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The map label for this gene is pncB1 [H]

Identifier: 146283452

GI number: 146283452

Start: 3362462

End: 3363661

Strand: Direct

Name: pncB1 [H]

Synonym: PST_3125

Alternate gene names: 146283452

Gene position: 3362462-3363661 (Clockwise)

Preceding gene: 146283451

Following gene: 146283454

Centisome position: 73.62

GC content: 63.92

Gene sequence:

>1200_bases
ATGAGCAGCGCATTTTCGGACCGCATCATCCAGAGCCTGCTGGATACCGACTTCTACAAGCTCACCATGATGCAGGCGGT
CCTGCATCACTACCCTAATGCGGAAGTGGAATGGGCCTTTCGCAGCCGCTCCGGCGAAGACCTGAGCCCTTACCTGAGCG
AGATCCGCCACCAGATCGAAGCGCTGGCCGAGCTGCAGATGTCCGCCGAGGAATTGGCCTTCCTCGAGCGCGTCCCCTAT
ATGCAGCCCGACTTCATCCGCTTTCTCGGGCTGTTCCGCTTCGACCTCCGCTACCTGCGGGTGGATGTCGAGGACGGCGA
GCTGGTGATGTATCTGCGCGGGCCCTGGCTGCATGTGATCCTGTTCGAAGTACCGCTGCTGGCCATCGTCAGCGAGGTGC
GCAACCGCGCGCGCTATGCGCAGGTGACGCTGGAACAGGCGGGCGCCAGGCTGGACGAAAAGTTCGCCTGGCTGCGCAGG
CAGGCGACTGCCGAGGAGCTGGCCAGCTTCACCCTGGCTGACTTCGGCACCCGGCGACGATTCTCCTTCGCGGTTCAGGC
CATGGTGGTCGAGCGCCTGCGCTGCGACTTTCCCGGCCGTTTCGTCGGCACCAGCAACGTGCATCTGGCCCGCACGCTGG
ACGTGAAACCCATGGGCACCATGGCCCACGAATGGGTCATGGCGCACCAGCAGCTCGGCCCGCGCCTCATCGACAGTCAG
GTCGCGGCGCTCGACTGCTGGGTTCGCGAATACCGTGGCGCACTGGGCATCGCGCTGACCGACTGCATCACCATGGATGC
CTTCCTGCGCGACTTCGATCTGTACTTCGCCAAGCTGTTCGATGGCCTGCGCCACGACTCGGGCGATCCCTTGGAATGGG
CGGAGAAAGCCATCGCACACTACCGGCGCCTCGGCATCGATCCGAAAAGCCGTCAGCTGATCTTTTCCGACGGTCTGGAT
TTCGCCAAGGCACTGCACATCCACCGCGCCCTGATCGACCGCAGCAGACCCAGCTTCGGCATAGGCACCGGGCTCACCTG
CGACATTCCGGGAGTGGAGCCGACCAACATGGTGATCAAGATGACCGCCTGCAACGGCCAGCCGGTGGCAAAGATCTCCG
ACTCGCCGGGCAAGACCATGTGCCGCGACGAAGCCTTCGTCAGCTACCTGCGCCACGTGTTCGGCGTCGCTGCCGGCTGA

Upstream 100 bases:

>100_bases
AATGGCAGCACCCGCTCGGCAACACGCCAAAGGCCTTCGGGCAGCGCCTTGCTCGCCATTTGCCGCTACCATCACCCGAT
GTCCAGAACGGAACGACCCG

Downstream 100 bases:

>100_bases
CCCGGACGCGCCGCACGCTACCCTGCGGCTAGCCGCTCAGCGCGAGCGACCCCTGCTGCAGCACCGCATCCGGCTCCATT
GCGCAGAGCCGATTGCGCCC

Product: nicotinate phosphoribosyltransferase

Products: NA

Alternate protein names: NAPRTase [H]

Number of amino acids: Translated: 399; Mature: 398

Protein sequence:

>399_residues
MSSAFSDRIIQSLLDTDFYKLTMMQAVLHHYPNAEVEWAFRSRSGEDLSPYLSEIRHQIEALAELQMSAEELAFLERVPY
MQPDFIRFLGLFRFDLRYLRVDVEDGELVMYLRGPWLHVILFEVPLLAIVSEVRNRARYAQVTLEQAGARLDEKFAWLRR
QATAEELASFTLADFGTRRRFSFAVQAMVVERLRCDFPGRFVGTSNVHLARTLDVKPMGTMAHEWVMAHQQLGPRLIDSQ
VAALDCWVREYRGALGIALTDCITMDAFLRDFDLYFAKLFDGLRHDSGDPLEWAEKAIAHYRRLGIDPKSRQLIFSDGLD
FAKALHIHRALIDRSRPSFGIGTGLTCDIPGVEPTNMVIKMTACNGQPVAKISDSPGKTMCRDEAFVSYLRHVFGVAAG

Sequences:

>Translated_399_residues
MSSAFSDRIIQSLLDTDFYKLTMMQAVLHHYPNAEVEWAFRSRSGEDLSPYLSEIRHQIEALAELQMSAEELAFLERVPY
MQPDFIRFLGLFRFDLRYLRVDVEDGELVMYLRGPWLHVILFEVPLLAIVSEVRNRARYAQVTLEQAGARLDEKFAWLRR
QATAEELASFTLADFGTRRRFSFAVQAMVVERLRCDFPGRFVGTSNVHLARTLDVKPMGTMAHEWVMAHQQLGPRLIDSQ
VAALDCWVREYRGALGIALTDCITMDAFLRDFDLYFAKLFDGLRHDSGDPLEWAEKAIAHYRRLGIDPKSRQLIFSDGLD
FAKALHIHRALIDRSRPSFGIGTGLTCDIPGVEPTNMVIKMTACNGQPVAKISDSPGKTMCRDEAFVSYLRHVFGVAAG
>Mature_398_residues
SSAFSDRIIQSLLDTDFYKLTMMQAVLHHYPNAEVEWAFRSRSGEDLSPYLSEIRHQIEALAELQMSAEELAFLERVPYM
QPDFIRFLGLFRFDLRYLRVDVEDGELVMYLRGPWLHVILFEVPLLAIVSEVRNRARYAQVTLEQAGARLDEKFAWLRRQ
ATAEELASFTLADFGTRRRFSFAVQAMVVERLRCDFPGRFVGTSNVHLARTLDVKPMGTMAHEWVMAHQQLGPRLIDSQV
AALDCWVREYRGALGIALTDCITMDAFLRDFDLYFAKLFDGLRHDSGDPLEWAEKAIAHYRRLGIDPKSRQLIFSDGLDF
AKALHIHRALIDRSRPSFGIGTGLTCDIPGVEPTNMVIKMTACNGQPVAKISDSPGKTMCRDEAFVSYLRHVFGVAAG

Specific function: NAD biosynthesis; nicotinamide to NaMN; second step. [C]

COG id: COG1488

COG function: function code H; Nicotinic acid phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAPRTase family [H]

Homologues:

Organism=Escherichia coli, GI1787162, Length=394, Percent_Identity=51.5228426395939, Blast_Score=405, Evalue=1e-114,
Organism=Saccharomyces cerevisiae, GI6324783, Length=422, Percent_Identity=31.5165876777251, Blast_Score=199, Evalue=6e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006406
- InterPro:   IPR015977
- InterPro:   IPR007229
- InterPro:   IPR002638 [H]

Pfam domain/function: PF04095 NAPRTase [H]

EC number: =2.4.2.11 [H]

Molecular weight: Translated: 45421; Mature: 45290

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSAFSDRIIQSLLDTDFYKLTMMQAVLHHYPNAEVEWAFRSRSGEDLSPYLSEIRHQIE
CCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHH
ALAELQMSAEELAFLERVPYMQPDFIRFLGLFRFDLRYLRVDVEDGELVMYLRGPWLHVI
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCEEHEEEEECCCCEEEEECCCHHHHH
LFEVPLLAIVSEVRNRARYAQVTLEQAGARLDEKFAWLRRQATAEELASFTLADFGTRRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
FSFAVQAMVVERLRCDFPGRFVGTSNVHLARTLDVKPMGTMAHEWVMAHQQLGPRLIDSQ
HHHHHHHHHHHHHHCCCCCCEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCHHHHHH
VAALDCWVREYRGALGIALTDCITMDAFLRDFDLYFAKLFDGLRHDSGDPLEWAEKAIAH
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
YRRLGIDPKSRQLIFSDGLDFAKALHIHRALIDRSRPSFGIGTGLTCDIPGVEPTNMVIK
HHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCCCEEEE
MTACNGQPVAKISDSPGKTMCRDEAFVSYLRHVFGVAAG
EEECCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SSAFSDRIIQSLLDTDFYKLTMMQAVLHHYPNAEVEWAFRSRSGEDLSPYLSEIRHQIE
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHH
ALAELQMSAEELAFLERVPYMQPDFIRFLGLFRFDLRYLRVDVEDGELVMYLRGPWLHVI
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCEEHEEEEECCCCEEEEECCCHHHHH
LFEVPLLAIVSEVRNRARYAQVTLEQAGARLDEKFAWLRRQATAEELASFTLADFGTRRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
FSFAVQAMVVERLRCDFPGRFVGTSNVHLARTLDVKPMGTMAHEWVMAHQQLGPRLIDSQ
HHHHHHHHHHHHHHCCCCCCEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCHHHHHH
VAALDCWVREYRGALGIALTDCITMDAFLRDFDLYFAKLFDGLRHDSGDPLEWAEKAIAH
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
YRRLGIDPKSRQLIFSDGLDFAKALHIHRALIDRSRPSFGIGTGLTCDIPGVEPTNMVIK
HHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCCCEEEE
MTACNGQPVAKISDSPGKTMCRDEAFVSYLRHVFGVAAG
EEECCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA