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The map label for this gene is yggV [C]

Identifier: 146284285

GI number: 146284285

Start: 4309645

End: 4310238

Strand: Direct

Name: yggV [C]

Synonym: PST_3973

Alternate gene names: 146284285

Gene position: 4309645-4310238 (Clockwise)

Preceding gene: 146284284

Following gene: 146284286

Centisome position: 94.36

GC content: 69.02

Gene sequence:

>594_bases
ATGATGCCTTTTTCCGAACTGGTGCTGGCCAGTCACAACGCCGGCAAACTCAAGGAACTCCAGGCCATGCTCGGCGACGC
CGTGCGCGTCCGCTCGGTGGCCGAGTTCAGCACCGTGGAGCCGGAAGAAACCGGCCTGTCCTTCATCGAGAACGCCATTC
TCAAGGCGCGCAATGCGGCACGGATCTCCGGCCTGCCGGCCCTGGCCGATGACTCGGGCCTGGCGGTCGACGCCCTGGGC
GGCGCACCGGGTATCTACTCGGCGCGCTACGCCGATGGCCAGGGCGACGCAGCCAACAACGCCAAGCTGCTGCAGGTGCT
GCGCGACGTGCCGGACGCCGAGCGCGGCGCGCAGTTCGTCTGTGCGCTGGCCCTGGTGCGGCACGCCGACGATCCGCTGC
CGATCATCTGCGAAGGCCTCTGGCATGGGCGCATCCTGCATGCGCCGCGCGGCGAGCACGGCTTCGGCTACGACCCGCTG
TTCTGGGTACCGGAGTGCGACTGCTCCAGCGCCGAGCTGCCCGCCGCGCAGAAGAACCAGCTCAGCCACCGCGCACGCGC
CATGGCCCTGCTCAAGCAGCGGCTGGGGATATGA

Upstream 100 bases:

>100_bases
CCTTCGACTCCCAGGAAACCCTGCGCTTCCGCCTCACCGTGCAGCCGACCGGCGCGCAGCCGTTCAGTTTCGAGTTCAAC
CAGGAATTCTTCCCCGACCG

Downstream 100 bases:

>100_bases
TCGCCGCAAGCCCCGCGCCGGCAACCGGCCAGGGCCGCTTCGAACTGCCGCCTCTGGCGGCGTACGTCCATATCCCCTGG
TGCGTGCGCAAGTGCCCGTA

Product: putative deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MMPFSELVLASHNAGKLKELQAMLGDAVRVRSVAEFSTVEPEETGLSFIENAILKARNAARISGLPALADDSGLAVDALG
GAPGIYSARYADGQGDAANNAKLLQVLRDVPDAERGAQFVCALALVRHADDPLPIICEGLWHGRILHAPRGEHGFGYDPL
FWVPECDCSSAELPAAQKNQLSHRARAMALLKQRLGI

Sequences:

>Translated_197_residues
MMPFSELVLASHNAGKLKELQAMLGDAVRVRSVAEFSTVEPEETGLSFIENAILKARNAARISGLPALADDSGLAVDALG
GAPGIYSARYADGQGDAANNAKLLQVLRDVPDAERGAQFVCALALVRHADDPLPIICEGLWHGRILHAPRGEHGFGYDPL
FWVPECDCSSAELPAAQKNQLSHRARAMALLKQRLGI
>Mature_197_residues
MMPFSELVLASHNAGKLKELQAMLGDAVRVRSVAEFSTVEPEETGLSFIENAILKARNAARISGLPALADDSGLAVDALG
GAPGIYSARYADGQGDAANNAKLLQVLRDVPDAERGAQFVCALALVRHADDPLPIICEGLWHGRILHAPRGEHGFGYDPL
FWVPECDCSSAELPAAQKNQLSHRARAMALLKQRLGI

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Homo sapiens, GI15626999, Length=193, Percent_Identity=34.1968911917098, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI31657144, Length=175, Percent_Identity=34.2857142857143, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1789324, Length=190, Percent_Identity=51.0526315789474, Blast_Score=197, Evalue=3e-52,
Organism=Drosophila melanogaster, GI19920712, Length=189, Percent_Identity=34.3915343915344, Blast_Score=89, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 21061; Mature: 21061

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMPFSELVLASHNAGKLKELQAMLGDAVRVRSVAEFSTVEPEETGLSFIENAILKARNAA
CCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCH
RISGLPALADDSGLAVDALGGAPGIYSARYADGQGDAANNAKLLQVLRDVPDAERGAQFV
HHCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHH
CALALVRHADDPLPIICEGLWHGRILHAPRGEHGFGYDPLFWVPECDCSSAELPAAQKNQ
HHHHHHHHCCCCCCEEECCCCCCEEEECCCCCCCCCCCCEEECCCCCCCCCCCCCHHHHH
LSHRARAMALLKQRLGI
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMPFSELVLASHNAGKLKELQAMLGDAVRVRSVAEFSTVEPEETGLSFIENAILKARNAA
CCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCH
RISGLPALADDSGLAVDALGGAPGIYSARYADGQGDAANNAKLLQVLRDVPDAERGAQFV
HHCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHH
CALALVRHADDPLPIICEGLWHGRILHAPRGEHGFGYDPLFWVPECDCSSAELPAAQKNQ
HHHHHHHHCCCCCCEEECCCCCCEEEECCCCCCCCCCCCEEECCCCCCCCCCCCCHHHHH
LSHRARAMALLKQRLGI
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12928499 [H]