Click here to switch to the map view.

The map label for this gene is glpD-1 [H]

Identifier: 146283184

GI number: 146283184

Start: 3065706

End: 3067250

Strand: Direct

Name: glpD-1 [H]

Synonym: PST_2849

Alternate gene names: 146283184

Gene position: 3065706-3067250 (Clockwise)

Preceding gene: 146283182

Following gene: 146283186

Centisome position: 67.12

GC content: 65.24

Gene sequence:

>1545_bases
ATGAATCATCCTCTTCTTGCACCGCTCGCGGAAGTCTACGACCTGGCCGTTGTGGGCGGCGGCATCAACGGCGCGGGAAT
TGCGGCAGACGCCGCAGGTCGTGGCCTGACGGTCTTCCTCTGCGAGCAGGGCGACCTGGCCGAGCACACGTCGTCGGCCA
GCAGCAAGCTGATACATGGCGGGTTGCGCTACCTCGAGCATTACGAACTGCGTCTGGTGCGCGAGGCACTGGCCGAGCGC
GAGGTACTGCTGGCCAAGGCGCCACACATCATTCGGCCACTGCGTTTCGTGCTGCCCTACCGACCGCACCTGCGCCCGTC
CTGGATGATCCGTACCGGCCTGTTCCTCTACGACCACCTCGGCAAGCGCGAGAAGCTAGGCGCTTCGCATAGCGTGCGCT
TCGGCGCCGACAGCCCACTGAAGCACGAGATCAGCCACGGCTTCGAATACGCCGACTGCTGGGTCGACGATGCCCGCCTG
GTGGTGCTCAACGCCATGGCTGCCCGTGAGCAGGGCGCGCATATCCACACCCGCACCCGTTGCGTCAGCGCGCGCAGCAG
CAAGGGGCTGTGGCACCTGCACTTGGAGCGCGACGACGGCAGCCGCTTTTCCATCCGGGCGCGCGCCCTGGTGAACGCCA
CCGGCCCCTGGGTGGCGTCCTTCTTCGATGAACAGCTTCGCCAACGCTCCCCGCACGGCATGCGCCTGATTCAGGGCAGC
CACATCGTGGTGCCGAAGCTCTACGATGGGGACCATGCCTATATCCTGCAGAACGAGGATCGGCGCATCGTCTTCGTCAT
TCCCTATCTCGGGCAGTTCAGCCTGATCGGCACCACCGATCAGGAGTATCACGGTGACCCGACCCGGGTGCAGATCGCCG
ACGGCGAGATCGATTACCTGCTGGACATCGTCAATGCGCACTTCACACACCAGCTGGCCCGTGAAGACATCCGCCACAGC
TACTCCGGCGTCCGCCCGCTGTGCGATGACGAGTCAGACCAACCATCGGCCATCACCCGCGACTACACCCTGACACTGAA
CAACGGCGGCAGCGATGCGCCCCTGCTCTCGGTGTTCGGCGGCAAGCTCACCACCTACCGCAAGCTTGCCGAAGCAGCCC
TGGCCCAGCTGGCACCGCTGTTTCCGGAAATGAAAGGCGCCTGGACCCGCGGAGCGACGCTGCCCGGCGGCGAACACTTC
GATGATCCATCCACTCTGGCCCATGCCCTCTGCGCCAGCTACCCATGGCTTCCCGGCCCGGTCGCCCGCCGCTGGACGAA
CACTTACGGCACGCGCAGCTGGCTGCTGCTCAAGGGCACCGAGCGCATTCAGGATCTCGGCGAATGCTTCGGCGCCGGGC
TGTATGCCCGCGAGGTGGATTACCTGATCGTCGAGGAATGGGCGCTTACGGTTGACGACATTCTCTGGCGCCGAACCAAG
CTCGGGCTGTTCCTGCAAGCCGCCGAAACGGCACGTCTGCAGCAGTACATGGACAGCCGGACCGCCGAACGCCTGACCAC
CTTCGAGCACGCCGCCCAGGGCTGA

Upstream 100 bases:

>100_bases
TTTTTCAACAGGTCGATGGCGGGTGTCATGGCTTTGTAGTGCTAATGATTGATGAATGGCGGTAACGTAACGGATCAACG
TTCGGTAGTCACAAGCGCCC

Downstream 100 bases:

>100_bases
CACGAGCCCCGGACAGCGCCATCGCTCAGGCGACCTTGGCGCTTCGCGCCGCGCGCAGCTGCCGGGCAGCTGCCACCATG
TTCACCAGCGCCGCCTCGGT

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 514; Mature: 514

Protein sequence:

>514_residues
MNHPLLAPLAEVYDLAVVGGGINGAGIAADAAGRGLTVFLCEQGDLAEHTSSASSKLIHGGLRYLEHYELRLVREALAER
EVLLAKAPHIIRPLRFVLPYRPHLRPSWMIRTGLFLYDHLGKREKLGASHSVRFGADSPLKHEISHGFEYADCWVDDARL
VVLNAMAAREQGAHIHTRTRCVSARSSKGLWHLHLERDDGSRFSIRARALVNATGPWVASFFDEQLRQRSPHGMRLIQGS
HIVVPKLYDGDHAYILQNEDRRIVFVIPYLGQFSLIGTTDQEYHGDPTRVQIADGEIDYLLDIVNAHFTHQLAREDIRHS
YSGVRPLCDDESDQPSAITRDYTLTLNNGGSDAPLLSVFGGKLTTYRKLAEAALAQLAPLFPEMKGAWTRGATLPGGEHF
DDPSTLAHALCASYPWLPGPVARRWTNTYGTRSWLLLKGTERIQDLGECFGAGLYAREVDYLIVEEWALTVDDILWRRTK
LGLFLQAAETARLQQYMDSRTAERLTTFEHAAQG

Sequences:

>Translated_514_residues
MNHPLLAPLAEVYDLAVVGGGINGAGIAADAAGRGLTVFLCEQGDLAEHTSSASSKLIHGGLRYLEHYELRLVREALAER
EVLLAKAPHIIRPLRFVLPYRPHLRPSWMIRTGLFLYDHLGKREKLGASHSVRFGADSPLKHEISHGFEYADCWVDDARL
VVLNAMAAREQGAHIHTRTRCVSARSSKGLWHLHLERDDGSRFSIRARALVNATGPWVASFFDEQLRQRSPHGMRLIQGS
HIVVPKLYDGDHAYILQNEDRRIVFVIPYLGQFSLIGTTDQEYHGDPTRVQIADGEIDYLLDIVNAHFTHQLAREDIRHS
YSGVRPLCDDESDQPSAITRDYTLTLNNGGSDAPLLSVFGGKLTTYRKLAEAALAQLAPLFPEMKGAWTRGATLPGGEHF
DDPSTLAHALCASYPWLPGPVARRWTNTYGTRSWLLLKGTERIQDLGECFGAGLYAREVDYLIVEEWALTVDDILWRRTK
LGLFLQAAETARLQQYMDSRTAERLTTFEHAAQG
>Mature_514_residues
MNHPLLAPLAEVYDLAVVGGGINGAGIAADAAGRGLTVFLCEQGDLAEHTSSASSKLIHGGLRYLEHYELRLVREALAER
EVLLAKAPHIIRPLRFVLPYRPHLRPSWMIRTGLFLYDHLGKREKLGASHSVRFGADSPLKHEISHGFEYADCWVDDARL
VVLNAMAAREQGAHIHTRTRCVSARSSKGLWHLHLERDDGSRFSIRARALVNATGPWVASFFDEQLRQRSPHGMRLIQGS
HIVVPKLYDGDHAYILQNEDRRIVFVIPYLGQFSLIGTTDQEYHGDPTRVQIADGEIDYLLDIVNAHFTHQLAREDIRHS
YSGVRPLCDDESDQPSAITRDYTLTLNNGGSDAPLLSVFGGKLTTYRKLAEAALAQLAPLFPEMKGAWTRGATLPGGEHF
DDPSTLAHALCASYPWLPGPVARRWTNTYGTRSWLLLKGTERIQDLGECFGAGLYAREVDYLIVEEWALTVDDILWRRTK
LGLFLQAAETARLQQYMDSRTAERLTTFEHAAQG

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=520, Percent_Identity=30.9615384615385, Blast_Score=167, Evalue=3e-41,
Organism=Homo sapiens, GI285002231, Length=520, Percent_Identity=30.9615384615385, Blast_Score=167, Evalue=3e-41,
Organism=Escherichia coli, GI2367226, Length=472, Percent_Identity=58.0508474576271, Blast_Score=546, Evalue=1e-156,
Organism=Escherichia coli, GI1788574, Length=505, Percent_Identity=25.9405940594059, Blast_Score=79, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI115534726, Length=515, Percent_Identity=29.7087378640777, Blast_Score=148, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI17509253, Length=516, Percent_Identity=29.4573643410853, Blast_Score=143, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6322036, Length=540, Percent_Identity=27.2222222222222, Blast_Score=143, Evalue=5e-35,
Organism=Drosophila melanogaster, GI161077125, Length=522, Percent_Identity=29.8850574712644, Blast_Score=149, Evalue=7e-36,
Organism=Drosophila melanogaster, GI24653942, Length=522, Percent_Identity=29.8850574712644, Blast_Score=149, Evalue=7e-36,
Organism=Drosophila melanogaster, GI24653944, Length=522, Percent_Identity=29.8850574712644, Blast_Score=149, Evalue=7e-36,
Organism=Drosophila melanogaster, GI20130025, Length=522, Percent_Identity=29.8850574712644, Blast_Score=149, Evalue=7e-36,
Organism=Drosophila melanogaster, GI24586295, Length=510, Percent_Identity=27.2549019607843, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI19921278, Length=528, Percent_Identity=24.4318181818182, Blast_Score=98, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 57455; Mature: 57455

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS00977 FAD_G3PDH_1 ; PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHPLLAPLAEVYDLAVVGGGINGAGIAADAAGRGLTVFLCEQGDLAEHTSSASSKLIHG
CCCCCHHHHHHHHEEHEECCCCCCCCEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHH
GLRYLEHYELRLVREALAEREVLLAKAPHIIRPLRFVLPYRPHLRPSWMIRTGLFLYDHL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHC
GKREKLGASHSVRFGADSPLKHEISHGFEYADCWVDDARLVVLNAMAAREQGAHIHTRTR
CCHHHCCCCCCEEECCCCCHHHHHHCCCEEEEEEECCCCEEEEEHHHHHHCCCEEEHHHH
CVSARSSKGLWHLHLERDDGSRFSIRARALVNATGPWVASFFDEQLRQRSPHGMRLIQGS
HHHCCCCCCEEEEEEECCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEECCC
HIVVPKLYDGDHAYILQNEDRRIVFVIPYLGQFSLIGTTDQEYHGDPTRVQIADGEIDYL
EEEEEEEECCCEEEEEECCCCEEEEEEECCCCEEEEECCCCCCCCCCCEEEEECCCHHHH
LDIVNAHFTHQLAREDIRHSYSGVRPLCDDESDQPSAITRDYTLTLNNGGSDAPLLSVFG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCHHHHHC
GKLTTYRKLAEAALAQLAPLFPEMKGAWTRGATLPGGEHFDDPSTLAHALCASYPWLPGP
CCHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCH
VARRWTNTYGTRSWLLLKGTERIQDLGECFGAGLYAREVDYLIVEEWALTVDDILWRRTK
HHHHHCCCCCCCEEEEEECHHHHHHHHHHHCCCHHHHHCCEEEEHHHHHHHHHHHHHHHH
LGLFLQAAETARLQQYMDSRTAERLTTFEHAAQG
HCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNHPLLAPLAEVYDLAVVGGGINGAGIAADAAGRGLTVFLCEQGDLAEHTSSASSKLIHG
CCCCCHHHHHHHHEEHEECCCCCCCCEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHH
GLRYLEHYELRLVREALAEREVLLAKAPHIIRPLRFVLPYRPHLRPSWMIRTGLFLYDHL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHC
GKREKLGASHSVRFGADSPLKHEISHGFEYADCWVDDARLVVLNAMAAREQGAHIHTRTR
CCHHHCCCCCCEEECCCCCHHHHHHCCCEEEEEEECCCCEEEEEHHHHHHCCCEEEHHHH
CVSARSSKGLWHLHLERDDGSRFSIRARALVNATGPWVASFFDEQLRQRSPHGMRLIQGS
HHHCCCCCCEEEEEEECCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEECCC
HIVVPKLYDGDHAYILQNEDRRIVFVIPYLGQFSLIGTTDQEYHGDPTRVQIADGEIDYL
EEEEEEEECCCEEEEEECCCCEEEEEEECCCCEEEEECCCCCCCCCCCEEEEECCCHHHH
LDIVNAHFTHQLAREDIRHSYSGVRPLCDDESDQPSAITRDYTLTLNNGGSDAPLLSVFG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCHHHHHC
GKLTTYRKLAEAALAQLAPLFPEMKGAWTRGATLPGGEHFDDPSTLAHALCASYPWLPGP
CCHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCH
VARRWTNTYGTRSWLLLKGTERIQDLGECFGAGLYAREVDYLIVEEWALTVDDILWRRTK
HHHHHCCCCCCCEEEEEECHHHHHHHHHHHCCCHHHHHCCEEEEHHHHHHHHHHHHHHHH
LGLFLQAAETARLQQYMDSRTAERLTTFEHAAQG
HCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8157588; 10984043 [H]