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The map label for this gene is blh [H]

Identifier: 146282864

GI number: 146282864

Start: 2754169

End: 2755917

Strand: Direct

Name: blh [H]

Synonym: PST_2523

Alternate gene names: 146282864

Gene position: 2754169-2755917 (Clockwise)

Preceding gene: 146282863

Following gene: 146282865

Centisome position: 60.3

GC content: 65.98

Gene sequence:

>1749_bases
ATGCAAACAATAAAACGACTGACCCCTTTTCTCTCCGTCGCGGCCCAGCTGCAACCGGCCGACATGGCACTGCTGGCCAG
CAATGGCTTCCGCTGCGTCATCAACAACCGTCCGGACAATGAGGGCGAGGGCCAGCCGTCGAGCGAGGCCATGCGCGCCG
CTGCCGAGGCGTCCGGCCTGGAGTATCACCATCTCCCGGTGGTATCCGGACAGATCACCGAAGCTGACGTTGCGGCCTTC
CGAGAACTGCTGGAACGGATCAAGGGCCCGGCCTTGGCCTTCTGCCGCACCGGTACCCGTTCGGCCTCACTCTGGGCGCT
GGCCGAGGCACACCATCTCGACCCACAGGTGCTGCTGCAAACTGCCCAGCAGGCAAGCTACGACCTCAGCGGCCTGCTGC
CGCGCATGCAGCAGTACTGGCAGTCGATCATCGACCAGCCGCTTCCGGCCGCCTCTACCTTTGCCGCCACACCGCGCTAC
GACGTTCTGGTGATCGGCGCTGGCGCGGCCGGCTGTGCAGTGACTGCCAGCCTGCTCAAGCGCGACCCCGAACTGCGCAT
CGCCCTCATCGAACCGCGTGATCAGCACTACTACCAGCCCGGCTGGACGCTGGTTGGGGCCGGCGTGTTCGACCGTGCCA
ATACCGAGCGCGCGATGAGCCGCTGCATTCCGTCCAGGGCACAGTGGATTCGCGCAGCCGCAGAGGCCTTCGAACCCGAG
CACCAGCAGGTGGTCCTCGAGGACGGCAGCCGCATCGGCTATCGTGCCCTGGTGGTCTGCCCGGGCCTGAGCCTCGACTG
GGACGCCATCGAAGGCGCCCGCGACAGCCTCGGCAAGTTCGGCGTGACCTCCAACTACGCCTTCGAGCTCGCACCCTACA
CCTGGCAGCTGGTGCAGAACCTGCGCGGCGGCAAGGCGCTGTTCACCCAGCCACCCATGCCGATCAAGTGTGCCGGCGCA
CCACAGAAGGCCATGTACCTGTCCTGCGATCACTGGCGCCAGCAAGGCGTACTGAAGGATATCGAGGTCGACTTCTGCTC
GGCCGGTGCAGTGCTGTTCGGCGTTGCCGACTTCGTACCCGCGCTGATGCAGTACGTCGAACGTTACGGTGCCCGACTGA
ACTTCAACCACTCCCTGGTGGCGGTGGACGGCCCCGCGCACAAGGCCTGGTTCAAGGTCACCGACGGCGCCGGACAGCAC
AGCACGGTGGAGCGGGACTTCGATCTGCTGCACCTGGTGCCGCCGCAGCACGCACCGGACTTCATCCGCCACAGCGCCCT
GGCCAACGCCGACGGCTGGTTCGAGGCCGAGCACGAGACGCTGCGGCATCCGCGCTTCGGCAATATCTTCAGCCTTGGCG
ACGTCTGCTCCGCGCCCAACGCGAAGACCGCCGCGGCGGTCCGCAAGCAGGCACCGGTGGTCGCCGAGAACGTGTTGAGC
GTACTCAAGGGCAGCGGCCCGCGGGCGCTCTACGACGGCTACGGTTCCTGCCCGCTGACCGTCGAGTACGGCAAGGTGAT
CCTCGCCGAGTTCGGCTACGGCGGAAAGCTGCTACCGACCTTCCCTCTCGACCCGAAGGTGCCGCGGCGGCTGGCCTGGA
AGCTGAAGACGCAATGGATGCCCTCGATCTACTTCGACATGATGCTCAAGGGGCATGAGTGGCTGGCCGAACCGAAGCAT
CTGGACTTCGAACCGCGCTCGGCCGAGGCACGCAACGCCTGCGACTTCACCCAGGAGAAGAAGGGATGA

Upstream 100 bases:

>100_bases
CATGCGCGGCGGCGAACTGCCCGAGCCCGAAAGCAACGGGACGCGCTACCTGAAGATCCCCCTGGACGTGCTGTAACCCC
CGAATGCGGAGGACGTCGAC

Downstream 100 bases:

>100_bases
AGCAGCGCCTGGCCCGCTATCTACCCATGCTGGCGTGGGCCAGGCACTACGATCGCGCGGCCGCGACGAAGGACAGTCTG
GCCGCACTGATCGTGACATT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 582; Mature: 582

Protein sequence:

>582_residues
MQTIKRLTPFLSVAAQLQPADMALLASNGFRCVINNRPDNEGEGQPSSEAMRAAAEASGLEYHHLPVVSGQITEADVAAF
RELLERIKGPALAFCRTGTRSASLWALAEAHHLDPQVLLQTAQQASYDLSGLLPRMQQYWQSIIDQPLPAASTFAATPRY
DVLVIGAGAAGCAVTASLLKRDPELRIALIEPRDQHYYQPGWTLVGAGVFDRANTERAMSRCIPSRAQWIRAAAEAFEPE
HQQVVLEDGSRIGYRALVVCPGLSLDWDAIEGARDSLGKFGVTSNYAFELAPYTWQLVQNLRGGKALFTQPPMPIKCAGA
PQKAMYLSCDHWRQQGVLKDIEVDFCSAGAVLFGVADFVPALMQYVERYGARLNFNHSLVAVDGPAHKAWFKVTDGAGQH
STVERDFDLLHLVPPQHAPDFIRHSALANADGWFEAEHETLRHPRFGNIFSLGDVCSAPNAKTAAAVRKQAPVVAENVLS
VLKGSGPRALYDGYGSCPLTVEYGKVILAEFGYGGKLLPTFPLDPKVPRRLAWKLKTQWMPSIYFDMMLKGHEWLAEPKH
LDFEPRSAEARNACDFTQEKKG

Sequences:

>Translated_582_residues
MQTIKRLTPFLSVAAQLQPADMALLASNGFRCVINNRPDNEGEGQPSSEAMRAAAEASGLEYHHLPVVSGQITEADVAAF
RELLERIKGPALAFCRTGTRSASLWALAEAHHLDPQVLLQTAQQASYDLSGLLPRMQQYWQSIIDQPLPAASTFAATPRY
DVLVIGAGAAGCAVTASLLKRDPELRIALIEPRDQHYYQPGWTLVGAGVFDRANTERAMSRCIPSRAQWIRAAAEAFEPE
HQQVVLEDGSRIGYRALVVCPGLSLDWDAIEGARDSLGKFGVTSNYAFELAPYTWQLVQNLRGGKALFTQPPMPIKCAGA
PQKAMYLSCDHWRQQGVLKDIEVDFCSAGAVLFGVADFVPALMQYVERYGARLNFNHSLVAVDGPAHKAWFKVTDGAGQH
STVERDFDLLHLVPPQHAPDFIRHSALANADGWFEAEHETLRHPRFGNIFSLGDVCSAPNAKTAAAVRKQAPVVAENVLS
VLKGSGPRALYDGYGSCPLTVEYGKVILAEFGYGGKLLPTFPLDPKVPRRLAWKLKTQWMPSIYFDMMLKGHEWLAEPKH
LDFEPRSAEARNACDFTQEKKG
>Mature_582_residues
MQTIKRLTPFLSVAAQLQPADMALLASNGFRCVINNRPDNEGEGQPSSEAMRAAAEASGLEYHHLPVVSGQITEADVAAF
RELLERIKGPALAFCRTGTRSASLWALAEAHHLDPQVLLQTAQQASYDLSGLLPRMQQYWQSIIDQPLPAASTFAATPRY
DVLVIGAGAAGCAVTASLLKRDPELRIALIEPRDQHYYQPGWTLVGAGVFDRANTERAMSRCIPSRAQWIRAAAEAFEPE
HQQVVLEDGSRIGYRALVVCPGLSLDWDAIEGARDSLGKFGVTSNYAFELAPYTWQLVQNLRGGKALFTQPPMPIKCAGA
PQKAMYLSCDHWRQQGVLKDIEVDFCSAGAVLFGVADFVPALMQYVERYGARLNFNHSLVAVDGPAHKAWFKVTDGAGQH
STVERDFDLLHLVPPQHAPDFIRHSALANADGWFEAEHETLRHPRFGNIFSLGDVCSAPNAKTAAAVRKQAPVVAENVLS
VLKGSGPRALYDGYGSCPLTVEYGKVILAEFGYGGKLLPTFPLDPKVPRRLAWKLKTQWMPSIYFDMMLKGHEWLAEPKH
LDFEPRSAEARNACDFTQEKKG

Specific function: Unknown

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI10864011, Length=405, Percent_Identity=35.0617283950617, Blast_Score=292, Evalue=5e-79,
Organism=Caenorhabditis elegans, GI17539680, Length=428, Percent_Identity=31.7757009345794, Blast_Score=234, Evalue=8e-62,
Organism=Caenorhabditis elegans, GI115534373, Length=332, Percent_Identity=36.7469879518072, Blast_Score=221, Evalue=1e-57,
Organism=Drosophila melanogaster, GI24657386, Length=384, Percent_Identity=34.6354166666667, Blast_Score=263, Evalue=2e-70,
Organism=Drosophila melanogaster, GI24657391, Length=384, Percent_Identity=34.6354166666667, Blast_Score=263, Evalue=2e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005939
- InterPro:   IPR001279 [H]

Pfam domain/function: PF04273 DUF442; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 63989; Mature: 63989

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTIKRLTPFLSVAAQLQPADMALLASNGFRCVINNRPDNEGEGQPSSEAMRAAAEASGL
CCHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEECCCCCCCCCCCCHHHHHHHHHHHCCC
EYHHLPVVSGQITEADVAAFRELLERIKGPALAFCRTGTRSASLWALAEAHHLDPQVLLQ
EEEECCEECCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHEEEHHHHCCCHHHHHH
TAQQASYDLSGLLPRMQQYWQSIIDQPLPAASTFAATPRYDVLVIGAGAAGCAVTASLLK
HHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCEEEEEECCCCHHHHHHHHHH
RDPELRIALIEPRDQHYYQPGWTLVGAGVFDRANTERAMSRCIPSRAQWIRAAAEAFEPE
CCCCEEEEEECCCCCCEECCCCEEEECCCCCCCCHHHHHHHHCCHHHHHHHHHHHHCCCC
HQQVVLEDGSRIGYRALVVCPGLSLDWDAIEGARDSLGKFGVTSNYAFELAPYTWQLVQN
CCEEEEECCCCCCEEEEEEECCCCCCHHHHCCHHHHHHCCCCCCCCEEEECCHHHHHHHH
LRGGKALFTQPPMPIKCAGAPQKAMYLSCDHWRQQGVLKDIEVDFCSAGAVLFGVADFVP
CCCCCEEECCCCCCEEECCCCCCEEEEEHHHHHHCCCHHHCCEEHHCCCHHHHHHHHHHH
ALMQYVERYGARLNFNHSLVAVDGPAHKAWFKVTDGAGQHSTVERDFDLLHLVPPQHAPD
HHHHHHHHHCCEECCCCEEEEECCCCCCEEEEEECCCCCCCCHHCCCCEEEECCCCCCHH
FIRHSALANADGWFEAEHETLRHPRFGNIFSLGDVCSAPNAKTAAAVRKQAPVVAENVLS
HHHHHHHCCCCCCEECCHHHHCCCCCCCEECCCCCCCCCCCHHHHHHHHCCCHHHHHHHH
VLKGSGPRALYDGYGSCPLTVEYGKVILAEFGYGGKLLPTFPLDPKVPRRLAWKLKTQWM
HHHCCCCCHHHCCCCCCCEEEECCCEEEEECCCCCEECCCCCCCCCCCHHHHHHHHHCCC
PSIYFDMMLKGHEWLAEPKHLDFEPRSAEARNACDFTQEKKG
HHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCCCCCHHCCCC
>Mature Secondary Structure
MQTIKRLTPFLSVAAQLQPADMALLASNGFRCVINNRPDNEGEGQPSSEAMRAAAEASGL
CCHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEECCCCCCCCCCCCHHHHHHHHHHHCCC
EYHHLPVVSGQITEADVAAFRELLERIKGPALAFCRTGTRSASLWALAEAHHLDPQVLLQ
EEEECCEECCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHEEEHHHHCCCHHHHHH
TAQQASYDLSGLLPRMQQYWQSIIDQPLPAASTFAATPRYDVLVIGAGAAGCAVTASLLK
HHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCEEEEEECCCCHHHHHHHHHH
RDPELRIALIEPRDQHYYQPGWTLVGAGVFDRANTERAMSRCIPSRAQWIRAAAEAFEPE
CCCCEEEEEECCCCCCEECCCCEEEECCCCCCCCHHHHHHHHCCHHHHHHHHHHHHCCCC
HQQVVLEDGSRIGYRALVVCPGLSLDWDAIEGARDSLGKFGVTSNYAFELAPYTWQLVQN
CCEEEEECCCCCCEEEEEEECCCCCCHHHHCCHHHHHHCCCCCCCCEEEECCHHHHHHHH
LRGGKALFTQPPMPIKCAGAPQKAMYLSCDHWRQQGVLKDIEVDFCSAGAVLFGVADFVP
CCCCCEEECCCCCCEEECCCCCCEEEEEHHHHHHCCCHHHCCEEHHCCCHHHHHHHHHHH
ALMQYVERYGARLNFNHSLVAVDGPAHKAWFKVTDGAGQHSTVERDFDLLHLVPPQHAPD
HHHHHHHHHCCEECCCCEEEEECCCCCCEEEEEECCCCCCCCHHCCCCEEEECCCCCCHH
FIRHSALANADGWFEAEHETLRHPRFGNIFSLGDVCSAPNAKTAAAVRKQAPVVAENVLS
HHHHHHHCCCCCCEECCHHHHCCCCCCCEECCCCCCCCCCCHHHHHHHHCCCHHHHHHHH
VLKGSGPRALYDGYGSCPLTVEYGKVILAEFGYGGKLLPTFPLDPKVPRRLAWKLKTQWM
HHHCCCCCHHHCCCCCCCEEEECCCEEEEECCCCCEECCCCCCCCCCCHHHHHHHHHCCC
PSIYFDMMLKGHEWLAEPKHLDFEPRSAEARNACDFTQEKKG
HHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]