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The map label for this gene is plsB [H]

Identifier: 146283042

GI number: 146283042

Start: 2925546

End: 2928104

Strand: Direct

Name: plsB [H]

Synonym: PST_2703

Alternate gene names: 146283042

Gene position: 2925546-2928104 (Clockwise)

Preceding gene: 146283041

Following gene: 146283044

Centisome position: 64.05

GC content: 65.42

Gene sequence:

>2559_bases
TTGGGGCACACTTGCCGCCTTCGAGGGCTCCGCCCCTTCCACAGTCGAATCCGCCGTATGACCCGCTCCCCCGTTCGCCG
TCTGATCTTCTCCCTGGTGCGCCGTGTGCTGTACACCTGGGTGCGCTCGGAGACCATCAACCAGTCCGCCTTCACCCTCA
AGCTGGATCGCAGCAAGCCGGTGTTCTATGTGCTGCAGCAACCCTCGCTGAGCGATCTCGCCGTGCTCGATGCCGAGTGC
AGCAAGGCCGGGCTGCCACGCCCGGTGGCCGATGTGGCGGTGGGCGAACTGGTGGAGCCGGCCGCCTTCTTCTTCCTCAA
TCCGGCACCCAGCTGGTTCGGCCGGCGTACCCGCCTGGTCGCGCCACCGGCGCTGGTGCGGCTGGTCGGCGCGCTGGAGC
ACAACGCGGTAGAGAACGCGCAGATCGTTCCGGTCAGCGTGTTCTGGGGGCAGTCGCCGAATCGCGAGACCAGCGCCTGG
AAGCTGCTGTTCGCCGACAGCTGGGCGGTCACCGGGCGCCTGCGCAAGCTGCTCAGCATCCTGGTGCTGGGGCGCAAGAC
GCGCGTGCAGTTCTCCGCGCCGATCCAGCTCAACGAACTCATCGCCCAGAACAAGGGGCACGAGCGCACACTGCGCATGG
TCCATCGCATGCTGCGGGTGCACTTCCGCAACCAGAAGACCGCGGTGATCGGCCCGGACCTGTCGCACCGGCGCAATCTG
GTGAAGGGCCTGGTGCACGCACCACAGGTCCGCCAGGCGATTCGCGAGGAAGCCGAACGCGAGAAGATCACCATCGAGAA
GGCCGAGGCCAAGGCGCTGCGCTATGGCAACGAGATCGCCTCGGACTACGCGTATACGGCGGTGCGCTTTCTCGAGGTTG
TGCTGTCCTGGTTCTGGAACAAGATCTACGACGGCATCCGCGTCAACCATATCGAGCCCTTGCAGGACGCCGTCCGCGGC
TACGAAGTGATCTACGTGCCCTGCCACCGTAGCCACATCGATTACCTGCTGCTCTCCTACCTGCTGTTTCGCAACGGCCT
TACCCCGCCGCACATCGCCGCCGGCATCAACCTCAACATGCCGGTGATCGGCAGCCTGCTGCGCCGCGGCGGCGCCTTCT
TCATGCGCCGCTCGTTCAAGGGCAACCCGCTGTACACCTCGGTGTTCAACGAATACCTGCACAACCTGTTCACCCGCGGC
TTCCCCGTCGAGTACTTCGTGGAAGGCGGGCGTTCGCGTACCGGCCGCATGCTGCAACCCAAGACCGGCATGCTGGCGCT
GACCCTGCGCAGCTACCTGCGCTCGTCGCGCCTGCCGATCCTCTTCGTGCCGGTCTACATCGGCTACGAGCGGGTGCTGG
AGGGCCGCACCTACCTCGGCGAATTGCGCGGCGCGGCGAAGAAGAAGGAGTCGATCTTCGACATCTTCAAGGTCATCGGC
GCCCTCAAGCAGCGCTTTGGGCAGGTCTGGGTAAACTTCGGCGAGCCGCTCAAGCTCAACGAATTCCTCGAGCAGGAGCA
ACCCGGCTGGCGCCAGCAGGCCTATGCGCCGGACTATCGCCCGCAGTGGCTGAACGACGCCACCAACCACCTGGCCGAGC
GCATCGCCCAGCGCCTCAACGAGGCGGCGGCCGTCAACCCGGTCAACCTGGTGGCGCTGGCGATGCTCTCCACCAGCCGT
CAGGCGCTGGACCAGCAATCCCTGGCACGCATCCTCGATCTCTACCAGGCGCTGTTGCGCGCAGTGCCCTATTCGCCGCA
CACCACGCTGCCGGAGGGAGACGGCAACGCACTGATCGCCTACGTGAAGAGCCTCGACCTGCTCGCCGAGCAGAAGGACG
CACTGGGCAACATCCTCTATCTGGACGAGCAGAATGCCGTCCTGATGACCTACTACCGCAACAACGTGATGCATATCTTC
GCCCTGCCCGCACTGCTGGCGAGCTTCTTCCAGAGCAGCTCACGCATCAGCCGCGAGCAGATCCAGCGTTTCACCGAGGC
GCTGTACCCCTATCTGCGTGCCGAGCTGTTCATGCGCTGGGAGGTCGAGGAGCTGGAAGCGGTGGTCGATCAGTGGCTGG
CGGCCTTCGTCGAGCACGGCCTGCTCAAGGTGGACGGCAACCACTACGTGCGCCCGGCGCCAAGTTCGCGGCAGTTCGTT
CTGCTCACCCTGCTGGCGCGGGTGGTGATGCAGACCCTGCAGCGCTTCTACATGGCCACCTCGCTGCTGCTCAACAGCGG
CCAGCACAGCCTGAGCGCCGAGGAGCTGGAGAATCTCTGCACGGTCATGGCCCAACGCCTGTCGATACTCCACGGGCTCA
ACGCGCCCGAGTTCTTCGACAAGACGCTGTTCCGCCACTTCATTCAGAGCATGCAGGAACAGGGCGTGGTCAGCACGGAT
GCCAACGGTCGCCTGGGCTACCACGAAAAGCTCGCGGAGCTGGCCGAGGGTGCCGCCAAGCGCGTGCTGCCGGCGGAGAT
TCGGCTGTCGATCCGGCAGGTCGCACTGGAGCGCCATCATGACGACAGCGAGGCGCCGCCGCCGCCGACCGACGCCTGA

Upstream 100 bases:

>100_bases
CACGGGCGTTGACCGATTTCGCTCGAGTTCTGCCGGCAGCCATACACCGGTGTGGATCAGGCACTGACAGAGCAGCGCAG
GTTTTGCCCGGCCACCTCGC

Downstream 100 bases:

>100_bases
CGCTGCCAGGTCATCAGGCGTTCCGGGTGGCCGGTGTGTGCGTCCAGTTGCTCGCCTGCGACTCGGAAGCCGTGACGACG
ATAGAAGGCGATACTGGCGC

Product: glycerol-3-phosphate acyltransferase

Products: NA

Alternate protein names: GPAT [H]

Number of amino acids: Translated: 852; Mature: 851

Protein sequence:

>852_residues
MGHTCRLRGLRPFHSRIRRMTRSPVRRLIFSLVRRVLYTWVRSETINQSAFTLKLDRSKPVFYVLQQPSLSDLAVLDAEC
SKAGLPRPVADVAVGELVEPAAFFFLNPAPSWFGRRTRLVAPPALVRLVGALEHNAVENAQIVPVSVFWGQSPNRETSAW
KLLFADSWAVTGRLRKLLSILVLGRKTRVQFSAPIQLNELIAQNKGHERTLRMVHRMLRVHFRNQKTAVIGPDLSHRRNL
VKGLVHAPQVRQAIREEAEREKITIEKAEAKALRYGNEIASDYAYTAVRFLEVVLSWFWNKIYDGIRVNHIEPLQDAVRG
YEVIYVPCHRSHIDYLLLSYLLFRNGLTPPHIAAGINLNMPVIGSLLRRGGAFFMRRSFKGNPLYTSVFNEYLHNLFTRG
FPVEYFVEGGRSRTGRMLQPKTGMLALTLRSYLRSSRLPILFVPVYIGYERVLEGRTYLGELRGAAKKKESIFDIFKVIG
ALKQRFGQVWVNFGEPLKLNEFLEQEQPGWRQQAYAPDYRPQWLNDATNHLAERIAQRLNEAAAVNPVNLVALAMLSTSR
QALDQQSLARILDLYQALLRAVPYSPHTTLPEGDGNALIAYVKSLDLLAEQKDALGNILYLDEQNAVLMTYYRNNVMHIF
ALPALLASFFQSSSRISREQIQRFTEALYPYLRAELFMRWEVEELEAVVDQWLAAFVEHGLLKVDGNHYVRPAPSSRQFV
LLTLLARVVMQTLQRFYMATSLLLNSGQHSLSAEELENLCTVMAQRLSILHGLNAPEFFDKTLFRHFIQSMQEQGVVSTD
ANGRLGYHEKLAELAEGAAKRVLPAEIRLSIRQVALERHHDDSEAPPPPTDA

Sequences:

>Translated_852_residues
MGHTCRLRGLRPFHSRIRRMTRSPVRRLIFSLVRRVLYTWVRSETINQSAFTLKLDRSKPVFYVLQQPSLSDLAVLDAEC
SKAGLPRPVADVAVGELVEPAAFFFLNPAPSWFGRRTRLVAPPALVRLVGALEHNAVENAQIVPVSVFWGQSPNRETSAW
KLLFADSWAVTGRLRKLLSILVLGRKTRVQFSAPIQLNELIAQNKGHERTLRMVHRMLRVHFRNQKTAVIGPDLSHRRNL
VKGLVHAPQVRQAIREEAEREKITIEKAEAKALRYGNEIASDYAYTAVRFLEVVLSWFWNKIYDGIRVNHIEPLQDAVRG
YEVIYVPCHRSHIDYLLLSYLLFRNGLTPPHIAAGINLNMPVIGSLLRRGGAFFMRRSFKGNPLYTSVFNEYLHNLFTRG
FPVEYFVEGGRSRTGRMLQPKTGMLALTLRSYLRSSRLPILFVPVYIGYERVLEGRTYLGELRGAAKKKESIFDIFKVIG
ALKQRFGQVWVNFGEPLKLNEFLEQEQPGWRQQAYAPDYRPQWLNDATNHLAERIAQRLNEAAAVNPVNLVALAMLSTSR
QALDQQSLARILDLYQALLRAVPYSPHTTLPEGDGNALIAYVKSLDLLAEQKDALGNILYLDEQNAVLMTYYRNNVMHIF
ALPALLASFFQSSSRISREQIQRFTEALYPYLRAELFMRWEVEELEAVVDQWLAAFVEHGLLKVDGNHYVRPAPSSRQFV
LLTLLARVVMQTLQRFYMATSLLLNSGQHSLSAEELENLCTVMAQRLSILHGLNAPEFFDKTLFRHFIQSMQEQGVVSTD
ANGRLGYHEKLAELAEGAAKRVLPAEIRLSIRQVALERHHDDSEAPPPPTDA
>Mature_851_residues
GHTCRLRGLRPFHSRIRRMTRSPVRRLIFSLVRRVLYTWVRSETINQSAFTLKLDRSKPVFYVLQQPSLSDLAVLDAECS
KAGLPRPVADVAVGELVEPAAFFFLNPAPSWFGRRTRLVAPPALVRLVGALEHNAVENAQIVPVSVFWGQSPNRETSAWK
LLFADSWAVTGRLRKLLSILVLGRKTRVQFSAPIQLNELIAQNKGHERTLRMVHRMLRVHFRNQKTAVIGPDLSHRRNLV
KGLVHAPQVRQAIREEAEREKITIEKAEAKALRYGNEIASDYAYTAVRFLEVVLSWFWNKIYDGIRVNHIEPLQDAVRGY
EVIYVPCHRSHIDYLLLSYLLFRNGLTPPHIAAGINLNMPVIGSLLRRGGAFFMRRSFKGNPLYTSVFNEYLHNLFTRGF
PVEYFVEGGRSRTGRMLQPKTGMLALTLRSYLRSSRLPILFVPVYIGYERVLEGRTYLGELRGAAKKKESIFDIFKVIGA
LKQRFGQVWVNFGEPLKLNEFLEQEQPGWRQQAYAPDYRPQWLNDATNHLAERIAQRLNEAAAVNPVNLVALAMLSTSRQ
ALDQQSLARILDLYQALLRAVPYSPHTTLPEGDGNALIAYVKSLDLLAEQKDALGNILYLDEQNAVLMTYYRNNVMHIFA
LPALLASFFQSSSRISREQIQRFTEALYPYLRAELFMRWEVEELEAVVDQWLAAFVEHGLLKVDGNHYVRPAPSSRQFVL
LTLLARVVMQTLQRFYMATSLLLNSGQHSLSAEELENLCTVMAQRLSILHGLNAPEFFDKTLFRHFIQSMQEQGVVSTDA
NGRLGYHEKLAELAEGAAKRVLPAEIRLSIRQVALERHHDDSEAPPPPTDA

Specific function: De novo phospholipid biosynthesis; first step. [C]

COG id: COG2937

COG function: function code I; Glycerol-3-phosphate O-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPAT/DAPAT family [H]

Homologues:

Organism=Homo sapiens, GI7657134, Length=411, Percent_Identity=31.3868613138686, Blast_Score=190, Evalue=5e-48,
Organism=Homo sapiens, GI190358539, Length=560, Percent_Identity=25.1785714285714, Blast_Score=159, Evalue=1e-38,
Organism=Escherichia coli, GI87082362, Length=811, Percent_Identity=38.7176325524044, Blast_Score=541, Evalue=1e-155,
Organism=Caenorhabditis elegans, GI25147672, Length=343, Percent_Identity=33.2361516034985, Blast_Score=173, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI71988723, Length=657, Percent_Identity=23.5920852359209, Blast_Score=146, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI71988728, Length=563, Percent_Identity=24.3339253996448, Blast_Score=136, Evalue=5e-32,
Organism=Drosophila melanogaster, GI17864692, Length=324, Percent_Identity=31.1728395061728, Blast_Score=172, Evalue=1e-42,
Organism=Drosophila melanogaster, GI21357731, Length=448, Percent_Identity=29.4642857142857, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24650754, Length=445, Percent_Identity=29.2134831460674, Blast_Score=157, Evalue=3e-38,
Organism=Drosophila melanogaster, GI24650752, Length=441, Percent_Identity=29.2517006802721, Blast_Score=157, Evalue=4e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR022284 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.15 [H]

Molecular weight: Translated: 97130; Mature: 96998

Theoretical pI: Translated: 10.11; Mature: 10.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGHTCRLRGLRPFHSRIRRMTRSPVRRLIFSLVRRVLYTWVRSETINQSAFTLKLDRSKP
CCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCC
VFYVLQQPSLSDLAVLDAECSKAGLPRPVADVAVGELVEPAAFFFLNPAPSWFGRRTRLV
EEEEECCCCCCHHHHCCCHHHHCCCCCCHHHHHHHHHHCCHHHEEECCCCHHHCCCCEEC
APPALVRLVGALEHNAVENAQIVPVSVFWGQSPNRETSAWKLLFADSWAVTGRLRKLLSI
CCHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCCEEEEEECCHHHHHHHHHHHHH
LVLGRKTRVQFSAPIQLNELIAQNKGHERTLRMVHRMLRVHFRNQKTAVIGPDLSHRRNL
HHHCCCCCEEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHH
VKGLVHAPQVRQAIREEAEREKITIEKAEAKALRYGNEIASDYAYTAVRFLEVVLSWFWN
HHHHHCCHHHHHHHHHHHHHHHEEHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHH
KIYDGIRVNHIEPLQDAVRGYEVIYVPCHRSHIDYLLLSYLLFRNGLTPPHIAAGINLNM
HHHCCCEECCCCHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCHHCCCCCCCH
PVIGSLLRRGGAFFMRRSFKGNPLYTSVFNEYLHNLFTRGFPVEYFVEGGRSRTGRMLQP
HHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCC
KTGMLALTLRSYLRSSRLPILFVPVYIGYERVLEGRTYLGELRGAAKKKESIFDIFKVIG
CCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALKQRFGQVWVNFGEPLKLNEFLEQEQPGWRQQAYAPDYRPQWLNDATNHLAERIAQRLN
HHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
EAAAVNPVNLVALAMLSTSRQALDQQSLARILDLYQALLRAVPYSPHTTLPEGDGNALIA
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHH
YVKSLDLLAEQKDALGNILYLDEQNAVLMTYYRNNVMHIFALPALLASFFQSSSRISREQ
HHHHHHHHHHHHHHCCCEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHH
IQRFTEALYPYLRAELFMRWEVEELEAVVDQWLAAFVEHGLLKVDGNHYVRPAPSSRQFV
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEECCCEEECCCCCCCCHH
LLTLLARVVMQTLQRFYMATSLLLNSGQHSLSAEELENLCTVMAQRLSILHGLNAPEFFD
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHH
KTLFRHFIQSMQEQGVVSTDANGRLGYHEKLAELAEGAAKRVLPAEIRLSIRQVALERHH
HHHHHHHHHHHHHCCCEECCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
DDSEAPPPPTDA
CCCCCCCCCCCC
>Mature Secondary Structure 
GHTCRLRGLRPFHSRIRRMTRSPVRRLIFSLVRRVLYTWVRSETINQSAFTLKLDRSKP
CCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCC
VFYVLQQPSLSDLAVLDAECSKAGLPRPVADVAVGELVEPAAFFFLNPAPSWFGRRTRLV
EEEEECCCCCCHHHHCCCHHHHCCCCCCHHHHHHHHHHCCHHHEEECCCCHHHCCCCEEC
APPALVRLVGALEHNAVENAQIVPVSVFWGQSPNRETSAWKLLFADSWAVTGRLRKLLSI
CCHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCCEEEEEECCHHHHHHHHHHHHH
LVLGRKTRVQFSAPIQLNELIAQNKGHERTLRMVHRMLRVHFRNQKTAVIGPDLSHRRNL
HHHCCCCCEEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHH
VKGLVHAPQVRQAIREEAEREKITIEKAEAKALRYGNEIASDYAYTAVRFLEVVLSWFWN
HHHHHCCHHHHHHHHHHHHHHHEEHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHH
KIYDGIRVNHIEPLQDAVRGYEVIYVPCHRSHIDYLLLSYLLFRNGLTPPHIAAGINLNM
HHHCCCEECCCCHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCHHCCCCCCCH
PVIGSLLRRGGAFFMRRSFKGNPLYTSVFNEYLHNLFTRGFPVEYFVEGGRSRTGRMLQP
HHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCC
KTGMLALTLRSYLRSSRLPILFVPVYIGYERVLEGRTYLGELRGAAKKKESIFDIFKVIG
CCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALKQRFGQVWVNFGEPLKLNEFLEQEQPGWRQQAYAPDYRPQWLNDATNHLAERIAQRLN
HHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
EAAAVNPVNLVALAMLSTSRQALDQQSLARILDLYQALLRAVPYSPHTTLPEGDGNALIA
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHH
YVKSLDLLAEQKDALGNILYLDEQNAVLMTYYRNNVMHIFALPALLASFFQSSSRISREQ
HHHHHHHHHHHHHHCCCEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHH
IQRFTEALYPYLRAELFMRWEVEELEAVVDQWLAAFVEHGLLKVDGNHYVRPAPSSRQFV
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEECCCEEECCCCCCCCHH
LLTLLARVVMQTLQRFYMATSLLLNSGQHSLSAEELENLCTVMAQRLSILHGLNAPEFFD
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHH
KTLFRHFIQSMQEQGVVSTDANGRLGYHEKLAELAEGAAKRVLPAEIRLSIRQVALERHH
HHHHHHHHHHHHHCCCEECCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
DDSEAPPPPTDA
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA