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The map label for this gene is hlyB [H]

Identifier: 146283468

GI number: 146283468

Start: 3381356

End: 3382978

Strand: Direct

Name: hlyB [H]

Synonym: PST_3141

Alternate gene names: 146283468

Gene position: 3381356-3382978 (Clockwise)

Preceding gene: 146283467

Following gene: 146283469

Centisome position: 74.03

GC content: 66.67

Gene sequence:

>1623_bases
ATGCTCCAGAAGTCCCTGCGCGCGCAGATCCTCGCGCTGATCGGCGGCAGCCTGCTGCTGACGCTCCTCATCGCCCTCGG
CTGCATCCGCATGCTCAGCAGCGATATCGACCAATTCCAGACGCTGCTCGACGGCCCCCTAGCCGAGCTGCAACTGATCG
ACGAGGCCAACCTCGAGTTCAAGGTGCAGGTGCAGGAATGGAAGAACGTGCTGCTGCGCGGCAAGCAGCTCGAAAATCGC
AACCGCTACTGGAGCCAGTTCGAGGCACAGGAAGCCAAGGTGCAGAAGGTTCTTGGCGATCTGCTCGTGCTGAGTGCCGA
CGAACCGGAGCTGGCCGGACAGATCGAGCGCCTGCGCAACGAGCATCGAACGCTGGGCGGCGCCTACCGCAAGGGCCTGG
ACGCCTTCATCGCCGCCGGCAGCGACCCGCTTGCCGGTGATGCTGCAGTAGCCGGGATCGACCGTGCCACAAGCGCCCAG
CTCAGCGAACTGGTCAAGCAGCTGCATGCGGCCGCCAGGCAGCGTTCGGAGGCGATACAGGCCGATGCCGAAGCCACCGC
GCTGCTCGGCCCGGTCATCATGATCCTGGCCGGTGTGGTGGTGGCGCTACTCAGCCTGTGGCTGGTCAATCGACGCATCA
TCGAGCCGATCCGCACGCTGATCGAGCACATCGCGCGTCTCAGCCAGGGCAAGTTCGCCGAGCGGGTGGACGCCAGCCGC
GCCGACGAACTCGGCCGGCTCGCGGTTGCCGCCAACGTGCTGCGCGATTTTCTCGCCGACACCTTCACCCGCCTACAGCA
GAGCACCTCCAATCTGGACAGCGCTAGCGGCGAACTGAACGCCATCGCCAGGCTGATGGCCGATGGCGCCCGCGAGCAGT
TCTCGCGCACCGATCAGGTCGCCACTGCCATGCATGAGATGTCGGCAACTGCCCAGGAAGTCTCGCGCCATGCCGCCGAA
GCGGCGCAGGCCGCCGATGCCGCCGATCACGCCGCGCAACAGGGCGAGGCGGTGATGCGCGGCACCATCGCCAGCATCAC
CGACATGAGCAGCGAAATCGCCAGCACTGCCGAGGTCATTCGCCGGCTGGAGGGCGACAGCGGTCGGATCGGCAAGGTGC
TGGAAGTCATCCGCGGCATCGCCGACCAGACCAACCTGCTGGCGCTCAATGCCGCCATCGAGGCGGCCCGTGCTGGCGAC
GCCGGCCGCGGTTTTACCGTGGTGGCCGACGAGGTGCGCACCCTGGCCCAGCGCACCGCCGAATCCACCGCCGAGATCCA
CCAGATCATCGATACCGTGCAGACCGGCGCAAGCAATGCGGTGCGTGCCATCGAGAGCGGCCAGGTACGCAGCGAACAGG
GGGTCGGCCAGGTGACCGAGGCCGGACTGATGCTGCAACGCATCACCGAGGCCGTGGAGGCGATCCGCGACATGAACCGG
CAGATCGCAACCGCGGCCGAGGAACAGACAGCGGTGGCCGAGGACATCTCGCGCAACCTCACCGAGATCACCTCCATCGC
CACCATCAACCAGCAGAACGTCGAACGCACCGAAACCGCCAGTCAGAACCTGCACGGCCTGTCGGCGCAGCTCACCGAGG
TCACCCGCCGCCTCGCTGGCTGA

Upstream 100 bases:

>100_bases
TCTGCGCATCGTCTAGCTCAAGAAACACGTCACCCGGCCGATGTGCTGGGCAACGGCAGGGATGCTCATTGACGTTTTCT
CAAACGACGAGACCTTGCCC

Downstream 100 bases:

>100_bases
CGATCAGCGGGGCGGCCCGACAGCCTGTCGCCCGCCCCGCCTTTCGGTGGCCCTGCGCCCCCTCTCCCCCTTTACTTGCT
TCCGATTCGGGGCTAAGTTC

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 540; Mature: 540

Protein sequence:

>540_residues
MLQKSLRAQILALIGGSLLLTLLIALGCIRMLSSDIDQFQTLLDGPLAELQLIDEANLEFKVQVQEWKNVLLRGKQLENR
NRYWSQFEAQEAKVQKVLGDLLVLSADEPELAGQIERLRNEHRTLGGAYRKGLDAFIAAGSDPLAGDAAVAGIDRATSAQ
LSELVKQLHAAARQRSEAIQADAEATALLGPVIMILAGVVVALLSLWLVNRRIIEPIRTLIEHIARLSQGKFAERVDASR
ADELGRLAVAANVLRDFLADTFTRLQQSTSNLDSASGELNAIARLMADGAREQFSRTDQVATAMHEMSATAQEVSRHAAE
AAQAADAADHAAQQGEAVMRGTIASITDMSSEIASTAEVIRRLEGDSGRIGKVLEVIRGIADQTNLLALNAAIEAARAGD
AGRGFTVVADEVRTLAQRTAESTAEIHQIIDTVQTGASNAVRAIESGQVRSEQGVGQVTEAGLMLQRITEAVEAIRDMNR
QIATAAEEQTAVAEDISRNLTEITSIATINQQNVERTETASQNLHGLSAQLTEVTRRLAG

Sequences:

>Translated_540_residues
MLQKSLRAQILALIGGSLLLTLLIALGCIRMLSSDIDQFQTLLDGPLAELQLIDEANLEFKVQVQEWKNVLLRGKQLENR
NRYWSQFEAQEAKVQKVLGDLLVLSADEPELAGQIERLRNEHRTLGGAYRKGLDAFIAAGSDPLAGDAAVAGIDRATSAQ
LSELVKQLHAAARQRSEAIQADAEATALLGPVIMILAGVVVALLSLWLVNRRIIEPIRTLIEHIARLSQGKFAERVDASR
ADELGRLAVAANVLRDFLADTFTRLQQSTSNLDSASGELNAIARLMADGAREQFSRTDQVATAMHEMSATAQEVSRHAAE
AAQAADAADHAAQQGEAVMRGTIASITDMSSEIASTAEVIRRLEGDSGRIGKVLEVIRGIADQTNLLALNAAIEAARAGD
AGRGFTVVADEVRTLAQRTAESTAEIHQIIDTVQTGASNAVRAIESGQVRSEQGVGQVTEAGLMLQRITEAVEAIRDMNR
QIATAAEEQTAVAEDISRNLTEITSIATINQQNVERTETASQNLHGLSAQLTEVTRRLAG
>Mature_540_residues
MLQKSLRAQILALIGGSLLLTLLIALGCIRMLSSDIDQFQTLLDGPLAELQLIDEANLEFKVQVQEWKNVLLRGKQLENR
NRYWSQFEAQEAKVQKVLGDLLVLSADEPELAGQIERLRNEHRTLGGAYRKGLDAFIAAGSDPLAGDAAVAGIDRATSAQ
LSELVKQLHAAARQRSEAIQADAEATALLGPVIMILAGVVVALLSLWLVNRRIIEPIRTLIEHIARLSQGKFAERVDASR
ADELGRLAVAANVLRDFLADTFTRLQQSTSNLDSASGELNAIARLMADGAREQFSRTDQVATAMHEMSATAQEVSRHAAE
AAQAADAADHAAQQGEAVMRGTIASITDMSSEIASTAEVIRRLEGDSGRIGKVLEVIRGIADQTNLLALNAAIEAARAGD
AGRGFTVVADEVRTLAQRTAESTAEIHQIIDTVQTGASNAVRAIESGQVRSEQGVGQVTEAGLMLQRITEAVEAIRDMNR
QIATAAEEQTAVAEDISRNLTEITSIATINQQNVERTETASQNLHGLSAQLTEVTRRLAG

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=308, Percent_Identity=30.8441558441558, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1787690, Length=348, Percent_Identity=29.5977011494253, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI2367378, Length=304, Percent_Identity=28.9473684210526, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI1788194, Length=361, Percent_Identity=27.9778393351801, Blast_Score=116, Evalue=4e-27,
Organism=Escherichia coli, GI1789453, Length=339, Percent_Identity=27.4336283185841, Blast_Score=103, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 58028; Mature: 58028

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQKSLRAQILALIGGSLLLTLLIALGCIRMLSSDIDQFQTLLDGPLAELQLIDEANLEF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEE
KVQVQEWKNVLLRGKQLENRNRYWSQFEAQEAKVQKVLGDLLVLSADEPELAGQIERLRN
EEEHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
EHRTLGGAYRKGLDAFIAAGSDPLAGDAAVAGIDRATSAQLSELVKQLHAAARQRSEAIQ
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ADAEATALLGPVIMILAGVVVALLSLWLVNRRIIEPIRTLIEHIARLSQGKFAERVDASR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
ADELGRLAVAANVLRDFLADTFTRLQQSTSNLDSASGELNAIARLMADGAREQFSRTDQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ATAMHEMSATAQEVSRHAAEAAQAADAADHAAQQGEAVMRGTIASITDMSSEIASTAEVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHH
RRLEGDSGRIGKVLEVIRGIADQTNLLALNAAIEAARAGDAGRGFTVVADEVRTLAQRTA
HHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
ESTAEIHQIIDTVQTGASNAVRAIESGQVRSEQGVGQVTEAGLMLQRITEAVEAIRDMNR
HHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QIATAAEEQTAVAEDISRNLTEITSIATINQQNVERTETASQNLHGLSAQLTEVTRRLAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLQKSLRAQILALIGGSLLLTLLIALGCIRMLSSDIDQFQTLLDGPLAELQLIDEANLEF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEE
KVQVQEWKNVLLRGKQLENRNRYWSQFEAQEAKVQKVLGDLLVLSADEPELAGQIERLRN
EEEHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
EHRTLGGAYRKGLDAFIAAGSDPLAGDAAVAGIDRATSAQLSELVKQLHAAARQRSEAIQ
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ADAEATALLGPVIMILAGVVVALLSLWLVNRRIIEPIRTLIEHIARLSQGKFAERVDASR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
ADELGRLAVAANVLRDFLADTFTRLQQSTSNLDSASGELNAIARLMADGAREQFSRTDQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ATAMHEMSATAQEVSRHAAEAAQAADAADHAAQQGEAVMRGTIASITDMSSEIASTAEVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHH
RRLEGDSGRIGKVLEVIRGIADQTNLLALNAAIEAARAGDAGRGFTVVADEVRTLAQRTA
HHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
ESTAEIHQIIDTVQTGASNAVRAIESGQVRSEQGVGQVTEAGLMLQRITEAVEAIRDMNR
HHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QIATAAEEQTAVAEDISRNLTEITSIATINQQNVERTETASQNLHGLSAQLTEVTRRLAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]