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The map label for this gene is corC [H]

Identifier: 146284076

GI number: 146284076

Start: 4071878

End: 4072720

Strand: Direct

Name: corC [H]

Synonym: PST_3764

Alternate gene names: 146284076

Gene position: 4071878-4072720 (Clockwise)

Preceding gene: 146284075

Following gene: 146284077

Centisome position: 89.15

GC content: 62.04

Gene sequence:

>843_bases
ATGAGCGAAGATCGATCGATCAGCGGGCAGAAGACCTGGCTGGAAAGAATCACCCAGGCTTTTGCCCATGAACCCAAGAA
TCGCCAGGAGCTGCTGGAGATCCTGCGCGAGGCCCACCAGAACAAGCTGCTCGACAACGAGGCGCTGGCCATCGTCGAAG
GCGCCATCCAGGTCGCCGACCTGCAGGTACGCGACATCATGGTGCCGCGGTCGCAAGTGATCAGCATCAAGGCCGACCAG
TCTCCACGCGAATTCCTCCCCGCCATCATCGCTGCCGCGCATTCGCGCTATCCGGTCGTCGGCGAGAGCCTCGACGAGGT
GATCGGCGTGCTGCTGGCCAAGGATCTGCTGCCGCTGATCCTCAAGGAGGACCAGCAGAACTTCGACATCAAGGACCTGC
TGCGCCCGGCCACCTTCGTGCCCGAATCCAAGCGCCTCAACGTGCTGTTGCGCGAGTTCCGCGCCAACCACAACCACATG
GCCATCGTCATCGACGAATACGGCGGCGTCGCCGGCCTGGTGACCATCGAAGACGTGCTCGAGCAGATCGTCGGCGATAT
CGAGGACGAGCACGACGTCGAGGAAGACAGTTATATCCGACCGCTGCCCAGCGGTGACTTCCTGGTCAAGGCGCTGACGC
CGATCGACAGCTTCAACGAGTATTTTGGCAGCGCCTTCCCCGACGACGAGTTCGATACCGTTGCCGGCTTGGTGATGAGC
ACCTTTGGCCATCTGCCCAAGCGCAACGAGGTGACCGAGATCGACGGTTTCCGCGTTCGCGTATTGAACGCCGACAGCCG
CCGCGTGCACATGCTGCGCCTGAGCCGCCTGGAAAGCGCTTGA

Upstream 100 bases:

>100_bases
AGCGCTTGAGCGCCAGCTGCTGGCTGAACTGGGGCACCCCGACCCCTATGCTGAAGATTCGCCCGAAACGGGCATTTGCA
AGGACTCTTGAGTCAACGAC

Downstream 100 bases:

>100_bases
CCTGCAACTTGCCGCCCGCTTGCGGGCGGCAAGCGATCGGCCAGCTTGCCGGATCGCCTCGTTGCCCTTAGCCTGCGCCG
CAATCCCCGCCCAAGGAAAC

Product: metal ion transporter, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 280; Mature: 279

Protein sequence:

>280_residues
MSEDRSISGQKTWLERITQAFAHEPKNRQELLEILREAHQNKLLDNEALAIVEGAIQVADLQVRDIMVPRSQVISIKADQ
SPREFLPAIIAAAHSRYPVVGESLDEVIGVLLAKDLLPLILKEDQQNFDIKDLLRPATFVPESKRLNVLLREFRANHNHM
AIVIDEYGGVAGLVTIEDVLEQIVGDIEDEHDVEEDSYIRPLPSGDFLVKALTPIDSFNEYFGSAFPDDEFDTVAGLVMS
TFGHLPKRNEVTEIDGFRVRVLNADSRRVHMLRLSRLESA

Sequences:

>Translated_280_residues
MSEDRSISGQKTWLERITQAFAHEPKNRQELLEILREAHQNKLLDNEALAIVEGAIQVADLQVRDIMVPRSQVISIKADQ
SPREFLPAIIAAAHSRYPVVGESLDEVIGVLLAKDLLPLILKEDQQNFDIKDLLRPATFVPESKRLNVLLREFRANHNHM
AIVIDEYGGVAGLVTIEDVLEQIVGDIEDEHDVEEDSYIRPLPSGDFLVKALTPIDSFNEYFGSAFPDDEFDTVAGLVMS
TFGHLPKRNEVTEIDGFRVRVLNADSRRVHMLRLSRLESA
>Mature_279_residues
SEDRSISGQKTWLERITQAFAHEPKNRQELLEILREAHQNKLLDNEALAIVEGAIQVADLQVRDIMVPRSQVISIKADQS
PREFLPAIIAAAHSRYPVVGESLDEVIGVLLAKDLLPLILKEDQQNFDIKDLLRPATFVPESKRLNVLLREFRANHNHMA
IVIDEYGGVAGLVTIEDVLEQIVGDIEDEHDVEEDSYIRPLPSGDFLVKALTPIDSFNEYFGSAFPDDEFDTVAGLVMST
FGHLPKRNEVTEIDGFRVRVLNADSRRVHMLRLSRLESA

Specific function: Plays a role in the transport of magnesium and cobalt ions [H]

COG id: COG4535

COG function: function code P; Putative Mg2+ and Co2+ transporter CorC

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=209, Percent_Identity=26.7942583732057, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI94681046, Length=189, Percent_Identity=29.1005291005291, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI40068055, Length=184, Percent_Identity=29.8913043478261, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI40068053, Length=184, Percent_Identity=29.8913043478261, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1786879, Length=275, Percent_Identity=50.5454545454545, Blast_Score=255, Evalue=2e-69,
Organism=Escherichia coli, GI145693175, Length=238, Percent_Identity=27.7310924369748, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1788119, Length=233, Percent_Identity=30.9012875536481, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1790664, Length=231, Percent_Identity=25.1082251082251, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI87082033, Length=288, Percent_Identity=25.6944444444444, Blast_Score=84, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 31570; Mature: 31439

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEDRSISGQKTWLERITQAFAHEPKNRQELLEILREAHQNKLLDNEALAIVEGAIQVAD
CCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
LQVRDIMVPRSQVISIKADQSPREFLPAIIAAAHSRYPVVGESLDEVIGVLLAKDLLPLI
CHHHHEECCCHHEEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
LKEDQQNFDIKDLLRPATFVPESKRLNVLLREFRANHNHMAIVIDEYGGVAGLVTIEDVL
HHCCCCCCCHHHHHCCHHCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCEEEEHHHHHHH
EQIVGDIEDEHDVEEDSYIRPLPSGDFLVKALTPIDSFNEYFGSAFPDDEFDTVAGLVMS
HHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHH
TFGHLPKRNEVTEIDGFRVRVLNADSRRVHMLRLSRLESA
HHCCCCCCCCCEECCCEEEEEECCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
SEDRSISGQKTWLERITQAFAHEPKNRQELLEILREAHQNKLLDNEALAIVEGAIQVAD
CCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
LQVRDIMVPRSQVISIKADQSPREFLPAIIAAAHSRYPVVGESLDEVIGVLLAKDLLPLI
CHHHHEECCCHHEEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
LKEDQQNFDIKDLLRPATFVPESKRLNVLLREFRANHNHMAIVIDEYGGVAGLVTIEDVL
HHCCCCCCCHHHHHCCHHCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCEEEEHHHHHHH
EQIVGDIEDEHDVEEDSYIRPLPSGDFLVKALTPIDSFNEYFGSAFPDDEFDTVAGLVMS
HHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHH
TFGHLPKRNEVTEIDGFRVRVLNADSRRVHMLRLSRLESA
HHCCCCCCCCCEECCCEEEEEECCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]