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The map label for this gene is steT [H]

Identifier: 146283353

GI number: 146283353

Start: 3254918

End: 3256267

Strand: Direct

Name: steT [H]

Synonym: PST_3023

Alternate gene names: 146283353

Gene position: 3254918-3256267 (Clockwise)

Preceding gene: 146283352

Following gene: 146283356

Centisome position: 71.26

GC content: 68.74

Gene sequence:

>1350_bases
ATGAGTAGCCAGATGCGCTCGCGGCACAGCGGCGACCTCTCGGTGATCGATGGCGTAGCCGTGCTGGTCGGCGTCGTGGT
GGGCGTCGGCATCTTCGGCTTCCCGCCCCTGGTCGCCCAGCATGCCGACAGCGGGACGCTGTATATCGCCCTCTGGCTGG
CCGGAGGCGCGCTGATGCTGGTCGGCGCGCTGTGCTACGCGGAGCTGGGCGCGAGCTTCCCCGACGAGGGCGGCGAGTAC
CACTACCTGCGGCTGGCCTGGGGTCGCCGTTTCGGCCTGATGTTCGCATGGGCCCGCGGTACCGTGATCCAGACCGGCGC
CATCGCCGCGGTGGCCTTCATCTACGGCGACTACGCGCAACGGCTGATGCCCCTGGGCGACCACGGCGGCACGCTGCACG
CCCTGCTCTCAGTGGCATTGCTGACCACGCTCAACGTGTGCGGCACGCGCGAGTCCAAACGCGTCCAGATCGCCCTGAGC
AGCCTAACCCTAGTCGCCGTCATCGGCGTGATGCTGGCCGGCCTGCTTTCCAGCGGCCCCAGCTCGCCGGCCGCGATCGA
GCCGCGCGACGGAGGCCTCGGCATGCTGGGCATGGGCATGGTCTTCGTGCTGCTGACCTACGGAGGCTGGAACGAAACCG
CCTACCTGTCGGGCGAGCTGCGCAACCCGGCGCGCAACATGGGCCGCGTACTGCTGCTCGGCACGCTGCTGGTGACCACC
CTCTATTTGCTGACCAACCTGGCACTGCTGCAGATATTCGGTCTGCAGGCGCTCAGCCAGTCGGACGCGATCGGTGCCGA
TCTGATGGAGATCGTCGCCGGTAGCTGGGCGGCCCAGGGGCTGAGCCTGCTGATCTGCTTTACCGCGCTCAGCACGCTCA
ACGCGACGATCCTCACCGGAGCACGGGTGTATTACGCGCTGGGCCGGGACGTGCCGCGGCTGCATCGGCTCGCGGCGTGG
AACGAGCGTGGCTCGACGCCCGTACGGGCATTGCTGGTACAGGCGACGATCACCCTGCTGCTGATCCTGTTCGGCGCGCT
GAGCCAGAGCGGCGTGCAGGCGATGGTCGCCTACACCGCGCCGGTATTCTGGTTCTTCATGTGCATGACGGCGCTGTCGC
TGCTGCGACTGCGCCGGCTGGAGGCCTCGGCGCCACGGCCATTCCGCGTGCCCTGGTACCCCTGGCTACCGCTGCTGTTC
GCCAGCAGCTGCCTGGGCCTGTTCGTCTCCAGCACGCTCTACGCGGGACCGGGCGCGCTGCTGGGGCTGCTGGTCCTTGC
CTTCGGCCTGCCGCTTCTACTGGTGCGCAGCCCGGCTGCAGTGAGCGCAACCTCGGGCGTCGAGCCCTAG

Upstream 100 bases:

>100_bases
TGGGCGGCATGGACTACGTGGGCAAGGTGGAAGGCGACCGTATCAACCCGCTGCAAGGTGAAGGAGTCGCCTCCGGCTGG
AGCGCGCGGCGTAGCTGAAC

Downstream 100 bases:

>100_bases
AGCTTCAGCTCGAACTCGTCGCCGTCGTGGTACGCCGGGAAGCGCTCGCGGAACGCCGCCAGGTCGCGGGCGCGCAGGGA
ACAGCGGAAAACGCCATCGC

Product: amino acid transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MSSQMRSRHSGDLSVIDGVAVLVGVVVGVGIFGFPPLVAQHADSGTLYIALWLAGGALMLVGALCYAELGASFPDEGGEY
HYLRLAWGRRFGLMFAWARGTVIQTGAIAAVAFIYGDYAQRLMPLGDHGGTLHALLSVALLTTLNVCGTRESKRVQIALS
SLTLVAVIGVMLAGLLSSGPSSPAAIEPRDGGLGMLGMGMVFVLLTYGGWNETAYLSGELRNPARNMGRVLLLGTLLVTT
LYLLTNLALLQIFGLQALSQSDAIGADLMEIVAGSWAAQGLSLLICFTALSTLNATILTGARVYYALGRDVPRLHRLAAW
NERGSTPVRALLVQATITLLLILFGALSQSGVQAMVAYTAPVFWFFMCMTALSLLRLRRLEASAPRPFRVPWYPWLPLLF
ASSCLGLFVSSTLYAGPGALLGLLVLAFGLPLLLVRSPAAVSATSGVEP

Sequences:

>Translated_449_residues
MSSQMRSRHSGDLSVIDGVAVLVGVVVGVGIFGFPPLVAQHADSGTLYIALWLAGGALMLVGALCYAELGASFPDEGGEY
HYLRLAWGRRFGLMFAWARGTVIQTGAIAAVAFIYGDYAQRLMPLGDHGGTLHALLSVALLTTLNVCGTRESKRVQIALS
SLTLVAVIGVMLAGLLSSGPSSPAAIEPRDGGLGMLGMGMVFVLLTYGGWNETAYLSGELRNPARNMGRVLLLGTLLVTT
LYLLTNLALLQIFGLQALSQSDAIGADLMEIVAGSWAAQGLSLLICFTALSTLNATILTGARVYYALGRDVPRLHRLAAW
NERGSTPVRALLVQATITLLLILFGALSQSGVQAMVAYTAPVFWFFMCMTALSLLRLRRLEASAPRPFRVPWYPWLPLLF
ASSCLGLFVSSTLYAGPGALLGLLVLAFGLPLLLVRSPAAVSATSGVEP
>Mature_448_residues
SSQMRSRHSGDLSVIDGVAVLVGVVVGVGIFGFPPLVAQHADSGTLYIALWLAGGALMLVGALCYAELGASFPDEGGEYH
YLRLAWGRRFGLMFAWARGTVIQTGAIAAVAFIYGDYAQRLMPLGDHGGTLHALLSVALLTTLNVCGTRESKRVQIALSS
LTLVAVIGVMLAGLLSSGPSSPAAIEPRDGGLGMLGMGMVFVLLTYGGWNETAYLSGELRNPARNMGRVLLLGTLLVTTL
YLLTNLALLQIFGLQALSQSDAIGADLMEIVAGSWAAQGLSLLICFTALSTLNATILTGARVYYALGRDVPRLHRLAAWN
ERGSTPVRALLVQATITLLLILFGALSQSGVQAMVAYTAPVFWFFMCMTALSLLRLRRLEASAPRPFRVPWYPWLPLLFA
SSCLGLFVSSTLYAGPGALLGLLVLAFGLPLLLVRSPAAVSATSGVEP

Specific function: Exhibits an obligate exchange activity for serine, threonine and aromatic amino acids [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family [H]

Homologues:

Organism=Homo sapiens, GI115648063, Length=433, Percent_Identity=27.2517321016166, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI115648022, Length=433, Percent_Identity=27.2517321016166, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI186910308, Length=446, Percent_Identity=26.0089686098655, Blast_Score=155, Evalue=6e-38,
Organism=Homo sapiens, GI186910306, Length=446, Percent_Identity=26.0089686098655, Blast_Score=155, Evalue=6e-38,
Organism=Homo sapiens, GI186910304, Length=446, Percent_Identity=26.0089686098655, Blast_Score=155, Evalue=6e-38,
Organism=Homo sapiens, GI187423910, Length=390, Percent_Identity=28.4615384615385, Blast_Score=155, Evalue=8e-38,
Organism=Homo sapiens, GI7657591, Length=390, Percent_Identity=28.4615384615385, Blast_Score=155, Evalue=8e-38,
Organism=Homo sapiens, GI33286428, Length=403, Percent_Identity=27.0471464019851, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI71979932, Length=433, Percent_Identity=27.2517321016166, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI7657683, Length=408, Percent_Identity=23.7745098039216, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI9790235, Length=324, Percent_Identity=26.2345679012346, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI33286430, Length=202, Percent_Identity=24.7524752475248, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI71999149, Length=392, Percent_Identity=23.469387755102, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI87082250, Length=439, Percent_Identity=24.1457858769932, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1786694, Length=390, Percent_Identity=24.8717948717949, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790584, Length=373, Percent_Identity=25.4691689008043, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17540018, Length=436, Percent_Identity=25.6880733944954, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17568033, Length=451, Percent_Identity=24.8337028824834, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI32566699, Length=347, Percent_Identity=25.6484149855908, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI71993915, Length=401, Percent_Identity=26.1845386533666, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI71995382, Length=393, Percent_Identity=25.9541984732824, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI71995388, Length=390, Percent_Identity=26.1538461538462, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI71982608, Length=448, Percent_Identity=23.8839285714286, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI71982612, Length=448, Percent_Identity=23.8839285714286, Blast_Score=108, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI71990446, Length=429, Percent_Identity=22.1445221445221, Blast_Score=92, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI193208714, Length=425, Percent_Identity=22.8235294117647, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI32566695, Length=425, Percent_Identity=22.8235294117647, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17532491, Length=366, Percent_Identity=21.8579234972678, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6321751, Length=356, Percent_Identity=21.6292134831461, Blast_Score=70, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6321492, Length=431, Percent_Identity=21.5777262180974, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI45550968, Length=433, Percent_Identity=28.6374133949192, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI19921172, Length=433, Percent_Identity=28.6374133949192, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI21357367, Length=448, Percent_Identity=24.5535714285714, Blast_Score=145, Evalue=7e-35,
Organism=Drosophila melanogaster, GI221331183, Length=444, Percent_Identity=26.3513513513513, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI17647653, Length=444, Percent_Identity=26.3513513513513, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24664379, Length=444, Percent_Identity=26.3513513513513, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24651635, Length=441, Percent_Identity=26.0770975056689, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24651633, Length=441, Percent_Identity=26.0770975056689, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24641993, Length=398, Percent_Identity=26.3819095477387, Blast_Score=118, Evalue=9e-27,
Organism=Drosophila melanogaster, GI24641995, Length=398, Percent_Identity=26.3819095477387, Blast_Score=117, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 47474; Mature: 47342

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSQMRSRHSGDLSVIDGVAVLVGVVVGVGIFGFPPLVAQHADSGTLYIALWLAGGALML
CCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCEEEEEHHHHCCHHHH
VGALCYAELGASFPDEGGEYHYLRLAWGRRFGLMFAWARGTVIQTGAIAAVAFIYGDYAQ
HHHHHHHHHCCCCCCCCCCEEEEEEECCCHHHHEEEECCCCEEEHHHHHHHHHHHHHHHH
RLMPLGDHGGTLHALLSVALLTTLNVCGTRESKRVQIALSSLTLVAVIGVMLAGLLSSGP
HHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCC
SSPAAIEPRDGGLGMLGMGMVFVLLTYGGWNETAYLSGELRNPARNMGRVLLLGTLLVTT
CCCCEECCCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHH
LYLLTNLALLQIFGLQALSQSDAIGADLMEIVAGSWAAQGLSLLICFTALSTLNATILTG
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARVYYALGRDVPRLHRLAAWNERGSTPVRALLVQATITLLLILFGALSQSGVQAMVAYTA
HHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
PVFWFFMCMTALSLLRLRRLEASAPRPFRVPWYPWLPLLFASSCLGLFVSSTLYAGPGAL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHH
LGLLVLAFGLPLLLVRSPAAVSATSGVEP
HHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
SSQMRSRHSGDLSVIDGVAVLVGVVVGVGIFGFPPLVAQHADSGTLYIALWLAGGALML
CCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCEEEEEHHHHCCHHHH
VGALCYAELGASFPDEGGEYHYLRLAWGRRFGLMFAWARGTVIQTGAIAAVAFIYGDYAQ
HHHHHHHHHCCCCCCCCCCEEEEEEECCCHHHHEEEECCCCEEEHHHHHHHHHHHHHHHH
RLMPLGDHGGTLHALLSVALLTTLNVCGTRESKRVQIALSSLTLVAVIGVMLAGLLSSGP
HHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCC
SSPAAIEPRDGGLGMLGMGMVFVLLTYGGWNETAYLSGELRNPARNMGRVLLLGTLLVTT
CCCCEECCCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHH
LYLLTNLALLQIFGLQALSQSDAIGADLMEIVAGSWAAQGLSLLICFTALSTLNATILTG
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARVYYALGRDVPRLHRLAAWNERGSTPVRALLVQATITLLLILFGALSQSGVQAMVAYTA
HHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
PVFWFFMCMTALSLLRLRRLEASAPRPFRVPWYPWLPLLFASSCLGLFVSSTLYAGPGAL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHH
LGLLVLAFGLPLLLVRSPAAVSATSGVEP
HHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]