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The map label for this gene is fis [C]

Identifier: 146283598

GI number: 146283598

Start: 3544985

End: 3545305

Strand: Direct

Name: fis [C]

Synonym: PST_3278

Alternate gene names: 146283598

Gene position: 3544985-3545305 (Clockwise)

Preceding gene: 146283597

Following gene: 146283599

Centisome position: 77.61

GC content: 57.32

Gene sequence:

>321_bases
ATGACGCTGTTGAATGAAACATTGGTAAGTGGAACAACATCCGTGAGTGACAACGTGAACCTCAAGCAGCACCTGAACAC
GCCGAGCGAAGCAGGGCAGACGTTGCGCGGCAGCGTCGAGAAGGCGCTGCACAACTATTTCGCCCGTCTCGAAGGTGCCG
ACGTCACGGACGTTTACAACCTCGTGCTCTCCGAAGTGGAGGCGCCGCTGCTGGAAACCGTGATGCATTACGTGAAGGGC
AACCAGACCAAGGCATCCGAGCTGCTCGGCCTGAATCGCGGCACCCTGCGCAAGAAACTCAAACAGTACGACCTGCTCTG
A

Upstream 100 bases:

>100_bases
ATCATCTGGAAGACAGGGATGCGCAAGGCTCCAGCATCCGGCAATTCTTTGCCGAACAACGCTCTGGGCCTGGCTCGGTG
GATGGAACAGAGGTGGCCGC

Downstream 100 bases:

>100_bases
AGCGACAGCTGGCAGACTCGGTCGCCCGGTCCTGCCAGCTTCGCGGCCTCAAGCCTGTAGCCTCTAGGAACCGTCAATGA
CCGACCAAACCACCCGCCTT

Product: DNA-binding protein Fis

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 106; Mature: 105

Protein sequence:

>106_residues
MTLLNETLVSGTTSVSDNVNLKQHLNTPSEAGQTLRGSVEKALHNYFARLEGADVTDVYNLVLSEVEAPLLETVMHYVKG
NQTKASELLGLNRGTLRKKLKQYDLL

Sequences:

>Translated_106_residues
MTLLNETLVSGTTSVSDNVNLKQHLNTPSEAGQTLRGSVEKALHNYFARLEGADVTDVYNLVLSEVEAPLLETVMHYVKG
NQTKASELLGLNRGTLRKKLKQYDLL
>Mature_105_residues
TLLNETLVSGTTSVSDNVNLKQHLNTPSEAGQTLRGSVEKALHNYFARLEGADVTDVYNLVLSEVEAPLLETVMHYVKGN
QTKASELLGLNRGTLRKKLKQYDLL

Specific function: Activates Ribosomal RNA Transcription. Plays A Direct Role In Upstream Activation Of rRNA Promoters. Binds To A Recombinational Enhancer Sequence That Is Required To Stimulate Hin-Mediated DNA Inversion. Prevents Initiation Of DNA Replication From Oric.

COG id: COG2901

COG function: function code KL; Factor for inversion stimulation Fis, transcriptional activator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transcriptional regulatory fis family [H]

Homologues:

Organism=Escherichia coli, GI1789661, Length=71, Percent_Identity=63.3802816901408, Blast_Score=100, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005412
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197 [H]

Pfam domain/function: PF02954 HTH_8 [H]

EC number: NA

Molecular weight: Translated: 11715; Mature: 11583

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLLNETLVSGTTSVSDNVNLKQHLNTPSEAGQTLRGSVEKALHNYFARLEGADVTDVYN
CCCHHHHHHCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LVLSEVEAPLLETVMHYVKGNQTKASELLGLNRGTLRKKLKQYDLL
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
TLLNETLVSGTTSVSDNVNLKQHLNTPSEAGQTLRGSVEKALHNYFARLEGADVTDVYN
CCHHHHHHCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LVLSEVEAPLLETVMHYVKGNQTKASELLGLNRGTLRKKLKQYDLL
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]