Specific function: Unknown

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=269, Percent_Identity=37.1747211895911, Blast_Score=177, Evalue=2e-44,
Organism=Escherichia coli, GI1789325, Length=376, Percent_Identity=54.7872340425532, Blast_Score=416, Evalue=1e-117,
Organism=Escherichia coli, GI87082341, Length=284, Percent_Identity=28.8732394366197, Blast_Score=108, Evalue=8e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: 1.3.3.3

Molecular weight: Translated: 43164; Mature: 43164

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAASPAPATGQGRFELPPLAAYVHIPWCVRKCPYCDFNSHTAGPALPEEAYVAALLADL
CCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHH
RADLEHVQGRRLSSIFFGGGTPSLFSARALAAIVEGLEHLVGFADGIEITLEANPGTFEQ
HHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHH
AKFRDYRQLGINRLSIGVQSFQAAKLKALGRIHDGDEAIRAADMARAAGFENFNLDLMHG
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCHHCCC
LPDQSLEDALSDLRTAIAQQPTHLSWYQLTLEPNTLFWSQPPQLPEDDILWDIQEAGQAL
CCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEEECCCCCCCCCCCEEEHHHHHHHH
LGEHGYRQYETSAYAQPGRQARHNLNYWTFGDFLGIGAGAHAKLSHADGRILRSWKTRLP
HHHCCCHHHHHHHHCCCCHHHHHCCCCEECHHHHHCCCCCCCEECCCCHHHHHHHHHHCC
KDYLDPAKAFRAGEKQLTADELPFEFLMNVLRLTDGVPAVLFTQRTGLALDAIAKPRRDA
HHHCCHHHHHHCCCHHCCHHCCCHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHCCCCCH
EARGLLSNDPDRLVATPKGQLFLNDLLQSFLP
HHCCCCCCCCCCEEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MIAASPAPATGQGRFELPPLAAYVHIPWCVRKCPYCDFNSHTAGPALPEEAYVAALLADL
CCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHH
RADLEHVQGRRLSSIFFGGGTPSLFSARALAAIVEGLEHLVGFADGIEITLEANPGTFEQ
HHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHH
AKFRDYRQLGINRLSIGVQSFQAAKLKALGRIHDGDEAIRAADMARAAGFENFNLDLMHG
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCHHCCC
LPDQSLEDALSDLRTAIAQQPTHLSWYQLTLEPNTLFWSQPPQLPEDDILWDIQEAGQAL
CCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEEECCCCCCCCCCCEEEHHHHHHHH
LGEHGYRQYETSAYAQPGRQARHNLNYWTFGDFLGIGAGAHAKLSHADGRILRSWKTRLP
HHHCCCHHHHHHHHCCCCHHHHHCCCCEECHHHHHCCCCCCCEECCCCHHHHHHHHHHCC
KDYLDPAKAFRAGEKQLTADELPFEFLMNVLRLTDGVPAVLFTQRTGLALDAIAKPRRDA
HHHCCHHHHHHCCCHHCCHHCCCHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHCCCCCH
EARGLLSNDPDRLVATPKGQLFLNDLLQSFLP
HHCCCCCCCCCCEEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coproporphyrinogen III; O2; H+

Specific reaction: coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]