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The map label for this gene is qseC [H]

Identifier: 146283049

GI number: 146283049

Start: 2933589

End: 2934911

Strand: Direct

Name: qseC [H]

Synonym: PST_2710

Alternate gene names: 146283049

Gene position: 2933589-2934911 (Clockwise)

Preceding gene: 146283048

Following gene: 146283052

Centisome position: 64.23

GC content: 70.75

Gene sequence:

>1323_bases
ATGAGCCTGCGCCTGCGCCTGACCCTGATGCTCGGCTCGGCCTTCGTGCTGCTCTGGGCATTGGCTGCGACCTGGATGCT
GGTCGATCTGCGCAGCCAGATGATGCTCTCGCTCGACCAGCGCCTGGCGGCCTCGGCGCGCATGGTCGCCGGTCTGCTGG
TGCAGTTGCCGCAGCCGGTGCCCGGCGACGGCCCGCCGCAGCGTCTGAGCGCCGAGCAACTGGGCATACCCAACGGCCTG
GCCTGCCAGGTCAGCTCGCTGCGTGGCGAGGTGCTGGCGCGTAGCCACAGTGCGCCCGACCAGCAGCTGGACGCCGAGCA
GAACGGCTTTCGCGACCAGTTGATCGACGGCGTGCCCTGGCGCAGCTTCACCCTGGTGCAAGGCGAGCTGCGCATCACCA
CGGCCGACCGTCTGGACGAGCGTGCCGCGCTGAAGCGCTCGGTGTTGCTGGCGGCGGCGCTGCCAGTGGCGGTCGCTCTG
CTCGGCAGCCTGGCTCTGCTCTGGCTCGGCCTGGGCCGTGGGCTGGCGCCCCTGCGCAGGATTCGCGAGGCACTGACCCG
ACGCAGCGCCGACTCCCTCGAACCCTTGCCGGTCGAAGGTCTGCCGCCGGAGCTGCTGCCGCTGGTGCAGACGCAGAACC
AGCTATTCCAGCGCATCGCCCAGGCCATCGAAGGCGAACGTCGGCTGACCGGCGACGCCGCCCACGAGCTGCGCAGCCCG
CTGACGGTGATCAAGACCCACCTGCAGGTGGCACGCATGACCGAAGGCGCCGCTGCCGAACTGGCACTGGCCAACGCCGA
GGCCGGCGCCGACCGCCTGCAGCGTACGCTCGAGCAGTTGCTGTTGCTGGCCCGGGTAGAAGGCAGTCTGGATTTCGACG
ATGGCCTGCAGTGCACGGCCGCCGAGGTCGCGCGACTGGCGATTCAGGACGCCAGTGGCGGTGACGGCGCGCCGATCCTG
TTGCAGGTCCCGGCGGACCTGCCCGACACGCCGCTGGCCATGCCGCCGGTACTGGCCATCGCCGCGCTGCGCAACCTGCT
GGAGAATGCCCAGCGCCACACCGCGCCGGGCAGCGCCGTCACGCTGATCCTGCAGCCTGAAGCCGGGCGAGTACGCTTCG
AAGTACGCGACCAGGGGCCGGGCATCGCCGCCGAGCATCTCGAGCACCTGACCCGGCGCTTCTGGCGACACGCCGCCAGC
AGTGGCAGCGGCCTGGGCCTGGCCATCGTCCAAGCGATCGCGCAACGCTGCGATTGCACCCTCGCCTTCGACAGCCAGGG
CGACGGCCTGCGCGTATCACTGGCGGTGCCGTTGCAGCGCTGA

Upstream 100 bases:

>100_bases
TGCATATCCACCATCTGCGCCGCAAGCTCGGCAGCGGCATCGTCGAAACCGTCCGAGGCCTCGGCTACCGCCTCGGCCTC
GCAGGCGACGAGGACGCGCC

Downstream 100 bases:

>100_bases
TCAGTTCGGGAATTCCAGCACGAAAGACGTCCGGCCCTGCGCGGAAGTGCAATGGATACGACCCTGATGGGCCTGAACGA
TCGAACGGGTAATCGCCAGC

Product: two-component sensor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MSLRLRLTLMLGSAFVLLWALAATWMLVDLRSQMMLSLDQRLAASARMVAGLLVQLPQPVPGDGPPQRLSAEQLGIPNGL
ACQVSSLRGEVLARSHSAPDQQLDAEQNGFRDQLIDGVPWRSFTLVQGELRITTADRLDERAALKRSVLLAAALPVAVAL
LGSLALLWLGLGRGLAPLRRIREALTRRSADSLEPLPVEGLPPELLPLVQTQNQLFQRIAQAIEGERRLTGDAAHELRSP
LTVIKTHLQVARMTEGAAAELALANAEAGADRLQRTLEQLLLLARVEGSLDFDDGLQCTAAEVARLAIQDASGGDGAPIL
LQVPADLPDTPLAMPPVLAIAALRNLLENAQRHTAPGSAVTLILQPEAGRVRFEVRDQGPGIAAEHLEHLTRRFWRHAAS
SGSGLGLAIVQAIAQRCDCTLAFDSQGDGLRVSLAVPLQR

Sequences:

>Translated_440_residues
MSLRLRLTLMLGSAFVLLWALAATWMLVDLRSQMMLSLDQRLAASARMVAGLLVQLPQPVPGDGPPQRLSAEQLGIPNGL
ACQVSSLRGEVLARSHSAPDQQLDAEQNGFRDQLIDGVPWRSFTLVQGELRITTADRLDERAALKRSVLLAAALPVAVAL
LGSLALLWLGLGRGLAPLRRIREALTRRSADSLEPLPVEGLPPELLPLVQTQNQLFQRIAQAIEGERRLTGDAAHELRSP
LTVIKTHLQVARMTEGAAAELALANAEAGADRLQRTLEQLLLLARVEGSLDFDDGLQCTAAEVARLAIQDASGGDGAPIL
LQVPADLPDTPLAMPPVLAIAALRNLLENAQRHTAPGSAVTLILQPEAGRVRFEVRDQGPGIAAEHLEHLTRRFWRHAAS
SGSGLGLAIVQAIAQRCDCTLAFDSQGDGLRVSLAVPLQR
>Mature_439_residues
SLRLRLTLMLGSAFVLLWALAATWMLVDLRSQMMLSLDQRLAASARMVAGLLVQLPQPVPGDGPPQRLSAEQLGIPNGLA
CQVSSLRGEVLARSHSAPDQQLDAEQNGFRDQLIDGVPWRSFTLVQGELRITTADRLDERAALKRSVLLAAALPVAVALL
GSLALLWLGLGRGLAPLRRIREALTRRSADSLEPLPVEGLPPELLPLVQTQNQLFQRIAQAIEGERRLTGDAAHELRSPL
TVIKTHLQVARMTEGAAAELALANAEAGADRLQRTLEQLLLLARVEGSLDFDDGLQCTAAEVARLAIQDASGGDGAPILL
QVPADLPDTPLAMPPVLAIAALRNLLENAQRHTAPGSAVTLILQPEAGRVRFEVRDQGPGIAAEHLEHLTRRFWRHAASS
GSGLGLAIVQAIAQRCDCTLAFDSQGDGLRVSLAVPLQR

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. May activate qseB by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=454, Percent_Identity=32.15859030837, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1790551, Length=285, Percent_Identity=30.1754385964912, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786600, Length=234, Percent_Identity=30.7692307692308, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1786783, Length=335, Percent_Identity=25.3731343283582, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1790346, Length=275, Percent_Identity=27.6363636363636, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1788279, Length=291, Percent_Identity=28.8659793814433, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1788393, Length=283, Percent_Identity=28.2685512367491, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790861, Length=303, Percent_Identity=27.0627062706271, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 47208; Mature: 47077

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLRLRLTLMLGSAFVLLWALAATWMLVDLRSQMMLSLDQRLAASARMVAGLLVQLPQPV
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PGDGPPQRLSAEQLGIPNGLACQVSSLRGEVLARSHSAPDQQLDAEQNGFRDQLIDGVPW
CCCCCHHHCCHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHCCCHHCCCHHHHHCCCCC
RSFTLVQGELRITTADRLDERAALKRSVLLAAALPVAVALLGSLALLWLGLGRGLAPLRR
CCEEEEECEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
IREALTRRSADSLEPLPVEGLPPELLPLVQTQNQLFQRIAQAIEGERRLTGDAAHELRSP
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHCH
LTVIKTHLQVARMTEGAAAELALANAEAGADRLQRTLEQLLLLARVEGSLDFDDGLQCTA
HHHHHHHHHHHHHCCCCHHHHEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
AEVARLAIQDASGGDGAPILLQVPADLPDTPLAMPPVLAIAALRNLLENAQRHTAPGSAV
HHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEE
TLILQPEAGRVRFEVRDQGPGIAAEHLEHLTRRFWRHAASSGSGLGLAIVQAIAQRCDCT
EEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCEE
LAFDSQGDGLRVSLAVPLQR
EEECCCCCCEEEEEECCCCC
>Mature Secondary Structure 
SLRLRLTLMLGSAFVLLWALAATWMLVDLRSQMMLSLDQRLAASARMVAGLLVQLPQPV
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PGDGPPQRLSAEQLGIPNGLACQVSSLRGEVLARSHSAPDQQLDAEQNGFRDQLIDGVPW
CCCCCHHHCCHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHCCCHHCCCHHHHHCCCCC
RSFTLVQGELRITTADRLDERAALKRSVLLAAALPVAVALLGSLALLWLGLGRGLAPLRR
CCEEEEECEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
IREALTRRSADSLEPLPVEGLPPELLPLVQTQNQLFQRIAQAIEGERRLTGDAAHELRSP
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHCH
LTVIKTHLQVARMTEGAAAELALANAEAGADRLQRTLEQLLLLARVEGSLDFDDGLQCTA
HHHHHHHHHHHHHCCCCHHHHEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
AEVARLAIQDASGGDGAPILLQVPADLPDTPLAMPPVLAIAALRNLLENAQRHTAPGSAV
HHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEE
TLILQPEAGRVRFEVRDQGPGIAAEHLEHLTRRFWRHAASSGSGLGLAIVQAIAQRCDCT
EEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCEE
LAFDSQGDGLRVSLAVPLQR
EEECCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]