Click here to switch to the map view.

The map label for this gene is 146283583

Identifier: 146283583

GI number: 146283583

Start: 3529932

End: 3531575

Strand: Direct

Name: 146283583

Synonym: PST_3263

Alternate gene names: NA

Gene position: 3529932-3531575 (Clockwise)

Preceding gene: 146283579

Following gene: 146283584

Centisome position: 77.29

GC content: 64.23

Gene sequence:

>1644_bases
ATGCCGGCGACTTTACGACTGTGTGGACTGCTTCGCAGTGGACTCGCACGCCCCGTTCAAGAACTTCGACAAGGAATGAC
CGTGAGCCAAGCACTGATCGCCGCCCTGCAGAATCCTGCCCTGTATCCGCACCCCACCGAAAGCTTTCGGGTCATCGAAA
CCCATATTTCCTGGGTGATCCTCACCGGCCAGTACGCCTACAAGATCAAGAAGCCGGTGGACTTCGGCTTCCTCAACTTC
ACCGATCTGGCCTCGCGCAAGCATTTCTGCGAAGAAGAGCTGCGCCTCAACCAGCGCATGGCACCTGACCTCTACCTGGA
AGTGTTGCCTGTCACCGGCTCGCCTGATGCTCCGGTGATCGGCGGCGACGGCAATCCCTTCGAGTACGTGCTGAAGATGC
GCGAGTTCCCGCAGTCCCAGCTGCTGGCCGAGGTCCAGGCCCGCGGCGAGCTGACCGATGCGCATATCGACGCTCTGGCC
GAGCAGATCGCAAGCTTCCACCTCAGCACCCCGCAGGTACAGCCGGACCACGCGCTGAACAGCGCCGATGCGATCGTCGC
ACCGATGCGGCAGAACTTCGAACAGATACGCCCGCTGCTCAGCGAGCCGGAAGACCTGCGCCAGCTGGACGCTCTCGAAG
ACTGGACCGAAACCAGCATCACGCGCCTGCGCCCACTGCTCGAACAGCGCTGCCAGCAAGGCTTCGTTCGCGAATGCCAT
GGCGACCTTCACCTGGGCAATGCCACGCTGATCGATGGCAAGGTCGTGCTGTTCGACTGCATCGAATTCAACGAGCCGTT
CCGCCTGATCGATGTCGCCTCGGATGCCGCCTTCCTGGCCATGGACCTTGAGGATCGCGGACTGAAATGCCAGGCCCGGC
GCTTCATCAATGGCTGGCTGGAGCACACCGGCGACTATGCCGCGCTGGCGTTGCTCAACCTCTATAAGGCCTATCGTGCG
TTGGTTCGCGGCAAGGTCAGCCTGTTCCGCCTGTATCAGGAGCAGGACGCCGTGCAGCGCAAGGTTATCCTGCGCCAGTA
CCGCAGTTACGCCAATCTCGCCGAAAGCTACAGCGCGATTCCGTCCCGCTTCCTCGCCATCACTCACGGTGTATCGGCCG
TCGGCAAGAGTCACGTCGCGCTACGCCTGGTCGAAGCGCTCGGCGCGGTGCGTCTGCGCTCGGATGTCGAGCGCAAGCGT
CTGCACGGCGAGCAGGCCGAGGCGCAGGCAGGCCAGCTCGATAGCGGCATCTACAGCCAGCAAGCCAGCGAAGCGACCTA
TCGCCACCTGCACCAGCTGGCGACTGCCGCACTGCAGGCCGGGTTCGCCGTGGTCATCGACGCGGCCTACCTGAAGCAGT
CGCAACGCCAGGCGGCATGGCAGGCAGCCGAAGCGACCGGCGTGCCGTTCCTCATCCTCGATTGCGAGGCTCCGGAAGCG
GTGATCGCCCAGTGGCTCGCTCAGCGTCAGGCCGAAGGCACCGATCCGTCCGACGCGACAATGGAGGTGGTCCGCGCGCA
GCAGGCCAGCCGCGAGCCGCTGAGCGACAGCGAGCGCCTGCATAGCTGCCGGGTCCAGACGCAGGATGCCGGCAGCCTCG
ACGAGCTGGTCGCCAACATCCGCCAGCGCCTGCCGGGGCTTTGA

Upstream 100 bases:

>100_bases
GGGGGGAGCGAGGTTTAGTCATGGCGGCGCATTATACGCACTTTGCCGCAGCGGATTGACGGCCTCTCAGCGGTTTGCAG
CGCAACGCTCAGCGGCCATA

Downstream 100 bases:

>100_bases
CCGTTAGGCACCGTCGCGGGCAGGCCGCGGCGGTGCCTCTATACTCCCGGTATAACAACCGTGGGAATGCCTATGCCTGC
CAGCGAACCCCGCCTCTCCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 547; Mature: 546

Protein sequence:

>547_residues
MPATLRLCGLLRSGLARPVQELRQGMTVSQALIAALQNPALYPHPTESFRVIETHISWVILTGQYAYKIKKPVDFGFLNF
TDLASRKHFCEEELRLNQRMAPDLYLEVLPVTGSPDAPVIGGDGNPFEYVLKMREFPQSQLLAEVQARGELTDAHIDALA
EQIASFHLSTPQVQPDHALNSADAIVAPMRQNFEQIRPLLSEPEDLRQLDALEDWTETSITRLRPLLEQRCQQGFVRECH
GDLHLGNATLIDGKVVLFDCIEFNEPFRLIDVASDAAFLAMDLEDRGLKCQARRFINGWLEHTGDYAALALLNLYKAYRA
LVRGKVSLFRLYQEQDAVQRKVILRQYRSYANLAESYSAIPSRFLAITHGVSAVGKSHVALRLVEALGAVRLRSDVERKR
LHGEQAEAQAGQLDSGIYSQQASEATYRHLHQLATAALQAGFAVVIDAAYLKQSQRQAAWQAAEATGVPFLILDCEAPEA
VIAQWLAQRQAEGTDPSDATMEVVRAQQASREPLSDSERLHSCRVQTQDAGSLDELVANIRQRLPGL

Sequences:

>Translated_547_residues
MPATLRLCGLLRSGLARPVQELRQGMTVSQALIAALQNPALYPHPTESFRVIETHISWVILTGQYAYKIKKPVDFGFLNF
TDLASRKHFCEEELRLNQRMAPDLYLEVLPVTGSPDAPVIGGDGNPFEYVLKMREFPQSQLLAEVQARGELTDAHIDALA
EQIASFHLSTPQVQPDHALNSADAIVAPMRQNFEQIRPLLSEPEDLRQLDALEDWTETSITRLRPLLEQRCQQGFVRECH
GDLHLGNATLIDGKVVLFDCIEFNEPFRLIDVASDAAFLAMDLEDRGLKCQARRFINGWLEHTGDYAALALLNLYKAYRA
LVRGKVSLFRLYQEQDAVQRKVILRQYRSYANLAESYSAIPSRFLAITHGVSAVGKSHVALRLVEALGAVRLRSDVERKR
LHGEQAEAQAGQLDSGIYSQQASEATYRHLHQLATAALQAGFAVVIDAAYLKQSQRQAAWQAAEATGVPFLILDCEAPEA
VIAQWLAQRQAEGTDPSDATMEVVRAQQASREPLSDSERLHSCRVQTQDAGSLDELVANIRQRLPGL
>Mature_546_residues
PATLRLCGLLRSGLARPVQELRQGMTVSQALIAALQNPALYPHPTESFRVIETHISWVILTGQYAYKIKKPVDFGFLNFT
DLASRKHFCEEELRLNQRMAPDLYLEVLPVTGSPDAPVIGGDGNPFEYVLKMREFPQSQLLAEVQARGELTDAHIDALAE
QIASFHLSTPQVQPDHALNSADAIVAPMRQNFEQIRPLLSEPEDLRQLDALEDWTETSITRLRPLLEQRCQQGFVRECHG
DLHLGNATLIDGKVVLFDCIEFNEPFRLIDVASDAAFLAMDLEDRGLKCQARRFINGWLEHTGDYAALALLNLYKAYRAL
VRGKVSLFRLYQEQDAVQRKVILRQYRSYANLAESYSAIPSRFLAITHGVSAVGKSHVALRLVEALGAVRLRSDVERKRL
HGEQAEAQAGQLDSGIYSQQASEATYRHLHQLATAALQAGFAVVIDAAYLKQSQRQAAWQAAEATGVPFLILDCEAPEAV
IAQWLAQRQAEGTDPSDATMEVVRAQQASREPLSDSERLHSCRVQTQDAGSLDELVANIRQRLPGL

Specific function: Some isolated peptides of this protein are able to bind to human U937 monocytoblastic and A549 epithelial cell lines [H]

COG id: COG2187

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Secreted, cell wall [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011009
- InterPro:   IPR010488 [H]

Pfam domain/function: PF06414 Zeta_toxin [H]

EC number: NA

Molecular weight: Translated: 60963; Mature: 60832

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPATLRLCGLLRSGLARPVQELRQGMTVSQALIAALQNPALYPHPTESFRVIETHISWVI
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCHHHHEEEEEEEE
LTGQYAYKIKKPVDFGFLNFTDLASRKHFCEEELRLNQRMAPDLYLEVLPVTGSPDAPVI
EECCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEE
GGDGNPFEYVLKMREFPQSQLLAEVQARGELTDAHIDALAEQIASFHLSTPQVQPDHALN
CCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
SADAIVAPMRQNFEQIRPLLSEPEDLRQLDALEDWTETSITRLRPLLEQRCQQGFVRECH
CCHHHHHHHHHCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GDLHLGNATLIDGKVVLFDCIEFNEPFRLIDVASDAAFLAMDLEDRGLKCQARRFINGWL
CCEEECCEEEECCCEEEEEEECCCCCEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHH
EHTGDYAALALLNLYKAYRALVRGKVSLFRLYQEQDAVQRKVILRQYRSYANLAESYSAI
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PSRFLAITHGVSAVGKSHVALRLVEALGAVRLRSDVERKRLHGEQAEAQAGQLDSGIYSQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHH
QASEATYRHLHQLATAALQAGFAVVIDAAYLKQSQRQAAWQAAEATGVPFLILDCEAPEA
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHH
VIAQWLAQRQAEGTDPSDATMEVVRAQQASREPLSDSERLHSCRVQTQDAGSLDELVANI
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHH
RQRLPGL
HHHCCCC
>Mature Secondary Structure 
PATLRLCGLLRSGLARPVQELRQGMTVSQALIAALQNPALYPHPTESFRVIETHISWVI
CCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCHHHHEEEEEEEE
LTGQYAYKIKKPVDFGFLNFTDLASRKHFCEEELRLNQRMAPDLYLEVLPVTGSPDAPVI
EECCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEE
GGDGNPFEYVLKMREFPQSQLLAEVQARGELTDAHIDALAEQIASFHLSTPQVQPDHALN
CCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
SADAIVAPMRQNFEQIRPLLSEPEDLRQLDALEDWTETSITRLRPLLEQRCQQGFVRECH
CCHHHHHHHHHCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GDLHLGNATLIDGKVVLFDCIEFNEPFRLIDVASDAAFLAMDLEDRGLKCQARRFINGWL
CCEEECCEEEECCCEEEEEEECCCCCEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHH
EHTGDYAALALLNLYKAYRALVRGKVSLFRLYQEQDAVQRKVILRQYRSYANLAESYSAI
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PSRFLAITHGVSAVGKSHVALRLVEALGAVRLRSDVERKRLHGEQAEAQAGQLDSGIYSQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHH
QASEATYRHLHQLATAALQAGFAVVIDAAYLKQSQRQAAWQAAEATGVPFLILDCEAPEA
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHH
VIAQWLAQRQAEGTDPSDATMEVVRAQQASREPLSDSERLHSCRVQTQDAGSLDELVANI
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHH
RQRLPGL
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]