Click here to switch to the map view.

The map label for this gene is ureC [H]

Identifier: 146284041

GI number: 146284041

Start: 4031583

End: 4033364

Strand: Direct

Name: ureC [H]

Synonym: PST_3729

Alternate gene names: 146284041

Gene position: 4031583-4033364 (Clockwise)

Preceding gene: 146284040

Following gene: 146284042

Centisome position: 88.27

GC content: 65.71

Gene sequence:

>1782_bases
GTGGAGAACGCCGAAGGCTTTTCCACCGTGAACAGGATCGGTGGATGGCTTCGGCCATCCACCCTACGCGAGACGATACG
GATGAAGATTTCCCGCCAAGCCTATGCCGACATGTTCGGCCCCACCGTTGGCGACAAGGTGCGCCTGGCCGACACCGACC
TGTGGATCGAAGTCGAAAAAGACTTCACCACCTATGGCGAAGAGGTGAAGTTCGGCGGCGGCAAGGTGATCCGCGACGGC
ATGGGCCAGAGCCAGCTGTGCGCCGCCGAGGTGGTCGATACCCTGATCACCAACGCGCTGATCCTCGACCACTGGGGCAT
CGTCAAGGCCGACGTGGGCCTCAAGGACGGCCGCATCGCCGCCATCGGCAAGGCCGGCAACCCGGACATTCAGCCCGATG
TGACCATCGCGATCGGCGCCAGCACCGAAGTGATCGCCGGCGAAGGCATGATCCTCACCGCCGGCGGCATCGACTCGCAT
ATTCACTTCATCTGCCCGCAGCAGATCGAAGAGGCGCTGATGAGCGGCGTGACCACCATGATCGGCGGCGGCACGGGTCC
GGCCACCGGCACCAACGCCACCACGGTGACGCCCGGCCCTTGGCACATGGCGATGATGCTCAAGGCCGCCGACGCCTTCC
CGATGAACATCGGTTTTACCGGCAAGGGCAACGCCTCGCTGCCCGAGCCGCTGATCGAGCAGGTCAAGGCCGGTGCCATC
GGCCTCAAGCTGCACGAGGACTGGGGCACCACCCCGGCGGCCATCGACAACTGCCTGTCGGTCGCCGATCAGTACGACGT
GCAGGTGGCCATCCATACCGACACGCTGAACGAATCGGGCTTCGTCGAGACCACCCTCGGCGCGTTCAAGGGCCGCACCA
TCCACACCTACCACACCGAAGGCGCTGGTGGCGGCCACGCGCCCGACATCATCAAGGCCTGCGGCTTCGCCAACGTGCTG
CCCAGCTCGACCAACCCGACCCGGCCGTTCACCCGCAACACCATCGACGAGCACCTGGACATGCTCATGGTCTGCCACCA
CCTCGATCCGAGCATCGCCGAGGACGTGGCCTTCGCCGAGAGCCGTATCCGCCGCGAGACCATCGCCGCCGAAGACATCC
TGCATGATCTCGGCGCGTTCTCCATGATCAGCTCCGACAGCCAGGCCATGGGCCGCGTCGGCGAGGTCATCACCCGCACC
TGGCAGACCGCCGACAAGATGAAGAAGCAGCGCGGCGCCCTGCCCGGCGACGGCGCGGGCAACGACAACTTCCGCGCCAA
ACGCTACATCGCCAAGTACACCATCAACCCGGCGATCACCCACGGCGTCAGCCACGAGGTGGGCTCGATCGAAGTGGGCA
AGTGGGCCGACCTGGTGCTCTGGCGCCCGGCCTTCTTCGGCGTCAAGCCGACACTGATCCTCAAGGGCGGCGCCATTGCC
GCGAGCCTGATGGGCGACGCCAACGCCTCGATCCCGACGCCGCAGCCGGTGCACTACCGGCCGATGTTCGCCTGTTACGG
CGGTTCGCTGCACGCGTCGAGCTTCACCTTCATCAGCCAGGCCGCCTTCGAGGCCGGCGTGCCCGAGCAGCTGGGGCTGA
AGAAGAAGATCGGCGTGGTCCGGGGCTGCCGCCAGGTGCAGAAGAAGGACCTGATCCACAACGACTACACACCAGACATC
CAGGTCGACCCGCAGAACTATCAGGTGCGCGCCGATGGCCAGCTGCTCTGGTGCGAGCCGGCCGAAGTGCTGCCGATGGC
GCAGCGCTACTTTCTGTTCTGA

Upstream 100 bases:

>100_bases
GCCGCGAGGTGGAGCTGGTCGAGCTGGCCGGCGAGCGCCGGGTGTTCGGCTTTGCCGGGCGGGTAATGGGCGCGCTCTAG
GGCACAGCGCTTTTCGTAGG

Downstream 100 bases:

>100_bases
TCGACTGATGCGTAACCAGTCGCCGCTCACCGGCGCGGCGCAACCCGCTCCGCTCGGCTGAGCGCCGCCTGCAGAAGAGG
TCGGCCATGTTAAAGTGGCC

Product: urease subunit alpha

Products: NA

Alternate protein names: Urea amidohydrolase subunit alpha 2 [H]

Number of amino acids: Translated: 593; Mature: 593

Protein sequence:

>593_residues
MENAEGFSTVNRIGGWLRPSTLRETIRMKISRQAYADMFGPTVGDKVRLADTDLWIEVEKDFTTYGEEVKFGGGKVIRDG
MGQSQLCAAEVVDTLITNALILDHWGIVKADVGLKDGRIAAIGKAGNPDIQPDVTIAIGASTEVIAGEGMILTAGGIDSH
IHFICPQQIEEALMSGVTTMIGGGTGPATGTNATTVTPGPWHMAMMLKAADAFPMNIGFTGKGNASLPEPLIEQVKAGAI
GLKLHEDWGTTPAAIDNCLSVADQYDVQVAIHTDTLNESGFVETTLGAFKGRTIHTYHTEGAGGGHAPDIIKACGFANVL
PSSTNPTRPFTRNTIDEHLDMLMVCHHLDPSIAEDVAFAESRIRRETIAAEDILHDLGAFSMISSDSQAMGRVGEVITRT
WQTADKMKKQRGALPGDGAGNDNFRAKRYIAKYTINPAITHGVSHEVGSIEVGKWADLVLWRPAFFGVKPTLILKGGAIA
ASLMGDANASIPTPQPVHYRPMFACYGGSLHASSFTFISQAAFEAGVPEQLGLKKKIGVVRGCRQVQKKDLIHNDYTPDI
QVDPQNYQVRADGQLLWCEPAEVLPMAQRYFLF

Sequences:

>Translated_593_residues
MENAEGFSTVNRIGGWLRPSTLRETIRMKISRQAYADMFGPTVGDKVRLADTDLWIEVEKDFTTYGEEVKFGGGKVIRDG
MGQSQLCAAEVVDTLITNALILDHWGIVKADVGLKDGRIAAIGKAGNPDIQPDVTIAIGASTEVIAGEGMILTAGGIDSH
IHFICPQQIEEALMSGVTTMIGGGTGPATGTNATTVTPGPWHMAMMLKAADAFPMNIGFTGKGNASLPEPLIEQVKAGAI
GLKLHEDWGTTPAAIDNCLSVADQYDVQVAIHTDTLNESGFVETTLGAFKGRTIHTYHTEGAGGGHAPDIIKACGFANVL
PSSTNPTRPFTRNTIDEHLDMLMVCHHLDPSIAEDVAFAESRIRRETIAAEDILHDLGAFSMISSDSQAMGRVGEVITRT
WQTADKMKKQRGALPGDGAGNDNFRAKRYIAKYTINPAITHGVSHEVGSIEVGKWADLVLWRPAFFGVKPTLILKGGAIA
ASLMGDANASIPTPQPVHYRPMFACYGGSLHASSFTFISQAAFEAGVPEQLGLKKKIGVVRGCRQVQKKDLIHNDYTPDI
QVDPQNYQVRADGQLLWCEPAEVLPMAQRYFLF
>Mature_593_residues
MENAEGFSTVNRIGGWLRPSTLRETIRMKISRQAYADMFGPTVGDKVRLADTDLWIEVEKDFTTYGEEVKFGGGKVIRDG
MGQSQLCAAEVVDTLITNALILDHWGIVKADVGLKDGRIAAIGKAGNPDIQPDVTIAIGASTEVIAGEGMILTAGGIDSH
IHFICPQQIEEALMSGVTTMIGGGTGPATGTNATTVTPGPWHMAMMLKAADAFPMNIGFTGKGNASLPEPLIEQVKAGAI
GLKLHEDWGTTPAAIDNCLSVADQYDVQVAIHTDTLNESGFVETTLGAFKGRTIHTYHTEGAGGGHAPDIIKACGFANVL
PSSTNPTRPFTRNTIDEHLDMLMVCHHLDPSIAEDVAFAESRIRRETIAAEDILHDLGAFSMISSDSQAMGRVGEVITRT
WQTADKMKKQRGALPGDGAGNDNFRAKRYIAKYTINPAITHGVSHEVGSIEVGKWADLVLWRPAFFGVKPTLILKGGAIA
ASLMGDANASIPTPQPVHYRPMFACYGGSLHASSFTFISQAAFEAGVPEQLGLKKKIGVVRGCRQVQKKDLIHNDYTPDI
QVDPQNYQVRADGQLLWCEPAEVLPMAQRYFLF

Specific function: Unknown

COG id: COG0804

COG function: function code E; Urea amidohydrolase (urease) alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 urease domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059
- InterPro:   IPR011612
- InterPro:   IPR005848
- InterPro:   IPR017951
- InterPro:   IPR017950 [H]

Pfam domain/function: PF01979 Amidohydro_1; PF00449 Urease_alpha [H]

EC number: =3.5.1.5 [H]

Molecular weight: Translated: 63797; Mature: 63797

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: PS01120 UREASE_1 ; PS00145 UREASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENAEGFSTVNRIGGWLRPSTLRETIRMKISRQAYADMFGPTVGDKVRLADTDLWIEVEK
CCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCEEEEEECC
DFTTYGEEVKFGGGKVIRDGMGQSQLCAAEVVDTLITNALILDHWGIVKADVGLKDGRIA
CCCCCCCEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHHEECCCEEEECCCCCCCCEE
AIGKAGNPDIQPDVTIAIGASTEVIAGEGMILTAGGIDSHIHFICPQQIEEALMSGVTTM
EEECCCCCCCCCCEEEEECCCCEEEECCCEEEEECCCCCCEEEECHHHHHHHHHHCHHHH
IGGGTGPATGTNATTVTPGPWHMAMMLKAADAFPMNIGFTGKGNASLPEPLIEQVKAGAI
HCCCCCCCCCCCCCEECCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHCCCEE
GLKLHEDWGTTPAAIDNCLSVADQYDVQVAIHTDTLNESGFVETTLGAFKGRTIHTYHTE
EEEEECCCCCCHHHHHHHHHHHCCCEEEEEEEECCCCCCCCEEHHHHHHCCCEEEEEECC
GAGGGHAPDIIKACGFANVLPSSTNPTRPFTRNTIDEHLDMLMVCHHLDPSIAEDVAFAE
CCCCCCCHHHHHHCCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHH
SRIRRETIAAEDILHDLGAFSMISSDSQAMGRVGEVITRTWQTADKMKKQRGALPGDGAG
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
NDNFRAKRYIAKYTINPAITHGVSHEVGSIEVGKWADLVLWRPAFFGVKPTLILKGGAIA
CCCCHHHEEEEEEECCHHHHCCCCCCCCCEECCCCCCEEEECHHHHCCCCEEEEECCCEE
ASLMGDANASIPTPQPVHYRPMFACYGGSLHASSFTFISQAAFEAGVPEQLGLKKKIGVV
EEHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCHHHCCHHHHHHH
RGCRQVQKKDLIHNDYTPDIQVDPQNYQVRADGQLLWCEPAEVLPMAQRYFLF
HHHHHHHHHHHHCCCCCCCEEECCCCEEEEECCEEEEECCHHHHHHHHHHHCC
>Mature Secondary Structure
MENAEGFSTVNRIGGWLRPSTLRETIRMKISRQAYADMFGPTVGDKVRLADTDLWIEVEK
CCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCEEEEEECC
DFTTYGEEVKFGGGKVIRDGMGQSQLCAAEVVDTLITNALILDHWGIVKADVGLKDGRIA
CCCCCCCEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHHEECCCEEEECCCCCCCCEE
AIGKAGNPDIQPDVTIAIGASTEVIAGEGMILTAGGIDSHIHFICPQQIEEALMSGVTTM
EEECCCCCCCCCCEEEEECCCCEEEECCCEEEEECCCCCCEEEECHHHHHHHHHHCHHHH
IGGGTGPATGTNATTVTPGPWHMAMMLKAADAFPMNIGFTGKGNASLPEPLIEQVKAGAI
HCCCCCCCCCCCCCEECCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHCCCEE
GLKLHEDWGTTPAAIDNCLSVADQYDVQVAIHTDTLNESGFVETTLGAFKGRTIHTYHTE
EEEEECCCCCCHHHHHHHHHHHCCCEEEEEEEECCCCCCCCEEHHHHHHCCCEEEEEECC
GAGGGHAPDIIKACGFANVLPSSTNPTRPFTRNTIDEHLDMLMVCHHLDPSIAEDVAFAE
CCCCCCCHHHHHHCCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHH
SRIRRETIAAEDILHDLGAFSMISSDSQAMGRVGEVITRTWQTADKMKKQRGALPGDGAG
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
NDNFRAKRYIAKYTINPAITHGVSHEVGSIEVGKWADLVLWRPAFFGVKPTLILKGGAIA
CCCCHHHEEEEEEECCHHHHCCCCCCCCCEECCCCCCEEEECHHHHCCCCEEEEECCCEE
ASLMGDANASIPTPQPVHYRPMFACYGGSLHASSFTFISQAAFEAGVPEQLGLKKKIGVV
EEHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCHHHCCHHHHHHH
RGCRQVQKKDLIHNDYTPDIQVDPQNYQVRADGQLLWCEPAEVLPMAQRYFLF
HHHHHHHHHHHHCCCCCCCEEECCCCEEEEECCEEEEECCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA