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The map label for this gene is lolC [H]

Identifier: 146282861

GI number: 146282861

Start: 2751175

End: 2752395

Strand: Direct

Name: lolC [H]

Synonym: PST_2520

Alternate gene names: 146282861

Gene position: 2751175-2752395 (Clockwise)

Preceding gene: 146282860

Following gene: 146282862

Centisome position: 60.23

GC content: 67.81

Gene sequence:

>1221_bases
ATGCGCCTGGCCGATTCGCTGTGGACCGAATGGAAGATCGCCCTACGCTTCCTGCTGGACAACCGCATGCAGACGCTGCT
GATCACCTTCGGCATCGCCGTCGGTTCGGCGGTGATCGTCTTCATTACCGCCCTGATCACCGGCTTGCAGGCCAACGTCA
TCCAACGAACCCTCGGCACCCAGGCCCACATCCGCATCCTGCCCCCGGACGAGGTCAACCGCACGCTTCCAGCCGCCGCC
GACAGTTGGTCGCTGGTATTGGAAAGCCCGCGCGCCCAGCGTCTGCGTTCGATCATCAACTGGCAGGACGTGCGTGACGT
CCTCGACCAGGACGTGCAGATTCTCGCGGTGTCGCCGGTGATCAGCGGCCCGGCCATTGCCCGGCGCGGCGTCGCCCGGG
CCTCCGTGGCGCTGCTGGGCATCGATCCACCGCGTTATCAGCGCATCATCCCGCTGGCCGACGACCTGATCGCCGGCCGC
TTCCTGGTGGGTGCGGGCAACGCAGTGATCGGCAAGGAGCTGGCCCGCGACCTCGGCCTGGGCATCGGCGACAAGCTGCG
CCTGGATGCCGGCGAAGGCCGCGAAGCGGTCGTCGACATCGCCGGCATCTTCGAGCTGGGCGTGCGCGAGCTGGACGCGC
GCTACGTCTATCTCGACCTCAAGCAGGCGCAGACGCTGCTCGACCTGCCCGGCGGCGTGACAGTGATCGATACCACGGTC
GCCGAAATCTTCCAGGCCGACGAAGTTGCCAGGCGCCTGGCGCGCCTGACCGGGTTACGCGCCGAAAGCTGGATGGAAAC
CAACGGCCAGCTGCTCAACGCGCTCAGCTCGCAAAGCATGACCACCGAGATGATCCGTGTGTTCGTCGGCATCTCGGTGG
CCTTCGGCATCGCCAGCGTACTGGCCGTGAGTGTGGTCCAGCGTACCCGCGAGATCGGCATCCTGCGCGCCATGGGCAGC
CCGCGCGGGCAAATCCTGCGCGTATTCCTGCTGCAGGGCGGGCTACTCGGGCTGCTCGGCTCGGCCTGCGGCGGGCTGGT
CGGCTGGGGACTGGTGCAGGTGTTCAACCTGTTCGGCCCGCGGCTGTTCATCATTCCGGTCGACCCCACGCTGGTGCCGC
TGGCCATGCTGGTGGCGACGGTCACCGGCGTGCTGGCGGCGGCGATGCCCGCGCGACGTGCGGCGCGTTACGACCCGGCG
GTGGCGATCCGCTATGTGTGA

Upstream 100 bases:

>100_bases
CTGGAGGCCGGCGATCTGGTGCTGATCGGCGACGCCGAAGAAGGCCAGCGCGTGCGGCCGCGCGTACAACCCATCCCCAG
CGGCAGCCAGGACTGAGCGC

Downstream 100 bases:

>100_bases
ACGCGCACCAATGGCCCCTGCCGAGGAAGTCCTGCGCCTGGAACAGGTGCGCAAGGCCTTCAACATCGGCACACCCCTGG
AGACCGAAGTGCTGCACGGC

Product: lipoprotein release ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MRLADSLWTEWKIALRFLLDNRMQTLLITFGIAVGSAVIVFITALITGLQANVIQRTLGTQAHIRILPPDEVNRTLPAAA
DSWSLVLESPRAQRLRSIINWQDVRDVLDQDVQILAVSPVISGPAIARRGVARASVALLGIDPPRYQRIIPLADDLIAGR
FLVGAGNAVIGKELARDLGLGIGDKLRLDAGEGREAVVDIAGIFELGVRELDARYVYLDLKQAQTLLDLPGGVTVIDTTV
AEIFQADEVARRLARLTGLRAESWMETNGQLLNALSSQSMTTEMIRVFVGISVAFGIASVLAVSVVQRTREIGILRAMGS
PRGQILRVFLLQGGLLGLLGSACGGLVGWGLVQVFNLFGPRLFIIPVDPTLVPLAMLVATVTGVLAAAMPARRAARYDPA
VAIRYV

Sequences:

>Translated_406_residues
MRLADSLWTEWKIALRFLLDNRMQTLLITFGIAVGSAVIVFITALITGLQANVIQRTLGTQAHIRILPPDEVNRTLPAAA
DSWSLVLESPRAQRLRSIINWQDVRDVLDQDVQILAVSPVISGPAIARRGVARASVALLGIDPPRYQRIIPLADDLIAGR
FLVGAGNAVIGKELARDLGLGIGDKLRLDAGEGREAVVDIAGIFELGVRELDARYVYLDLKQAQTLLDLPGGVTVIDTTV
AEIFQADEVARRLARLTGLRAESWMETNGQLLNALSSQSMTTEMIRVFVGISVAFGIASVLAVSVVQRTREIGILRAMGS
PRGQILRVFLLQGGLLGLLGSACGGLVGWGLVQVFNLFGPRLFIIPVDPTLVPLAMLVATVTGVLAAAMPARRAARYDPA
VAIRYV
>Mature_406_residues
MRLADSLWTEWKIALRFLLDNRMQTLLITFGIAVGSAVIVFITALITGLQANVIQRTLGTQAHIRILPPDEVNRTLPAAA
DSWSLVLESPRAQRLRSIINWQDVRDVLDQDVQILAVSPVISGPAIARRGVARASVALLGIDPPRYQRIIPLADDLIAGR
FLVGAGNAVIGKELARDLGLGIGDKLRLDAGEGREAVVDIAGIFELGVRELDARYVYLDLKQAQTLLDLPGGVTVIDTTV
AEIFQADEVARRLARLTGLRAESWMETNGQLLNALSSQSMTTEMIRVFVGISVAFGIASVLAVSVVQRTREIGILRAMGS
PRGQILRVFLLQGGLLGLLGSACGGLVGWGLVQVFNLFGPRLFIIPVDPTLVPLAMLVATVTGVLAAAMPARRAARYDPA
VAIRYV

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=339, Percent_Identity=24.188790560472, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787105, Length=175, Percent_Identity=32.5714285714286, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787360, Length=310, Percent_Identity=25.8064516129032, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 43714; Mature: 43714

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLADSLWTEWKIALRFLLDNRMQTLLITFGIAVGSAVIVFITALITGLQANVIQRTLGT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QAHIRILPPDEVNRTLPAAADSWSLVLESPRAQRLRSIINWQDVRDVLDQDVQILAVSPV
CCEEEECCCHHCCCCCCCCCCCHHHHCCCHHHHHHHHHHCHHHHHHHHCCCCEEEEECCC
ISGPAIARRGVARASVALLGIDPPRYQRIIPLADDLIAGRFLVGAGNAVIGKELARDLGL
CCCHHHHHHCHHHHHEEEEECCCHHHHEECCCHHHHHHCEEEEECCCHHHHHHHHHHHCC
GIGDKLRLDAGEGREAVVDIAGIFELGVRELDARYVYLDLKQAQTLLDLPGGVTVIDTTV
CCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHCCCCCCEEEHHHH
AEIFQADEVARRLARLTGLRAESWMETNGQLLNALSSQSMTTEMIRVFVGISVAFGIASV
HHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAVSVVQRTREIGILRAMGSPRGQILRVFLLQGGLLGLLGSACGGLVGWGLVQVFNLFGP
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCC
RLFIIPVDPTLVPLAMLVATVTGVLAAAMPARRAARYDPAVAIRYV
EEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
>Mature Secondary Structure
MRLADSLWTEWKIALRFLLDNRMQTLLITFGIAVGSAVIVFITALITGLQANVIQRTLGT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QAHIRILPPDEVNRTLPAAADSWSLVLESPRAQRLRSIINWQDVRDVLDQDVQILAVSPV
CCEEEECCCHHCCCCCCCCCCCHHHHCCCHHHHHHHHHHCHHHHHHHHCCCCEEEEECCC
ISGPAIARRGVARASVALLGIDPPRYQRIIPLADDLIAGRFLVGAGNAVIGKELARDLGL
CCCHHHHHHCHHHHHEEEEECCCHHHHEECCCHHHHHHCEEEEECCCHHHHHHHHHHHCC
GIGDKLRLDAGEGREAVVDIAGIFELGVRELDARYVYLDLKQAQTLLDLPGGVTVIDTTV
CCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHCCCCCCEEEHHHH
AEIFQADEVARRLARLTGLRAESWMETNGQLLNALSSQSMTTEMIRVFVGISVAFGIASV
HHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAVSVVQRTREIGILRAMGSPRGQILRVFLLQGGLLGLLGSACGGLVGWGLVQVFNLFGP
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCC
RLFIIPVDPTLVPLAMLVATVTGVLAAAMPARRAARYDPAVAIRYV
EEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]