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The map label for this gene is trpB [H]

Identifier: 146283230

GI number: 146283230

Start: 3117256

End: 3118467

Strand: Direct

Name: trpB [H]

Synonym: PST_2895

Alternate gene names: 146283230

Gene position: 3117256-3118467 (Clockwise)

Preceding gene: 146283227

Following gene: 146283231

Centisome position: 68.25

GC content: 64.85

Gene sequence:

>1212_bases
ATGACCTCATACCGCAACGGCCCTGACGCCAAGGGCCTGTTCGGCCACTTCGGTGGTCAGTACGTCGCCGAAACGCTGAT
GCCGCTCATCCACGAGCTGGCCGCCGAGTACGAAAAAGCCAAGGCCGACCCCGAGTTCGCCAAGGAGCTCGCCTACTTCC
AGCGCGACTACGTGGGCCGCCCCTCGCCGCTGTACTTCGCCGAGCGCCTGACCGAACACTGCGGCGGCGCGAAGATCTAC
CTCAAGCGCGAAGAGCTCAACCACACCGGCGCGCACAAGATCAACAACTGCATCGGCCAGATCCTGCTGGCCAAGCGCAT
GGGCAAGCAGCGCATCATCGCCGAGACCGGCGCCGGCATGCACGGCGTGGCCACTGCCACCGTGGCCGCGCGCTTCGGCA
TGCAGTGCGTGATCTACATGGGCACCACCGACATCGACCGCCAGCAGGCCAACGTCTTCCGCATGAAGCTCCTGGGCGCC
GAAGTGATTCCGGTCACCGCCGGCACCGGCACCCTGAAGGACGCGATGAACGAAGCCCTGCGCGACTGGGTGACCAACGT
CCACAACACCTTCTACCTGATCGGCACCGTCGCCGGACCGCACCCCTACCCCGCCATGGTCCGCGACTTCCAGGCCGTGA
TCGGCAAGGAAACCCGCGAGCAGATGATGGAAAAGGAAGGTCGCCTGCCCGACTCGCTGGTGGCCTGTATCGGTGGCGGC
TCCAATGCCATGGGCCTGTTCCATCCGTTCCTGGATGACGCCAGTGTGAAGATCATCGGCGTCGAGGCGGCCGGGCACGG
TATCGAGACCGGCCAGCACGCGGCGAGCCTGAACGGCGGCGTACCCGGCGTACTGCACGGCAACCGCACCTTCCTCCTGC
AGAACGAGGATGGCCAGATCATCGACGCCCACTCGATCTCCGCCGGCCTGGACTACCCCGGCATCGGCCCGGAACACGCC
TGGCTGCACGACATCGGCCGCGTCGAGTACACCTCGATCACCGACAAGGAAGCGCTCAAGGCTTTCCATACCTGCTGCCG
CCTGGAAGGCATCATCCCGGCGCTGGAGTCCTCCCACGCGCTGGCTGAAGTATTCAAGCGCGCGCCTGGTCTGCCGAAGG
ATCACCTGATGGTGGTCAACCTCTCCGGCCGCGGCGACAAGGACATGCAGACCGTCATGCACCACTACGACGAACAGGAA
GAACATATATGA

Upstream 100 bases:

>100_bases
CGTCGATCTTATCGCTTTTATCCGGGCGGCCATAGCCGTACCCTGACGCCATCGCATCTGCCGGCCCGCGCTCGGCAGCC
CGCCTACACAGGAGTCCGAC

Downstream 100 bases:

>100_bases
GCCGCCTGCTGACGCGCTTCGACGAGCTGAAACAACAGAACCGCGCCGCACTGGTGACCTTCATCACCGCCGGCGATCCG
GACTACGCCACCTCGCTGCA

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MTSYRNGPDAKGLFGHFGGQYVAETLMPLIHELAAEYEKAKADPEFAKELAYFQRDYVGRPSPLYFAERLTEHCGGAKIY
LKREELNHTGAHKINNCIGQILLAKRMGKQRIIAETGAGMHGVATATVAARFGMQCVIYMGTTDIDRQQANVFRMKLLGA
EVIPVTAGTGTLKDAMNEALRDWVTNVHNTFYLIGTVAGPHPYPAMVRDFQAVIGKETREQMMEKEGRLPDSLVACIGGG
SNAMGLFHPFLDDASVKIIGVEAAGHGIETGQHAASLNGGVPGVLHGNRTFLLQNEDGQIIDAHSISAGLDYPGIGPEHA
WLHDIGRVEYTSITDKEALKAFHTCCRLEGIIPALESSHALAEVFKRAPGLPKDHLMVVNLSGRGDKDMQTVMHHYDEQE
EHI

Sequences:

>Translated_403_residues
MTSYRNGPDAKGLFGHFGGQYVAETLMPLIHELAAEYEKAKADPEFAKELAYFQRDYVGRPSPLYFAERLTEHCGGAKIY
LKREELNHTGAHKINNCIGQILLAKRMGKQRIIAETGAGMHGVATATVAARFGMQCVIYMGTTDIDRQQANVFRMKLLGA
EVIPVTAGTGTLKDAMNEALRDWVTNVHNTFYLIGTVAGPHPYPAMVRDFQAVIGKETREQMMEKEGRLPDSLVACIGGG
SNAMGLFHPFLDDASVKIIGVEAAGHGIETGQHAASLNGGVPGVLHGNRTFLLQNEDGQIIDAHSISAGLDYPGIGPEHA
WLHDIGRVEYTSITDKEALKAFHTCCRLEGIIPALESSHALAEVFKRAPGLPKDHLMVVNLSGRGDKDMQTVMHHYDEQE
EHI
>Mature_402_residues
TSYRNGPDAKGLFGHFGGQYVAETLMPLIHELAAEYEKAKADPEFAKELAYFQRDYVGRPSPLYFAERLTEHCGGAKIYL
KREELNHTGAHKINNCIGQILLAKRMGKQRIIAETGAGMHGVATATVAARFGMQCVIYMGTTDIDRQQANVFRMKLLGAE
VIPVTAGTGTLKDAMNEALRDWVTNVHNTFYLIGTVAGPHPYPAMVRDFQAVIGKETREQMMEKEGRLPDSLVACIGGGS
NAMGLFHPFLDDASVKIIGVEAAGHGIETGQHAASLNGGVPGVLHGNRTFLLQNEDGQIIDAHSISAGLDYPGIGPEHAW
LHDIGRVEYTSITDKEALKAFHTCCRLEGIIPALESSHALAEVFKRAPGLPKDHLMVVNLSGRGDKDMQTVMHHYDEQEE
HI

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=380, Percent_Identity=55.7894736842105, Blast_Score=440, Evalue=1e-125,
Organism=Saccharomyces cerevisiae, GI6321412, Length=380, Percent_Identity=56.578947368421, Blast_Score=461, Evalue=1e-130,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 44025; Mature: 43894

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSYRNGPDAKGLFGHFGGQYVAETLMPLIHELAAEYEKAKADPEFAKELAYFQRDYVGR
CCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
PSPLYFAERLTEHCGGAKIYLKREELNHTGAHKINNCIGQILLAKRMGKQRIIAETGAGM
CCHHHHHHHHHHHCCCCEEEEEHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCC
HGVATATVAARFGMQCVIYMGTTDIDRQQANVFRMKLLGAEVIPVTAGTGTLKDAMNEAL
CHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHH
RDWVTNVHNTFYLIGTVAGPHPYPAMVRDFQAVIGKETREQMMEKEGRLPDSLVACIGGG
HHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHCCC
SNAMGLFHPFLDDASVKIIGVEAAGHGIETGQHAASLNGGVPGVLHGNRTFLLQNEDGQI
CCCCHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHCCCCCCEEEECCEEEEEECCCCCE
IDAHSISAGLDYPGIGPEHAWLHDIGRVEYTSITDKEALKAFHTCCRLEGIIPALESSHA
EEECCCCCCCCCCCCCCCHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHCHHHHCCHHH
LAEVFKRAPGLPKDHLMVVNLSGRGDKDMQTVMHHYDEQEEHI
HHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHCCHHHCCC
>Mature Secondary Structure 
TSYRNGPDAKGLFGHFGGQYVAETLMPLIHELAAEYEKAKADPEFAKELAYFQRDYVGR
CCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
PSPLYFAERLTEHCGGAKIYLKREELNHTGAHKINNCIGQILLAKRMGKQRIIAETGAGM
CCHHHHHHHHHHHCCCCEEEEEHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCC
HGVATATVAARFGMQCVIYMGTTDIDRQQANVFRMKLLGAEVIPVTAGTGTLKDAMNEAL
CHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHH
RDWVTNVHNTFYLIGTVAGPHPYPAMVRDFQAVIGKETREQMMEKEGRLPDSLVACIGGG
HHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHCCC
SNAMGLFHPFLDDASVKIIGVEAAGHGIETGQHAASLNGGVPGVLHGNRTFLLQNEDGQI
CCCCHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHCCCCCCEEEECCEEEEEECCCCCE
IDAHSISAGLDYPGIGPEHAWLHDIGRVEYTSITDKEALKAFHTCCRLEGIIPALESSHA
EEECCCCCCCCCCCCCCCHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHCHHHHCCHHH
LAEVFKRAPGLPKDHLMVVNLSGRGDKDMQTVMHHYDEQEEHI
HHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA