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The map label for this gene is glcB [H]

Identifier: 146284210

GI number: 146284210

Start: 4225614

End: 4227794

Strand: Direct

Name: glcB [H]

Synonym: PST_3898

Alternate gene names: 146284210

Gene position: 4225614-4227794 (Clockwise)

Preceding gene: 146284208

Following gene: 146284211

Centisome position: 92.52

GC content: 64.88

Gene sequence:

>2181_bases
ATGACTGAGCGCGTTCAAGTCGGTGGCCTGCAGGTCGCCAAAGTCCTGTACGACTTCGTGAACAACGAGGCGATTCCCGG
TACCGGCGTCGATGCCGCCGCCTTCTGGGCTGGCGCCGACAGCGTGATCCACGACCTGGCGCCGAAGAACCGCGCCCTGC
TGGCCAAGCGCGACGAGCTGCAGGCCAAGATCGACGCCTGGCACCAGGCCCGCGCCGGCCAGGCCCATGACGCCGTGGCG
TACAAGGCCTTCCTTCAGGAAATCGGCTACCTGCTGCCGGAAGCCGAAGACTTCCAGGCCACCACCGAGAACGTCGACGA
AGAAATCGCCCGCATGGCCGGCCCGCAGCTGGTGGTGCCGATCATGAACGCGCGCTTCGCCCTGAACGCCGCCAACGCCC
GCTGGGGCTCGCTGTATGACGCGCTCTACGGCACCGACGCCATCTCCGAAGCGGACGGCGCCACCAAGGGGCCGGGCTAC
AACGAGATCCGCGGCAACAAGGTCATCGCCTATGCGCGCAATTTCCTCAACGAAGCTGCACCGCTGGAAACCGGCTCGCA
CGTCGATTCCACCGGCTATCGCATCGAAGGCGGCAAGCTGGTCGTTTCGCTGAAGGATGGCAGCACCACCGGCCTGAAGA
ACCCGGCCCAGCTGCAGGGCTTCCAGGGCGACGCCAGCGCACCGATCGCCGTGCTGCTGAAGAACAACGGCATCCACTTC
GAGATCCAGATCGACCCGGCCAGCCCGATCGGCCAGACCGATGCCGCCGGCGTGAAGGACATCCTGATGGAATCGGCACT
GACCACCATCATGGACTGCGAAGACTCCATCGCCGCCGTCGACGCCGACGACAAGACCATCGTCTACCGCAACTGGCTCG
GCCTGATGAAGGGCGATCTGGTCGAGGAGCTGGACAAGGGCGGCAAGCGCATCACCCGCGCCATGAACCCGGACCGCGTC
TACACCAAGGCCGACGGCAACGGCGAGCTGACCCTGCACGGACGCTCGCTGCTGTTCATCCGCAACGTCGGTCACCTGAT
GACCAACGACGCCATCCTCGACAAGGCAGGCAACGAAGTGCCGGAAGGCATCATGGACGGCCTGTTCACCAGCCTGATCG
CCATCCACAACCTCAAGGGCAACACCACCCGCGCCAACAGCCGCACCGGCTCGATGTACATCGTCAAGCCGAAGATGCAC
GGCCCGGAAGAAGTCGCCTTCGCCACCGAGCTGTTCGGCCGCGTCGAGGACGTTCTCGGCCTGCCGCGCAACACCCTCAA
GGTCGGCATCATGGATGAGGAGCGTCGTACCACGATCAACCTCAAGGCCTGCATCAAGGAAGCGCGCGAGCGCGTGGTGT
TCATCAACACCGGCTTCCTCGACCGCACCGGCGACGAAATCCATACCTCCATGGAAGCCGGCCCGATGGTGCGCAAGGCG
GCCATGAAGTCCGAGAAATGGATCAGCGCCTACGAGAACAACAACGTGGACGTGGGCCTGGCCTGCGGCCTGCAGGGCAA
GGCGCAGATCGGCAAGGGCATGTGGGCCATGCCTGACCTGATGGCCGCCATGCTCGAGCAGAAGGTCGGCCATCCGCTGG
CCGGCGCCAACACCGCGTGGGTACCGTCGCCGACCGCAGCCACCCTGCACGCGATGCACTACCACAAGATCGACGTGCAG
GCGCGCCAGGCCGAACTGGCCAAGCGCGAGAAGGCTTCGATCGATGACATCCTCACCATCCCGCTGGCACAGAACACCAA
CTGGAGCGAGGAAGAGAAGCGCAACGAGCTGGACAACAACTCGCAGGGCATCCTCGGCTACATGGTGCGCTGGGTCGAAC
AGGGCGTTGGTTGCTCCAAGGTGCCGGACATCAACGACATCGCGCTGATGGAAGACCGTGCCACCCTGCGCATCTCCAGC
CAGCACGTGGCCAACTGGATGCGCCACGGCGTGGTAACCAAGGACCAGGTGATCGAGAGCCTCAAGCGCATGGCCCCGGT
GGTCGACCGCCAGAACCAGGGTGACCCGCTGTACCGCCCGATGGCGCCTGACTTCGACAACAGCGTGGCCTTCCAGGCTG
CGCTGGAGCTGGTCCTCGAAGGCACCAAGCAGCCCAACGGCTACACCGAGCCGGTCCTGCACCGTCGCCGCCGCGAGTTC
AAGGCCAAGAACGGCCTGTAA

Upstream 100 bases:

>100_bases
GCGGACTGATTTTCCCCGACGCTTCATGTAGTATCCGGCGACCTCGGACTACAAAAAGCGAAACCGTCCGGCGAATTAGA
AGAACCAAGTGAGGCGAGTA

Downstream 100 bases:

>100_bases
CCGCCAGCCGCGACAGAAGAACCGCCCTTCGGGGCGGTTTTTTTATGCCTGCGCCCTCGCAACAGCCCGAAACATCGGGC
TGACTCTGATCAGCTTCCGC

Product: malate synthase G

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 726; Mature: 725

Protein sequence:

>726_residues
MTERVQVGGLQVAKVLYDFVNNEAIPGTGVDAAAFWAGADSVIHDLAPKNRALLAKRDELQAKIDAWHQARAGQAHDAVA
YKAFLQEIGYLLPEAEDFQATTENVDEEIARMAGPQLVVPIMNARFALNAANARWGSLYDALYGTDAISEADGATKGPGY
NEIRGNKVIAYARNFLNEAAPLETGSHVDSTGYRIEGGKLVVSLKDGSTTGLKNPAQLQGFQGDASAPIAVLLKNNGIHF
EIQIDPASPIGQTDAAGVKDILMESALTTIMDCEDSIAAVDADDKTIVYRNWLGLMKGDLVEELDKGGKRITRAMNPDRV
YTKADGNGELTLHGRSLLFIRNVGHLMTNDAILDKAGNEVPEGIMDGLFTSLIAIHNLKGNTTRANSRTGSMYIVKPKMH
GPEEVAFATELFGRVEDVLGLPRNTLKVGIMDEERRTTINLKACIKEARERVVFINTGFLDRTGDEIHTSMEAGPMVRKA
AMKSEKWISAYENNNVDVGLACGLQGKAQIGKGMWAMPDLMAAMLEQKVGHPLAGANTAWVPSPTAATLHAMHYHKIDVQ
ARQAELAKREKASIDDILTIPLAQNTNWSEEEKRNELDNNSQGILGYMVRWVEQGVGCSKVPDINDIALMEDRATLRISS
QHVANWMRHGVVTKDQVIESLKRMAPVVDRQNQGDPLYRPMAPDFDNSVAFQAALELVLEGTKQPNGYTEPVLHRRRREF
KAKNGL

Sequences:

>Translated_726_residues
MTERVQVGGLQVAKVLYDFVNNEAIPGTGVDAAAFWAGADSVIHDLAPKNRALLAKRDELQAKIDAWHQARAGQAHDAVA
YKAFLQEIGYLLPEAEDFQATTENVDEEIARMAGPQLVVPIMNARFALNAANARWGSLYDALYGTDAISEADGATKGPGY
NEIRGNKVIAYARNFLNEAAPLETGSHVDSTGYRIEGGKLVVSLKDGSTTGLKNPAQLQGFQGDASAPIAVLLKNNGIHF
EIQIDPASPIGQTDAAGVKDILMESALTTIMDCEDSIAAVDADDKTIVYRNWLGLMKGDLVEELDKGGKRITRAMNPDRV
YTKADGNGELTLHGRSLLFIRNVGHLMTNDAILDKAGNEVPEGIMDGLFTSLIAIHNLKGNTTRANSRTGSMYIVKPKMH
GPEEVAFATELFGRVEDVLGLPRNTLKVGIMDEERRTTINLKACIKEARERVVFINTGFLDRTGDEIHTSMEAGPMVRKA
AMKSEKWISAYENNNVDVGLACGLQGKAQIGKGMWAMPDLMAAMLEQKVGHPLAGANTAWVPSPTAATLHAMHYHKIDVQ
ARQAELAKREKASIDDILTIPLAQNTNWSEEEKRNELDNNSQGILGYMVRWVEQGVGCSKVPDINDIALMEDRATLRISS
QHVANWMRHGVVTKDQVIESLKRMAPVVDRQNQGDPLYRPMAPDFDNSVAFQAALELVLEGTKQPNGYTEPVLHRRRREF
KAKNGL
>Mature_725_residues
TERVQVGGLQVAKVLYDFVNNEAIPGTGVDAAAFWAGADSVIHDLAPKNRALLAKRDELQAKIDAWHQARAGQAHDAVAY
KAFLQEIGYLLPEAEDFQATTENVDEEIARMAGPQLVVPIMNARFALNAANARWGSLYDALYGTDAISEADGATKGPGYN
EIRGNKVIAYARNFLNEAAPLETGSHVDSTGYRIEGGKLVVSLKDGSTTGLKNPAQLQGFQGDASAPIAVLLKNNGIHFE
IQIDPASPIGQTDAAGVKDILMESALTTIMDCEDSIAAVDADDKTIVYRNWLGLMKGDLVEELDKGGKRITRAMNPDRVY
TKADGNGELTLHGRSLLFIRNVGHLMTNDAILDKAGNEVPEGIMDGLFTSLIAIHNLKGNTTRANSRTGSMYIVKPKMHG
PEEVAFATELFGRVEDVLGLPRNTLKVGIMDEERRTTINLKACIKEARERVVFINTGFLDRTGDEIHTSMEAGPMVRKAA
MKSEKWISAYENNNVDVGLACGLQGKAQIGKGMWAMPDLMAAMLEQKVGHPLAGANTAWVPSPTAATLHAMHYHKIDVQA
RQAELAKREKASIDDILTIPLAQNTNWSEEEKRNELDNNSQGILGYMVRWVEQGVGCSKVPDINDIALMEDRATLRISSQ
HVANWMRHGVVTKDQVIESLKRMAPVVDRQNQGDPLYRPMAPDFDNSVAFQAALELVLEGTKQPNGYTEPVLHRRRREFK
AKNGL

Specific function: Accounts For Almost The Entire Malate-Synthesizing Activity In Cells Metabolizing Glyoxylate. [C]

COG id: COG2225

COG function: function code C; Malate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the malate synthase family. GlcB subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789348, Length=722, Percent_Identity=60.6648199445983, Blast_Score=922, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17561814, Length=296, Percent_Identity=24.3243243243243, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011076
- InterPro:   IPR001465
- InterPro:   IPR006253 [H]

Pfam domain/function: PF01274 Malate_synthase [H]

EC number: =2.3.3.9 [H]

Molecular weight: Translated: 79409; Mature: 79278

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTERVQVGGLQVAKVLYDFVNNEAIPGTGVDAAAFWAGADSVIHDLAPKNRALLAKRDEL
CCCCEECCCHHHHHHHHHHHCCCCCCCCCCCHHHHHCCHHHHHHHCCCCCCEEEEHHHHH
QAKIDAWHQARAGQAHDAVAYKAFLQEIGYLLPEAEDFQATTENVDEEIARMAGPQLVVP
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEE
IMNARFALNAANARWGSLYDALYGTDAISEADGATKGPGYNEIRGNKVIAYARNFLNEAA
ECCCEEEEECCCCCHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCEEHHHHHHHHHHCC
PLETGSHVDSTGYRIEGGKLVVSLKDGSTTGLKNPAQLQGFQGDASAPIAVLLKNNGIHF
CCCCCCCCCCCCEEEECCEEEEEECCCCCCCCCCCHHHCCCCCCCCCCEEEEEECCCEEE
EIQIDPASPIGQTDAAGVKDILMESALTTIMDCEDSIAAVDADDKTIVYRNWLGLMKGDL
EEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEHHHHHHHHHHH
VEELDKGGKRITRAMNPDRVYTKADGNGELTLHGRSLLFIRNVGHLMTNDAILDKAGNEV
HHHHHCCHHHHHHCCCCCCEEEECCCCCEEEEECCEEEEEECCCHHHHCCHHHHCCCCCC
PEGIMDGLFTSLIAIHNLKGNTTRANSRTGSMYIVKPKMHGPEEVAFATELFGRVEDVLG
HHHHHHHHHHHHHHHHCCCCCCEECCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHC
LPRNTLKVGIMDEERRTTINLKACIKEARERVVFINTGFLDRTGDEIHTSMEAGPMVRKA
CCCCCEEEEEEECCCCCEEHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHCHHHHHH
AMKSEKWISAYENNNVDVGLACGLQGKAQIGKGMWAMPDLMAAMLEQKVGHPLAGANTAW
HHHHHHHHHHHCCCCCEEEEEECCCCHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
VPSPTAATLHAMHYHKIDVQARQAELAKREKASIDDILTIPLAQNTNWSEEEKRNELDNN
CCCCCHHHHHHHHHEEECCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHCCCC
SQGILGYMVRWVEQGVGCSKVPDINDIALMEDRATLRISSQHVANWMRHGVVTKDQVIES
CCHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCEEEECHHHHHHHHHCCCCCHHHHHHH
LKRMAPVVDRQNQGDPLYRPMAPDFDNSVAFQAALELVLEGTKQPNGYTEPVLHRRRREF
HHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
KAKNGL
HHCCCC
>Mature Secondary Structure 
TERVQVGGLQVAKVLYDFVNNEAIPGTGVDAAAFWAGADSVIHDLAPKNRALLAKRDEL
CCCEECCCHHHHHHHHHHHCCCCCCCCCCCHHHHHCCHHHHHHHCCCCCCEEEEHHHHH
QAKIDAWHQARAGQAHDAVAYKAFLQEIGYLLPEAEDFQATTENVDEEIARMAGPQLVVP
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEE
IMNARFALNAANARWGSLYDALYGTDAISEADGATKGPGYNEIRGNKVIAYARNFLNEAA
ECCCEEEEECCCCCHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCEEHHHHHHHHHHCC
PLETGSHVDSTGYRIEGGKLVVSLKDGSTTGLKNPAQLQGFQGDASAPIAVLLKNNGIHF
CCCCCCCCCCCCEEEECCEEEEEECCCCCCCCCCCHHHCCCCCCCCCCEEEEEECCCEEE
EIQIDPASPIGQTDAAGVKDILMESALTTIMDCEDSIAAVDADDKTIVYRNWLGLMKGDL
EEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEHHHHHHHHHHH
VEELDKGGKRITRAMNPDRVYTKADGNGELTLHGRSLLFIRNVGHLMTNDAILDKAGNEV
HHHHHCCHHHHHHCCCCCCEEEECCCCCEEEEECCEEEEEECCCHHHHCCHHHHCCCCCC
PEGIMDGLFTSLIAIHNLKGNTTRANSRTGSMYIVKPKMHGPEEVAFATELFGRVEDVLG
HHHHHHHHHHHHHHHHCCCCCCEECCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHC
LPRNTLKVGIMDEERRTTINLKACIKEARERVVFINTGFLDRTGDEIHTSMEAGPMVRKA
CCCCCEEEEEEECCCCCEEHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHCHHHHHH
AMKSEKWISAYENNNVDVGLACGLQGKAQIGKGMWAMPDLMAAMLEQKVGHPLAGANTAW
HHHHHHHHHHHCCCCCEEEEEECCCCHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
VPSPTAATLHAMHYHKIDVQARQAELAKREKASIDDILTIPLAQNTNWSEEEKRNELDNN
CCCCCHHHHHHHHHEEECCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHCCCC
SQGILGYMVRWVEQGVGCSKVPDINDIALMEDRATLRISSQHVANWMRHGVVTKDQVIES
CCHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCEEEECHHHHHHHHHCCCCCHHHHHHH
LKRMAPVVDRQNQGDPLYRPMAPDFDNSVAFQAALELVLEGTKQPNGYTEPVLHRRRREF
HHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
KAKNGL
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA