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The map label for this gene is qseB [H]

Identifier: 146283048

GI number: 146283048

Start: 2932915

End: 2933592

Strand: Direct

Name: qseB [H]

Synonym: PST_2709

Alternate gene names: 146283048

Gene position: 2932915-2933592 (Clockwise)

Preceding gene: 146283044

Following gene: 146283049

Centisome position: 64.21

GC content: 69.76

Gene sequence:

>678_bases
ATGCACGTGCTGCTTGCCGAAGACGACGCGCTGATCGCCAGCGGTATCGTCGCCGGGCTCAACGCCCAGGGCCTGATCGT
CGACCATGCCGCGACCGCGGCGGCTGCCGAAGCCCTGCTGCGTGCGGCGCACTTCGATGTGCTGATCCTCGACCTCGGCC
TGCCCGACGAAGACGGCCTCGCCCTGTTGCGACGCCTGCGCCAGCAGGGCCTGGAGCTGCCGGTGCTGGTGCTCACCGCG
CGCGATGCGGTCAGCGACCGGGTCACCGGCCTGCAGGCGGGGGCCGACGATTACCTGCTCAAGCCCTTCGACCTGCGCGA
GCTGGCCGCGCGCCTGCACACGCTGATGCGGCGCATGTCCGGCCGCAGCGTCAACCTCATCGAGCATGGCCGGCTGAGCT
ACGACCCGAGCCGCTGCGAAGCACGCCTGGACGGCCGCCTGGTCGACCTGTCGCGCCGCGAACAGGCACTGCTGCAGGCA
CTGCTCAACAACCAGGGCCGGGTGCTCAGCAGCGAGCAGCTCAAGGACGCGGTCTACGGTTTTGCCGACGACGTCGAGAG
CAACGCGCTGAACGTGCATATCCACCATCTGCGCCGCAAGCTCGGCAGCGGCATCGTCGAAACCGTCCGAGGCCTCGGCT
ACCGCCTCGGCCTCGCAGGCGACGAGGACGCGCCATGA

Upstream 100 bases:

>100_bases
CGGGACGGGATTAACGCGCCATTAACGCCATGGCACGGGCTGCATAACGTTGCCTTAATCGCTAAGGTCCACCCTTGAGC
TTTTTCTGCGGACCCTCCCC

Downstream 100 bases:

>100_bases
GCCTGCGCCTGCGCCTGACCCTGATGCTCGGCTCGGCCTTCGTGCTGCTCTGGGCATTGGCTGCGACCTGGATGCTGGTC
GATCTGCGCAGCCAGATGAT

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MHVLLAEDDALIASGIVAGLNAQGLIVDHAATAAAAEALLRAAHFDVLILDLGLPDEDGLALLRRLRQQGLELPVLVLTA
RDAVSDRVTGLQAGADDYLLKPFDLRELAARLHTLMRRMSGRSVNLIEHGRLSYDPSRCEARLDGRLVDLSRREQALLQA
LLNNQGRVLSSEQLKDAVYGFADDVESNALNVHIHHLRRKLGSGIVETVRGLGYRLGLAGDEDAP

Sequences:

>Translated_225_residues
MHVLLAEDDALIASGIVAGLNAQGLIVDHAATAAAAEALLRAAHFDVLILDLGLPDEDGLALLRRLRQQGLELPVLVLTA
RDAVSDRVTGLQAGADDYLLKPFDLRELAARLHTLMRRMSGRSVNLIEHGRLSYDPSRCEARLDGRLVDLSRREQALLQA
LLNNQGRVLSSEQLKDAVYGFADDVESNALNVHIHHLRRKLGSGIVETVRGLGYRLGLAGDEDAP
>Mature_225_residues
MHVLLAEDDALIASGIVAGLNAQGLIVDHAATAAAAEALLRAAHFDVLILDLGLPDEDGLALLRRLRQQGLELPVLVLTA
RDAVSDRVTGLQAGADDYLLKPFDLRELAARLHTLMRRMSGRSVNLIEHGRLSYDPSRCEARLDGRLVDLSRREQALLQA
LLNNQGRVLSSEQLKDAVYGFADDVESNALNVHIHHLRRKLGSGIVETVRGLGYRLGLAGDEDAP

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=217, Percent_Identity=48.8479262672811, Blast_Score=201, Evalue=2e-53,
Organism=Escherichia coli, GI1790552, Length=223, Percent_Identity=41.7040358744395, Blast_Score=176, Evalue=8e-46,
Organism=Escherichia coli, GI1787375, Length=222, Percent_Identity=39.1891891891892, Blast_Score=149, Evalue=1e-37,
Organism=Escherichia coli, GI1786599, Length=222, Percent_Identity=35.5855855855856, Blast_Score=126, Evalue=9e-31,
Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=39.9103139013453, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI1786784, Length=221, Percent_Identity=33.9366515837104, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1786911, Length=228, Percent_Identity=39.0350877192982, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=32.2727272727273, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1789809, Length=225, Percent_Identity=32, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1788394, Length=228, Percent_Identity=31.5789473684211, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1787229, Length=224, Percent_Identity=30.3571428571429, Blast_Score=103, Evalue=8e-24,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=35.2422907488987, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=29.6943231441048, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI145693140, Length=229, Percent_Identity=26.6375545851528, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1790299, Length=108, Percent_Identity=36.1111111111111, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1788550, Length=106, Percent_Identity=32.0754716981132, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788713, Length=115, Percent_Identity=33.9130434782609, Blast_Score=63, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24426; Mature: 24426

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHVLLAEDDALIASGIVAGLNAQGLIVDHAATAAAAEALLRAAHFDVLILDLGLPDEDGL
CEEEEECCCHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHCCEEEEECCCCCCCHH
ALLRRLRQQGLELPVLVLTARDAVSDRVTGLQAGADDYLLKPFDLRELAARLHTLMRRMS
HHHHHHHHCCCCCCEEEEECCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
GRSVNLIEHGRLSYDPSRCEARLDGRLVDLSRREQALLQALLNNQGRVLSSEQLKDAVYG
CCEEEEEECCCCCCCHHHHHHHHCCEEECHHHHHHHHHHHHHCCCCCEECHHHHHHHHHH
FADDVESNALNVHIHHLRRKLGSGIVETVRGLGYRLGLAGDEDAP
HHHCCCCCEEEEHHHHHHHHHCCCHHHHHHHCCEEECCCCCCCCC
>Mature Secondary Structure
MHVLLAEDDALIASGIVAGLNAQGLIVDHAATAAAAEALLRAAHFDVLILDLGLPDEDGL
CEEEEECCCHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHCCEEEEECCCCCCCHH
ALLRRLRQQGLELPVLVLTARDAVSDRVTGLQAGADDYLLKPFDLRELAARLHTLMRRMS
HHHHHHHHCCCCCCEEEEECCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
GRSVNLIEHGRLSYDPSRCEARLDGRLVDLSRREQALLQALLNNQGRVLSSEQLKDAVYG
CCEEEEEECCCCCCCHHHHHHHHCCEEECHHHHHHHHHHHHHCCCCCEECHHHHHHHHHH
FADDVESNALNVHIHHLRRKLGSGIVETVRGLGYRLGLAGDEDAP
HHHCCCCCEEEEHHHHHHHHHCCCHHHHHHHCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]