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The map label for this gene is lnt [H]

Identifier: 146284077

GI number: 146284077

Start: 4072782

End: 4074335

Strand: Direct

Name: lnt [H]

Synonym: PST_3765

Alternate gene names: 146284077

Gene position: 4072782-4074335 (Clockwise)

Preceding gene: 146284076

Following gene: 146284080

Centisome position: 89.17

GC content: 66.86

Gene sequence:

>1554_bases
TTGCCCTTAGCCTGCGCCGCAATCCCCGCCCAAGGAAACCCCATGCACTGGTTCACCCGCCCCGGCTGGCCGGGCAATCT
GCTGGCGCTACTGGCCGGCACGCTGACCACGCTCTCTCTGGCCCCCTTCGACATCTGGCCGCTGGCCCTGTTATCGGTGG
CACTGCTCTACCTCGGCCTGCGCGAAACCGGGCCGAAACAGGCCGCGCGACGCGGCTGGTGCTACGGCTTCGGCCTGTTC
GCCTCGGGCGTCAGCTGGGTCTACGTCAGCATCCATGACTTCGGCGCGGCGTCGCCGCCATTGGCCGGGCTGCTGACGTT
CGGCTTTGTCGCCGGCCTGGCGCTGTTCTTCGCCCTGCTCGGCTGGCTCTGGGTGCGGCTGCTGCGCAATCGCCATTCGG
CGCTCGGTGACGCGCTGGCCTTCACCGCGCTCTGGCTGGCCTTCGACGCCCTGCGTGGCTGGCTGCTCACCGGCTTTCCC
TGGCTCTATATCGGCTACAGTCAGCTCGACGGCCCGCTATCCGGCCTGGCACCGGTGGGTGGCGTCTGGCTGCTGAGCTT
CGCCATCGCCCTGAGCGCCACCCTGCTCGTCGCGCTGCCGCGGCTGCGTGCCGACAAGCCGCGTCTGGCGGCTGGCATCC
TGTTGCTGATCGCCCCCTGGCTGACCGGACTGGCGCTCAAGGATCGCGCCTGGACCCAAGACAAGGGCGAGCCCTTGAGC
GTGGTTGCAGTGCAGGGCAACGTCGAGCAGAGCATGAAGTGGGACCCGAAGAAGCTCGAGATGCAGCTGCTGCTGTATCG
CGACATGACCTTTCGCAGCCGTCCGGCGGACCTGATCGTCTGGCCGGAAACCGCCGTGCCGATCCTCAAGGAACACGCCG
AAGGCTACCTTACAATGATGGCCGGCTTCGCCAAGCAGCGCGGATCGGCGCTCATCACCGGTGTGCCGGTGCGCCAGCCC
AACGCAGAGGGTGAGCTGCGCTACTACAACGGCCTGACCACCGCTGGCGAGGATGCCGGTACCTACCTCAAGCAGAAGCT
GGTGCCGTTCGGCGAGTATGTGCCGCTGCAGGAACTGTTGCGCGGGCTGATCGCCTTCTTCGACCTGCCGATGTCCGATT
TCGCCCGCGGCGAATCCGGCCAGCCGCTGCTACAGGCCAGAGGCCTGCAGATCGCACCCTATATCTGTTACGAAGTGGTC
TATCCGGAGTTCGCCGCGGGCCTCGCGGCGCAGAGCGACCTGCTGCTGACGGTGAGCAACGACGCCTGGTTCGGCCGCTC
CATCGGCCCACTGCAGCACCTGCAGATGGCGCAGATGCGCGCGCTGGAGGCCGGGCGCTGGATGATCCGCGCGACCAACA
ACGGCATCACCGTGCTTATCGACCCCTATGGGCGCATCACCGAGCAGATTCCGCAGTTCGAACAGGCCGTGCTGTATGGC
GAGGTCACGCCAATGCAGGGGCTTACGCCCTACCTGCGCTGGCGCTCCTGGCCGCTGATCGCGGTATGCGTGTTGCTGCT
CGGCTGGGCACTGGTCAGACGCAAGTCCGCATAG

Upstream 100 bases:

>100_bases
GTGCACATGCTGCGCCTGAGCCGCCTGGAAAGCGCTTGACCTGCAACTTGCCGCCCGCTTGCGGGCGGCAAGCGATCGGC
CAGCTTGCCGGATCGCCTCG

Downstream 100 bases:

>100_bases
GGACGCTCTGTGTCCCTGCGACTGGGAGAGAGCATTCCGCTCATTCGTTCGCCGAGCGATAAACCAGCGGGTACACCGCC
ATCCCCACCACTTCGTTGAG

Product: apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: ALP N-acyltransferase [H]

Number of amino acids: Translated: 517; Mature: 516

Protein sequence:

>517_residues
MPLACAAIPAQGNPMHWFTRPGWPGNLLALLAGTLTTLSLAPFDIWPLALLSVALLYLGLRETGPKQAARRGWCYGFGLF
ASGVSWVYVSIHDFGAASPPLAGLLTFGFVAGLALFFALLGWLWVRLLRNRHSALGDALAFTALWLAFDALRGWLLTGFP
WLYIGYSQLDGPLSGLAPVGGVWLLSFAIALSATLLVALPRLRADKPRLAAGILLLIAPWLTGLALKDRAWTQDKGEPLS
VVAVQGNVEQSMKWDPKKLEMQLLLYRDMTFRSRPADLIVWPETAVPILKEHAEGYLTMMAGFAKQRGSALITGVPVRQP
NAEGELRYYNGLTTAGEDAGTYLKQKLVPFGEYVPLQELLRGLIAFFDLPMSDFARGESGQPLLQARGLQIAPYICYEVV
YPEFAAGLAAQSDLLLTVSNDAWFGRSIGPLQHLQMAQMRALEAGRWMIRATNNGITVLIDPYGRITEQIPQFEQAVLYG
EVTPMQGLTPYLRWRSWPLIAVCVLLLGWALVRRKSA

Sequences:

>Translated_517_residues
MPLACAAIPAQGNPMHWFTRPGWPGNLLALLAGTLTTLSLAPFDIWPLALLSVALLYLGLRETGPKQAARRGWCYGFGLF
ASGVSWVYVSIHDFGAASPPLAGLLTFGFVAGLALFFALLGWLWVRLLRNRHSALGDALAFTALWLAFDALRGWLLTGFP
WLYIGYSQLDGPLSGLAPVGGVWLLSFAIALSATLLVALPRLRADKPRLAAGILLLIAPWLTGLALKDRAWTQDKGEPLS
VVAVQGNVEQSMKWDPKKLEMQLLLYRDMTFRSRPADLIVWPETAVPILKEHAEGYLTMMAGFAKQRGSALITGVPVRQP
NAEGELRYYNGLTTAGEDAGTYLKQKLVPFGEYVPLQELLRGLIAFFDLPMSDFARGESGQPLLQARGLQIAPYICYEVV
YPEFAAGLAAQSDLLLTVSNDAWFGRSIGPLQHLQMAQMRALEAGRWMIRATNNGITVLIDPYGRITEQIPQFEQAVLYG
EVTPMQGLTPYLRWRSWPLIAVCVLLLGWALVRRKSA
>Mature_516_residues
PLACAAIPAQGNPMHWFTRPGWPGNLLALLAGTLTTLSLAPFDIWPLALLSVALLYLGLRETGPKQAARRGWCYGFGLFA
SGVSWVYVSIHDFGAASPPLAGLLTFGFVAGLALFFALLGWLWVRLLRNRHSALGDALAFTALWLAFDALRGWLLTGFPW
LYIGYSQLDGPLSGLAPVGGVWLLSFAIALSATLLVALPRLRADKPRLAAGILLLIAPWLTGLALKDRAWTQDKGEPLSV
VAVQGNVEQSMKWDPKKLEMQLLLYRDMTFRSRPADLIVWPETAVPILKEHAEGYLTMMAGFAKQRGSALITGVPVRQPN
AEGELRYYNGLTTAGEDAGTYLKQKLVPFGEYVPLQELLRGLIAFFDLPMSDFARGESGQPLLQARGLQIAPYICYEVVY
PEFAAGLAAQSDLLLTVSNDAWFGRSIGPLQHLQMAQMRALEAGRWMIRATNNGITVLIDPYGRITEQIPQFEQAVLYGE
VTPMQGLTPYLRWRSWPLIAVCVLLLGWALVRRKSA

Specific function: Transfers the fatty acyl group on membrane lipoproteins [H]

COG id: COG0815

COG function: function code M; Apolipoprotein N-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1786878, Length=505, Percent_Identity=42.7722772277228, Blast_Score=352, Evalue=4e-98,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004563
- InterPro:   IPR003010 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 2.3.1.- [C]

Molecular weight: Translated: 56847; Mature: 56716

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLACAAIPAQGNPMHWFTRPGWPGNLLALLAGTLTTLSLAPFDIWPLALLSVALLYLGL
CCCEEEECCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
RETGPKQAARRGWCYGFGLFASGVSWVYVSIHDFGAASPPLAGLLTFGFVAGLALFFALL
HCCCHHHHHHCCCEEEHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
GWLWVRLLRNRHSALGDALAFTALWLAFDALRGWLLTGFPWLYIGYSQLDGPLSGLAPVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHCCCCHHCCCCHH
GVWLLSFAIALSATLLVALPRLRADKPRLAAGILLLIAPWLTGLALKDRAWTQDKGEPLS
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCEECCCCCCCCCCCCEE
VVAVQGNVEQSMKWDPKKLEMQLLLYRDMTFRSRPADLIVWPETAVPILKEHAEGYLTMM
EEEEECCHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHH
AGFAKQRGSALITGVPVRQPNAEGELRYYNGLTTAGEDAGTYLKQKLVPFGEYVPLQELL
HHHHHHCCCEEEEECCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHCCCCCCCCCHHHHH
RGLIAFFDLPMSDFARGESGQPLLQARGLQIAPYICYEVVYPEFAAGLAAQSDLLLTVSN
HHHHHHHCCCHHHHCCCCCCCCHHHHCCCEECHHHHHHHHHHHHHHHHCCCCCEEEEEEC
DAWFGRSIGPLQHLQMAQMRALEAGRWMIRATNNGITVLIDPYGRITEQIPQFEQAVLYG
CCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHC
EVTPMQGLTPYLRWRSWPLIAVCVLLLGWALVRRKSA
CCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PLACAAIPAQGNPMHWFTRPGWPGNLLALLAGTLTTLSLAPFDIWPLALLSVALLYLGL
CCEEEECCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
RETGPKQAARRGWCYGFGLFASGVSWVYVSIHDFGAASPPLAGLLTFGFVAGLALFFALL
HCCCHHHHHHCCCEEEHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
GWLWVRLLRNRHSALGDALAFTALWLAFDALRGWLLTGFPWLYIGYSQLDGPLSGLAPVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHCCCCHHCCCCHH
GVWLLSFAIALSATLLVALPRLRADKPRLAAGILLLIAPWLTGLALKDRAWTQDKGEPLS
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCEECCCCCCCCCCCCEE
VVAVQGNVEQSMKWDPKKLEMQLLLYRDMTFRSRPADLIVWPETAVPILKEHAEGYLTMM
EEEEECCHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHH
AGFAKQRGSALITGVPVRQPNAEGELRYYNGLTTAGEDAGTYLKQKLVPFGEYVPLQELL
HHHHHHCCCEEEEECCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHCCCCCCCCCHHHHH
RGLIAFFDLPMSDFARGESGQPLLQARGLQIAPYICYEVVYPEFAAGLAAQSDLLLTVSN
HHHHHHHCCCHHHHCCCCCCCCHHHHCCCEECHHHHHHHHHHHHHHHHCCCCCEEEEEEC
DAWFGRSIGPLQHLQMAQMRALEAGRWMIRATNNGITVLIDPYGRITEQIPQFEQAVLYG
CCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHC
EVTPMQGLTPYLRWRSWPLIAVCVLLLGWALVRRKSA
CCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12928499 [H]